Rachel M McLoughlin

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. doi Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort
    R M McLoughlin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Clin Exp Allergy 42:392-404. 2012
  2. doi Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma
    Rachel M McLoughlin
    School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    J Allergy Clin Immunol 127:1097-107; quiz 1108-9. 2011
  3. pmc Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine
    Pádraig J Ross
    Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
    PLoS Pathog 9:e1003264. 2013
  4. pmc Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
    Edel A McNeela
    Adjuvant Research Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    PLoS Pathog 6:e1001191. 2010

Collaborators

Detail Information

Publications4

  1. doi Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort
    R M McLoughlin
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Clin Exp Allergy 42:392-404. 2012
    ..Immunomodulatory T cells are thought to influence development of allergy and asthma, but early life longitudinal data on their phenotype and function are lacking...
  2. doi Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma
    Rachel M McLoughlin
    School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    J Allergy Clin Immunol 127:1097-107; quiz 1108-9. 2011
    ....
  3. pmc Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine
    Pádraig J Ross
    Immune Regulation Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
    PLoS Pathog 9:e1003264. 2013
    ..Our findings demonstrate that alum promotes protective immunity through IL-1β-induced IL-17A production, but also reveal that optimum protection against B. pertussis requires induction of Th1, but not Th2 cells...
  4. pmc Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
    Edel A McNeela
    Adjuvant Research Group, School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    PLoS Pathog 6:e1001191. 2010
    ..Furthermore, NLRP3 was required for protective immunity against respiratory infection with S. pneumoniae. These results add significantly to our understanding of the interactions between PLY and the immune system...