Kevin Cashman

Summary

Affiliation: University College Cork
Country: Ireland

Publications

  1. ncbi request reprint Vitamin D intakes in 18-64-y-old Irish adults
    T R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 58:1509-17. 2004
  2. doi request reprint EURRECA-Estimating vitamin D requirements for deriving dietary reference values
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Crit Rev Food Sci Nutr 53:1097-109. 2013
  3. pmc Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition and health surveys
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Am J Clin Nutr 97:1235-42. 2013
  4. doi request reprint Vitamin D status of Irish adults: findings from the National Adult Nutrition Survey
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Cork, Republic of Ireland
    Br J Nutr 109:1248-56. 2013
  5. doi request reprint Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
    Br J Nutr 106:1617-27. 2011
  6. doi request reprint A systematic review and meta-regression analysis of the vitamin D intake-serum 25-hydroxyvitamin D relationship to inform European recommendations
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
    Br J Nutr 106:1638-48. 2011
  7. doi request reprint Relative effectiveness of oral 25-hydroxyvitamin D3 and vitamin D3 in raising wintertime serum 25-hydroxyvitamin D in older adults
    Kevin D Cashman
    School of Food and Nutritional Sciences, Department of Medicine, University College Cork, Cork, Ireland
    Am J Clin Nutr 95:1350-6. 2012
  8. doi request reprint Dietary reference intervals for vitamin D
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, and Department of Medicine, University College Cork, Cork, Ireland
    Scand J Clin Lab Invest Suppl 243:136-43. 2012
  9. ncbi request reprint Diet, nutrition, and bone health
    Kevin D Cashman
    Department of Food and Nutritional Sciences and Department of Medicine, University College Cork, Cork, Ireland
    J Nutr 137:2507S-2512S. 2007
  10. ncbi request reprint Low vitamin D status adversely affects bone health parameters in adolescents
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Western Road, Cork, Ireland
    Am J Clin Nutr 87:1039-44. 2008

Detail Information

Publications80

  1. ncbi request reprint Vitamin D intakes in 18-64-y-old Irish adults
    T R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 58:1509-17. 2004
    ..To estimate vitamin D intakes in a representative sample of Irish adults and to assess the contribution of foods to these intake estimates...
  2. doi request reprint EURRECA-Estimating vitamin D requirements for deriving dietary reference values
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Crit Rev Food Sci Nutr 53:1097-109. 2013
    ..Supplementary materials are available for this article. Go to the publisher's onilne edition of Critical Reviews in Food Science and Nutrion for the following free supplemental files: Additional text, tables, and figures.]...
  3. pmc Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition and health surveys
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Am J Clin Nutr 97:1235-42. 2013
    ....
  4. doi request reprint Vitamin D status of Irish adults: findings from the National Adult Nutrition Survey
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Cork, Republic of Ireland
    Br J Nutr 109:1248-56. 2013
    ..5 % of Irish adults), it will have only very limited impact at a population level. Food-based strategies, including fortified foods, need to be explored...
  5. doi request reprint Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
    Br J Nutr 106:1617-27. 2011
    ..It is intended to be of use to researchers, national policy makers, the public health community, industry groups and other relevant stakeholders including funding institutions...
  6. doi request reprint A systematic review and meta-regression analysis of the vitamin D intake-serum 25-hydroxyvitamin D relationship to inform European recommendations
    Kevin D Cashman
    School of Food and Nutritional Sciences, University College Cork, Republic of Ireland
    Br J Nutr 106:1638-48. 2011
    ..The model used to describe the vitamin D intake-status relationship needs to be considered carefully when setting new reference intake values in the Europe...
  7. doi request reprint Relative effectiveness of oral 25-hydroxyvitamin D3 and vitamin D3 in raising wintertime serum 25-hydroxyvitamin D in older adults
    Kevin D Cashman
    School of Food and Nutritional Sciences, Department of Medicine, University College Cork, Cork, Ireland
    Am J Clin Nutr 95:1350-6. 2012
    ..The relative potency of 25-hydroxyvitamin D3 to vitamin D3 needs to be better defined so that food-composition tables can better reflect the true vitamin D nutritive value of certain foods...
