Marie Semon

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. pmc Unexpected observations after mapping LongSAGE tags to the human genome
    Celine Keime
    Universite de Lyon, Lyon, France
    BMC Bioinformatics 8:154. 2007
  2. ncbi request reprint Evolutionary origin and maintenance of coexpressed gene clusters in mammals
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Mol Biol Evol 23:1715-23. 2006
  3. ncbi request reprint No evidence for tissue-specific adaptation of synonymous codon usage in humans
    Marie Semon
    Laboratoire de Biométrie et Biologie Évolutive UMR 5558, Centre National de la Recherche Scientifique, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Mol Biol Evol 23:523-9. 2006
  4. ncbi request reprint Relationship between gene expression and GC-content in mammals: statistical significance and biological relevance
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 16 rue Raphael Dubois, 69622 Villeurbanne Cedex, France
    Hum Mol Genet 14:421-7. 2005
  5. ncbi request reprint Evidence that functional transcription units cover at least half of the human genome
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 16 rue Raphael Dubois, 69622 Villeurbanne Cedex, France
    Trends Genet 20:229-32. 2004
  6. ncbi request reprint Influence of the transposable element neighborhood on human gene expression in normal and tumor tissues
    Emmanuelle Lerat
    Universite de Lyon, Universite Lyon 1, CNRS, UMR 5558, Laboratoire de Biometrie et Biologie Evolutive, 43 Boulevard du 11 Novembre 1918, Villeurbanne F 69622, France
    Gene 396:303-11. 2007
  7. pmc Vanishing GC-rich isochores in mammalian genomes
    Laurent Duret
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 69622 Villeurbanne Cedex, France
    Genetics 162:1837-47. 2002
  8. doi request reprint Programmed genome rearrangements: in lampreys, all cells are not equal
    Marie Semon
    Institut de Génomique Fonctionnelle de Lyon UMR 5242 du CNRS, Ecole Normale Superieure de Lyon, Universite Claude Bernard Lyon 1, Universite de Lyon, 46 allee d Italie, 69364 Lyon Cedex 07, France
    Curr Biol 22:R641-3. 2012

Collaborators

Detail Information

Publications8

  1. pmc Unexpected observations after mapping LongSAGE tags to the human genome
    Celine Keime
    Universite de Lyon, Lyon, France
    BMC Bioinformatics 8:154. 2007
    ..Here we used this property to study the position of human LongSAGE tags obtained from all public libraries. We focused mainly on tags that do not map to known transcripts...
  2. ncbi request reprint Evolutionary origin and maintenance of coexpressed gene clusters in mammals
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Mol Biol Evol 23:1715-23. 2006
    ..In contradiction, we find that most of these clusters contain only 2 genes whose coexpression may be due to transcriptional read-through or the activity of bidirectional promoters...
  3. ncbi request reprint No evidence for tissue-specific adaptation of synonymous codon usage in humans
    Marie Semon
    Laboratoire de Biométrie et Biologie Évolutive UMR 5558, Centre National de la Recherche Scientifique, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Mol Biol Evol 23:523-9. 2006
    ..This demonstrates that variations of synonymous codon usage between tissue-specific genes expressed in different tissues are due to regional variations of substitution patterns and not to translational selection...
  4. ncbi request reprint Relationship between gene expression and GC-content in mammals: statistical significance and biological relevance
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 16 rue Raphael Dubois, 69622 Villeurbanne Cedex, France
    Hum Mol Genet 14:421-7. 2005
    ..We show here that using gene windows artificially enhances the correlation. The assertion that the expression of a given gene depends on the GC-content of the region where it is located is therefore not supported by the data...
  5. ncbi request reprint Evidence that functional transcription units cover at least half of the human genome
    Marie Semon
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 16 rue Raphael Dubois, 69622 Villeurbanne Cedex, France
    Trends Genet 20:229-32. 2004
    ..Our results indicate that FTUs constitute at least 50% of the genome and that approximately one-third of these transcripts apparently do not encode proteins...
  6. ncbi request reprint Influence of the transposable element neighborhood on human gene expression in normal and tumor tissues
    Emmanuelle Lerat
    Universite de Lyon, Universite Lyon 1, CNRS, UMR 5558, Laboratoire de Biometrie et Biologie Evolutive, 43 Boulevard du 11 Novembre 1918, Villeurbanne F 69622, France
    Gene 396:303-11. 2007
    ..This deregulation increases with the number of SINE copies in the gene vicinity. This suggests that SINE elements might contribute to the cascade of gene deregulation in cancer cells...
  7. pmc Vanishing GC-rich isochores in mammalian genomes
    Laurent Duret
    Laboratoire de Biometrie et Biologie Evolutive, UMR CNRS 5558 Université Claude Bernard Lyon 1, 69622 Villeurbanne Cedex, France
    Genetics 162:1837-47. 2002
    ..We propose a model based on the biased gene conversion hypothesis that accounts for the origin of GC-rich isochores in the ancestral amniote genome and for their decline in present-day mammals...
  8. doi request reprint Programmed genome rearrangements: in lampreys, all cells are not equal
    Marie Semon
    Institut de Génomique Fonctionnelle de Lyon UMR 5242 du CNRS, Ecole Normale Superieure de Lyon, Universite Claude Bernard Lyon 1, Universite de Lyon, 46 allee d Italie, 69364 Lyon Cedex 07, France
    Curr Biol 22:R641-3. 2012
    ..How can organisms silence deleterious gene loci? A recent study has shed light on a very brute mechanism in a jawless vertebrate: the irreversible deletion of massive chunks of genomic DNA...