Mohammad Irshad

Summary

Publications

  1. ncbi request reprint HCV-genotypes: a review on their origin, global status, assay system, pathogenecity and response to treatment
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Hepatogastroenterology 57:1529-38. 2010
  2. pmc Cloning and expression of N22 region of Torque Teno virus (TTV) genome and use of peptide in developing immunoassay for TTV antibodies
    Dhananjay Singh Mankotia
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Virol J 11:96. 2014
  3. ncbi request reprint Apolipoproteins and their role in different clinical conditions: an overview
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Biochem Biophys 42:73-80. 2005
  4. ncbi request reprint Transfusion transmitted virus: A review on its molecular characteristics and role in medicine
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, PO Box 4938, A I I M S, New Delhi 110029, India
    World J Gastroenterol 12:5122-34. 2006
  5. ncbi request reprint Hepatitis C virus core protein: an update on its molecular biology, cellular functions and clinical implications
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Med Princ Pract 15:405-16. 2006
  6. ncbi request reprint Significance of hepatitis C virus core protein in the diagnosis of hepatitis C virus infection in different liver diseases
    Mohammad Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Investig Med 54:478-83. 2006
  7. ncbi request reprint Impact of viral hepatitis on apo- and lipoprotein status in blood
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Med Princ Pract 16:310-4. 2007
  8. ncbi request reprint Correlation of serum HCV core concentration with blood level of lipid and antioxidants in various forms of liver diseases
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Hepatogastroenterology 54:898-902. 2007
  9. pmc Torque teno virus: its prevalence and isotypes in North India
    Mohammad Irshad
    Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    World J Gastroenterol 14:6044-51. 2008
  10. ncbi request reprint Hepatitis C virus (HCV): a review of immunological aspects
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int Rev Immunol 27:497-517. 2008