  8. doi request reprint Dietary reference intervals for vitamin D
    Kevin D Cashman
    Vitamin D Research Group, School of Food and Nutritional Sciences, and Department of Medicine, University College Cork, Cork, Ireland
    Scand J Clin Lab Invest Suppl 243:136-43. 2012
    ..Finally, it also overviews how the dietary reference intervals for vitamin D may be applied, and especially in terms of assessing the adequacy of vitamin D intake in populations...
  9. ncbi request reprint Diet, nutrition, and bone health
    Kevin D Cashman
    Department of Food and Nutritional Sciences and Department of Medicine, University College Cork, Cork, Ireland
    J Nutr 137:2507S-2512S. 2007
    ..It also briefly considers some of the recent findings that highlight the importance of some dietary factors for bone health in childhood and adolescence...
  10. ncbi request reprint Low vitamin D status adversely affects bone health parameters in adolescents
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Western Road, Cork, Ireland
    Am J Clin Nutr 87:1039-44. 2008
    ..The effects of subclinical vitamin D deficiency on bone mineral density (BMD) and bone turnover in adolescents, especially in boys, are unclear...
  11. ncbi request reprint Optimal nutrition: calcium, magnesium and phosphorus
    K D Cashman
    Department of Nutrition, University College, Cork, Republic of Ireland
    Proc Nutr Soc 58:477-87. 1999
    ..g. balance data. For Ca, there has been interest in using maximal Ca retention, which is based on balance data, bone mass measurements and biomarkers of bone turnover as useful functional indicators of the adequacy of Ca intake...
  12. pmc Vitamin D in childhood and adolescence
    Kevin D Cashman
    Department of Food and Nutritional Sciences, Department of Medicine, University College, Cork, Ireland
    Postgrad Med J 83:230-5. 2007
    ..Therefore, consideration of potential corrective strategies to allow children and adolescents to maintain adequate vitamin D status throughout the year, even in the absence of adequate summer sun exposure, is warranted...
  13. ncbi request reprint A prebiotic substance persistently enhances intestinal calcium absorption and increases bone mineralization in young adolescents
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Nutr Rev 64:189-96. 2006
    ....
  14. ncbi request reprint Prevalence of suboptimal vitamin D status in young, adult and elderly Irish subjects
    T R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Ir Med J 99:48-9. 2006
    ..These findings show that inadequate vitamin D status is quite common in healthy Irish subjects, especially and notably so in young girls and more elderly women...
  15. ncbi request reprint Vitamin K status may be an important determinant of childhood bone health
    Kevin D Cashman
    Department of Food and Nutritional Sciences and the Department of Medicine, University College, Cork, Ireland
    Nutr Rev 63:284-9. 2005
    ..There is a need for randomized phylloquinone supplementation trials to better understand the role of vitamin K on bone acquisition in growing children...
  16. doi request reprint Altered bone metabolism in inflammatory disease: role for nutrition
    Kevin D Cashman
    Department of Food and Nutritional Sciences and Department of Medicine, University College, Cork, Republic of Ireland
    Proc Nutr Soc 67:196-205. 2008
    ..The present review will consider these issues, particularly in the context of inflammatory bowel disease, coeliac disease and atherosclerosis...
  17. doi request reprint Does high vitamin K1 intake protect against bone loss in later life?
    Kevin D Cashman
    University College Cork, Cork, Ireland
    Nutr Rev 66:532-8. 2008
    ..These two studies add to the evidence-base but cast some doubt on the benefits of high vitamin K(1) intake on bone health in later life...
  18. doi request reprint Estimation of the dietary requirement for vitamin D in healthy adults
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Am J Clin Nutr 88:1535-42. 2008
    ..Knowledge gaps have contributed to considerable variation among international dietary recommendations for vitamin D...
