Tauheed Ishrat

Summary

Publications

  1. doi request reprint Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
    Tauheed Ishrat
    Department of Medical Elementology and Toxicology, Neurotoxicology Laboratory, Jamia Hamdard Hamdard University, New Delhi, India
    Brain Res 1281:117-27. 2009
  2. ncbi request reprint Behavioral and histologic neuroprotection of aqueous garlic extract after reversible focal cerebral ischemia
    Sofiyan Saleem
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    J Med Food 9:537-44. 2006
  3. doi request reprint Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease
    Mohd Moshahid Khan
    Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    Brain Res 1328:139-51. 2010
  4. ncbi request reprint Attenuation by Nardostachys jatamansi of 6-hydroxydopamine-induced parkinsonism in rats: behavioral, neurochemical, and immunohistochemical studies
    Muzamil Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Pharmacol Biochem Behav 83:150-60. 2006
  5. doi request reprint Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats
    Mohd Moshahid Khan
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology Fund for the Improvement of Science and Technology sponsored by DST and Special Assistance Programme sponsored by UGC, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Chem Biol Interact 183:255-63. 2010
  6. doi request reprint Effects of Pycnogenol and vitamin E on cognitive deficits and oxidative damage induced by intracerebroventricular streptozotocin in rats
    Tauheed Ishrat
    Department of Medical Elementology and Toxicology, Neurotoxicology Laboratory, Jamia Hamdard Hamdard University, New Delhi, India
    Behav Pharmacol 20:567-75. 2009
  7. ncbi request reprint Effect of Saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats
    Sofiyan Saleem
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard University, Hamdard Nagar, New Delhi, India
    J Med Food 9:246-53. 2006
  8. doi request reprint Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat
    Ajmal Ahmad
    Department of Medical Elementology and Toxicology Fund for the Improvement of Science and Technology DST and Special Assistance Programme UGC Sponsored, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    Mol Cell Biochem 367:215-25. 2012
  9. ncbi request reprint Effect of dietary sesame oil as antioxidant on brain hippocampus of rat in focal cerebral ischemia
    Saif Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard Hamdard University, New Delhi 110 062, India
    Life Sci 79:1921-8. 2006
  10. doi request reprint Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease
    Mohammad Moshahid Khan
    Department of Medical Elementology and Toxicology, Jamia Hamdard, Hamdard University, Hamdard Nagar, New Delhi, India
    Behav Pharmacol 21:563-71. 2010

