J E Nally

Summary

Affiliation: University College Dublin
Country: Ireland

Publications

  1. pmc Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection
    Jarlath E Nally
    Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Infect Immun 75:766-73. 2007
  2. pmc Comparative proteomic analysis of differentially expressed proteins in the urine of reservoir hosts of leptospirosis
    Jarlath E Nally
    Veterinary Science Centre, UCD School of Agriculture Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin, Republic of Ireland
    PLoS ONE 6:e26046. 2011
  3. doi Proteomic strategies to elucidate pathogenic mechanisms of spirochetes
    Jarlath E Nally
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Ireland
    Proteomics Clin Appl 1:1185-97. 2007
  4. doi Detection of Toxoplasma gondii antigens reactive with antibodies from serum, amniotic, and allantoic fluids from experimentally infected pregnant ewes
    P X Marques
    School of Agriculture, Food Science and Veterinary Medicine, Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Parasitol 185:91-100. 2012
  5. pmc Identification of immunologically relevant proteins of Chlamydophila abortus using sera from experimentally infected pregnant ewes
    P X Marques
    UCD School of Agriculture Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Clin Vaccine Immunol 17:1274-81. 2010
  6. doi Interferon-γ expression in trophoblast cells in pregnant ewes challenged with Chlamydophila abortus
    S Worrall
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    J Reprod Immunol 90:214-9. 2011
  7. doi Detection and quantification of leptospires in urine of dogs: a maintenance host for the zoonotic disease leptospirosis
    P Rojas
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Eur J Clin Microbiol Infect Dis 29:1305-9. 2010
  8. pmc Identification of spirochetes associated with contagious ovine digital dermatitis
    G Sayers
    Veterinary Sciences Centre, School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin, Ireland
    J Clin Microbiol 47:1199-201. 2009
  9. pmc Proteomic analysis of Leptospira interrogans shed in urine of chronically infected hosts
    Avril M Monahan
    Veterinary Sciences Centre, UCD School of Agriculture Food Science and Veterinary Medicine, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    Infect Immun 76:4952-8. 2008
  10. doi Review paper: Host-pathogen interactions in the kidney during chronic leptospirosis
    A M Monahan
    Veterinary Sciences Centre, UCD School of Agriculture Food Science and Veterinary Medicine, UCD Conway Institute of Biomolecular and Biomedical Research, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Pathol 46:792-9. 2009