Collaborators

Detail Information

Publications30

  1. ncbi request reprint HCV-genotypes: a review on their origin, global status, assay system, pathogenecity and response to treatment
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Hepatogastroenterology 57:1529-38. 2010
    ..In addition, these reports produce a further scope for more studies to unravel the mystery behind HCV-genotypes and formulate guidelines to resolve this public health problem noted worldwide...
  2. pmc Cloning and expression of N22 region of Torque Teno virus (TTV) genome and use of peptide in developing immunoassay for TTV antibodies
    Dhananjay Singh Mankotia
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Virol J 11:96. 2014
    ..Since TTV genotype-1 is more common in India, the serum positive for genotype-1 was used as source of N22 for expression purpose...
  3. ncbi request reprint Apolipoproteins and their role in different clinical conditions: an overview
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Biochem Biophys 42:73-80. 2005
    ..Present article gives an overview of the structural features, physiological significance and diagnostic and clinical implications of apolipoproteins...
  4. ncbi request reprint Transfusion transmitted virus: A review on its molecular characteristics and role in medicine
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, PO Box 4938, A I I M S, New Delhi 110029, India
    World J Gastroenterol 12:5122-34. 2006
    ..Recently, attempts have been made to eradicate this virus with interferon treatment. More information is still needed to extricate various mysteries related to TTV...
  5. ncbi request reprint Hepatitis C virus core protein: an update on its molecular biology, cellular functions and clinical implications
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Med Princ Pract 15:405-16. 2006
    ..Although published information shows a lot about the clinical significance of HCV core protein, several studies are still needed to demonstrate its exact significance in viral biology and underlying HCV pathogenesis...
  6. ncbi request reprint Significance of hepatitis C virus core protein in the diagnosis of hepatitis C virus infection in different liver diseases
    Mohammad Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Investig Med 54:478-83. 2006
    ..None of the control sera were positive for any hepatitis marker. The significance of HCV core protein in relation to HCV-RNA and anti-HCV for the diagnosis of HCV infection in different liver diseases has been discussed...
  7. ncbi request reprint Impact of viral hepatitis on apo- and lipoprotein status in blood
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Med Princ Pract 16:310-4. 2007
    ..To investigate the effect of viral hepatitis on serum levels of apo- and lipoproteins in different forms of liver diseases...
  8. ncbi request reprint Correlation of serum HCV core concentration with blood level of lipid and antioxidants in various forms of liver diseases
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Hepatogastroenterology 54:898-902. 2007
    ..The aim behind this study was to explore the possibility of HCV core induced lipid changes and ensuing oxidative liver damage in these liver diseases...
  9. pmc Torque teno virus: its prevalence and isotypes in North India
    Mohammad Irshad
    Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    World J Gastroenterol 14:6044-51. 2008
    ..To investigate the prevalence and genotype distribution of Torque teno virus (TTV) in patients with different liver diseases and chronic renal failure treated at a referral hospital in North India...
  10. ncbi request reprint Hepatitis C virus (HCV): a review of immunological aspects
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int Rev Immunol 27:497-517. 2008
    ..An effective immunotherapy and vaccine against HCV is still awaited...
  11. doi request reprint Torque teno virus infection in hemodialysis patients in North India
    Mohammad Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India
    Int Urol Nephrol 42:1077-83. 2010
    ..As such, this study concludes that TTV appears as a benign pathogen, showing no sign of renal/liver damage or any change in the severity of diseases caused by blood-borne hepatitis viruses...
  12. ncbi request reprint Transfusion-transmitted virus in association with hepatitis A-E viral infections in various forms of liver diseases in India
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, PO Box 4938, A I I M S, Ansari Nagar, New Delhi 110029, India
    World J Gastroenterol 12:2432-6. 2006
    ..To describe the prevalence of transfusion-transmitted virus (TTV) infection in association with hepatitis A-E viral infections in different forms of liver diseases in North India...
  13. ncbi request reprint Serum lipoprotein (a) levels in liver diseases caused by hepatitis
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Indian J Med Res 120:542-5. 2004
    ..The findings of this study suggested that serum Lp(a) level was significantly (P<0.001) reduced in patients with liver diseases irrespective of the viral etiology...
  14. pmc An insight into the diagnosis and pathogenesis of hepatitis C virus infection
    Mohammad Irshad
    Mohammad Irshad, Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    World J Gastroenterol 19:7896-909. 2013
    ..HCV pathogenesis is a very complex phenomenon and requires further study to determine the other factors involved. ..
  15. ncbi request reprint Novel single-step multiplex real-time polymerase chain reaction assay for simultaneous quantification of hepatitis virus A, B, C, and E in serum
    Mohammad Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Gastroenterol Hepatol 28:1869-76. 2013
    ....
