Timothy Dinan

Summary

Affiliation: University College Cork
Country: Ireland

Publications

  1. ncbi request reprint Therapeutic options: Addressing the current dilemma
    Timothy Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University of Cork, Cork, Ireland
    Eur Neuropsychopharmacol 16:S119-27. 2006
  2. doi request reprint Prolactin and dopamine: what is the connection? A review article
    Peter Fitzgerald
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    J Psychopharmacol 22:12-9. 2008
  3. pmc Brain-gut-microbe communication in health and disease
    Sue Grenham
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, University College Cork Cork, Ireland
    Front Physiol 2:94. 2011
  4. ncbi request reprint Psychobiotics: a novel class of psychotropic
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork and Teagasc Moorepark, Cork, Ireland Electronic address
    Biol Psychiatry 74:720-6. 2013
  5. doi request reprint Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Psychoneuroendocrinology 37:1369-78. 2012
  6. pmc Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort
    Gerard Clarke
    Department of Psychiatry, University College Cork, Cork, Ireland
    BMC Gastroenterol 9:6. 2009
  7. doi request reprint MicroRNAs as a target for novel antipsychotics: a systematic review of an emerging field
    Timothy G Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Int J Neuropsychopharmacol 13:395-404. 2010
  8. doi request reprint Investigating the inflammatory phenotype of major depression: focus on cytokines and polyunsaturated fatty acids
    Timothy Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Wilton, Cork, Ireland
    J Psychiatr Res 43:471-6. 2009
  9. ncbi request reprint Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker?
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Gastroenterology 130:304-11. 2006
  10. ncbi request reprint Stress: the shared common component in major mental illnesses
    T G Dinan
    Alimentary Pharmabiotic Centre, Department of Psychiatry, University College Cork, Wilton, Cork, Ireland
    Eur Psychiatry 20:S326-8. 2005

Collaborators

Detail Information

Publications60

  1. ncbi request reprint Therapeutic options: Addressing the current dilemma
    Timothy Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University of Cork, Cork, Ireland
    Eur Neuropsychopharmacol 16:S119-27. 2006
    ..To achieve this goal, physicians need a more effective, faster acting, safer, and better tolerated drug than the many existing GAD treatments...
  2. doi request reprint Prolactin and dopamine: what is the connection? A review article
    Peter Fitzgerald
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    J Psychopharmacol 22:12-9. 2008
    ..g. risperidone, 9-hydroxy-risperidone and amisulpride). Antipsychotics that easily cross the blood-brain barrier and exhibit fast dissociation from the dopamine receptor once bound do not result in sustained hyperprolactinaemia...
  3. pmc Brain-gut-microbe communication in health and disease
    Sue Grenham
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, University College Cork Cork, Ireland
    Front Physiol 2:94. 2011
    ..Despite the considerable challenges that lie ahead, this is an exciting area of research and one that is destined to remain the center of focus for some time to come...
  4. ncbi request reprint Psychobiotics: a novel class of psychotropic
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork and Teagasc Moorepark, Cork, Ireland Electronic address
    Biol Psychiatry 74:720-6. 2013
    ..Such benefits may be related to the anti-inflammatory actions of certain psychobiotics and a capacity to reduce hypothalamic-pituitary-adrenal axis activity. Results from large scale placebo-controlled studies are awaited. ..
  5. doi request reprint Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Psychoneuroendocrinology 37:1369-78. 2012
    ..It is however clear that the gut microbiota must be taken into account when considering the factors regulating the HPA...
  6. pmc Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort
    Gerard Clarke
    Department of Psychiatry, University College Cork, Cork, Ireland
    BMC Gastroenterol 9:6. 2009
    ..In this study, we investigated tryptophan degradation in a male IBS cohort (n = 10) and control subjects (n = 26)...
  7. doi request reprint MicroRNAs as a target for novel antipsychotics: a systematic review of an emerging field
    Timothy G Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Int J Neuropsychopharmacol 13:395-404. 2010
    ..It will require a considerable advance in smart technologies to deliver either mimics or antagomirs to the appropriate site of action, but the development of selective small conventional molecules may negate this requirement...