Collaborators

Detail Information

Publications18

  1. pmc Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection
    Jarlath E Nally
    Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Infect Immun 75:766-73. 2007
    ..Significant amounts of LipL32 are also expressed by Leptospira during acute infection of guinea pigs...
  2. pmc Comparative proteomic analysis of differentially expressed proteins in the urine of reservoir hosts of leptospirosis
    Jarlath E Nally
    Veterinary Science Centre, UCD School of Agriculture Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin, Republic of Ireland
    PLoS ONE 6:e26046. 2011
    ..Results confirm differential protein expression by both host and pathogen during chronic disease and include markers of kidney function and immunoglobulin which are potential biomarkers of infection...
  3. doi Proteomic strategies to elucidate pathogenic mechanisms of spirochetes
    Jarlath E Nally
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Ireland
    Proteomics Clin Appl 1:1185-97. 2007
    ..Characterization of the proteome in response to such signals provides novel insights to understand pathogenic mechanisms of spirochetes...
  4. doi Detection of Toxoplasma gondii antigens reactive with antibodies from serum, amniotic, and allantoic fluids from experimentally infected pregnant ewes
    P X Marques
    School of Agriculture, Food Science and Veterinary Medicine, Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Parasitol 185:91-100. 2012
    ....
  5. pmc Identification of immunologically relevant proteins of Chlamydophila abortus using sera from experimentally infected pregnant ewes
    P X Marques
    UCD School of Agriculture Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Clin Vaccine Immunol 17:1274-81. 2010
    ....
  6. doi Interferon-γ expression in trophoblast cells in pregnant ewes challenged with Chlamydophila abortus
    S Worrall
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    J Reprod Immunol 90:214-9. 2011
    ....
  7. doi Detection and quantification of leptospires in urine of dogs: a maintenance host for the zoonotic disease leptospirosis
    P Rojas
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Eur J Clin Microbiol Infect Dis 29:1305-9. 2010
    ..05%. These results highlight the need to provide effective canine vaccination strategies and raise public health awareness...
  8. pmc Identification of spirochetes associated with contagious ovine digital dermatitis
    G Sayers
    Veterinary Sciences Centre, School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin, Ireland
    J Clin Microbiol 47:1199-201. 2009
    ....
  9. pmc Proteomic analysis of Leptospira interrogans shed in urine of chronically infected hosts
    Avril M Monahan
    Veterinary Sciences Centre, UCD School of Agriculture Food Science and Veterinary Medicine, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    Infect Immun 76:4952-8. 2008
    ..Results confirm that differential protein expression by Leptospira during chronic infection facilitates its persistence in the presence of a specific host antibody response...
  10. doi Review paper: Host-pathogen interactions in the kidney during chronic leptospirosis
    A M Monahan
    Veterinary Sciences Centre, UCD School of Agriculture Food Science and Veterinary Medicine, UCD Conway Institute of Biomolecular and Biomedical Research, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Pathol 46:792-9. 2009
    ....
  11. doi Leptospirosis: risks during recreational activities
    A M Monahan
    Veterinary Sciences Center, UCD School of Agriculture Food Science and Veterinary Medicine, UCD Conway Institute of Biomolecular and Biomedical Research, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
    J Appl Microbiol 107:707-16. 2009
    ..Molecular techniques can be used to provide risk assessments prior to competition, to supplement epidemiology, and to assess shedding of Leptospira in urine samples...
  12. pmc Changes in lipopolysaccharide O antigen distinguish acute versus chronic Leptospira interrogans infections
    Jarlath E Nally
    Department of Medicine, 37 121 CHS, Division of Infectious Diseases, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
    Infect Immun 73:3251-60. 2005
    ..The hypothesis that the Oag content is related to whether lethal infection or chronic renal tubular colonization occurs remains to be tested...
  13. pmc Alveolar septal deposition of immunoglobulin and complement parallels pulmonary hemorrhage in a guinea pig model of severe pulmonary leptospirosis
    Jarlath E Nally
    Division of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    Am J Pathol 164:1115-27. 2004
    ..This suggests that an autoimmune process may be the etiology of fatal pulmonary hemorrhage in leptospirosis...
  14. doi Detection and quantification of Toxoplasma gondii in ovine maternal and foetal tissues from experimentally infected pregnant ewes using real-time PCR
    J Gutierrez
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
    Vet Parasitol 172:8-15. 2010
    ..These results indicate that the cotyledonary component of the foetal membranes is the sample of choice for the diagnosis of T. gondii by rt-PCR, followed by foetal lung and brain...
  15. doi Analysis of bacterial membrane proteins produced during mammalian infection using hydrophobic antigen tissue triton extraction (HATTREX)
    Timothy R Crother
    Pediatrics Infectious Diseases, Cedars Sinai Medical Center, University of California, Los Angeles, California, USA
    Curr Protoc Microbiol . 2008
    ..Characterization of the detergent phase sample provides insights into the proteome of bacterial membranes during infection...
  16. pmc Lethal infection of C3H/HeJ and C3H/SCID mice with an isolate of Leptospira interrogans serovar copenhageni
    Jarlath E Nally
    Department of Medicine, Division of Infectious Diseases, University of California Los Angeles, 90095, USA
    Infect Immun 73:7014-7. 2005
    ..In this study, RJ16441 caused lethal infection of both C3H/HeJ and C3H/SCID mice, but no hemorrhagic phenomena were observed...
  17. ncbi Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni
    Jarlath E Nally
    Division of Infectious Diseases, Department of Medicine, University of California, Los Angeles, CA 90095, USA
    Proteomics 5:144-52. 2005
    ....
  18. ncbi Leptospirosis: a zoonotic disease of global importance
    Ajay R Bharti
    Division of Infectious Diseases, Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA 92093, USA
    Lancet Infect Dis 3:757-71. 2003
    ..Mainstays of treatment are still tetracyclines and beta-lactam/cephalosporins. No vaccine is available. Prevention is largely dependent on sanitation measures that may be difficult to implement, especially in developing countries...