A S Perry

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. doi request reprint Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer
    Antoinette S Perry
    Prostate Molecular Oncology, Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Ireland
    Int J Cancer 132:1771-80. 2013
  2. pmc In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer
    A S Perry
    Department of Haematology and Academic Unit of Clinical and Molecular Oncology, Institute of Molecular Medicine, St James s Hospital and Trinity College Dublin, Ireland
    Br J Cancer 96:1587-94. 2007
  3. doi request reprint The epigenome as a therapeutic target in prostate cancer
    Antoinette S Perry
    Prostate Molecular Oncology, Trinity Centre for Health Sciences, St James s Hospital, Dublin 8, Ireland
    Nat Rev Urol 7:668-80. 2010
  4. doi request reprint The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer
    T M Murphy
    Prostate Cancer Research Group, Institute of Molecular Medicine, Trinity College Dublin, Ireland
    Endocr Relat Cancer 15:11-25. 2008

Detail Information

Publications4

  1. doi request reprint Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer
    Antoinette S Perry
    Prostate Molecular Oncology, Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Ireland
    Int J Cancer 132:1771-80. 2013
    ..45, HB = 0.47, and BPH = 0.12). We show that SFRP2 hypermethylation is a common event in prostate cancer. SFRP2 methylation in combination with other epigenetic markers may be a useful biomarker of prostate cancer...
  2. pmc In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer
    A S Perry
    Department of Haematology and Academic Unit of Clinical and Molecular Oncology, Institute of Molecular Medicine, St James s Hospital and Trinity College Dublin, Ireland
    Br J Cancer 96:1587-94. 2007
    ..Evaluation of further relevant genes could contribute towards a methylation signature of this disease...
  3. doi request reprint The epigenome as a therapeutic target in prostate cancer
    Antoinette S Perry
    Prostate Molecular Oncology, Trinity Centre for Health Sciences, St James s Hospital, Dublin 8, Ireland
    Nat Rev Urol 7:668-80. 2010
    ..Reactivation of tumor-suppressor genes by demethylating agents and histone deacetylase inhibitors could be a potential treatment option for patients with advanced disease...
  4. doi request reprint The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer
    T M Murphy
    Prostate Cancer Research Group, Institute of Molecular Medicine, Trinity College Dublin, Ireland
    Endocr Relat Cancer 15:11-25. 2008
    ..We also introduce the concept of an 'apoptotic methylation signature' for prostate cancer and evaluate its potential in a diagnostic, prognostic and therapeutic setting...