Research Topics
Species | E FrideSummaryAffiliation: College of Judea and Samaria Country: Israel Publications
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Detail Information
Publications
The endocannabinoid-CB(1) receptor system in pre- and postnatal lifeEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel
Eur J Pharmacol 500:289-97. 2004..The medical implications of these novel developments are far reaching and suggest a promising future for cannabinoids in pediatric medicine for conditions including "non-organic failure-to-thrive" and cystic fibrosis...- Endocannabinoids in the central nervous system--an overviewE Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel, 44837 Israel
Prostaglandins Leukot Essent Fatty Acids 66:221-33. 2002.... - Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthoodEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
Exp Biol Med (Maywood) 230:225-34. 2005..Furthermore, the role of cannabinoid CB1 receptor activation for milk suckling in newborns may open new doors toward understanding nonorganic failure-to-thrive in infants, who display growth failure without known organic cause... - (+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity onlyEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel
Eur J Pharmacol 506:179-88. 2004..We conclude that centrally inactive (+)-cannabidiol analogues should be further developed as antidiarrheal, antiinflammatory and analgesic drugs for gastrointestinal and other peripheral conditions... - The endocannabinoid-CB receptor system: Importance for development and in pediatric diseaseEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel
Neuro Endocrinol Lett 25:24-30. 2004..We suggest cannabinoid treatment for children or young adults with cystic fibrosis in order to achieve an improvement of their health condition including improved food intake and reduced inflammatory exacerbations... - Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptorEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel
Eur J Pharmacol 461:27-34. 2003..Our data also suggest that the CB(1)(-/-) neonates possess a compensatory mechanism which helps them overcome the lack of cannabinoid CB(1) receptors... - Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptorsEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel Department of Molecular Biology, College of Judea and Samaria, Ariel 44837, Israel
Neuropharmacology 48:1117-29. 2005..We propose to study the therapeutic potential of (-)- and (+)-CBD derivatives for complex conditions such as inflammatory bowel disease and cystic fibrosis... - Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal developmentE Fride
Department of Behavioural Sciences, Ariel University Center of Samaria, Ariel, Israel
J Neuroendocrinol 20:75-81. 2008.... - The endocannabinoid system: function in survival of the embryo, the newborn and the neuronEster Fride
Department of Behavioral Sciences, College of Judea, Ariel, Israel
Neuroreport 13:1833-41. 2002..Three physiological functions in which the endocannabinoids play a critical role are also discussed: embryonal implantation, feeding and appetite, and neuroprotection... - Differential response to acute and repeated stress in cannabinoid CB1 receptor knockout newborn and adult miceE Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
Behav Pharmacol 16:431-40. 2005.... - Inhibition of milk ingestion and growth after administration of a neutral cannabinoid CB1 receptor antagonist on the first postnatal day in the mouseEster Fride
Department of Behavioral Sciences, Ariel University Center of Samaria, Ariel 44837, Israel
Pediatr Res 62:533-6. 2007..This supports our hypothesis that endocannabinoid deficiency and perhaps CB1 receptor dysfunction represents the uncharacterized biologic vulnerability, which underlies NOFTT... - Endocannabinoids in the central nervous system: from neuronal networks to behaviorEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel 44837, Israel
Curr Drug Targets CNS Neurol Disord 4:633-42. 2005..The same ubiquity of the ECBR system however, should also be taken into consideration with respect to possible adverse side effects and addictive potential of such pharmaceutical developments... - Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectivenessNikolai Gobshtis
Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
Eur J Pharmacol 554:155-63. 2007..These observations suggest that combined treatment with antidepressants and cannabinoid CB(1) receptor antagonist to prevent undesirable weight gain, should be further investigated... - The endocannabinoid system during development: emphasis on perinatal events and delayed effectsEster Fride
Department of Behavioral Sciences and Molecular Biology, Ariel University Center of Samaria, Ariel, Israel
Vitam Horm 81:139-58. 2009.... - Behavioral methods in cannabinoid researchEster Fride
Department of Behavioral Sciences, College of Judea and Samaria, Ariel, Israel
Methods Mol Med 123:269-90. 2006.... - A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritisPercy F Sumariwalla
Kennedy Institute of Rheumatology, Imperial College London, London, UK
Arthritis Rheum 50:985-98. 2004..The profound suppressive effects on cellular immune responses and on the production of proinflammatory mediators all indicate its usefulness as a novel nonpsychoactive, synthetic antiinflammatory product... - Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brainArieh Moussaieff
Department of Medicinal Chemistry and Natural Products, Medical Faculty, Hebrew University of Jerusalem, 91120, Jerusalem, Israel
FASEB J 22:3024-34. 2008..Furthermore, the biochemical and pharmacological effects of IA may provide a biological basis for deeply rooted cultural and religious traditions... - Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodelingJoseph Tam
Bone Laboratory, Hebrew University of Jerusalem, PO Box 12272, Jerusalem 91120, Israel
Mol Pharmacol 70:786-92. 2006..Unraveling these differences can provide useful information on the physiologic functional milieu of CB1 in bone... - Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activationArieh Moussaieff
Department of Medicinal Chemistry and Natural Products, Medical Faculty, Hebrew University, Jerusalem 91120, Israel
Mol Pharmacol 72:1657-64. 2007..Cembrenoid diterpenoids, specifically IA and its derivatives, may thus constitute a potential novel group of NF-kappaB inhibitors, originating from an ancient anti-inflammatory herbal remedy... - Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiationDeborah Patinkin
Department of Pathology, Hebrew University, Medical Faculty, Jerusalem, Israel
Eur J Pharmacol 595:1-6. 2008..This is suggestive of some cross-talk between two different regulatory systems, one governed by glycoprotein ligands and the other by endocannabinoids... - Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptorsLumir O Hanus
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Medical Faculty, The Hebrew University of Jerusalem, Ein Kerem 91120, Jerusalem, Israel
Org Biomol Chem 3:1116-23. 2005..Some of these compounds also bind weakly to the CB(2) receptor...