R Bruck

Summary

Country: Israel

Publications

  1. ncbi request reprint Prevention of hepatic cirrhosis in rats by hydroxyl radical scavengers
    R Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    J Hepatol 35:457-64. 2001
  2. ncbi request reprint Pyrrolidine dithiocarbamate protects against thioacetamide-induced fulminant hepatic failure in rats
    Rafael Bruck
    Department of Gastroenterology, E Wolfson Medical Center, 58100, Holon, Israel
    J Hepatol 36:370-7. 2002
  3. ncbi request reprint Coffee and tea consumption and chronic liver disease
    Haim Shapiro
    Gastroenterology 130:1931-2; author reply 1932. 2006
  4. ncbi request reprint Prevention of liver cirrhosis in rats by curcumin
    Rafael Bruck
    The Department of Gastroenterology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Liver Int 27:373-83. 2007
  5. ncbi request reprint A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    Liver Int 24:169-76. 2004
  6. ncbi request reprint Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon 58100, Israel
    J Hepatol 40:86-93. 2004
  7. ncbi request reprint Non-peptidic analogs of the cell adhesion motif RGD prevent experimental liver injury
    R Bruck
    Department of Gastroenterology, Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 2:74-80. 2000
  8. ncbi request reprint Beta-carotene attenuates experimentally induced liver cirrhosis in rats
    J Wardi
    Department of Gastroenterology, Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 3:151-4. 2001
  9. pmc The use of synthetic analogues of Arg-Gly-Asp (RGD) and soluble receptor of tumor necrosis factor to prevent acute and chronic experimental liver injury
    R Bruck
    Department of Gastroenterology, E. Wolfson Medical Center, Holon, Israel
    Yale J Biol Med 70:391-402. 1997
  10. ncbi request reprint Amelioration of experimental colitis by thalidomide
    G Kenet
    Department of Gastroenterology, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Isr Med Assoc J 3:644-8. 2001

Collaborators

  • H Shirin
  • Y Niv
  • I R Cohen
  • Anat Ekka Zohar
  • Steven Moss
  • Nadir Arber
  • R Oren
  • M Boaz
  • Z Ackerman
  • Young Tak Kim
  • Ram Reifen
  • Joram Wardi
  • Arie Levine
  • Haim Shapiro
  • Hussein Aeed
  • Anat Ekka-Zohar
  • Gil Peretz
  • Alexandra Zanin-Zhorov
  • Mark Shahmurov
  • Shimon Reif
  • Yulia Gnainsky
  • Yona Avni
  • G Kenet
  • Pierre Singer
  • Zamir Halpern
  • Gabriela Link
  • Orit Pappo
  • Micha Mandel
  • Eitan Mor
  • Yana Zitser-Gurevich
  • Nir Weizman
  • Elisheva Simchen
  • Michal Ashkenazi
  • Sharon Nir
  • Inbal Weiss-Salz
  • Hadar Merhav
  • Nakash Richard
  • Guy Tal
  • Shirly Oren
  • Ofer Lider
  • Rami Hershkoviz
  • Benjamin Geiger
  • Melia Paizi
  • Yoel Kloog
  • Arnon Nagler
  • Gadi Spira
  • Reuven Reich
  • Young Oh Kweon
  • Suha Naffar Abu-Amara
  • Mark Pines
  • Efrat Monsonego-Ornan
  • Yael Shilo
  • Olga Genina
  • Shlomo Birkenfeld
  • Zipora Matas
  • L Zaidel
  • H Aeed
  • Y Avni
  • R Hershkoviz

