Research Topics
Genomes and Genes | Hagit CohenSummaryAffiliation: Ben-Gurion University of the Negev Country: Israel Publications
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Detail Information
Publications
Reducing post-traumatic anxiety by immunizationGil M Lewitus
Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
Brain Behav Immun 22:1108-14. 2008....
The neuropeptide Y (NPY)-ergic system is associated with behavioral resilience to stress exposure in an animal model of post-traumatic stress disorderHagit Cohen
Anxiety and Stress Research Unit, Beer Sheva Mental Health Center, The State of Israel Ministry of Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Neuropsychopharmacology 37:350-63. 2012..The protective qualities attributed to NPY are supported by the extreme reduction of its expression in animals severely affected by the stressor and imply a role in promoting resilience and/or recovery...
Animal model for PTSD: from clinical concept to translational researchHagit Cohen
Israel Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, P O Box 4600, Beer Sheva 84170, Israel
Neuropharmacology 62:715-24. 2012..This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...
Long-lasting behavioral effects of juvenile trauma in an animal model of PTSD associated with a failure of the autonomic nervous system to recoverHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84170, Israel
Eur Neuropsychopharmacol 17:464-77. 2007....
Post-traumatic stress behavioural responses in inbred mouse strains: can genetic predisposition explain phenotypic vulnerability?Hagit Cohen
Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Int J Neuropsychopharmacol 11:331-49. 2008..The response of the individual to stress is multifactorial and environmental factors play a predominant role in characterizing the individual response to stress exposure, although there are significant genetic underpinnings...
Early post-stressor intervention with propranolol is ineffective in preventing posttraumatic stress responses in an animal model for PTSDHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur Neuropsychopharmacol 21:230-40. 2011..Traumatic stress-related processes appear to be affected differently than the others...
Decreased circulatory levels of neuroactive steroids in behaviourally more extremely affected rats subsequent to exposure to a potentially traumatic experienceHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Int J Neuropsychopharmacol 10:203-9. 2007....
Unsupervised fuzzy clustering analysis supports behavioral cutoff criteria in an animal model of posttraumatic stress disorderHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84170, Israel
Biol Psychiatry 58:640-50. 2005....
Anxiolytic effect and memory improvement in rats by antisense oligodeoxynucleotide to 5-hydroxytryptamine-2A precursor proteinHagit Cohen
Ben Gurion University of the Negev, Beer Sheva, Israel
Depress Anxiety 22:84-93. 2005..Receptor downregulation has been proposed as one of the central mechanisms for anxiolytic drug actions. Antisense-mediated downmanipulation of receptors in this study, especially of 5-HT2A, supports this theory...
Exposure to extreme stress impairs contextual odour discrimination in an animal model of PTSDHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Int J Neuropsychopharmacol 12:291-303. 2009....
Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorderHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Biol Psychiatry 64:708-17. 2008..We used an animal model of posttraumatic stress disorder (PTSD) to assess long-term behavioral effects of a single administration of various doses of corticosterone (CORT), administered immediately after exposure to psychogenic stress...
Anisomycin, a protein synthesis inhibitor, disrupts traumatic memory consolidation and attenuates posttraumatic stress response in ratsHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Biol Psychiatry 60:767-76. 2006....
An association between stress-induced disruption of the hypothalamic-pituitary-adrenal axis and disordered glucose metabolism in an animal model of post-traumatic stress disorderH Cohen
Beer Sheva Mental Health Center, The State of Israel Ministry of Health, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of Negev, Beer Sheva, Israel
J Neuroendocrinol 21:898-909. 2009..This metabolic response was associated with the characteristic pattern of HPA axis (corticosterone) response, which underlies the behavioural response to stress...
The contribution of an animal model toward uncovering biological risk factors for PTSDHagit Cohen
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84170, Israel
Ann N Y Acad Sci 1071:335-50. 2006....
