Amanda J O'Neill

Summary

Affiliation: University College Dublin
Country: Ireland

Publications

  1. pmc Characterisation and manipulation of docetaxel resistant prostate cancer cell lines
    Amanda J O'Neill
    UCD School of Medicine and Medical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
    Mol Cancer 10:126. 2011
  2. ncbi request reprint Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland
    Pediatr Res 56:99-103. 2004
  3. ncbi request reprint Sex-specific alterations in neutrophil apoptosis: the role of estradiol and progesterone
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, Dublin, Ireland
    Blood 102:2653-9. 2003
  4. ncbi request reprint Labor induces a maternal inflammatory response syndrome
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland
    Am J Obstet Gynecol 190:448-55. 2004
  5. ncbi request reprint Inhibitors of apoptosis proteins in prostate cancer cell lines
    Kevin R McEleny
    Department of Surgery, Mater Misericordiae Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, 47 Eccles Street, Dublin 7, Ireland
    Prostate 51:133-40. 2002
  6. ncbi request reprint Endothelin in unilateral ureteral obstruction: vascular and cellular effects
    Nicholas J Hegarty
    Department of Surgery, Mater Misericordiae Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
    J Urol 169:740-4. 2003
  7. ncbi request reprint Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis
    Amanda J O'Neill
    Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Shock 21:512-8. 2004
  8. ncbi request reprint Cytoprotective effects of nitrates in a cellular model of hydronephrosis
    Nicholas J Hegarty
    Department of Surgery, Mater Misericordiae Hospital, University College Dublin, 47 Eccles Street, Dublin 7, Ireland
    Kidney Int 62:70-7. 2002
  9. ncbi request reprint Aspirin preserves neutrophil apoptosis after cardiopulmonary bypass
    John J Bates
    Department of Anaesthesia and Intensive Care Medicine, Mater Misericordiae University Hospital, Dublin, Ireland
    Shock 21:495-9. 2004
  10. pmc Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
    Catherine Gill
    UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
    Mol Cancer 8:39. 2009

Collaborators

Detail Information

Publications11

  1. pmc Characterisation and manipulation of docetaxel resistant prostate cancer cell lines
    Amanda J O'Neill
    UCD School of Medicine and Medical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
    Mol Cancer 10:126. 2011
    ..Three Docetaxel resistant sub-lines were generated and confirmed to be resistant to the apoptotic and anti-proliferative effects of increasing concentrations of Docetaxel...
  2. ncbi request reprint Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland
    Pediatr Res 56:99-103. 2004
    ..Neonatal neutrophil survival and function are altered by labor and may increase antibacterial function and neutrophilia. This suggests that labor of any duration may be immunologically beneficial to the normal term neonate...
  3. ncbi request reprint Sex-specific alterations in neutrophil apoptosis: the role of estradiol and progesterone
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, Dublin, Ireland
    Blood 102:2653-9. 2003
    ..Thus, female sex hormones mediate delayed neutrophil apoptosis in both sexes and enhance female intracellular production of ROIs. Modulating hormonal responses may be an effective therapeutic tool in combating inflammatory diseases...
  4. ncbi request reprint Labor induces a maternal inflammatory response syndrome
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland
    Am J Obstet Gynecol 190:448-55. 2004
    ..We studied the effect of labor on maternal neutrophil phenotype...
  5. ncbi request reprint Inhibitors of apoptosis proteins in prostate cancer cell lines
    Kevin R McEleny
    Department of Surgery, Mater Misericordiae Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, 47 Eccles Street, Dublin 7, Ireland
    Prostate 51:133-40. 2002
    ..The inhibitors of apoptosis proteins (IAPs) are a family of recently described caspase inhibitors. We hypothesised that tumor resistance to apoptosis could be due in part to IAP expression...
  6. ncbi request reprint Endothelin in unilateral ureteral obstruction: vascular and cellular effects
    Nicholas J Hegarty
    Department of Surgery, Mater Misericordiae Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
    J Urol 169:740-4. 2003
    ..We explored the role of endothelin and the effects of endothelin receptor blockade in unilateral ureteral obstruction...
  7. ncbi request reprint Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis
    Amanda J O'Neill
    Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Shock 21:512-8. 2004
    ....
  8. ncbi request reprint Cytoprotective effects of nitrates in a cellular model of hydronephrosis
    Nicholas J Hegarty
    Department of Surgery, Mater Misericordiae Hospital, University College Dublin, 47 Eccles Street, Dublin 7, Ireland
    Kidney Int 62:70-7. 2002
    ..Nitric oxide (NO) has been shown to protect against renal injury in UO, but its mode of action has not been clearly defined...
  9. ncbi request reprint Aspirin preserves neutrophil apoptosis after cardiopulmonary bypass
    John J Bates
    Department of Anaesthesia and Intensive Care Medicine, Mater Misericordiae University Hospital, Dublin, Ireland
    Shock 21:495-9. 2004
    ..This was associated with greater inhibition of PGE2, consistent with the hypothesis that aspirin exerts its effect on apoptosis after CPB via a cyclooxygenase-mediated mechanism...
  10. pmc Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
    Catherine Gill
    UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
    Mol Cancer 8:39. 2009
    ..We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockdown of cIAP-1, cIAP-2 and XIAP would increase sensitivity to apoptosis...
  11. ncbi request reprint Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis
    Eleanor J Molloy
    Department of Surgery, Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Am J Perinatol 24:525-30. 2007
    ..Infants with mild encephalopathy may display a predominantly proinflammatory neutrophil response with a persistent inflammatory response, whereas those with moderate/severe encephalopathy have a tendency toward immunosuppression...