Detail Information

Publications28

  1. ncbi request reprint Prevention of hepatic cirrhosis in rats by hydroxyl radical scavengers
    R Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    J Hepatol 35:457-64. 2001
    ..The aim of the present study was to examine whether the administration of free radical scavengers in vivo would prevent experimentally-induced hepatic cirrhosis in rats...
  2. ncbi request reprint Pyrrolidine dithiocarbamate protects against thioacetamide-induced fulminant hepatic failure in rats
    Rafael Bruck
    Department of Gastroenterology, E Wolfson Medical Center, 58100, Holon, Israel
    J Hepatol 36:370-7. 2002
    ....
  3. ncbi request reprint Coffee and tea consumption and chronic liver disease
    Haim Shapiro
    Gastroenterology 130:1931-2; author reply 1932. 2006
  4. ncbi request reprint Prevention of liver cirrhosis in rats by curcumin
    Rafael Bruck
    The Department of Gastroenterology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Liver Int 27:373-83. 2007
    ..The aim of the present study was to examine the efficacy of curcumin in preventing thioacetamide-induced cirrhosis and to unravel the mechanism of curcumin's effect on hepatic fibrosis in rats...
  5. ncbi request reprint A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    Liver Int 24:169-76. 2004
    ..The aim of the present study was to examine the efficacy of PDTC in a chronic rat model of thioacetamide (TAA)-induced hepatic fibrosis...
  6. ncbi request reprint Melatonin inhibits nuclear factor kappa B activation and oxidative stress and protects against thioacetamide induced liver damage in rats
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon 58100, Israel
    J Hepatol 40:86-93. 2004
    ..The aim of our study was to investigate whether melatonin, a potent free radical scavenger could prevent fulminant hepatic failure in rats...
  7. ncbi request reprint Non-peptidic analogs of the cell adhesion motif RGD prevent experimental liver injury
    R Bruck
    Department of Gastroenterology, Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 2:74-80. 2000
    ..The compounds described here may be examined therapeutically for pathological conditions in the liver, manifested as necro-inflammation and fibrosis...
  8. ncbi request reprint Beta-carotene attenuates experimentally induced liver cirrhosis in rats
    J Wardi
    Department of Gastroenterology, Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 3:151-4. 2001
    ..The mechanism may be related to effects on hepatic stellate cells or to scavenging of free radicals by beta-carotene. Retinolpalmitate and lycopen had no significant beneficial effect...
  9. pmc The use of synthetic analogues of Arg-Gly-Asp (RGD) and soluble receptor of tumor necrosis factor to prevent acute and chronic experimental liver injury
    R Bruck
    Department of Gastroenterology, E. Wolfson Medical Center, Holon, Israel
    Yale J Biol Med 70:391-402. 1997
    ..The compounds described here may be examined therapeutically for pathological conditions in the liver, manifested as necroinflammation, cholestasis and fibrosis...
  10. ncbi request reprint Amelioration of experimental colitis by thalidomide
    G Kenet
    Department of Gastroenterology, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Isr Med Assoc J 3:644-8. 2001
    ..CONCLUSIONS: Thalidomide effectively decreases colitis induced by iodoacetamide. The mechanism is probably associated with inhibition of TNF alpha, and should be further studied...
  11. ncbi request reprint Evaluation of a novel continuous real time (13)C urea breath analyser for Helicobacter pylori
    H Shirin
    Department of Gastroenterology, The E Wolfson Medical Center, Tel Aviv University, Tel Aviv, Israel
    Aliment Pharmacol Ther 15:389-94. 2001
    ..To evaluate the sensitivity and specificity of a new (13)C urea breath test, Oridion BreathID, for the diagnosis of Helicobacter pylori...
  12. ncbi request reprint Vanadate has no effect on insulin-extraction by the rat liver
    R Bruck
    Dept. of Gastroenterology, E. Wolfson Medical Center, Holon, Israel
    Horm Metab Res 26:360-2. 1994
    ..This study shows that vanadate does not inhibit insulin extraction by the perfused liver, and that does of vanadate that effectively inhibit hepatic glucose production possess no adverse effects on liver viability...
  13. ncbi request reprint Induced hypothyroidism accelerates the regression of liver fibrosis in rats
    Rafael Bruck
    Department of Gastrointestinal and Liver Diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    J Gastroenterol Hepatol 22:2189-94. 2007
    ..Therefore, in the present study, the potential therapeutic effect of hypothyroidism on liver fibrosis was investigated...
  14. ncbi request reprint Graft survival and its determinants: a 3 year national experience with liver transplantation in Israel
    Anat Ekka-Zohar
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Isr Med Assoc J 8:400-5. 2006
    ..There is a dearth of organs for liver transplantation in Israel. Enhancing our understanding of factors affecting graft survival in this country could help optimize the results of the transplant operation...