The characteristic long-term upregulation of hippocampal NF-κB complex in PTSD-like behavioral stress response is normalized by high-dose corticosterone and pyrrolidine dithiocarbamate administered immediately after exposureHagit Cohen
The State of Israel Ministry of Health, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Neuropsychopharmacology 36:2286-302. 2011....
Gender differences in animal models of posttraumatic stress disorderHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Dis Markers 30:141-50. 2011..The examination of these gender-related differences can deepen our understanding of the risk or the pathophysiology of stress-related disorders...
Blunted HPA axis response to stress influences susceptibility to posttraumatic stress response in ratsHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Biol Psychiatry 59:1208-18. 2006..This study investigated the role of cortisol in the manifestation of anxiety- and fear-like symptoms in an animal model of PTSD...
Hippocampal microinfusion of oxytocin attenuates the behavioural response to stress by means of dynamic interplay with the glucocorticoid-catecholamine responsesH Cohen
Ministry of Health, Beer Sheva Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
J Neuroendocrinol 22:889-904. 2010..Oxytocin is actively involved in the neurobiological response to predator scent stress processes and thus warrants further study as a potential therapeutic avenue for the treatment of anxiety-related disorders...
Mapping the brain pathways of traumatic memory: inactivation of protein kinase M zeta in different brain regions disrupts traumatic memory processes and attenuates traumatic stress responses in ratsHagit Cohen
Ministry of Health, Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur Neuropsychopharmacol 20:253-71. 2010..Recent studies reported that local application of ZIP, a membrane-permeant PKMzeta inhibitor, into the insular cortex (IC) of behaving rats abolished long-term memory of taste associations...
The relationship between a common catechol-O-methyltransferase (COMT) polymorphism val(158) met and fibromyalgiaH Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Clin Exp Rheumatol 27:S51-6. 2009..The association between Val/Met polymorphism at the COMT gene was evaluated in FM disorder...
Protein synthesis inhibition before or after stress exposure results in divergent endocrine and BDNF responses disassociated from behavioral responsesNitsan Kozlovsky
Ministry of Health Beer Sheva Mental Health Center, Anxiety and Stress Research Unit, Ben Gurion University of the Negev, Beer Sheva, Israel
Depress Anxiety 25:E24-34. 2008....
The immediate early gene Arc is associated with behavioral resilience to stress exposure in an animal model of posttraumatic stress disorderNitsan Kozlovsky
Ministry of Health Beer Sheva Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, PO Box 4600, Beer Sheva 84170, Israel
Eur Neuropsychopharmacol 18:107-16. 2008....
Post-exposure sleep deprivation facilitates correctly timed interactions between glucocorticoid and adrenergic systems, which attenuate traumatic stress responsesShlomi Cohen
Department of Psychology, Ben Gurion University of the Negev, Beer Sheva, Israel
Neuropsychopharmacology 37:2388-404. 2012..Post-exposure SD may disrupt the consolidation of aversive or fearful memories by facilitating correctly timed interactions between glucocorticoid and adrenergic systems...
Long-term down-regulation of BDNF mRNA in rat hippocampal CA1 subregion correlates with PTSD-like behavioural stress responseNitsan Kozlovsky
Ministry of Health Beer Sheva Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Israel
Int J Neuropsychopharmacol 10:741-58. 2007..The corresponding changes in neural plasticity and synaptic functioning may mediate clinical manifestations of PTSD...
Pre-pubertal stress exposure affects adult behavioral response in association with changes in circulating corticosterone and brain-derived neurotrophic factorNoam Bazak
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, P O Box 4600, Beer Sheva 84170, Beer Sheva, Israel
Psychoneuroendocrinology 34:844-58. 2009..The concomitant changes in BDNF and corticosterone levels may mediate the changes in neural plasticity and synaptic functioning underlying clinical manifestations of PTSD...
