Seamus Giles

Summary

Affiliation: University College Dublin
Country: Ireland

Publications

  1. ncbi request reprint The effects of ethanol on CNS development in the chick embryo
    Seamus Giles
    School of Medicine and Medical Science, Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
    Reprod Toxicol 25:224-30. 2008
  2. ncbi request reprint Ocular involvement in fetal alcohol spectrum disorder: a review
    Deirdre Brennan
    School of Medicine and Medical Science, Health Sciences Building, University College Dublin, Belfield, Donnybrook, Dublin 4 Ireland
    Curr Pharm Des 20:5377-87. 2014
  3. ncbi request reprint Teratogenic and developmental effects of lithium
    James J Giles
    Department of Human Anatomy and Physiology and Conway Institute of Biomolecular and Biomedical Research, National University of Ireland, Dublin, Ireland
    Curr Pharm Des 12:1531-41. 2006
  4. ncbi request reprint Sonic hedgehog expression is disrupted following in ovo ethanol exposure during early chick eye development
    Deirdre Brennan
    School of Medicine and Medical Science, University College Dublin, Belfield, Ireland
    Reprod Toxicol 41:49-56. 2013
  5. ncbi request reprint Histological characterisation of the ethanol-induced microphthalmia phenotype in a chick embryo model system
    Kevin Kennelly
    School of Medicine and Medical Science, Health Sciences Building, University College Dublin, Belfield, Dublin 4, Ireland
    Reprod Toxicol 32:227-34. 2011

Collaborators

Detail Information

Publications5

  1. ncbi request reprint The effects of ethanol on CNS development in the chick embryo
    Seamus Giles
    School of Medicine and Medical Science, Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
    Reprod Toxicol 25:224-30. 2008
    ..No gross malformations were observed. We conclude that these results further highlight the stage-specific effects of ethanol on neurodevelopment...
  2. ncbi request reprint Ocular involvement in fetal alcohol spectrum disorder: a review
    Deirdre Brennan
    School of Medicine and Medical Science, Health Sciences Building, University College Dublin, Belfield, Donnybrook, Dublin 4 Ireland
    Curr Pharm Des 20:5377-87. 2014
    ..Lastly, we review how current knowledge of early eye development can be used to gain new insights into the molecular mechanisms of ethanol teratogenicity with particular reference to the sonic hedgehog pathway...
  3. ncbi request reprint Teratogenic and developmental effects of lithium
    James J Giles
    Department of Human Anatomy and Physiology and Conway Institute of Biomolecular and Biomedical Research, National University of Ireland, Dublin, Ireland
    Curr Pharm Des 12:1531-41. 2006
    ..More recent findings have shown that the effects of lithium on invertebrates may be mediated through inhibition of GSK-3beta in the Wnt-GSK-3 pathway...
  4. ncbi request reprint Sonic hedgehog expression is disrupted following in ovo ethanol exposure during early chick eye development
    Deirdre Brennan
    School of Medicine and Medical Science, University College Dublin, Belfield, Ireland
    Reprod Toxicol 41:49-56. 2013
    ..Thus, in conclusion, our findings are discussed in relation to the varied and often conflicting reports of ethanol-induced Shh perturbation found in the literature. ..
  5. ncbi request reprint Histological characterisation of the ethanol-induced microphthalmia phenotype in a chick embryo model system
    Kevin Kennelly
    School of Medicine and Medical Science, Health Sciences Building, University College Dublin, Belfield, Dublin 4, Ireland
    Reprod Toxicol 32:227-34. 2011
    ..The possible involvement of Shh, Fgf8, Bmp4 and Pax6 is discussed in relation to these outcomes...