R J Fitzgerald

Summary

Affiliation: University of Limerick
Country: Ireland

Publications

  1. ncbi request reprint Hypotensive peptides from milk proteins
    Richard J FitzGerald
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    J Nutr 134:980S-8S. 2004
  2. ncbi request reprint Inhibition of dipeptidyl peptidase IV (DPP-IV) by tryptophan containing dipeptides
    Alice B Nongonierma
    Department of Life Sciences and Food for Health Ireland FHI, University of Limerick, Castletroy, Limerick, Ireland
    Food Funct 4:1843-9. 2013
  3. ncbi request reprint Cardioprotective peptides from marine sources
    Padraigin A Harnedy
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    Curr Protein Pept Sci 14:162-72. 2013
  4. doi request reprint Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions
    Alice B Nongonierma
    Department of Life Sciences and Food for Health Ireland, University of Limerick, Castletroy, Limerick, Ireland
    Food Funct 4:728-37. 2013
  5. ncbi request reprint Enzymatic debittering of food protein hydrolysates
    R J Fitzgerald
    Life Sciences Department, University of Limerick, Ireland
    Biotechnol Adv 24:234-7. 2006
  6. ncbi request reprint In vitro generation and stability of the lactokinin beta-lactoglobulin fragment (142-148)
    D J Walsh
    Department of Life Sciences, University of Limerick, Ireland
    J Dairy Sci 87:3845-57. 2004
  7. ncbi request reprint Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production
    B A Murray
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    Curr Pharm Des 13:773-91. 2007
  8. doi request reprint Antioxidative peptides: enzymatic production, in vitro and in vivo antioxidant activity and potential applications of milk-derived antioxidative peptides
    O Power
    Food for Health Ireland, Department of Life Sciences, University of Limerick, Schrödinger Building, Limerick, Ireland
    Amino Acids 44:797-820. 2013
  9. ncbi request reprint Food protein hydrolysates as a source of dipeptidyl peptidase IV inhibitory peptides for the management of type 2 diabetes
    Orla Power
    Department of Life Sciences, University of Limerick, Castletroy, Limerick, Ireland
    Proc Nutr Soc 73:34-46. 2014
  10. doi request reprint Whey protein isolate polydispersity affects enzymatic hydrolysis outcomes
    I B O'Loughlin
    Teagasc Food Research Centre, Moorepark, Fermoy, Co Cork, Ireland
    Food Chem 141:2334-42. 2013

Collaborators

  • O Power
  • H Bernard
  • B A Murray
  • Alice B Nongonierma
  • David Spellman
  • John Flanagan
  • Padraigin A Harnedy
  • I B O'Loughlin
  • A B Nongonierma
  • D J Walsh
  • Birgit Teucher
  • Gerard O'Cuinn
  • A A Robinson
  • T A Holton
  • Harriet Schellekens
  • Timothy G Dinan
  • A Brodkorb
  • John F Cryan
  • P M Kelly
  • Gosia Majsak-Newman
  • Jack R Dainty
  • David McDonagh
  • Susan J Fairweather-Tait
  • Patricia Kenny
  • H Meisel
  • G A Wright
  • A K Pentzien
  • A D Struthers
  • J MacDonald
  • J M Wal

