John M Nolan

Summary

Affiliation: Waterford Institute of Technology
Country: Ireland

Publications

  1. pmc Macular pigment and its contribution to vision
    Ekaterina Loskutova
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Nutrients 5:1962-9. 2013
  2. pmc What is meso-zeaxanthin, and where does it come from?
    J M Nolan
    Macular Pigment Research Group, Vision Research Centre, Carriganore House, Waterford Institute of Technology, Waterford, Ireland
    Eye (Lond) 27:899-905. 2013
  3. doi request reprint Education is positively associated with macular pigment: the Irish Longitudinal Study on Ageing (TILDA)
    John M Nolan
    Macular Pigment Research Group in the Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 53:7855-61. 2012
  4. doi request reprint Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Exp Eye Res 101:9-15. 2012
  5. doi request reprint The impact of macular pigment augmentation on visual performance in normal subjects: COMPASS
    John M Nolan
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Vision Res 51:459-69. 2011
  6. doi request reprint A central dip in the macular pigment spatial profile is associated with age and smoking
    Mark L Kirby
    Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 51:6722-8. 2010
  7. doi request reprint Augmentation of macular pigment following implantation of blue light-filtering intraocular lenses at the time of cataract surgery
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 50:4777-85. 2009
  8. doi request reprint Macular pigment optical density in an ageing Irish population: The Irish Longitudinal Study on Ageing
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, and Institute of Vision Research, Whitfield Clinic, Waterford, Ireland jmnolan wit ie
    Ophthalmic Res 44:131-9. 2010
  9. doi request reprint Augmentation of macular pigment following supplementation with all three macular carotenoids: an exploratory study
    Eithne E Connolly
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Curr Eye Res 35:335-51. 2010
  10. doi request reprint Apolipoprotein E genotype is associated with macular pigment optical density
    Edward Loane
    Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 51:2636-43. 2010