  19. ncbi request reprint No effect of copper supplementation on biochemical markers of bone metabolism in healthy young adult females despite apparently improved copper status
    K D Cashman
    Department of Nutrition, University College, Cork, Ireland
    Eur J Clin Nutr 55:525-31. 2001
    ..To investigate the effects of increasing Cu intakes, above the usual dietary intake, on biomarkers of bone metabolism in healthy young adult females (aged 21-28 y) over a 4 week period...
  20. ncbi request reprint Calcium intake, calcium bioavailability and bone health
    K D Cashman
    Nutritional Sciences, Department of Food Science, Food Technology and Nutrition, University College, Cork, Ireland
    Br J Nutr 87:S169-77. 2002
    ..This approach may be of particular value in individuals who fail to achieve the dietary recommended level of Ca...
  21. ncbi request reprint Homocysteine and osteoporotic fracture risk: a potential role for B vitamins
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Nutr Rev 63:29-36. 2005
    ..These vitamins are involved in the metabolism and clearance of homocysteine, and thus may have a protective effect against osteoporotic fracture risk...
  22. ncbi request reprint Prebiotics and calcium bioavailability
    Kevin Cashman
    Department of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Curr Issues Intest Microbiol 4:21-32. 2003
    ..The review will also try to highlight future areas of research that may help in the evaluation of prebiotics as potential ingredients for functional foods aimed at enhancing calcium bioavailability and protecting against osteoporosis...
  23. doi request reprint Estimation of the dietary requirement for vitamin D in healthy adolescent white girls
    Kevin D Cashman
    School of Food and Nutritional Sciences, Department of Medicine, University College Cork, Cork, Ireland
    Am J Clin Nutr 93:549-55. 2011
    ..Knowledge gaps have contributed to considerable variation (between 0 and 15 μg/d) in international dietary recommendations for vitamin D in adolescents...
  24. ncbi request reprint Is nutrition an aetiological factor for inflammatory bowel disease?
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Gastroenterol Hepatol 15:607-13. 2003
    ..In addition, it investigates the possible role of infant feeding practices in the development of IBD...
  25. ncbi request reprint Determinants of vitamin D status in adult Crohn's disease patients, with particular emphasis on supplemental vitamin D use
    J Gilman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 60:889-96. 2006
    ..To investigate determinants (pathophysiologic and physiologic, behavioural and lifestyle) of vitamin D status in Irish Crohn's disease (CD) patients...
  26. ncbi request reprint Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men
    L Doyle
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 59:432-40. 2005
    ..Conjugated linoleic acid (CLA) has been shown to positively influence calcium and bone metabolism in experimental animals and cells in culture, but there are limited human data available...
  27. ncbi request reprint The relationship between nutrient intake and cognitive performance in people at risk of dementia
    R Salerno-Kennedy
    Department of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Ir J Med Sci 176:193-8. 2007
    ..There is evidence of a link between nutrient intake and cognitive impairment and decline in old age. There has been no study of nutrient intake in Irish subjects at risk of dementia...
  28. ncbi request reprint Olfactory function in people with genetic risk of dementia
    R Salerno-Kennedy
    Dept of Food and Nutritional Sciences, University College, Cork
    Ir J Med Sci 174:46-50. 2005
    ..For example, olfactory dysfunction is among the first signs of Alzheimer's disease. There has been no study of olfactory function in Irish subjects at risk of dementia...
  29. doi request reprint Vitamin D status and parathyroid hormone relationship in adolescents and its association with bone health parameters: analysis of the Northern Ireland Young Heart's Project
    T R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Osteoporos Int 21:695-700. 2010
    ..In boys, there was no plateau in PTH concentrations as 25(OH)D concentration increased. A 25(OH)D threshold of 60 nmol/l appears to have implications for bone health outcomes in both girls and boys...