Detail Information

Publications17

  1. ncbi request reprint Hypotensive peptides from milk proteins
    Richard J FitzGerald
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    J Nutr 134:980S-8S. 2004
    ..The advent of effective milk protein based functional food ingredients/nutraceuticals for the prevention/control of blood pressure therefore has the potential to significantly reduce global healthcare cost...
  2. ncbi request reprint Inhibition of dipeptidyl peptidase IV (DPP-IV) by tryptophan containing dipeptides
    Alice B Nongonierma
    Department of Life Sciences and Food for Health Ireland FHI, University of Limerick, Castletroy, Limerick, Ireland
    Food Funct 4:1843-9. 2013
    ..This in turn may dictate a more targeted approach for the release of potent peptides from milk proteins with the view of developing biofunctional hydrolysates for the management of type 2 diabetes...
  3. ncbi request reprint Cardioprotective peptides from marine sources
    Padraigin A Harnedy
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    Curr Protein Pept Sci 14:162-72. 2013
    ..Furthermore, products containing protein hydrolysates/peptides from marine origin with antihypertensive effects are discussed. ..
  4. doi request reprint Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions
    Alice B Nongonierma
    Department of Life Sciences and Food for Health Ireland, University of Limerick, Castletroy, Limerick, Ireland
    Food Funct 4:728-37. 2013
    ..These results reinforce the potential of milk-derived bioactive peptides to be developed into functional foods targeted at 5-HT(2C) receptor modulation...
  5. ncbi request reprint Enzymatic debittering of food protein hydrolysates
    R J Fitzgerald
    Life Sciences Department, University of Limerick, Ireland
    Biotechnol Adv 24:234-7. 2006
    ..Practical solutions to hydrolysate debittering are likely to involve judicious choice of enzymatic processing conditions in conjunction with the use of peptidase activities having targeted hydrolytic specificity...
  6. ncbi request reprint In vitro generation and stability of the lactokinin beta-lactoglobulin fragment (142-148)
    D J Walsh
    Department of Life Sciences, University of Limerick, Ireland
    J Dairy Sci 87:3845-57. 2004
    ..The in vitro methodology described herein has general application in evaluating the hypotensive potential of food protein-derived ACE inhibitory peptides...
  7. ncbi request reprint Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production
    B A Murray
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    Curr Pharm Des 13:773-91. 2007
    ..Detailed human studies are required in order to demonstrate the efficacy of these bioactive peptides prior to their widespread utilisation as physiologically beneficial functional foods/food ingredients...
  8. doi request reprint Antioxidative peptides: enzymatic production, in vitro and in vivo antioxidant activity and potential applications of milk-derived antioxidative peptides
    O Power
    Food for Health Ireland, Department of Life Sciences, University of Limerick, Schrödinger Building, Limerick, Ireland
    Amino Acids 44:797-820. 2013
    ..The potential applications and health benefits of antioxidant peptides are discussed with a particular focus on the aging population. The regulatory requirements for peptide-based antioxidant functional foods are also considered...
  9. ncbi request reprint Food protein hydrolysates as a source of dipeptidyl peptidase IV inhibitory peptides for the management of type 2 diabetes
    Orla Power
    Department of Life Sciences, University of Limerick, Castletroy, Limerick, Ireland
    Proc Nutr Soc 73:34-46. 2014
    ..Therefore, milk protein derived peptide inhibitors may be a unique multifunctional peptide approach for the management of T2DM. ..
  10. doi request reprint Whey protein isolate polydispersity affects enzymatic hydrolysis outcomes
    I B O'Loughlin
    Teagasc Food Research Centre, Moorepark, Fermoy, Co Cork, Ireland
    Food Chem 141:2334-42. 2013
    ..The outcomes of the study emphasise how a combined approach of substrate heat pre-treatment and enzymology may be used to influence proteolysis with attendant opportunities for targeting unique peptide production and amino acid release...
  11. doi request reprint Biofunctional properties of caseinophosphopeptides in the oral cavity
    A B Nongonierma
    Department of Life Sciences and Food for Health Ireland FHI, University of Limerick, Limerick, Ireland
    Caries Res 46:234-67. 2012
    ..Nevertheless, relatively little is known concerning their use as adjuvants for oral health and more particularly regarding their long-term effects on oral health...
  12. ncbi request reprint Modification of the furanacryloyl-L-phenylalanylglycylglycine assay for determination of angiotensin-I-converting enzyme inhibitory activity
    B A Murray
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    J Biochem Biophys Methods 59:127-37. 2004
    ..The results demonstrate the requirement for carefully controlling ACE activity levels in the assay in order to obtained comparable and reproducible values for the inhibitory potency of ACE inhibitors...
  13. ncbi request reprint Physicochemical and nitrogen solubility properties of Bacillus proteinase hydrolysates of sodium caseinate incubated with transglutaminase pre- and post-hydrolysis
    John Flanagan
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    J Agric Food Chem 50:5429-36. 2002
    ..Combination of enzymatic treatments resulted in significantly (P < 0.005) improved solubility around pH 4.6, compared to incubation with TGase or hydrolysis of NaCN alone...
  14. ncbi request reprint Physicochemical and sensory characteristics of whey protein hydrolysates generated at different total solids levels
    David Spellman
    Department of Life Sciences, University of Limerick, Republic of Ireland
    J Dairy Res 72:138-43. 2005
    ....
  15. ncbi request reprint Aggregation properties of whey protein hydrolysates generated with Bacillus licheniformis proteinase activities
    David Spellman
    Department of Life Sciences, University of Limerick, Ireland
    J Agric Food Chem 53:1258-65. 2005
    ..These results emphasize the contribution of enzyme specificity to the physicochemical and functional characteristics of proteinase hydrolysates of WPC...
  16. ncbi request reprint Characterisation and quantification of the reaction(s) catalysed by transglutaminase using the o-phthaldialdehyde reagent
    John Flanagan
    Department of Life Sciences, University of Limerick, Limerick, Ireland
    Nahrung 47:207-12. 2003
    ..However, the observed decrease in epsilon-amino group concentration was higher than expected. This may be due to concealment of noncross-linked amino groups in polymerised NaCN, making them unavailable for reaction with the OPA reagent...
  17. ncbi request reprint Calcium absorption is not increased by caseinophosphopeptides
    Birgit Teucher
    Institute of Food Research, Norwich, United Kingdom
    Am J Clin Nutr 84:162-6. 2006
    ..This possibility is based on the assumption that they resist proteolysis in the upper gastrointestinal tract and maintain calcium in a soluble form at alkaline pH in the distal ileum...