  15. ncbi request reprint Curcumin ameliorates acute thioacetamide-induced hepatotoxicity
    Haim Shapiro
    The Unit of Clinical Hypnosis, The E Wolfson Medical Center, Holon and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Gastroenterol Hepatol 21:358-66. 2006
    ..The aim of the present study is to assess curcumin's therapeutic potential in acute thioacetamide hepatotoxicity, a rat model of fulminant hepatic failure...
  16. ncbi request reprint Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis
    Yona Avni
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    J Med 34:121-37. 2003
    ..Nonalcoholic steatohepatitis is most often attributed to the effects of obesity, hyperlipidemia, diabetes mellitus and drugs. It is still unknown whether livers with steatohepatitis are more vulnerable to toxic damage...
  17. ncbi request reprint Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    Liver Int 25:613-21. 2005
    ..In the present study, we examined the ability of allicin to prevent immune-mediated, concanavalin A (Con A)-induced liver damage in mice...
  18. ncbi request reprint Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines
    Alexandra Zanin-Zhorov
    Department of Immunology, Weizmann Institute of Science, Rehovot, Israel
    J Immunol 174:3227-36. 2005
    ..These results provide a molecular explanation for the effects of HSP60 treatment on T cell inflammation via innate regulation of the inflammatory response...
  19. ncbi request reprint Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid
    Shimon Reif
    Department of Pediatric Gastroenterology, Tel Aviv, Souraski Medical Center, Tel Aviv, Israel
    J Hepatol 41:235-41. 2004
    ..The aim of the current study was to examine whether FTS will accelerate the resolution of liver cirrhosis induced in rats by thioacetamide...
  20. ncbi request reprint Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders
    Haim Shirin
    Department of Gastroenterology, Edith Wolfson Medical Center, Holon, Israel
    Isr Med Assoc J 4:24-7. 2002
    ..This discrepancy suggests that HCV lymphotropism or its effect on host lymphocytes may be influenced by regional and racial factors, as well as by genomic variations...
  21. ncbi request reprint Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes
    Yulia Gnainsky
    Institute of Animal Sciences, Agricultural Research Organization, The Volcani Center, PO Box 6, Bet Dagan 50250, Israel
    J Hepatol 40:269-77. 2004
    ..Halofuginone, an inhibitor of collagen synthesis, prevented and caused resolution of established hepatic fibrosis. A genomic approach in vivo was used to search for additional genes responsible for halofuginone mode of action...
  22. ncbi request reprint Glycine modulates cytokine secretion, inhibits hepatic damage and improves survival in a model of endotoxemia in mice
    Rafael Bruck
    Department of Gastroenterology, The E Wolfson Medical Center, Holon, Israel
    Liver Int 23:276-82. 2003
    ....
  23. ncbi request reprint Positive serology for Helicobacter pylori and vomiting in the pregnancy
    Haim Shirin
    Department of Gastroenterology, E Wolfson Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Holon, Israel
    Arch Gynecol Obstet 270:10-4. 2004
    ..The purpose of this study was to evaluate whether seropositivity for IgG antibodies to H. pylori may also be related to nausea, vomiting, heartburn and epigastric pain in pregnancy...
  24. ncbi request reprint Prognostic markers in gastrointestinal stromal tumors--we are not there yet
    Rafael Bruck
    Digestion 75:1-3. 2007
  25. ncbi request reprint Omega-3 may indirectly reduce hepatocyte triglycerides through modulation of hyperinsulinemia, cytokines and adipocytokines
    Haim Shapiro
    Am J Cardiol 99:146. 2007
  26. pmc Polyphenols in the treatment of inflammatory bowel disease and acute pancreatitis
    Haim Shapiro
    Gastroenterology Institute, Tel Aviv Sourasky Medical Center, Weizmann 6, Tel Aviv, Israel
    Gut 56:426-35. 2007
  27. pmc Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestatic liver disease
    Gil Peretz
    Department of Internal Medicine, Hebrew University Hadassah Medical Center, Mount Scopus Campus, PO Box 24035, Jerusalem 91240, Israel
    World J Gastroenterol 12:240-5. 2006
    ..To assess the effect of iron reduction after phlebotomy in rats with "normal" hepatic iron concentration (HIC) on the progression of hepatic fibrosis, as a result of bile duct ligation (BDL)...
  28. ncbi request reprint Effect of heparin on tissue binding activity of fibroblast growth factor and heparin-binding epidermal growth factor in experimental colitis in rats
    Arie Levine
    Pediatric Gastroenterology Service, Division of Gastroenterology, E Wolfson Medical Center, Holon, Israel
    Pediatr Res 51:635-40. 2002
    ..We suggest that one mechanism of heparin-mediated improvement in colitis may involve tissue healing associated with changes in functional levels of colonic growth factors...