  30. ncbi request reprint Vitamin D intake and status in Irish elderly women and adolescent girls
    D McCarthy
    Dept of Food and Nutritional Sciences, University College, Cork, Ireland
    Ir J Med Sci 175:14-20. 2006
    ..To assess vitamin D status during summer and winter in Irish girls and elderly women, and to estimate vitamin D intake in these two age-groups...
  31. ncbi request reprint Seasonality of vitamin D status and bone turnover in patients with Crohn's disease
    D McCarthy
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Aliment Pharmacol Ther 21:1073-83. 2005
    ..While winter-time vitamin D deficiency has been well-documented in Crohn's disease patients, less is known about vitamin D status during summertime and whether a seasonal variation exists in bone turnover...
  32. ncbi request reprint Selenium intakes in 18-64-y-old Irish adults
    J Murphy
    Nutritional Sciences, Department of Food Science, Food Technology and Nutrition, University College, Cork, Ireland
    Eur J Clin Nutr 56:402-8. 2002
    ..To measure the intake of selenium (Se) and the contribution of different food groups to Se intake in adults aged 18-64 y in Ireland. The adequacy of Se intake in the population is also assessed...
  33. ncbi request reprint Vitamin D intake and status in Irish postmenopausal women
    T Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 59:404-10. 2005
    ..The objective of this study was to assess vitamin D status during late-summer and late-winter/early-spring in postmenopausal Irish women, and whether it was influenced by vitamin D-containing supplement use...
  34. ncbi request reprint Effect of a high-protein, high-salt diet on calcium and bone metabolism in postmenopausal women stratified by hormone replacement therapy use
    M Harrington
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 58:1436-9. 2004
    ..003) in the -HRT group, it had no effect in the +HRT group. It appears that postmenopausal HRT use attenuates the increase in a marker of bone resorption associated with a calciuric diet...
  35. ncbi request reprint The effect of conjugated linoleic acid on calcium absorption and bone metabolism and composition in adult ovariectomised rats
    O Kelly
    Department of Food and Nutritional Sciences, University College, Western Road, Cork, Ireland
    Prostaglandins Leukot Essent Fatty Acids 71:295-301. 2004
    ..001) lowered by CLA supplementation with 5 and 10, but not 2.5 g/kg diet in OVX rats. In conclusion, CLA supplementation appeared to reduce the rate of bone resorption in adult OVX rats...
  36. ncbi request reprint Prevalence of suboptimal vitamin D status during pregnancy
    M N O'Riordan
    Department of Food and Nutritional Sciences, University College, Cork University Maternity Hospital, Cork
    Ir Med J 101:240, 242-3. 2008
    ..These findings show that inadequate vitamin D status is common in Irish pregnant women...
  37. ncbi request reprint The effect of calcium intake on bone composition and bone resorption in the young growing rat
    A Creedon
    Nutritional Sciences, Department of Food Science, Food Technology and Nutrition, University College, Cork, Republic of Ireland
    Br J Nutr 86:453-9. 2001
    ....
  38. ncbi request reprint The relationship between the zinc nutritive status and biochemical markers of bone turnover in older European adults: the ZENITH study
    T Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Clin Nutr 59:S73-8. 2005
    ..To investigate the relationship between indices of zinc nutritive status and biochemical markers of bone turnover in older adult European subjects...
  39. ncbi request reprint Altered levels of biochemical indices of bone turnover and bone-related vitamins in patients with Crohn's disease and ulcerative colitis
    J Gilman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Aliment Pharmacol Ther 23:1007-16. 2006
    ..The pathogenesis of inflammatory bowel disease-associated osteopenia may be related to pathological rates of bone turnover; however, the literature shows mixed results...
  40. ncbi request reprint An assessment of genetic markers as predictors of bone turnover in healthy adults
    D Sheehan
    Department of Nutrition, University College, Cork, Ireland
    J Endocrinol Invest 24:236-45. 2001
    ....
