Karen England

Summary

Affiliation: University College Cork
Country: Ireland

Publications

  1. ncbi PKC epsilon is associated with myosin IIA and actin in fibroblasts
    Karen England
    Department of Biology, University of York, York YO10 5DD, UK
    Cell Signal 14:529-36. 2002
  2. ncbi Identification of carbonylated proteins by MALDI-TOF mass spectroscopy reveals susceptibility of ER
    K England
    Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland
    Biochem Biophys Res Commun 320:123-30. 2004
  3. ncbi Methods to study dephosphorylation of protein kinase C in vivo
    Karen England
    Biochemistry Department, University College Cork, Ireland
    Methods Mol Biol 233:217-32. 2003
  4. ncbi ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis
    Karen England
    Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland
    Free Radic Res 40:1124-37. 2006
  5. ncbi 'Shotgun immunological' approach for analysis of a complex subcellular system
    John J Mackrill
    Department of Physiology, NUI University College Cork, Cork, Ireland
    Int J Mol Med 23:399-405. 2009
  6. ncbi Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK
    Fionnuala B Hickey
    Department of Biochemistry, Biosciences Institute, University College Cork, Ireland
    J Leukoc Biol 78:289-300. 2005
  7. ncbi Phosphorylation at Ser729 specifies a Golgi localisation for protein kinase C epsilon (PKCepsilon) in 3T3 fibroblasts
    Tian Rui Xu
    SHWFGF Proteomics Section, Joseph Black Building, University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK
    Cell Signal 19:1986-95. 2007

Collaborators

  • John J Mackrill
  • Tian Rui Xu
  • Fionnuala B Hickey
  • Guiyuan He
  • Martin Rumsby
  • Kath Dobson
  • Tian-Rui Xu
  • Thomas G Cotter

Detail Information

Publications7

  1. ncbi PKC epsilon is associated with myosin IIA and actin in fibroblasts
    Karen England
    Department of Biology, University of York, York YO10 5DD, UK
    Cell Signal 14:529-36. 2002
    ..Inhibitors of PKC and myosin ATPase activity, as well as microfilament-disrupting drugs, all inhibited spreading of fibroblasts after passage, suggesting a role for a PKC epsilon-actin-myosin complex in cell spreading...
  2. ncbi Identification of carbonylated proteins by MALDI-TOF mass spectroscopy reveals susceptibility of ER
    K England
    Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland
    Biochem Biophys Res Commun 320:123-30. 2004
    ..The results show that some ER proteins are readily carbonylated in response to peroxide treatment of HL-60 cells. This is likely to have implications for the induction of cell death in such cells...
  3. ncbi Methods to study dephosphorylation of protein kinase C in vivo
    Karen England
    Biochemistry Department, University College Cork, Ireland
    Methods Mol Biol 233:217-32. 2003
  4. ncbi ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis
    Karen England
    Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland
    Free Radic Res 40:1124-37. 2006
    ..This study demonstrates the importance of ROS mediated protein modifications in the induction of the early stages of apoptosis in response to chemotherapeutic drug treatment...
  5. ncbi 'Shotgun immunological' approach for analysis of a complex subcellular system
    John J Mackrill
    Department of Physiology, NUI University College Cork, Cork, Ireland
    Int J Mol Med 23:399-405. 2009
    ..Such 'shotgun immunological' strategies will prove effective in characterising novel constituents of, as well as for investigating protein-protein interactions within, macromolecular structures isolated from biological systems...
  6. ncbi Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK
    Fionnuala B Hickey
    Department of Biochemistry, Biosciences Institute, University College Cork, Ireland
    J Leukoc Biol 78:289-300. 2005
    ..This may not only prove important in understanding the mechanisms of progression of CML but also highlights a pathway that may prove significant in many other cases of oncogenesis, where OPN expression is implicated...
  7. ncbi Phosphorylation at Ser729 specifies a Golgi localisation for protein kinase C epsilon (PKCepsilon) in 3T3 fibroblasts
    Tian Rui Xu
    SHWFGF Proteomics Section, Joseph Black Building, University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK
    Cell Signal 19:1986-95. 2007
    ..The results indicate that Ser729 phosphorylation plays a role in determining PKCepsilon localisation in fibroblasts...