Collaborators

Detail Information

Publications24

  1. doi request reprint Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
    Tauheed Ishrat
    Department of Medical Elementology and Toxicology, Neurotoxicology Laboratory, Jamia Hamdard Hamdard University, New Delhi, India
    Brain Res 1281:117-27. 2009
    ..Our study reveals that Se, as a powerful antioxidant, prevents cognitive deficits, oxidative damage and morphological changes in the ICV-STZ rats. Thus, it may have a therapeutic value for the treatment of SDAT...
  2. ncbi request reprint Behavioral and histologic neuroprotection of aqueous garlic extract after reversible focal cerebral ischemia
    Sofiyan Saleem
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    J Med Food 9:537-44. 2006
    ..These findings suggest that AGE effectively modulates neurobehavioral and neurochemical changes in focal ischemia, most probably by virtue of its antioxidant properties...
  3. doi request reprint Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease
    Mohd Moshahid Khan
    Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    Brain Res 1328:139-51. 2010
    ..Thus, RES may be used to reduce the deterioration caused by free radicals thereby preventing subsequent behavioral, biochemical, and histopathological changes that occur during PD...
  4. ncbi request reprint Attenuation by Nardostachys jatamansi of 6-hydroxydopamine-induced parkinsonism in rats: behavioral, neurochemical, and immunohistochemical studies
    Muzamil Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Pharmacol Biochem Behav 83:150-60. 2006
    ..This study indicates that the extract of Jatamansi might be helpful in attenuating Parkinsonism...
  5. doi request reprint Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats
    Mohd Moshahid Khan
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology Fund for the Improvement of Science and Technology sponsored by DST and Special Assistance Programme sponsored by UGC, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Chem Biol Interact 183:255-63. 2010
    ..Thus, sesamin may be a potential compound in stroke therapy...
  6. doi request reprint Effects of Pycnogenol and vitamin E on cognitive deficits and oxidative damage induced by intracerebroventricular streptozotocin in rats
    Tauheed Ishrat
    Department of Medical Elementology and Toxicology, Neurotoxicology Laboratory, Jamia Hamdard Hamdard University, New Delhi, India
    Behav Pharmacol 20:567-75. 2009
    ..These findings suggest that PYC and Vit E may provide a promising approach for the treatment of oxidative stress-related neurodegeneration in conditions such as AD...
  7. ncbi request reprint Effect of Saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats
    Sofiyan Saleem
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard University, Hamdard Nagar, New Delhi, India
    J Med Food 9:246-53. 2006
    ..The present results may suggest the effectiveness of CS in focal ischemia most probably by virtue of its antioxidant property...
  8. doi request reprint Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat
    Ajmal Ahmad
    Department of Medical Elementology and Toxicology Fund for the Improvement of Science and Technology DST and Special Assistance Programme UGC Sponsored, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, India
    Mol Cell Biochem 367:215-25. 2012
    ..We theorized that Edv is among the pharmacological agents that reduce free radicals and its associated cholinergic dysfunction and apoptotic damage and have been found to limit the extent of brain damage following stroke...
  9. ncbi request reprint Effect of dietary sesame oil as antioxidant on brain hippocampus of rat in focal cerebral ischemia
    Saif Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard Hamdard University, New Delhi 110 062, India
    Life Sci 79:1921-8. 2006
    ..The results of neurobehavioral activity also support our biochemical data. The results obtained suggest protective effect of SO against cerebral ischemia in rat brain through their antioxidant properties...
  10. doi request reprint Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease
    Mohammad Moshahid Khan
    Department of Medical Elementology and Toxicology, Jamia Hamdard, Hamdard University, Hamdard Nagar, New Delhi, India
    Behav Pharmacol 21:563-71. 2010
    ..Thus, PYC may be used to prevent or reduce the deterioration caused by free radicals, thereby preventing subsequent behavioural and biochemical changes that occur in Parkinsonian mice...
  11. ncbi request reprint Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats
    Tauheed Ishrat
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, New Delhi, India
    Behav Brain Res 171:9-16. 2006
    ..However, supplementation with CoQ10 in STZ-infused rats reversed all the parameters significantly. Thus, the study demonstrates that CoQ10 may have a therapeutic importance in the treatment of Alzheimer's type dementia...
  12. doi request reprint Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
    Seema Yousuf
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, New Delhi 110062, India
    Brain Res 1250:242-53. 2009
    ..The findings of this study highlight the ability of resveratrol in anatomical and functional preservation of ischemic neurovascular units and its relevance in the treatment of ischemic stroke...