Detail Information

Publications30

  1. pmc Macular pigment and its contribution to vision
    Ekaterina Loskutova
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Nutrients 5:1962-9. 2013
    ..Supplementation with L, Z and MZ augments MP and enhances visual performance in diseased and non-diseased eyes, and may reduce risk of AMD development and/or progression...
  2. pmc What is meso-zeaxanthin, and where does it come from?
    J M Nolan
    Macular Pigment Research Group, Vision Research Centre, Carriganore House, Waterford Institute of Technology, Waterford, Ireland
    Eye (Lond) 27:899-905. 2013
    ..Certainly, the narrative that retinal MZ is derived wholly and solely from retinal L needs to be revisited. ..
  3. doi request reprint Education is positively associated with macular pigment: the Irish Longitudinal Study on Ageing (TILDA)
    John M Nolan
    Macular Pigment Research Group in the Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 53:7855-61. 2012
    ..This study was undertaken to investigate determinants of MP in a large randomly selected sample from the Republic of Ireland (as part of The Irish Longitudinal Study on Ageing [TILDA])...
  4. doi request reprint Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Exp Eye Res 101:9-15. 2012
    ..The implications of our findings, in terms of visual performance and/or a (photo)-protective effect, warrant additional study...
  5. doi request reprint The impact of macular pigment augmentation on visual performance in normal subjects: COMPASS
    John M Nolan
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Vision Res 51:459-69. 2011
    ..05) Further study into the relationship between MP and VP is warranted, with particular attention directed towards individuals with low MP and suboptimal VP...
  6. doi request reprint A central dip in the macular pigment spatial profile is associated with age and smoking
    Mark L Kirby
    Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 51:6722-8. 2010
    ..To investigate the relationship between specific macular pigment (MP) spatial profiles and risk factors for age-related macular degeneration (AMD)...
  7. doi request reprint Augmentation of macular pigment following implantation of blue light-filtering intraocular lenses at the time of cataract surgery
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 50:4777-85. 2009
    ..This study was designed to investigate whether the blue light-filtering properties of the Alcon AcrySof Natural intraocular lens (ANIOL) implanted during cataract surgery affects MP optical density (MPOD)...
  8. doi request reprint Macular pigment optical density in an ageing Irish population: The Irish Longitudinal Study on Ageing
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, and Institute of Vision Research, Whitfield Clinic, Waterford, Ireland jmnolan wit ie
    Ophthalmic Res 44:131-9. 2010
    ..This study was undertaken to compare MP optical density (MPOD) in a population aged > or =50 years with MPOD values from a normative database of subjects aged 18-60 years...
  9. doi request reprint Augmentation of macular pigment following supplementation with all three macular carotenoids: an exploratory study
    Eithne E Connolly
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Curr Eye Res 35:335-51. 2010
    ..At the macula, the carotenoids meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z) are collectively referred to as macular pigment (MP). This study was designed to measure serum and macular responses to a macular carotenoid formulation...
  10. doi request reprint Apolipoprotein E genotype is associated with macular pigment optical density
    Edward Loane
    Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 51:2636-43. 2010
    ..This study was designed to investigate the relationship between macular pigment optical density (MPOD) and ApoE genotype...
  11. doi request reprint The association between macular pigment optical density and CFH, ARMS2, C2/BF, and C3 genotype
    Edward Loane
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Exp Eye Res 93:592-8. 2011
    ..These findings suggest that the maculae of subjects at very high genetic risk of AMD represent a hostile environment for accumulation and/or stabilization of MP...
  12. doi request reprint Supplementation with all three macular carotenoids: response, stability, and safety
    Eithne E Connolly
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 52:9207-17. 2011
    ..This study was designed to investigate serum and macular response to, and safety of supplementation with, meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z), the carotenoids that constitute macular pigment (MP)...
  13. ncbi request reprint The relationships between macular pigment optical density and its constituent carotenoids in diet and serum
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Cork Road, Waterford, Ireland
    Invest Ophthalmol Vis Sci 48:571-82. 2007
    ..This study was undertaken to investigate the relationship between dietary intake of L and Z, serum concentrations of these carotenoids, and MP optical density in 828 healthy Irish subjects...
  14. doi request reprint The relationship between macular pigment and visual performance
    James Loughman
    Macular Pigment Research Group, Optometry Department, Dublin Institute of Technology, Dublin, Ireland
    Vision Res 50:1249-56. 2010
    ..05). A longitudinal, placebo-controlled and randomized supplementation trial will be required to ascertain whether augmentation of MPOD can influence visual performance...
  15. doi request reprint Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration
    Katherine A Meagher
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Republic of Ireland
    Br J Nutr 110:289-300. 2013
    ....
  16. doi request reprint An evaluation of a novel instrument for measuring macular pigment optical density: the MPS 9000
    James Loughman
