Ricardo Segurado

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. ncbi request reprint Confirmation of association between autism and the mitochondrial aspartate/glutamate carrier SLC25A12 gene on chromosome 2q31
    Ricardo Segurado
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Psychiatry 162:2182-4. 2005
  2. pmc Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder
    Ziarih Hawi
    Department of Psychiatry and Genetics, Trinity College, Dublin, Ireland
    Am J Hum Genet 77:958-65. 2005
  3. pmc A genome-wide scan for common alleles affecting risk for autism
    Richard Anney
    Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland
    Hum Mol Genet 19:4072-82. 2010
  4. pmc Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder
    Ricardo Segurado
    Neuropsychiatric Genetics Unit, Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 73:49-62. 2003
  5. ncbi request reprint Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    Marian L Hamshere
    Department of Psychological Medicine, School of Medicine, Cardiff University, Wales
    Arch Gen Psychiatry 62:1081-8. 2005
  6. pmc Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis
    Douglas F Levinson
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, 3535 Market Street, Room 4006, Philadelphia, PA 19104 3309, USA
    Am J Hum Genet 73:17-33. 2003
  7. ncbi request reprint Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
    Andrew Grupe
    Celera Diagnostics, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
    Hum Mol Genet 16:865-73. 2007
  8. ncbi request reprint Association analysis of AKT1 and schizophrenia in a UK case control sample
    Nadine Norton
    Department of Psychological Medicine, Wales School of Medicine, Henry Wellcome Building, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Schizophr Res 93:58-65. 2007
  9. ncbi request reprint Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16
    Ian Jones
    Department of Psychological Medicine, Henry Wellcome Building, Wales School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN UK
    Am J Psychiatry 164:1099-104. 2007
  10. ncbi request reprint Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease
    Yonghong Li
    Celera, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
    Hum Mol Genet 17:759-67. 2008

Detail Information

Publications11

  1. ncbi request reprint Confirmation of association between autism and the mitochondrial aspartate/glutamate carrier SLC25A12 gene on chromosome 2q31
    Ricardo Segurado
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Psychiatry 162:2182-4. 2005
    ..4 and 4.8. The authors' goal was to investigate this association with autism in Irish affected child-parent trios because replication in an independent sample is essential in the validation of such potentially important findings...
  2. pmc Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder
    Ziarih Hawi
    Department of Psychiatry and Genetics, Trinity College, Dublin, Ireland
    Am J Hum Genet 77:958-65. 2005
    ..Possible reasons for this preferential transmission include imprinting and ascertainment bias, although results of further analyses show that the latter is unlikely...
  3. pmc A genome-wide scan for common alleles affecting risk for autism
    Richard Anney
    Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland
    Hum Mol Genet 19:4072-82. 2010
    ..Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C...
  4. pmc Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder
    Ricardo Segurado
    Neuropsychiatric Genetics Unit, Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 73:49-62. 2003
    ..We note that meta-analysis can sometimes provide support for linkage but cannot disprove linkage in any candidate region...
  5. ncbi request reprint Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    Marian L Hamshere
    Department of Psychological Medicine, School of Medicine, Cardiff University, Wales
    Arch Gen Psychiatry 62:1081-8. 2005
    ..However, twin data suggest that, in addition to genes with specificity for these phenotypes, there exist genes that simultaneously influence susceptibility to schizophrenia, bipolar disorder, and schizoaffective disorder...
  6. pmc Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis
    Douglas F Levinson
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, 3535 Market Street, Room 4006, Philadelphia, PA 19104 3309, USA
    Am J Hum Genet 73:17-33. 2003
    ..The results suggest that GSMA can detect linkage across multiple genome scans...
  7. ncbi request reprint Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants
    Andrew Grupe
    Celera Diagnostics, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
    Hum Mol Genet 16:865-73. 2007
    ..This is a missense mutation in the galanin-like peptide precursor gene (P = 0.00005, OR = 1.2, false positive rate = 0.87)...
  8. ncbi request reprint Association analysis of AKT1 and schizophrenia in a UK case control sample
    Nadine Norton
    Department of Psychological Medicine, Wales School of Medicine, Henry Wellcome Building, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Schizophr Res 93:58-65. 2007
    ..Examination of our own data and those of other groups leads us to conclude that overall, the evidence for association of AKT1 as a susceptibility gene for schizophrenia is weakly positive, but not yet convincing...
  9. ncbi request reprint Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16
    Ian Jones
    Department of Psychological Medicine, Henry Wellcome Building, Wales School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN UK
    Am J Psychiatry 164:1099-104. 2007
    ..The authors conducted a search by systematic whole genome linkage scan for loci influencing vulnerability to bipolar affective puerperal psychosis...
  10. ncbi request reprint Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease
    Yonghong Li
    Celera, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA
    Hum Mol Genet 17:759-67. 2008
    ..These data implicate NEDD9 as a novel susceptibility gene for LOAD and possibly PD...
  11. pmc Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
    Matthew B McQueen
    Harvard School of Public Health, Department of Epidemiology, Boston, MA 02115, USA
    Am J Hum Genet 77:582-95. 2005
    ..Our results establish genomewide significant linkage to BP on chromosomes 6q and 8q, which provides solid information to guide future gene-finding efforts that rely on fine-mapping and association approaches...