Sofia Avissar

Summary

Affiliation: Ben-Gurion University of the Negev
Country: Israel

Publications

  1. ncbi request reprint Beta-arrestin signaling complex as a target for antidepressants and as a depression marker
    Gabriel Schreiber
    Department of Psychiatry of Ben Gurion University of the Negev, Beer Sheva, Israel
    Drug News Perspect 22:467-80. 2009
  2. ncbi request reprint Measurement of early events in signal transduction beyond receptors involving G proteins function in mononuclear leucocytes
    S Avissar
    Department of Clinical Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    J Neuroimmunol 70:81-6. 1996
  3. ncbi request reprint The effects of seasons and light therapy on G protein levels in mononuclear leukocytes of patients with seasonal affective disorder
    S Avissar
    Department of Clinical Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Arch Gen Psychiatry 56:178-83. 1999
  4. ncbi request reprint Elevated dopamine receptor-coupled G(s) protein measures in mononuclear leukocytes of patients with schizophrenia
    S Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Schizophr Res 47:37-47. 2001
  5. ncbi request reprint Differential effects of the antipsychotics haloperidol and clozapine on G protein measures in mononuclear leukocytes of patients with schizophrenia
    S Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Cell Mol Neurobiol 21:799-811. 2001
  6. ncbi request reprint Toward molecular diagnostics of mood disorders in psychiatry
    Sofia Avissar
    Dept of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva, 84105 Israel
    Trends Mol Med 8:294-300. 2002
  7. ncbi request reprint Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain
    Sofia Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, P O Box 653, Beer Sheva 84105, Israel
    Am J Psychiatry 161:2066-72. 2004
  8. doi request reprint Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway
    Moran Golan
    Department of Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Int J Neuropsychopharmacol 14:1289-300. 2011
  9. ncbi request reprint Application of G-proteins in the molecular diagnosis of psychiatric disorders
    Gabriel Schreiber
    Division of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, 84105 Israel
    Expert Rev Mol Diagn 3:69-80. 2003
  10. doi request reprint Normalization of GRK2 protein and mRNA measures in patients with depression predict response to antidepressants
    Angela Matuzany-Ruban
    Department of Pharmacology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Int J Neuropsychopharmacol 13:83-91. 2010

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Beta-arrestin signaling complex as a target for antidepressants and as a depression marker
    Gabriel Schreiber
    Department of Psychiatry of Ben Gurion University of the Negev, Beer Sheva, Israel
    Drug News Perspect 22:467-80. 2009
    ....
  2. ncbi request reprint Measurement of early events in signal transduction beyond receptors involving G proteins function in mononuclear leucocytes
    S Avissar
    Department of Clinical Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    J Neuroimmunol 70:81-6. 1996
    ....
  3. ncbi request reprint The effects of seasons and light therapy on G protein levels in mononuclear leukocytes of patients with seasonal affective disorder
    S Avissar
    Department of Clinical Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Arch Gen Psychiatry 56:178-83. 1999
    ..In this study, patients with seasonal affective disorder (SAD) were measured for mononuclear leukocyte G protein levels while depressed during the winter, following light therapy, and in remission during the summer...
  4. ncbi request reprint Elevated dopamine receptor-coupled G(s) protein measures in mononuclear leukocytes of patients with schizophrenia
    S Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Schizophr Res 47:37-47. 2001
    ....
  5. ncbi request reprint Differential effects of the antipsychotics haloperidol and clozapine on G protein measures in mononuclear leukocytes of patients with schizophrenia
    S Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Cell Mol Neurobiol 21:799-811. 2001
    ....
  6. ncbi request reprint Toward molecular diagnostics of mood disorders in psychiatry
    Sofia Avissar
    Dept of Clinical Pharmacology, Ben Gurion University of the Negev, Beer Sheva, 84105 Israel
    Trends Mol Med 8:294-300. 2002
    ..New-era methods and strategies involving genomics, proteomics, multi-marker approach and single nucleotide polymorphisms have the potential to revolutionize future diagnosis in psychiatry...
  7. ncbi request reprint Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain
    Sofia Avissar
    Department of Clinical Pharmacology, Ben Gurion University of the Negev, P O Box 653, Beer Sheva 84105, Israel
    Am J Psychiatry 161:2066-72. 2004
    ..The present study aims at quantitatively evaluating beta-arrestin-1 levels in leukocytes of patients with major depression and the effect of antidepressants on beta-arrestin-1 levels in rat brain...
  8. doi request reprint Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway
    Moran Golan
    Department of Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Int J Neuropsychopharmacol 14:1289-300. 2011
    ....
  9. ncbi request reprint Application of G-proteins in the molecular diagnosis of psychiatric disorders
    Gabriel Schreiber
    Division of Psychiatry, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, 84105 Israel
    Expert Rev Mol Diagn 3:69-80. 2003
    ..The accumulated data supports the potential use of G-protein measures as state-dependent markers for the biochemical diagnosis of mental disorders and as aid in the biochemical monitoring of the response to a specific treatment...
  10. doi request reprint Normalization of GRK2 protein and mRNA measures in patients with depression predict response to antidepressants
    Angela Matuzany-Ruban
    Department of Pharmacology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Int J Neuropsychopharmacol 13:83-91. 2010
    ..GRK2 measurements in patients with depression may potentially serve for biochemical diagnostic purposes and for monitoring and predicting response to antidepressants...
  11. ncbi request reprint Phosducin-like protein levels in leukocytes of patients with major depression and in rat cortex: the effect of chronic treatment with antidepressants
    Angela Matuzany-Ruban
    Department of Pharmacology, P O Box 653, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Psychiatry Res 141:287-94. 2006
    ..No protein changes were found in leukocytes of either untreated patients with major depressive disorder or after 4 weeks of the treatment in comparison with healthy volunteers...
  12. ncbi request reprint The involvement of G proteins and regulators of receptor-G protein coupling in the pathophysiology, diagnosis and treatment of mood disorders
    Sofia Avissar
    Department of Pharmacology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Clin Chim Acta 366:37-47. 2006
    ....
  13. ncbi request reprint Regulators of G-protein-coupled receptor-G-protein coupling: antidepressants mechanism of action
    Gabriel Schreiber
    Ben Gurion University of the Negev, Dept of Psychiatry at Barzilai Medical Center, Ashkelon, Israel
    Expert Rev Neurother 7:75-84. 2007
    ....
  14. doi request reprint Antidepressants increase β-arrestin 2 ubiquitinylation and degradation by the proteasomal pathway in C6 rat glioma cells
    Moran Golan
    Department of Pharmacology, Ben Gurion University of the Negev, P O Box 653, Beer Sheva, Israel 84105
    J Pharmacol Exp Ther 332:970-6. 2010
    ....
  15. doi request reprint Antidepressant-induced differential ubiquitination of β-arrestins 1 and 2 in mononuclear leucocytes of patients with depression
    Moran Golan
    Department of Clinical Biochemistry and Pharmacology, Faculty for Health Sciences, Ben Gurion University of the Negev, Israel
    Int J Neuropsychopharmacol 16:1745-54. 2013
    ....
  16. ncbi request reprint Editorial: Complexity and future of biochemical differential diagnosis in psychiatry
    Gabriel Schreiber
    Isr J Psychiatry Relat Sci 41:79-81. 2004