    Macular Pigment Research Group, Dublin Institute of Technology, Optometry Department, College of Sciences and Health, Dublin 8, Ireland
    Acta Ophthalmol 90:e90-7. 2012
    ..Also, we assessed and compared test-retest variability for each instrument...
  17. doi request reprint A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration
    Sarah Sabour-Pickett
    Department of Optometry, College of Sciences and Health, Dublin Institute of Technology, Dublin, Ireland
    Mol Nutr Food Res 56:270-86. 2012
    ....
  18. doi request reprint The respective relationships between lipoprotein profile, macular pigment optical density, and serum concentrations of lutein and zeaxanthin
    Edward Loane
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 51:5897-905. 2010
    ..This study was an investigation of the respective relationships between serum lipoprotein profile, MP optical density (MPOD), and serum L and Z...
  19. doi request reprint Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance
    Jessica L Dennison
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Carriganore House, W I T West Campus, Carriganore, Waterford, Ireland Electronic address
    Exp Eye Res 116:190-8. 2013
    ..Taking cHFP as the current standard to which other MP measuring devices should be compared, the Spectralis is suitable for use in a clinical and research setting, whereas the Visucam is not. ..
  20. doi request reprint Secondary outcomes in a clinical trial of carotenoids with coantioxidants versus placebo in early age-related macular degeneration
    Stephen Beatty
    Macular Pigment Research Group, Waterford Institute of Technology, Waterford City, Waterford, Republic of Ireland
    Ophthalmology 120:600-6. 2013
    ..To report the secondary outcomes in the Carotenoids with Coantioxidants in Age-Related Maculopathy trial...
  21. doi request reprint Transport and retinal capture of lutein and zeaxanthin with reference to age-related macular degeneration
    Edward Loane
    Macular Pigment Research Group, Waterford Institute of Technology, Waterford, Ireland
    Surv Ophthalmol 53:68-81. 2008
    ..This article reviews the literature germane to the mechanisms involved in the capture, accumulation and stabilization of lutein and zeaxanthin by the retina, and the processes involved in their transport in serum...
  22. ncbi request reprint Measurement of macular pigment optical density using two different heterochromatic flicker photometers
    Edward Loane
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Curr Eye Res 32:555-64. 2007
    ..To compare macular pigment optical density using two different heterochromatic flicker photometers...
  23. ncbi request reprint Diet and risk factors for age-related maculopathy
    Eamonn D O'Connell
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Am J Clin Nutr 87:712-22. 2008
    ..Evidence continues to accumulate that oxidative stress is etiologically important in the pathogenesis of age-related maculopathy (ARM) and that appropriate antioxidants of dietary origin may protect against this condition...
  24. ncbi request reprint Risk factors for age-related maculopathy are associated with a relative lack of macular pigment
    John M Nolan
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Cork Road, Waterford, Ireland
    Exp Eye Res 84:61-74. 2007
    ....
  25. doi request reprint Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss
    Mark L Kirby
    Macular Pigment Research Group, Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Republic of Ireland
    Br J Nutr 105:1036-46. 2011
    ..g. fat mass) is related to increases in serum concentrations of L is consistent with the hypothesis that body fat acts as a reservoir for this carotenoid, and that weight loss can positively influence circulating carotenoid levels...
  26. doi request reprint Foveal anatomic associations with the secondary peak and the slope of the macular pigment spatial profile
    Mark L Kirby
    Department of Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
    Invest Ophthalmol Vis Sci 50:1383-91. 2009
    ..To investigate the reproducibility of the macular pigment (MP) spatial profile by using heterochromatic flicker photometry (HFP) and to relate the MP spatial profile to foveal architecture...
  27. ncbi request reprint Monthly consistency of macular pigment optical density and serum concentrations of lutein and zeaxanthin
    John M Nolan
    Macular Pigment Research Laboratory, Department of Chemical and Life Sciences, Waterford Institute of Technology, and Department of Ophthalmology, Waterford Regional Hospital, Ireland
    Curr Eye Res 31:199-213. 2006
    ..Four healthy subjects aged between 23 and 51 years volunteered to participate in this study...
  28. doi request reprint Spatial profile of macular pigment and its relationship to foveal architecture
    John M Nolan
    Department of Ophthalmology, Medical College of Georgia, Augusta, GA, USA
    Invest Ophthalmol Vis Sci 49:2134-42. 2008
    ..This study is an initial investigation of the relationship between the spatial profile of macular pigment and foveal architecture...
  29. pmc Visual performance in patients with neovascular age-related macular degeneration undergoing treatment with intravitreal ranibizumab
    Sarah Sabour-Pickett
    Department of Optometry, School of Physics, Dublin Institute of Technology, Dublin, Ireland Institute of Eye Surgery and Institute of Vision Research, Whitfield Clinic, Waterford, Ireland Macular Pigment Research Group, Waterford Institute of Technology, Waterford, Ireland
    J Ophthalmol 2013:268438. 2013
    ..Outcome measures other than CDVA, such as CS, GD, and ROS, should not only be considered in the design of studies investigating nv-AMD, but also in treatment and retreatment strategies for patients with the condition...
  30. pmc Risk factors for age-related maculopathy
    Paul P Connell
    Waterford Regional Hospital, Dunmore Road, Waterford, Ireland
    J Ophthalmol 2009:360764. 2009
    ....