A Ischenko

Summary

Publications

  1. ncbi request reprint Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse
    J van Beek
    European Institute for Peptide Research IFRM P23, INSERM U519, Faculté Mixte de Médecine et de Pharmacie, Rouen Cedex, France
    Glia 31:39-50. 2000
  2. ncbi request reprint Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death
    J van Beek
    European Institute for Peptide Research IFRMP 23, INSERM U519, Rouen, France
    Neuroreport 12:289-93. 2001
  3. ncbi request reprint Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection
    Johan van Beek
    Brain Inflammation and Immunity Group, Department of Medical Biochemistry and Immunology, University of Wales College of Medicine, Cardiff, UK
    Ann N Y Acad Sci 992:56-71. 2003
  4. ncbi request reprint C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL-8
    T Monsinjon
    Faculté Mixte de Médecine Pharmacie, INSERM U519, Rouen, France
    FEBS Lett 487:339-46. 2001

Collaborators

  • P Gasque
  • J van Beek
  • M Fontaine
  • Johan van Beek
  • T Monsinjon
  • E T MacKenzie
  • Kristina Elward
  • A Buisson
  • C Ali
  • O Nicole
  • M Bernaudin
  • E Petit
  • P Chan

Detail Information

Publications4

  1. ncbi request reprint Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse
    J van Beek
    European Institute for Peptide Research IFRM P23, INSERM U519, Faculté Mixte de Médecine et de Pharmacie, Rouen Cedex, France
    Glia 31:39-50. 2000
    ..We conclude that local expression of complement components may contribute to the inflammation observed in this model, thereby representing an important process in secondary injury mechanisms after focal cerebral ischemia...
  2. ncbi request reprint Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death
    J van Beek
    European Institute for Peptide Research IFRMP 23, INSERM U519, Rouen, France
    Neuroreport 12:289-93. 2001
    ..These observations suggest that C3a is involved in excitotoxicity-mediated neuronal death through astrocyte stimulation and extend its role beyond immune functions...
  3. ncbi request reprint Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection
    Johan van Beek
    Brain Inflammation and Immunity Group, Department of Medical Biochemistry and Immunology, University of Wales College of Medicine, Cardiff, UK
    Ann N Y Acad Sci 992:56-71. 2003
    ..Because many effects of the complement appear to promote neuronal survival and tissue remodeling, directing activation of the complement system in the brain may provide a better therapeutic rationale than inhibiting it...
  4. ncbi request reprint C3A binds to the seven transmembrane anaphylatoxin receptor expressed by epithelial cells and triggers the production of IL-8
    T Monsinjon
    Faculté Mixte de Médecine Pharmacie, INSERM U519, Rouen, France
    FEBS Lett 487:339-46. 2001
    ..Pre-treatment of ECV 304 with pertussis toxin inhibited IL-8 response induced by C3a, indicating that the action of C3a was mediated by a G protein coupled pathway...