  41. ncbi request reprint Selenium status of Irish adults: evidence of insufficiency
    J Murphy
    Department of Food Science, Food Technology and Nutrition, University College, Cork, Ireland
    Ir J Med Sci 171:81-4. 2002
    ..Selenium status depends on adequate selenium in the diet. A relatively high proportion of Irish adults (17% men; 46% women) have an inadequate dietary intake...
  42. ncbi request reprint The effect of conjugated linoleic acid on transepithelial calcium transport and mediators of paracellular permeability in human intestinal-like Caco-2 cells
    C Jewell
    Department of Food and Nutritional Sciences, University College, Western Road, Cork, Ireland
    Prostaglandins Leukot Essent Fatty Acids 72:163-71. 2005
    ..001) by exposure of Caco-2 cells to both isomers of CLA, an effect which appeared to be related to altered localization of zona occludens 1 (a tight junction protein)...
  43. ncbi request reprint Calcium and vitamin D
    Kevin D Cashman
    Department of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Novartis Found Symp 282:123-38; discussion 138-42, 212-8. 2007
    ..It will also focus on the issues of efficacy as well as safety considerations of supplements...
  44. ncbi request reprint A preliminary assessment of vitamin K1 intakes and serum undercarboxylated osteocalcin levels in 11-13 year old Irish girls
    Aoife Collins
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Int J Vitam Nutr Res 76:385-90. 2006
    ..538; p = 0.026). The data indicate that large-scale studies to examine relationships between vitamin K1 (and green vegetable) intakes and bone growth and development in adolescents are warranted...
  45. ncbi request reprint Impact of genetic variation on metabolic response of bone to diet
    Siobhan Cusack
    Department of Food and Nutritional Sciences, University College, Cork, Republic of Ireland
    Proc Nutr Soc 62:901-12. 2003
    ..The aim of the present review is to critically evaluate current knowledge relating to candidate genes for osteoporosis, with particular emphasis on their interaction with nutrients and dietary factors in determining bone health...
  46. ncbi request reprint Inadequate dietary calcium and vitamin D intakes in renal-transplant recipients in Ireland
    Irene T Lynch
    Department of Clinical Nutrition, Cork University Hospital, Cork, Ireland
    J Ren Nutr 17:408-15. 2007
    ..To quantify the dietary calcium and vitamin D intake in adult renal-transplant recipients attending at a large teaching hospital in Ireland for follow-up...
  47. pmc Nutrition and bone health projects funded by the UK Food Standards Agency: have they helped to inform public health policy?
    Margaret Ashwell
    Ashwell Associates Europe Ltd, Ashwell, Hertfordshire SG7 5PZ and Oxford Brookes University, Oxford OX3 0BP, UK
    Br J Nutr 99:198-205. 2008
    ..The major research gap identified was the need to investigate vitamin D status to define deficiency, insufficiency and depletion across age and ethnic groups in relation to bone health...
  48. ncbi request reprint The effect of a high-protein, high-sodium diet on calcium and bone metabolism in postmenopausal women and its interaction with vitamin D receptor genotype
    Mary Harrington
    Department of Food and Nutritional Sciences, Cork, Republic of Ireland
    Br J Nutr 91:41-51. 2004
    ..It is concluded that the Na- and protein-induced urinary Ca loss is compensated for by increased bone resorption and that this response may be influenced by VDR genotype...
  49. ncbi request reprint Influence of moderate energy restriction and seafood consumption on bone turnover in overweight young adults
    Alice J Lucey
    Department of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Am J Clin Nutr 87:1045-52. 2008
    ..However, moderate energy restriction aimed at lowering body weight may promote bone turnover and bone loss. Inclusion of fish or fish oils in a weight-loss diet may attenuate these adverse skeletal effects...
  50. doi request reprint Sodium and bone health: impact of moderately high and low salt intakes on calcium metabolism in postmenopausal women
    Birgit Teucher
    Medical Research Council, Human Nutrition Research, Cambridge, United Kingdom
    J Bone Miner Res 23:1477-85. 2008
    ....