High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: interplay between clinical and animal studiesJoseph Zohar
Division of Psychiatry, The State of Israel Ministry of Health, The Chaim Sheba Medical Center, Sackler Medical School, Tel Aviv University, Tel Hashomer, Israel
Eur Neuropsychopharmacol 21:796-809. 2011..Thus, evidence from clinical and animal studies suggests that there is a "window of opportunity" in the early aftermath of trauma to help those who are vulnerable to the development of chronic PTSD...
Gender-related qualitative differences in baseline and post-stress anxiety responses are not reflected in the incidence of criterion-based PTSD-like behaviour patternsAdi Mazor
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
World J Biol Psychiatry 10:856-69. 2009..In order to explore gender-related PTSD-like stress-responses more thoroughly, we applied an animal model that focuses selectively on individual patterns of behavioural responses...
The role of the galaninergic system in modulating stress-related responses in an animal model of posttraumatic stress disorderNitsan Kozlovsky
State of Israel Ministry of Health, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Biol Psychiatry 65:383-91. 2009....
A distinct pattern of intracellular glucocorticoid-related responses is associated with extreme behavioral response to stress in an animal model of post-traumatic stress disorderNitsan Kozlovsky
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur Neuropsychopharmacol 19:759-71. 2009..Glucocorticoids induce expression of Zif/268 through two distinct mechanisms: a rapid-onset, MAPK-independent pathway and a slower-onset, MAPK-dependent mechanism...
Different pathways mediated by CCK1 and CCK2 receptors: effect of intraperitonal mrna antisense oligodeoxynucleotides to cholecystokinin on anxiety-like and learning behaviors in ratsHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Depress Anxiety 20:139-52. 2004..The present study showed an anxiolytic effect of i.p. CCK-ASODN in the presence of CCK2R, but not CCK1R...
Alprazolam treatment immediately after stress exposure interferes with the normal HPA-stress response and increases vulnerability to subsequent stress in an animal model of PTSDMichael A Matar
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur Neuropsychopharmacol 19:283-95. 2009....
The effect of early poststressor intervention with sertraline on behavioral responses in an animal model of post-traumatic stress disorderMichael A Matar
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Neuropsychopharmacology 31:2610-8. 2006..SSRI drugs are thus worthy of further investigation as agents of secondary prevention in the acute aftermath of stress-exposure...
IFN-gamma enhances neurogenesis in wild-type mice and in a mouse model of Alzheimer's diseaseRona Baron
The Shraga Segal Dept of Microbiology and Immunology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
FASEB J 22:2843-52. 2008..We demonstrate that limited amounts of IFN-gamma in the brain shape the neuropoietic milieu to enhance neurogenesis, possibly representing the normal function of the immune system in controlling brain inflammation and repair...
Setting apart the affected: the use of behavioral criteria in animal models of post traumatic stress disorderHagit Cohen
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Neuropsychopharmacology 29:1962-70. 2004..As setting the affected individuals apart from the unaffected approximates clinical studies, it might also help to clarify some of the pending issues in PTSD research...
Irreversibility of cardiac autonomic dysfunction in female adolescents diagnosed with anorexia nervosa after short- and long-term weight gainMoshe Lachish
Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
World J Biol Psychiatry 10:503-11. 2009....
The effect of sudden clozapine discontinuation on management of schizophrenic patients: A retrospective controlled studyChanoch Miodownik
Division of Psychiatry, Ben Gurion University of the Negev, Beer Sheva, Israel
J Clin Psychiatry 67:1204-8. 2006....
Olfactory learning prevents MK-801-induced psychosis-like behaviour in an animal model of schizophreniaAri Naimark
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Ben Gurion University, Beer Sheva, Israel
World J Biol Psychiatry 9:135-46. 2008..Our data support the notion that learning-induced protection against schizophrenic behaviour is maintained by non-NMDA-mediated enhanced activation of local connections in the relevant cortical networks...
Chronic exposure to stress predisposes to higher autoimmune susceptibility in C57BL/6 mice: glucocorticoids as a double-edged swordIdan Harpaz
Anxiety and Stress Research Unit, Beer Sheva Mental Health Center, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur J Immunol 43:758-69. 2013....