  8. doi request reprint Investigating the inflammatory phenotype of major depression: focus on cytokines and polyunsaturated fatty acids
    Timothy Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Wilton, Cork, Ireland
    J Psychiatr Res 43:471-6. 2009
    ..The findings of this study provide further support for the view that major depression is associated with a pro-inflammatory phenotype which at least partially persists when patients become normothymic...
  9. ncbi request reprint Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker?
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Gastroenterology 130:304-11. 2006
    ..The primary aim of this study was to examine the hypothalamic-pituitary-adrenal axis in patients with IBS and to relate such response to plasma cytokine profiles...
  10. ncbi request reprint Stress: the shared common component in major mental illnesses
    T G Dinan
    Alimentary Pharmabiotic Centre, Department of Psychiatry, University College Cork, Wilton, Cork, Ireland
    Eur Psychiatry 20:S326-8. 2005
  11. ncbi request reprint Stress and the genesis of diabetes mellitus in schizophrenia
    Timothy G Dinan
    Department of Psychiatry, University College Cork, Ireland
    Br J Psychiatry Suppl 47:S72-5. 2004
    ..Antipsychotic drugs have been implicated in the development of diabetes, but as non-medicated patients with schizophrenia have high rates of diabetes it is likely that factors other than medication are involved...
  12. doi request reprint IBS: An epigenetic perspective
    Timothy G Dinan
    Alimentary Pharmabiotic Center, University College Cork, Cork, Ireland
    Nat Rev Gastroenterol Hepatol 7:465-71. 2010
    ..We conclude that applying epigenetic methodology to this common and disabling disorder may help unravel its complex pathophysiology and lead to more effective treatments...
  13. pmc Anatomy of melancholia: focus on hypothalamic-pituitary-adrenal axis overactivity and the role of vasopressin
    Timothy G Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, Cork University Hospital, Ireland
    J Anat 207:259-64. 2005
    ..By contrast, vasopressin V3 receptors on the anterior pituitary show enhanced response to AVP stimulation and this enhancement plays a key role in maintaining HPA overactivity...
  14. doi request reprint Inflammatory markers in depression
    Timothy G Dinan
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Curr Opin Psychiatry 22:32-6. 2009
    ..To provide a critical update of the literature linking depression and inflammation, together with possible underlying mechanisms and longer term risk of cardiovascular disease...
  15. ncbi request reprint Schizophrenia and diabetes 2003: an expert consensus meeting. Introduction
    Timothy G Dinan
    Department of Psychiatry, University College, Cork, Ireland
    Br J Psychiatry Suppl 47:S53-4. 2004
  16. doi request reprint Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model
    S O'Mahony
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Neurogastroenterol Motil 20:680-8. 2008
    ..In conclusion altered central serotonin responses are found in both IBS and in an animal model...
  17. doi request reprint The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat
    Lieve Desbonnet
    Department of Psychiatry and Alimentary Pharmacobiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland
    J Psychiatr Res 43:164-74. 2008
    ..However, these findings are preliminary and further investigation into the precise mechanisms involved, is warranted...
  18. ncbi request reprint Vasopressin as a target for antidepressant development: an assessment of the available evidence
    Lucinda V Scott
    Department of Psychiatry, Cork University Hospital, Cork, Ireland
    J Affect Disord 72:113-24. 2002
    ..We suggest that future antidepressants may target the vasopressinergic system...
  19. doi request reprint Sexually dimorphic effects of maternal separation stress on corticotrophin-releasing factor and vasopressin systems in the adult rat brain
    Lieve Desbonnet
    Department of Psychiatry and Alimentary Pharmacobiotic Centre, University College Cork, Cork, Ireland
    Int J Dev Neurosci 26:259-68. 2008
    ..Furthermore, the sexually dimorphic effects of maternal separation on these neuropeptides indicate that gender is an important factor influencing the trajectory of early life stress effects on CRF and AVP systems in the brain...
  20. doi request reprint Menstrual cycle influences Toll-like receptor responses
    Una Dennison
    Department of Psychiatry, University College Cork, Cork, Ireland
    Neuroimmunomodulation 19:171-9. 2012
    ..Human studies have shown changes in endometrial TLR expression during the menstrual cycle and during pregnancy. Our objective was to measure peripheral TLR activity over the course of the menstrual cycle...
  21. doi request reprint Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?