  51. ncbi request reprint Seasonal changes in vitamin D status and bone turnover in healthy Irish postmenopausal women
    Tom R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Int J Vitam Nutr Res 77:320-5. 2007
    ..To examine the effect of season on biochemical markers of bone turnover in 51-to 75-year-old Irish women and to investigate whether such changes are related to vitamin D status...
  52. ncbi request reprint The effect of bovine whey protein on ectopic bone formation in young growing rats
    Owen Kelly
    Department of Medicine, University College, Cork, Republic of Ireland
    Br J Nutr 90:557-64. 2003
    ..This effect may be mediated by an increased synthesis of IGF-I in growing bone. The effect of WP on bone formation warrants further investigation...
  53. ncbi request reprint The effect of polyunsaturated fatty acids, including conjugated linoleic acid, on calcium absorption and bone metabolism and composition in young growing rats
    Owen Kelly
    Department of Food and Nutritional Sciences, University College, Cork, Republic of Ireland
    Br J Nutr 90:743-50. 2003
    ..In conclusion, CLA supplementation over 8 weeks appeared to enhance Ca absorption in young growing rats fed an n-3 PUFA-rich diet, but had no measurable effect on bone metabolism or bone mass over this time frame...
  54. ncbi request reprint The effect of oestrogen and dietary phyto-oestrogens on transepithelial calcium transport in human intestinal-like Caco-2 cells
    Alice A Cotter
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Br J Nutr 89:755-65. 2003
    ..In conclusion, PO at high luminal concentrations either had no effect or reduced Ca absorption in Caco-2 cells, dependent on oestrogen status. The effect of lower concentrations of these compounds needs to be investigated...
  55. ncbi request reprint The effect of nutrient profiles of the Dietary Approaches to Stop Hypertension (DASH) diets on blood pressure and bone metabolism and composition in normotensive and hypertensive rats
    Lorna Doyle
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Br J Nutr 89:713-24. 2003
    ..However, as blood pressure was unaffected by this diet, the mechanism by which it reduced bone turnover requires further investigation...
  56. ncbi request reprint High salt intake appears to increase bone resorption in postmenopausal women but high potassium intake ameliorates this adverse effect
    Mary Harrington
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Nutr Rev 61:179-83. 2003
    ..These findings may have implications for the development of dietary guidelines for osteoporosis prevention...
  57. ncbi request reprint The DASH diet may have beneficial effects on bone health
    Lorna Doyle
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Nutr Rev 62:215-20. 2004
    ..This DASH diet-induced reduction in bone turnover, if sustained, may improve bone mineral status...
  58. ncbi request reprint The effect of two dietary and a synthetic phytoestrogen on transepithelial calcium transport in human intestinal-like Caco-2 cells
    Alice A Cotter
    Dept of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Nutr 44:72-8. 2005
    ..While PEs act directly on bone cells, their protective effect on bone may be partly due to their ability to enhance Ca absorption...
  59. ncbi request reprint Vitamin D status of 51-75-year-old Irish women: its determinants and impact on biochemical indices of bone turnover
    Tom R Hill
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Public Health Nutr 9:225-33. 2006
    ..In addition, the determinants of wintertime serum 25-hydroxyvitamin D (25OH-D) levels in these women were investigated...
  60. ncbi request reprint Phylloquinone (vitamin K1) intakes and serum undercarboxylated osteocalcin levels in Irish postmenopausal women
    Aoife Collins
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Br J Nutr 95:982-8. 2006
    ..04). On the basis of comparisons with both UK recommendations and US Adequate Intakes for phylloquinone, the habitual intakes of phylloquinone in a high proportion of Irish postmenopausal women may not be adequate...
  61. ncbi request reprint Phylloquinone (vitamin K1) intakes and food sources in 18-64-year-old Irish adults
    Paula Duggan
    Department of Food and Nutritional Sciences, University College Cork, Cork, Republic of Ireland
    Br J Nutr 92:151-8. 2004
    ..The present study shows that habitual phylloquinone intakes in Irish adults are low, which may have implications for bone health...
