HCV-genotypes: a review on their origin, global status, assay system, pathogenecity and response to treatmentM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Hepatogastroenterology 57:1529-38. 2010
..In addition, these reports produce a further scope for more studies to unravel the mystery behind HCV-genotypes and formulate guidelines to resolve this public health problem noted worldwide...
Impact of viral hepatitis on apo- and lipoprotein status in bloodM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
Med Princ Pract 16:310-4. 2007
..To investigate the effect of viral hepatitis on serum levels of apo- and lipoproteins in different forms of liver diseases...
Significance of hepatitis C virus core protein in the diagnosis of hepatitis C virus infection in different liver diseasesMohammad Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
J Investig Med 54:478-83. 2006
..None of the control sera were positive for any hepatitis marker. The significance of HCV core protein in relation to HCV-RNA and anti-HCV for the diagnosis of HCV infection in different liver diseases has been discussed...
Hepatitis C virus core protein: an update on its molecular biology, cellular functions and clinical implicationsM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
Med Princ Pract 15:405-16. 2006
..Although published information shows a lot about the clinical significance of HCV core protein, several studies are still needed to demonstrate its exact significance in viral biology and underlying HCV pathogenesis...
Transfusion transmitted virus: A review on its molecular characteristics and role in medicineM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, PO Box 4938, A I I M S, New Delhi 110029, India
World J Gastroenterol 12:5122-34. 2006
..Recently, attempts have been made to eradicate this virus with interferon treatment. More information is still needed to extricate various mysteries related to TTV...
Transfusion-transmitted virus in association with hepatitis A-E viral infections in various forms of liver diseases in IndiaM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, PO Box 4938, A I I M S, Ansari Nagar, New Delhi 110029, India
World J Gastroenterol 12:2432-6. 2006
..To describe the prevalence of transfusion-transmitted virus (TTV) infection in association with hepatitis A-E viral infections in different forms of liver diseases in North India...
Torque teno virus: its prevalence and isotypes in North IndiaMohammad Irshad
Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
World J Gastroenterol 14:6044-51. 2008
..To investigate the prevalence and genotype distribution of Torque teno virus (TTV) in patients with different liver diseases and chronic renal failure treated at a referral hospital in North India...
Hepatitis C virus (HCV): a review of immunological aspectsM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
Int Rev Immunol 27:497-517. 2008
..An effective immunotherapy and vaccine against HCV is still awaited...
Correlation of serum HCV core concentration with blood level of lipid and antioxidants in various forms of liver diseasesM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
Hepatogastroenterology 54:898-902. 2007
..The aim behind this study was to explore the possibility of HCV core induced lipid changes and ensuing oxidative liver damage in these liver diseases...
Serum lipoprotein (a) levels in liver diseases caused by hepatitisM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Indian J Med Res 120:542-5. 2004
..The findings of this study suggested that serum Lp(a) level was significantly (P<0.001) reduced in patients with liver diseases irrespective of the viral etiology...
Torque teno virus infection in hemodialysis patients in North IndiaMohammad Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India
Int Urol Nephrol 42:1077-83. 2010
..As such, this study concludes that TTV appears as a benign pathogen, showing no sign of renal/liver damage or any change in the severity of diseases caused by blood-borne hepatitis viruses...
Prevalence of chronic renal failure in adults in Delhi, IndiaSanjay Kumar Agarwal
Department of Nephrology, AIIMS, New Delhi 110029, India
Nephrol Dial Transplant 20:1638-42. 2005
..Because of its costs and the complexity of its treatment, proper care is available to very few patients in India. A community-based study has not been done to determine the prevalence of CRF in India...
Chronic hepatitis in a large Indian hospitalS K Acharya
All India Institute of Medical Sciences, Ansari Nagar, New Delhi
Natl Med J India 6:202-6. 1993
..CONCLUSION. Chronic hepatitis is not uncommon in India. It presents with evidence of severe disease and, as elsewhere, is most frequently caused by the hepatitis B virus...
Spectrum of viral hepatitis in thalassemic children receiving multiple blood transfusionsMohammad Irshad
Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi
Indian J Gastroenterol 21:183-4. 2002
..CONCLUSION: Thalassemic patients receiving multiple blood transfusions often acquire hepatitis B (20%) and C (30%) infections. Recent hepatitis E infection was documented in 10% in this one-point study...
Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental ratsYukti Sharma
Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India
Toxicology 206:49-57. 2005
..Erythrocyte acetylcholinesterase was inhibited at all doses used. Dose-dependent histopathological changes, observed in both liver and brain, are also described...
Performance of Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), and PIM2 in a pediatric intensive care unit in a developing countryAnu Thukral
Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Pediatr Crit Care Med 7:356-61. 2006
..The likely reasons for this could be differences in the patient profile and greater load of severity of illness being managed with lesser resources--both physical and human--and differences in the quality of care...
Oxidative stress in liver diseasesM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, AIIMS, New Delhi 110029, India
Trop Gastroenterol 23:6-8. 2002
Sero-epidemiology of hepatitis E virus (HEV) in urban and rural children of North IndiaP Mathur
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Community Medicine and Laboratory Medicine, All India Institute of Medical Sciences, New Delhi - 110 029, India
Indian Pediatr 38:461-75. 2001
..Seropositivity to HEV antibodies increased by over 2 times beyond 4 years of age as compared to younger age. Anti-HEV IgG antibodies appear to wean off with increasing age...
Oxidant-antioxidant system: role and significance in human bodyM Irshad
Clinical Biochemistry Division, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Indian J Exp Biol 40:1233-9. 2002
..As more and more reports are pouring in, a lot of information is being unfolded about oxidative stress in relation to several other diseases...
Dimethoate-induced effects on antioxidant status of liver and brain of rats following subchronic exposureYukti Sharma
Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India
Toxicology 215:173-81. 2005
....
Comparison of nebulised magnesium sulphate and salbutamol combined with salbutamol alone in the treatment of acute bronchial asthma: a randomised studyP Aggarwal
Department of Emergency Medicine, All India Institute of Medical Sciences, New Delhi, India
Emerg Med J 23:358-62. 2006
..To test the hypothesis that combined administration of multiple doses of nebulised salbutamol and magnesium sulphate provides additional benefit compared with salbutamol alone in adult patients with acute asthma...
Arsenic induced apoptosis in rat liver following repeated 60 days exposureSomia Bashir
Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences AIIMS, New Delhi 110029, India
Toxicology 217:63-70. 2006
..Exposure to arsenite and other arsenicals has been previously shown to induce apoptosis in certain tumor cell lines at low (1-3 microM) concentration...
Hepatitis B immunization in low birthweight infants: do they need an additional dose?N K Arora
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi
Acta Paediatr 91:995-1001. 2002
..To determine the influence of gestation and weight on the development of protective anti-HB levels and geometric mean titres after three doses of HBV vaccine and to ascertain the need for a fourth dose in low birthweight infants...
Prevalence of hepatitis B virus infection in healthy persons in North IndiaM Irshad
Department of Laboratory Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
Natl Med J India 7:210-2. 1994
..6%). CONCLUSIONS. Our results indicate that in India the so-called high risk groups, other than truck drivers and professional blood donors, are unlikely to represent major sources of infection...