    Gerard Clarke
    Department of Psychiatry, Biosciences Institute, University College Cork, Cork, Ireland
    Hum Psychopharmacol 24:217-23. 2009
    ..In this study we examined the hypothesis that the antidepressant-like effects of verapamil are mediated through its blockade of the Pgp transporter in the blood brain barrier (BBB)...
  22. doi request reprint Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood
    Gerard Clarke
    Department of Psychiatry, University College Cork, Cork, Ireland Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Behav Brain Res 205:319-21. 2009
    ..Our results identify a proinflammatory PUFA profile as a persistent consequence of early-life stress and suggest new avenues of investigation in stress-related disorders...
  23. doi request reprint Irritable bowel syndrome: towards biomarker identification
    Gerard Clarke
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Trends Mol Med 15:478-89. 2009
    ..The successful identification of biomarkers is critical to progressing our understanding of IBS and addressing the unmet therapeutic needs of this debilitating condition...
  24. pmc Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome
    Gerard Clarke
    Department of Psychiatry, University College Cork, Cork, Ireland
    J Lipid Res 51:1186-92. 2010
    ..Together, our data identifies a novel proinflammatory mechanism in irritable bowel syndrome and also suggests that elevated arachidonic acid levels in plasma may serve as putative biological markers in this condition...
  25. doi request reprint Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: differential effects of acute psychological and physical stressors
    Dervla O'Malley
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Peptides 31:662-70. 2010
    ..This study demonstrates that acute stressors alter colonic CRF receptor expression in a manner that is determined by the underlying stress sensitivity of the subject...
  26. doi request reprint Maternal separation as a model of brain-gut axis dysfunction
    Siobhain M O'Mahony
    Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland
    Psychopharmacology (Berl) 214:71-88. 2011
    ..Accumulating evidence suggest that stress, especially in early life, is a predisposing factor to IBS...
  27. doi request reprint Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors
    Timothy G Dinan
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Am J Gastroenterol 103:2570-6. 2008
    ..We tested the hypothesis that the pro-inflammatory cytokine profile in IBS is driven by the cholinergic system and determined if the responses are mediated by muscarinic receptors...
  28. doi request reprint Mucosal cytokine imbalance in irritable bowel syndrome
    John Macsharry
    Alimentary Health Ltd, Cork, Ireland
    Scand J Gastroenterol 43:1467-76. 2008
    ..To systematically examine mucosal biopsies for differences in cytokine gene expression and protein secretion...
  29. doi request reprint Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses
    Siobhain M O'Mahony
    Alimentary Pharmabiotic Centre, Cork, Ireland
    Biol Psychiatry 65:263-7. 2009
    ..This makes the identification of the neurobiological substrates that are affected by adverse experiences in early life invaluable...
  30. ncbi request reprint Cytokine profiles in bipolar affective disorder: focus on acutely ill patients
    Sinead M O'Brien
    Alimentary Pharmabiotic Centre and Department of Psychiatry, University College Cork, Wilton, Cork, Ireland
    J Affect Disord 90:263-7. 2006
    ..However activation of the immune system has also been demonstrated in bipolar mania. Our study examines pro-inflammatory and anti-inflammatory cytokines in both phases of bipolar affective disorder (BPAD)...
  31. doi request reprint Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues
    Marcela Julio-Pieper
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Pharmacol Rev 63:35-58. 2011
    ..This review summarizes the new potential roles of mGlu receptors and raises the possibility of novel pharmacological targets for various disorders...
  32. doi request reprint Increased tumor necrosis factor-alpha concentrations with interleukin-4 concentrations in exacerbations of schizophrenia
    Sinead M O'Brien
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Psychiatry Res 160:256-62. 2008
    ..Acute exacerbations of schizophrenia are associated with increased TNF-alpha concentrations (Th1) with concomitantly reduced concentrations of IL-4 (Th2) and a resulting increased TNF-alpha/IL-4 ratio...
  33. doi request reprint Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour
    Dervla O'Malley
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland
    Stress 13:114-22. 2010
    ..This study provides evidence of altered colonic function and morphology in two animal models with a heightened response to stress...
  34. doi request reprint Comparison of hippocampal metabotropic glutamate receptor 7 (mGlu7) mRNA levels in two animal models of depression
    Cliona M O'Mahony
    Neuropharmacology Research Group, Dept of Pharmacology and Therapeutics, University College Cork, Ireland
    Neurosci Lett 482:137-41. 2010
    ....
