Research Topics
| Eoin R FeeneySummaryAffiliation: University College Dublin Country: Ireland Publications
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Detail Information
Publications
Impact of mitochondrial toxicity of HIV-1 antiretroviral drugs on lipodystrophy and metabolic dysregulationEoin R Feeney
School of Medicine and Medical Sciences, University College Dublin, C339 Health Sciences Building, Dublin 4, Ireland
Curr Pharm Des 16:3339-51. 2010..Using the example of HIV-associated lipodystrophy (HIVLD) as a model of clinical MtT we discuss management strategies and the potential for these toxicities to impact on future ARV development...
Hyperlactataemia in HIV-infected subjects initiating antiretroviral therapy in a large randomized study (a substudy of the INITIO trial)E R Feeney
HIV Molecular Research Group, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland
HIV Med 12:602-9. 2011....
Insulin resistance in treated HIV infectionE R Feeney
HIV Molecular Research Group, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
Best Pract Res Clin Endocrinol Metab 25:443-58. 2011..Optimal screening and treatment strategies for IR in treated HIV infection have not been established. In this article we review current opinion on insulin resistance in HIV and identify potential areas for future research...
Increased platelet reactivity in HIV-1-infected patients receiving abacavir-containing antiretroviral therapyClaudette S Satchell
HIV Molecular Research Group, School of Medicine and Medical Sciences, University College Dublin, Ireland
J Infect Dis 204:1202-10. 2011..Given the role of platelet aggregation in thrombus formation in MI and the reversible nature of the abacavir association, we hypothesized that patients treated with abacavir would have increased platelet reactivity...
The expression of cholesterol metabolism genes in monocytes from HIV-infected subjects suggests intracellular cholesterol accumulationEoin R Feeney
HIV Molecular Research Group, School of Medicine and Medical Science, University College Dublin, Ireland
J Infect Dis 207:628-37. 2013..In vitro, HIV impairs monocyte-macrophage cholesterol efflux, a major determinant of circulating HDL-c, by increasing ABCA1 degradation, with compensatory upregulation of ABCA1 messenger RNA (mRNA)...
Zidovudine/lamivudine but not nevirapine in combination with lopinavir/ritonavir decreases subcutaneous adipose tissue mitochondrial DNAEoin R Feeney
HIV Molecular Research Group, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
AIDS 26:2165-74. 2012..No randomized study has prospectively followed subcutaneous adipose tissue mitochondrial DNA (mtDNA) changes when starting thymidine nucleoside reverse transcriptase inhibitors (tNRTIs)...
High-density lipoprotein levels and 10-year cardiovascular risk in HIV-1-infected patientsAoife G Cotter
HIV Molecular Research Group, School of Medicine and Medical Science, University College Dublin, Ireland
AIDS 25:867-9. 2011..In this cohort, HDL-c contributed more to cardiovascular risk than smoking, total cholesterol, systolic blood pressure (SBP) and sex...
HIV and HAART-Associated DyslipidemiaEoin R Feeney
HIV Molecular Research Group, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
Open Cardiovasc Med J 5:49-63. 2011....