  62. ncbi request reprint Relationship between dementia and nutrition-related factors and disorders: an overview
    Rossana Salerno-Kennedy
    Department of Food and Nutritional Science, University College, Cork, Ireland
    Int J Vitam Nutr Res 75:83-95. 2005
    ..These factors can be present for a long time before cognitive impairment becomes evident, therefore they could be potentially detected and corrected in a timely manner...
  63. ncbi request reprint A positive dose-response effect of vitamin D supplementation on site-specific bone mineral augmentation in adolescent girls: a double-blinded randomized placebo-controlled 1-year intervention
    Heli T Viljakainen
    Calcium Research Unit, Department of Applied Chemistry and Microbiology, University of Helsinki, Helsinki, Finland
    J Bone Miner Res 21:836-44. 2006
    ..Supplementation decreased the urinary excretion of resorption markers, but had no impact on formation markers...
  64. ncbi request reprint The role of nutrition in dementia: an overview
    Rossana Salerno-Kennedy
    Department of Food and Nutritional Sciences and Department of Medicine, Biosciences Institute, University College Cork, Cork, Ireland
    J Br Menopause Soc 12:44-8. 2006
    ..This review provides a brief overview of this topic...
  65. ncbi request reprint Vitamin D and estrogen receptor-alpha genotype and indices of bone mass and bone turnover in Danish girls
    Siobhan Cusack
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    J Bone Miner Metab 24:329-36. 2006
    ..These findings suggest that the rate of bone resorption was influenced by ERalpha genotypes, even though these biochemical differences were not evident in bone mass indices...
  66. ncbi request reprint Personalised nutrition: status and perspectives
    Hans Georg Joost
    German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, Nuthetal, Germany
    Br J Nutr 98:26-31. 2007
    ..These issues need to be addressed before genotyping can become an acceptable method to guide nutritional recommendations...
  67. ncbi request reprint Serum percentage undercarboxylated osteocalcin, a sensitive measure of vitamin K status, and its relationship to bone health indices in Danish girls
    Eibhlís O'Connor
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Br J Nutr 97:661-6. 2007
    ..There is a need for well-designed, randomized phylloquinone supplementation trials in children and adolescents to confirm epidemiological findings of an association between vitamin K status and bone health...
  68. ncbi request reprint Effect of phylloquinone supplementation on biochemical markers of vitamin K status and bone turnover in postmenopausal women
    Susanne Bugel
    Department of Human Nutrition Centre for Advanced Food Studies, The Royal Veterinary and Agricultural University, Rolighedsvej 30, DK 1958 Frederiksberg C, Denmark
    Br J Nutr 97:373-80. 2007
    ..In conclusion, while daily supplementation with 200 and 500 microg phylloquinone/d for 6 weeks increased vitamin K status in postmenopausal women, it had no effect on bone turnover...
  69. ncbi request reprint Potential applications of breath isoprene as a biomarker in modern medicine: a concise overview
    Rossana Salerno-Kennedy
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Wien Klin Wochenschr 117:180-6. 2005
    ..In the present work, we aim to give a concise overview of breath isoprene, its measurement techniques, problems concerning its physiological meaning, and potential applications as a non-invasive biomarker in modern medicine...
  70. ncbi request reprint The effect of probiotic bacteria on transepithelial calcium transport and calcium uptake in human intestinal-like Caco-2 cells
    Jennifer Gilman
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Curr Issues Intest Microbiol 7:1-5. 2006
    ..In conclusion, the findings of this study which suggest that bacteria can enhance intestinal calcium uptake, if not calcium transport, highlights the need to undertake further studies in this, to date, vastly underinvestigated area...
  71. ncbi request reprint A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls - a cross-sectional study
    Heli T Viljakainen
    Calcium Research Unit, Department of Applied Chemistry and Microbiology, University of Helsinki, Helsinki, Finland
    Br J Nutr 96:124-30. 2006
    ..In addition, the seasonal rhythm contributed 7.0-7.6 % difference in the BMD of lumbar vertebrae and left femur in early puberty girls. This variation should be avoided since it could hamper peak bone mass attainment...