[Vitamin B6 add-on therapy in treatment of schizophrenic patients with psychotic symptoms and movement disorders]Chanoch Miodownik
Ministry of Health, Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheba, Israel
Harefuah 142:592-6, 647. 2003..There is a need for further studies with larger samples and higher doses of vitamin B6 in order to examine the possibility of a positive therapeutic effect as an augmentation agent for the treatment of psychotic symptoms...
Maladaptation to mental stress mitigated by the adaptive immune system via depletion of naturally occurring regulatory CD4+CD25+ cellsHagit Cohen
Ministry of Health Mental Health Center Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
J Neurobiol 66:552-63. 2006..They might also point the way to development of immune-based therapies for mental disorders, based either on up-regulation of T cells that partially cross-react with self-antigens or on weakening of the activity of regulatory T cells...
The long-term abnormalities in circadian expression of Period 1 and Period 2 genes in response to stress is normalized by agomelatine administered immediately after exposureOri Koresh
Beer Sheva Mental Health Center, The State of Israel Ministry of Health, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Israel
Eur Neuropsychopharmacol 22:205-21. 2012....
Effect of intraperitoneal acetyl-L-carnitine (ALCAR) on anxiety-like behaviours in ratsJoseph Levine
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Int J Neuropsychopharmacol 8:65-74. 2005..The precise mechanism by which ALCAR decreases anxiety-like behaviour after peripheral administration remains to be determined...
The relevance of differential response to trauma in an animal model of posttraumatic stress disorderHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
Biol Psychiatry 53:463-73. 2003..Overlooking this heterogeneity may obscure the results of data analysis. CONCLUSIONS: Animals can be divided into distinct groups according to magnitude of response and be studied accordingly...
Prevalence of post-traumatic stress disorder in fibromyalgia patients: overlapping syndromes or post-traumatic fibromyalgia syndrome?Hagit Cohen
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Semin Arthritis Rheum 32:38-50. 2002..The influence of gender on measures of PTSD in fibromyalgia (FM) patients also was examined...
Effect of intraperitoneal mRNA antisense-oligodeoxynucleotides to cholecystokinin on anxiety-like and learning behaviors in rats: association with pre-experimental stressHagit Cohen
Ministry of Health Mental Health Center, Faculty of Health Sciences, Anxiety and Stress Research Unit, Ben Gurion University of the Negev, Beer Sheva, Israel
Neuropeptides 36:341-52. 2002..We demonstrated that intracerebroventricular administration of Cholecystokinin-antisense oligodeoxynucleotides (ASODN) for 3 days significantly diminished anxiety-like behavior in rats...
An animal model of posttraumatic stress disorder: the use of cut-off behavioral criteriaHagit Cohen
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, P O Box 4600, Beer Sheva 84170, Israel
Ann N Y Acad Sci 1032:167-78. 2004..Overlooking heterogeneity in responses obscures the results of biobehavioral data analysis. We submit that animals exposed to trauma should be divided into groups according to the magnitude of their response and be studied accordingly...
Post-traumatic stress disorder is not over-represented in a sample population of migraine patientsGal Ifergane
Headache Clinic, Department of Neurology, Soroka Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur J Intern Med 20:182-5. 2009..PTSD was previously associated with chronic pain and primary pain disorders...
Stress-related responses after 3 years of exposure to terror in Israel: are ideological-religious factors associated with resilience?Zeev Kaplan
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
J Clin Psychiatry 66:1146-54. 2005....
Effects of the cortisol synthesis inhibitor metyrapone on the response to carbon dioxide challenge in panic disorderAndrey Belgorodsky
Division of Psychiatry, Ben Gurion University of the Negev, Beer-Sheba, Israel
Depress Anxiety 21:143-8. 2005..The results support an anxiogenic role for cortisol in stress, and suggest that the pathophysiological mechanism that mediates CO2-induced panic differs from those underlying other kinds of anxiety...