  35. ncbi request reprint Cytokines: abnormalities in major depression and implications for pharmacological treatment
    Sinead M O'Brien
    Department of Psychiatry, University College Cork, Cork University Hospital, Wilton Road, Cork, Ireland
    Hum Psychopharmacol 19:397-403. 2004
    ..We suggest that future antidepressants may target the immune system by either blocking the actions of pro-inflammatory cytokines or increasing the production of anti-inflammatory cytokines...
  36. ncbi request reprint An isocratic high performance liquid chromatography method for the determination of GABA and glutamate in discrete regions of the rodent brain
    Gerard Clarke
    Alimentary Pharmabiotic Centre and Department of Psychiatry, University College Cork, Cork, Ireland
    J Neurosci Methods 160:223-30. 2007
    ..Successful application of the method to a maternal deprivation study has identified the hippocampus and the brainstem as possible sites of long-term alteration in this paradigm...
  37. doi request reprint Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms
    Romain Daniel Gosselin
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Gastroenterology 138:2418-25. 2010
    ..Because alterations in spinal non-neuronal (astrocytic) glutamate reuptake are suspected to participate in chronic pain, we asked whether such processes occur in visceral hypersensitivity...
  38. doi request reprint "Killing the Blues": a role for cellular suicide (apoptosis) in depression and the antidepressant response?
    Declan P McKernan
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Prog Neurobiol 88:246-63. 2009
    ....
  39. ncbi request reprint Pituitary-adrenal response to naloxone in non-ulcer dyspepsia: preliminary evidence for a reduction in central opioid tone
    Lucinda V Scott
    Department of Psychiatry, Cork University, Wilton, Cork, Ireland
    Digestion 65:67-72. 2002
    ..The opioid system is known to govern nociceptive processing and to play a role in gut motor activity...
  40. pmc Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    Marcus J Claesson
    Department of Microbiology, University College, Cork, Ireland
    Proc Natl Acad Sci U S A 108:4586-91. 2011
    ..We conclude that the fecal microbiota of the elderly shows temporal stability over limited time in the majority of subjects but is characterized by unusual phylum proportions and extreme variability...
  41. ncbi request reprint Executive function in schizophrenia: what impact do antipsychotics have?
    Cara O'Gráda
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Hum Psychopharmacol 22:397-406. 2007
    ..Issues significant to future psychopharmacology in the area are discussed, with particular emphasis on the need for a greater consensus in methodology and definition executive function research in schizophrenia...
  42. doi request reprint Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour
    Cliona M O'Mahony
    Neuropharmacology Research Group, University College Cork, Cork, Ireland
    Behav Brain Res 213:148-54. 2010
    ..The lower levels of stress-induced activity in high anxiety BALB/c mice, possibly indicate a circuit dysregulation at the cortico-limbic level in response to stress...
  43. ncbi request reprint Cutaneous glucocorticoid receptor sensitivity and pro-inflammatory cytokine levels in antidepressant-resistant depression
    Peter Fitzgerald
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Psychol Med 36:37-43. 2006
    ..The present study sought to assess the sensitivity of peripheral GRs in antidepressant-resistant major depressives and investigate the association between GR sensitivity and circulating plasma cytokines...
  44. ncbi request reprint Antidepressant therapy and C-reactive protein levels
    Sinead M O'Brien
    Department of Psychiatry and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Br J Psychiatry 188:449-52. 2006
    ..Major depression is associated with activation of the inflammatory response...
  45. pmc Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome
    Declan P McKernan
    Laboratory of Neurogastroenterology, Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    PLoS ONE 4:e8226. 2009
    ..It was our hypothesis that innate immune receptor expression may be changed in the gastrointestinal tract of animals with stress-induced IBS-like symptoms...
  46. ncbi request reprint Functional dyspepsia: are psychosocial factors of relevance?
    Sandra Barry
    Department of Psychiatry, Alimentary Pharmacobiotic Centre, University College Cork, Cork, Ireland
    World J Gastroenterol 12:2701-7. 2006
    ..The rationale for use of psychotropic medications in FD is apparent but the evidence base to support the use of antidepressant pharmacotherapy is to date limited...