  72. ncbi request reprint Vitamin K status in patients with Crohn's disease and relationship to bone turnover
    Paula Duggan
    Department of Food and Nutritional Sciences, and Alimentary Pharmabiotic Centre, University College, Cork, Ireland
    Am J Gastroenterol 99:2178-85. 2004
    ..There is a high prevalence of osteopenia among patients with Crohn's disease (CD). There is some evidence that a deficiency of certain bone-active nutrients (including vitamins K and D) may have a partial role in this bone loss...
  73. ncbi request reprint Long-term moderate zinc supplementation increases exchangeable zinc pool masses in late-middle-aged men: the Zenith Study
    Christine Feillet-Coudray
    Centre de Recherche en Nutrition Humaine d Auvergne, Unite Maladies Metaboliques et Micronutriments, INRA, St Genes Champanelle, France
    Am J Clin Nutr 82:103-10. 2005
    ..Zinc supplementation may be beneficial for health. Assessing exchangeable zinc pools may be a useful approach to evaluate zinc status...
  74. ncbi request reprint The effect of conjugated linoleic acid and medium-chain fatty acids on transepithelial calcium transport in human intestinal-like Caco-2 cells
    Christopher Jewell
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Br J Nutr 89:639-47. 2003
    ..01, by about 1.5-fold relative to the control value) by exposure to 10:0, 12:0 and trans-10,cis-12 CLA for 22 d, suggesting that these non-esterified fatty acids could potentially enhance Ca absorption in vivo...
  75. ncbi request reprint Effect of 17beta-oestradiol on transepithelial calcium transport in human intestinal-like Caco-2 cells and its interactions with 1,25-dihydroxycholecalciferol and 9-cis retinoic acid
    A A Cotter
    Dept of Food and Nutritional Sciences, University College, Cork, Ireland
    Eur J Nutr 45:234-41. 2006
    ..Since oestrogen also increases retinol levels, this may influence Ca absorption...
  76. ncbi request reprint Conjugated linoleic acid enhances transepithelial calcium transport in human intestinal-like Caco-2 cells: an insight into molecular changes
    Eileen F Murphy
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Prostaglandins Leukot Essent Fatty Acids 74:295-301. 2006
    ..The mechanism by which CLA enhances transcellular Ca transport remains unclear...
  77. ncbi request reprint Genistein appears to prevent early postmenopausal bone loss as effectively as hormone replacement therapy
    Alice Cotter
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    Nutr Rev 61:346-51. 2003
    ..These findings may have implications for the development of diet-based strategies aimed at osteoporosis prevention...
  78. ncbi request reprint Lack of dose-responsive effect of dietary phyto-oestrogens on transepithelial calcium transport in human intestinal-like Caco-2 cells
    Alice A Cotter
    Department of Food and Nutritional Sciences, University College, Republic of Ireland
    Br J Nutr 91:5-9. 2004
    ....
  79. ncbi request reprint The effect of marine oil-derived n-3 fatty acids on transepithelial calcium transport in Caco-2 cell models of healthy and inflamed intestines
    Jennifer Gilman
    Department of Food and Nutritional Sciences, University College, Cork, Republic of Ireland
    Br J Nutr 97:281-8. 2007
    ..In conclusion, the present in vitro findings highlight the need to investigate the effect of marine oil-based n-3 fatty acids on Ca absorption in vivo in studies of healthy human subjects as well as of Crohn's disease patients...
  80. ncbi request reprint Conjugated linoleic acid alters global gene expression in human intestinal-like Caco-2 cells in an isomer-specific manner
    Eileen F Murphy
    Department of Food and Nutritional Sciences, University College, Cork, Ireland
    J Nutr 137:2359-65. 2007
    ..These may help our mechanistic understanding of the role of CLA in promoting gut function and health...