Power spectrum analysis and cardiovascular morbidity in anxiety disordersHagit Cohen
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben Gurion University of the Negev, P O Box 4600, Beer Sheva, Israel
Auton Neurosci 128:1-8. 2006..The authors call for further studies, especially in patients with co-existing anxiety disorders and heart disease, incorporating assessment of HRV...
Impaired heart rate variability in euthymic bipolar patientsHagit Cohen
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Bipolar Disord 5:138-43. 2003..Power spectral analysis of heart rate variability (HRV) has recently been shown to be a reliable non-invasive test for quantitative assessment of the central sympathovagal interaction that modulates cardiovascular autonomic function...
The quantitative electroencephalogram and the low-resolution electrical tomographic analysis in posttraumatic stress disorderDoran Todder
Ben Gurion University, Faculty of Health, Beer Sheva, Israel
Clin EEG Neurosci 43:48-53. 2012..These results indicate that combining quantitative EEG (QEEG) and the LORETA method, among other methods, may improve the neuroanatomical resolution of EEG data analysis...
Repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal cortex in posttraumatic stress disorder: a double-blind, placebo-controlled studyHagit Cohen
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Am J Psychiatry 161:515-24. 2004..The efficacy of repetitive transcranial magnetic stimulation (rTMS) of the right prefrontal cortex was studied in patients with posttraumatic stress disorder (PTSD) under double-blind, placebo-controlled conditions...
[A model for therapeutic interventions in emotional responses to enforced geographical relocation of populations in Israel]Zeev Kaplan
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Harefuah 144:234-6, 304. 2005..These principles seem to us far more suited to the demands of the complex situation ahead, in order to provide relief and assist in adaptation, and to prevent later complications of possible emotional sequelae...
Accuracy of the diagnosis of fibromyalgia by family physicians: is the pendulum shifting?Elena Shleyfer
Department of Medicine, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, PO Box 653, Beer Sheva 84105, Israel
J Rheumatol 36:170-3. 2009..We evaluated the accuracy of diagnosis of fibromyalgia (FM) by family physicians...
Upregulation of neurotrophic factors selectively in frontal cortex in response to olfactory discrimination learningAri Naimark
Anxiety and Stress Research Unit, Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Neural Plast 2007:13427. 2007..These findings suggest that different brain areas may be preferentially involved in different learning/memory tasks...
Comorbidity of fibromyalgia and psychiatric disordersDan Buskila
Department of Medicine H, Soroka Medical Center, POB 151, Beer Sheva 84101, Israel
Curr Pain Headache Rep 11:333-8. 2007..Assessment of comorbid psychiatric disorders in FMS patients has clinical implications because treatment in these patients should focus both on physical and emotional dimensions of dysfunction...
Symptoms of posttraumatic stress disorder after ritual female genital surgery among bedouin in Israel: myth or reality?Julia Applebaum
Ministry of Health, Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva and Clalit Health Services, Family Health Center, Rahat, Israel
Prim Care Companion J Clin Psychiatry 10:453-6. 2008..This pilot study assessed the mental health of Bedouin women from southern Israel after RFGS compared to age-matched controls without RFGS...
Immunity and neuronal repair in the progression of Alzheimer's disease: a brief overviewRona Baron
Department of Microbiology and Immunology and National Institute of Biotechnology in Negev, Faculty of Health Sciences, Ben Gurion University of Negev, PO Box 653, Beer Sheva 84105, Israel
Exp Gerontol 42:64-9. 2007....
A naturalistic prospective open study of the effects of adjunctive therapy of sexual dysfunction in chronic PTSD patientsBela Chudakov
Ministry of Health, Mental Health Center, Faculty of Health Sciences, Anxiety and Stress Research Unit, Ben Gurion University of the Negev, Beersheba, Israel
Isr J Psychiatry Relat Sci 45:26-32. 2008..This prospective naturalistic follow-up study of a random group of patients was intended to evaluate response to pharmacologic and psychotherapeutic interventions for SD, in terms of both sexual functioning and overall symptomatology...