  47. ncbi request reprint Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy
    Paul Scully
    Alimentary Pharmabiotic Centre and Department of Psychiatry, Cork University Hospital, Wilton, Cork, Ireland
    J Psychiatr Res 41:326-31. 2007
    ..Studies suggest that overall patients with depression show increased production of proinflammatory cytokines. We examined pro- and anti-inflammatory cytokine levels in patients who were SSRI resistant...
  48. doi request reprint Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity
    Paul Scully
    Alimentary Pharmabiotic Centre, University College Cork, Ireland
    Am J Gastroenterol 105:2235-43. 2010
    ..This study was designed to examine the cytokine profile among a group of IBS patients with the extra-intestinal co-morbidities fibromyalgia, premenstrual dysmorphic disorder, and chronic fatigue syndrome...
  49. ncbi request reprint MicroRNAs: a novel therapeutic target for schizophrenia
    Javier A Bravo
    Department of Psychiatry, Cork University Hospital, Wilton, Cork, Ireland
    Curr Pharm Des 17:176-88. 2011
    ..However, technology is still developing in order to produce effective strategies to modulate specific and localized changes in miRNA, particularly in relation to the central nervous system and schizophrenia...
  50. ncbi request reprint Platelet surface glycoprotein expression in post-stroke depression: a preliminary study
    Eugene M Cassidy
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland
    Psychiatry Res 118:175-81. 2003
    ..Platelet dysfunction may be involved in the pathophysiological process underlying the association between depression and cerebrovascular disease...
  51. doi request reprint Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours
    Beate C Finger
    School of Pharmacy, Cavanagh Pharmacy Building, University College Cork, Cork, Ireland
    Psychopharmacology (Berl) 210:559-68. 2010
    ..Leptin, encoded by the ob gene, plays an important part in the energy homeostasis and is critical for the development of obesity...
  52. doi request reprint Impact of administered bifidobacterium on murine host fatty acid composition
    Rebecca Wall
    Alimentary Pharmabiotic Centre, Co Cork, Ireland
    Lipids 45:429-36. 2010
    ..This interaction between administered microbes and fatty acids could result in a highly effective nutritional approach to the therapy of a variety of inflammatory and neurodegenerative conditions...
  53. ncbi request reprint Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib
    Marie Therese Walsh
    Department of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephen s Green, 2, Dublin, Ireland
    Life Sci 70:3155-65. 2002
    ..The results of this study demonstrate that the number of GPIb receptors on platelets are increased in depression and suggest a novel risk factor for thrombosis in patients with depression...
  54. doi request reprint Is "clinical" insight the same as "cognitive" insight in schizophrenia?
    Gary Donohoe
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    J Int Neuropsychol Soc 15:471-5. 2009
    ..We conclude that while good cognitive insight may not be necessary for good clinical insight, good cognitive awareness is at least partly reliant on the processes involved in clinical insight...
  55. ncbi request reprint Impact of gender and menstrual cycle phase on plasma cytokine concentrations
    Sinead M O'Brien
    Alimentary Pharmabiotic Centre, Department of Psychiatry, Cork University Hospital, Cork, Ireland
    Neuroimmunomodulation 14:84-90. 2007
    ..We examined pro- and anti-inflammatory cytokine levels during the normal menstrual cycle of healthy females compared to similar time points in healthy males...
  56. doi request reprint Does the ability to sustain attention underlie symptom severity in schizophrenia?
    Cara O'Gráda
    Department of Psychiatry, University College Cork, Ireland
    Schizophr Res 107:319-23. 2009
    ..These data suggest that this component of attention at least partly explains variance in negative symptoms...
  57. ncbi request reprint Atypical antipsychotics and diabetic propensity: more questions than answers?
    Timothy G Dinan
    Hum Psychopharmacol 18:591-3. 2003
  58. ncbi request reprint A preliminary study of buspirone stimulated prolactin release in generalised social phobia: evidence for enhanced serotonergic responsivity?
    Rita M Condren
    Neuroscience Department, St Vincent s Hospital, Richmond Rd, Fairview, Dublin 3, Ireland
    Eur Neuropsychopharmacol 12:349-54. 2002
    ..Patients with generalised social phobia had enhanced central serotonergic responses, an abnormality shared with some other anxiety disorders and which may be of aetiological significance...