  16. doi request reprint Expression of the full-length HCV core subgenome from HCV gentoype-1a and genotype-3a and evaluation of the antigenicity of translational products
    Mohammad A Ansari
    Department of Laboratory Medicine, Clinical Biochemistry Division, All India Institute of Medical Sciences, New Delhi, India
    Eur J Gastroenterol Hepatol 25:806-13. 2013
    ..Although commercial assays are available for the detection of both HCV RNA and genotypes, efforts aimed at the development of simple and economical systems for these measurements are still going on...
  17. doi request reprint Urinary potassium loss in children with acute liver failure and acute viral hepatitis
    Vidyut Bhatia
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
    J Pediatr Gastroenterol Nutr 57:102-8. 2013
    ....
  18. ncbi request reprint Prevalence of chronic renal failure in adults in Delhi, India
    Sanjay Kumar Agarwal
    Department of Nephrology, AIIMS, New Delhi 110029, India
    Nephrol Dial Transplant 20:1638-42. 2005
    ..Because of its costs and the complexity of its treatment, proper care is available to very few patients in India. A community-based study has not been done to determine the prevalence of CRF in India...
  19. ncbi request reprint Chronic hepatitis in a large Indian hospital
    S K Acharya
    All India Institute of Medical Sciences, Ansari Nagar, New Delhi
    Natl Med J India 6:202-6. 1993
    ..CONCLUSION. Chronic hepatitis is not uncommon in India. It presents with evidence of severe disease and, as elsewhere, is most frequently caused by the hepatitis B virus...
  20. ncbi request reprint Spectrum of viral hepatitis in thalassemic children receiving multiple blood transfusions
    Mohammad Irshad
    Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Gastroenterol 21:183-4. 2002
    ..To investigate the prevalence of infection with hepatitis viruses in children with thalassemia receiving multiple blood transfusions...
  21. ncbi request reprint Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats
    Yukti Sharma
    Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India
    Toxicology 206:49-57. 2005
    ..Erythrocyte acetylcholinesterase was inhibited at all doses used. Dose-dependent histopathological changes, observed in both liver and brain, are also described...
  22. ncbi request reprint Performance of Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), and PIM2 in a pediatric intensive care unit in a developing country
    Anu Thukral
    Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Pediatr Crit Care Med 7:356-61. 2006
    ..To determine the discriminative ability and calibration of existing scoring systems in predicting the outcome (mortality) in children admitted to an Indian pediatric intensive care unit (PICU)...
  23. ncbi request reprint Sero-epidemiology of hepatitis E virus (HEV) in urban and rural children of North India
    P Mathur
    Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Community Medicine and Laboratory Medicine, All India Institute of Medical Sciences, New Delhi - 110 029, India
    Indian Pediatr 38:461-75. 2001
    ..Seropositivity to HEV antibodies increased by over 2 times beyond 4 years of age as compared to younger age. Anti-HEV IgG antibodies appear to wean off with increasing age...
  24. ncbi request reprint Oxidative stress in liver diseases
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, AIIMS, New Delhi 110029, India
    Trop Gastroenterol 23:6-8. 2002
  25. ncbi request reprint Oxidant-antioxidant system: role and significance in human body
    M Irshad
    Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Exp Biol 40:1233-9. 2002
    ..As more and more reports are pouring in, a lot of information is being unfolded about oxidative stress in relation to several other diseases...
  26. ncbi request reprint Dimethoate-induced effects on antioxidant status of liver and brain of rats following subchronic exposure
    Yukti Sharma
    Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India
    Toxicology 215:173-81. 2005
    ....
  27. pmc Comparison of nebulised magnesium sulphate and salbutamol combined with salbutamol alone in the treatment of acute bronchial asthma: a randomised study
    P Aggarwal
    Department of Emergency Medicine, All India Institute of Medical Sciences, New Delhi, India
    Emerg Med J 23:358-62. 2006
    ..To test the hypothesis that combined administration of multiple doses of nebulised salbutamol and magnesium sulphate provides additional benefit compared with salbutamol alone in adult patients with acute asthma...
  28. ncbi request reprint Hepatitis B immunization in low birthweight infants: do they need an additional dose?
    N K Arora
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi
    Acta Paediatr 91:995-1001. 2002
    ..To determine the influence of gestation and weight on the development of protective anti-HB levels and geometric mean titres after three doses of HBV vaccine and to ascertain the need for a fourth dose in low birthweight infants...
  29. ncbi request reprint Arsenic induced apoptosis in rat liver following repeated 60 days exposure
    Somia Bashir
    Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences AIIMS, New Delhi 110029, India
    Toxicology 217:63-70. 2006
    ..Exposure to arsenite and other arsenicals has been previously shown to induce apoptosis in certain tumor cell lines at low (1-3 microM) concentration...
  30. ncbi request reprint Prevalence of hepatitis B virus infection in healthy persons in North India
    M Irshad
    Department of Laboratory Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
    Natl Med J India 7:210-2. 1994
    ..6%). CONCLUSIONS. Our results indicate that in India the so-called high risk groups, other than truck drivers and professional blood donors, are unlikely to represent major sources of infection...