Vitamin B6 as add-on treatment in chronic schizophrenic and schizoaffective patients: a double-blind, placebo-controlled studyVladimir Lerner
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Be er Sheva, Israel
J Clin Psychiatry 63:54-8. 2002..The aim of this study was to examine whether vitamin B6 therapy influences psychotic symptoms in patients suffering from schizophrenia and schizoaffective disorder...
Coping styles in fibromyalgia: effect of co-morbid posttraumatic stress disorderJacob N Ablin
Institute of Rheumatology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, 6 Weizman St, Tel Aviv 64239, Israel
Rheumatol Int 28:649-56. 2008..Our results may serve to further characterize cognitive and behavioral aspects of FM patients and subsequently guide therapeutic interventions...
Relationship between antidepressants and IGF-1 system in the brain: possible role in cognitionNurit Grunbaum-Novak
Lab of Biological Psychiatry, Felsenstein Medical Research Center and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel
Eur Neuropsychopharmacol 18:431-8. 2008..FLX did not affect cognitive performance. Thus, repeated FLX treatment leads to upregulation of IGF-1 system is FC. It is possible that FLX affect FC neuroplasticity through activation of the IGF-1 system...
Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophreniaYechiel Levkovitz
The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
Brain Res 1154:154-62. 2007..The discussion addresses potential mechanisms underlying the effects of minocycline and possible directions for future research...
Activity and plasticity in the CA1, the dentate gyrus, and the amygdala following controllable vs. uncontrollable water stressAlexandra Kavushansky
Department of Psychology and Brain and Behavior Research Center, University of Haifa, Israel
Hippocampus 16:35-42. 2006..These findings provide insight into the differential effects of stress and stress controllability on different hippocampal subregions and the amygdala...
Juvenile stress induces a predisposition to either anxiety or depressive-like symptoms following stress in adulthoodMichael Tsoory
Department of Psychology and The Brain and Behavior Research Center, University of Haifa, Mount Carmel, 31905 Haifa, Israel
Eur Neuropsychopharmacol 17:245-56. 2007..The results suggest that the presented "Juvenile stress" model may be relevant to the reported predisposition to develop both anxiety and depression following childhood trauma...
T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditionsJonathan Kipnis
Department of Neurobiology, Weizmann Institute of Science, 76100 Rehovot, Israel
Proc Natl Acad Sci U S A 101:8180-5. 2004..These findings point to critical factors likely to contribute to age- and AIDS-related dementias and might herald the development of a therapeutic vaccination for fighting off cognitive dysfunction and psychiatric conditions...
Outcomes of naltrexone maintenance following ultra rapid opiate detoxification versus intensive inpatient detoxificationJonathan Rabinowitz
School of Social Work, Bar Ilan University, Ramat Gan, Israel
Am J Addict 11:52-6. 2002..4 (+/- 3.8) months after detoxification. Naltrexone maintenance and counseling following rapid detoxification may be as effective as intensive inpatient detoxification and counseling...
Confirmation of an association between fibromyalgia and serotonin transporter promoter region (5- HTTLPR) polymorphism, and relationship to anxiety-related personality traitsHagit Cohen
Arthritis Rheum 46:845-7. 2002
Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthoodYaniv Ziv
Department of Neurobiology, Weizmann Institute of Science, 76100 Rehovot, Israel
Nat Neurosci 9:268-75. 2006....
Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1Oleg Butovsky
Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
Proc Natl Acad Sci U S A 103:11784-9. 2006..These results suggest that dendritic-like microglia, by facilitating the necessary adjustment, might contribute significantly to the brain's resistance to AD and argue against the use of antiinflammatory drugs...
Mechanisms of Disease: genetics of fibromyalgiaJacob N Ablin
Department of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv University, 6 Weizman Street, Tel Aviv 64239, Israel
Nat Clin Pract Rheumatol 2:671-8. 2006....