  13. doi request reprint Neuroprotective efficacy of Nardostachys jatamansi and crocetin in conjunction with selenium in cognitive impairment
    M Badruzzaman Khan
    Department of Medical Elementology and Toxicology, Neurotoxicology Laboratory, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Neurol Sci 33:1011-20. 2012
    ..Our study reflects the synergistic potential of the above combination and concludes that a multimodal approach could be beneficial rather than a singular intervention...
  14. doi request reprint Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion
    Ajmal Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, 110062, India
    Neurochem Res 36:1360-71. 2011
    ..Our study reveals that Q, as a powerful antioxidant, could prevent free radicals associated oxidative damage and morphological changes in the MCAO rats. Thus, it may have a therapeutic value for the treatment of stroke...
  15. doi request reprint Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: behavioral, neurochemical and immunohistochemical studies
    Gulrana Khuwaja
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Brain Res 1368:254-63. 2011
    ....
  16. doi request reprint Rutin protects the neural damage induced by transient focal ischemia in rats
    Mohd Moshahid Khan
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi, 110062, India
    Brain Res 1292:123-35. 2009
    ..Thus, rutin treatment may represent a novel approach in lowering the risk or improving the function of ischemia-reperfusion brain injury-related disorders...
  17. doi request reprint Synergistic effect of selenium and melatonin on neuroprotection in cerebral ischemia in rats
    Ajmal Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Biol Trace Elem Res 139:81-96. 2011
    ..In conclusion, we demonstrated that the pretreatment with Se-Mel at the onset of reperfusion, reduced post-ischemic damage, and improved neurological outcome following transient focal cerebral ischemia in male Wistar rat...
  18. doi request reprint Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model
    Pallavi Shrivastava
    Department of Medical Elementology and Toxicology DBT FIST and UGC SAP funded Department, Jamia Hamdard, Hamdard Nagar, New Delhi, India
    J Nutr Biochem 24:680-7. 2013
    ..We propose that, in addition to its antioxidant properties Piperine exerts a protective effect via anti-apoptotic and anti-inflammatory mechanism on 6-OHDA induced Parkinson's disease...
  19. ncbi request reprint Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences
    Muzamil Ahmad
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar New Delhi, India
    J Neurochem 93:94-104. 2005
    ..Considering our behavioural studies, biochemical analysis, and immunohistochemical observation, we conclude that EGb can be used as a therapeutic approach to check the neuronal loss following parkinsonism...
  20. ncbi request reprint Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus
    Seema Yousuf
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, New Delhi 110062, India
    Brain Res 1147:218-25. 2007
    ..The present study suggests that selenium may be able to salvage the ischemic penumbral zone neurons, thereby limiting ischemic cell death...
  21. doi request reprint Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model
    M Badruzzaman Khan
    Department of Medical Elementology and Toxicology, Hamdard University, Hamdard Nagar, New Delhi, India
    Neurochem Int 61:1081-93. 2012
    ..The study suggests that NAR can protect against cognitive deficits, neuronal injury and oxidative stress induced by ICV-STZ, and may be used as a potential agent in treatment of neurodegenerative diseases such as AD-TNDCI...
  22. ncbi request reprint Prevention of cognitive impairments and neurodegeneration by Khamira Abresham Hakim Arshad Wala
    M Badruzzaman Khan
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard Hamdard University, Hamdard Nagar, New Delhi 110062, India
    J Ethnopharmacol 108:68-73. 2006
    ..The study concludes that the therapeutic intervention of KAHAW may be used to prevent or to decrease the deterioration of cognitive function and neurobehavioral activities, often associated with the generation of free radicals...
  23. ncbi request reprint Selenium protects cerebral ischemia in rat brain mitochondria
    Mubeen Ahmad Ansari
    Neurotoxicology Laboratory, Department of Medical Elementology and Toxicology, Jamia Hamdard, Hamdard University, Hamdard Nagar, New Delhi 110062, India
    Biol Trace Elem Res 101:73-86. 2004
    ..It is concluded that selenium, which is an essential part of our diet, might be helpful in protection against neurodegeneration in cerebral ischemia...
  24. doi request reprint Modulatory effects of Pycnogenol in a rat model of insulin-dependent diabetes mellitus: biochemical, histological, and immunohistochemical evidences
    Kehkashan Parveen
    Department of Biochemistry, Lipid Metabolism Laboratory, Jamia Hamdard Hamdard University, New Delhi 110062, India
    Protoplasma 250:347-60. 2013
    ..The study suggests that PYC is effective in reducing diabetic-related complications in a type I model of diabetes and might be beneficial for the treatment of diabetic patients...