Mira Barda-Saad

Summary

Affiliation: Bar-Ilan University
Country: Israel

Publications

  1. pmc Cooperative interactions at the SLP-76 complex are critical for actin polymerization
    Mira Barda-Saad
    Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel
    EMBO J 29:2315-28. 2010
  2. doi request reprint Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET
    Maor H Pauker
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    Sci Signal 5:rs3. 2012
  3. pmc Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics
    Barak Reicher
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel
    Mol Cell Biol 32:3153-63. 2012
  4. pmc Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization
    Maor H Pauker
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    Mol Cell Biol 31:2653-66. 2011

Collaborators

Detail Information

Publications4

  1. pmc Cooperative interactions at the SLP-76 complex are critical for actin polymerization
    Mira Barda-Saad
    Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel
    EMBO J 29:2315-28. 2010
    ..Disruption of the VAV1:Nck interaction deleteriously affected actin polymerization. These novel findings shed new light on the mechanism of actin polymerization after T-cell activation...
  2. doi request reprint Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET
    Maor H Pauker
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    Sci Signal 5:rs3. 2012
    ..We suggest that these findings revise the accepted model of the formation of a complex of SLP-76, Nck, and Vav1 and demonstrate the use of 3FRET as a tool to study signal transduction in live cells...
  3. pmc Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics
    Barak Reicher
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel
    Mol Cell Biol 32:3153-63. 2012
    ..Our data suggest that regulated degradation of activated WASp might be an efficient strategy by which the duration and localization of actin rearrangement and the intensity of T-cell activation are controlled...
  4. pmc Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization
    Maor H Pauker
    The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
    Mol Cell Biol 31:2653-66. 2011
    ..Functional cooperation between Nck and ADAP mediates SLP76-WASp interactions and actin rearrangement. We also reveal the molecular mechanism linking ADAP to actin reorganization...