MARTIN D CAFFREY

Summary

Affiliation: University of Limerick
Country: Ireland

Publications

  1. pmc The Membrane Protein Data Bank
    P Raman
    Biophysics Program, The Ohio State University, Columbus, Ohio 43210, USA
    Cell Mol Life Sci 63:36-51. 2006
  2. doi request reprint Crystallizing membrane proteins for structure determination: use of lipidic mesophases
    Martin Caffrey
    University of Limerick, Limerick, Ireland
    Annu Rev Biophys 38:29-51. 2009
  3. pmc Crystallizing membrane proteins using lipidic mesophases
    Martin Caffrey
    Membrane Structural and Functional Biology Group, University of Limerick, Limerick, Ireland
    Nat Protoc 4:706-31. 2009

Research Grants

Collaborators

  • P Raman
  • V Cherezov

Detail Information

Publications3

  1. pmc The Membrane Protein Data Bank
    P Raman
    Biophysics Program, The Ohio State University, Columbus, Ohio 43210, USA
    Cell Mol Life Sci 63:36-51. 2006
    ..A summary of the statistics as applied to entries in the MPDB is presented. The data suggest conditions appropriate for crystallization trials with novel membrane proteins...
  2. doi request reprint Crystallizing membrane proteins for structure determination: use of lipidic mesophases
    Martin Caffrey
    University of Limerick, Limerick, Ireland
    Annu Rev Biophys 38:29-51. 2009
    ..A hypothesis for how the method works at the molecular level and experimental evidence in support of the proposal are reviewed here. The latest advances, successes, and challenges associated with the method are described...
  3. pmc Crystallizing membrane proteins using lipidic mesophases
    Martin Caffrey
    Membrane Structural and Functional Biology Group, University of Limerick, Limerick, Ireland
    Nat Protoc 4:706-31. 2009
    ..Methods for harvesting microcrystals are also described. The time required to prepare the protein-loaded mesophase and to set up a crystallization plate manually is about 1 h...

Research Grants14

  1. MEMBRANE PROTEIN STRUCTURE : USE OF LIPIDIC MESOPHASES
    Martin Caffrey; Fiscal Year: 2004
    ..The results of these studies, together with an analysis in detail of the crystal/lipid interface will then be used in attempts at rational crystallization of the previously uncrystallized photosystem II from Chlamydomonas. ..
  2. INTERMEDIATES AND TRANSBILAYER PEPTIDES
    Martin Caffrey; Fiscal Year: 2001
    ..Such activity is consistent with Dr. Caffrey's hypothesis. ..
  3. Membrane Proteins. Crystallogenesis/X-ray Structure(RMI)
    Martin Caffrey; Fiscal Year: 2007
    ..Success in obtaining crystals, and ultimately the atomic structure of membrane proteins, will enhance our understanding of some of the most fundamental processes underlying cellular function that are integral to human health. ..
  4. Membrane Proteins, Crystallogenesis and X-ray Structure
    Martin Caffrey; Fiscal Year: 2009
    ..Success in obtaining crystals, and ultimately the atomic structure of membrane proteins, will enhance our understanding of some of the most fundamental processes underlying cellular function that are integral to human health. ..