Elaine F Kenny

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. doi request reprint Signalling adaptors used by Toll-like receptors: an update
    Elaine F Kenny
    School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Cytokine 43:342-9. 2008
  2. pmc Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin
    Elaine F Kenny
    Immunology Research Centre, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
    PLoS ONE 8:e74103. 2013
  3. doi request reprint MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3
    Elaine F Kenny
    School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    J Immunol 183:3642-51. 2009
  4. pmc Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15
    Sarah L Doyle
    Immunology Research Centre, Trinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland
    J Biol Chem 288:25066-75. 2013
  5. ncbi request reprint Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins
    Tanya M Watters
    School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Immunol Cell Biol 85:411-9. 2007

Detail Information

Publications5

  1. doi request reprint Signalling adaptors used by Toll-like receptors: an update
    Elaine F Kenny
    School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Cytokine 43:342-9. 2008
    ..These advances confirm the importance for the TIR domain-containing adapters in host defence and inflammation...
  2. pmc Bruton's tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin
    Elaine F Kenny
    Immunology Research Centre, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
    PLoS ONE 8:e74103. 2013
    ..Downstream of BTK we find that calcium acting via calmodulin is required for this process. These data provide new insights into the role of BTK, an important target for autoimmune diseases, in B cell activation. ..
  3. doi request reprint MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3
    Elaine F Kenny
    School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland
    J Immunol 183:3642-51. 2009
    ..An inhibitory role for Mal in TLR3 signaling to JNK was also demonstrated...
  4. pmc Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15
    Sarah L Doyle
    Immunology Research Centre, Trinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland
    J Biol Chem 288:25066-75. 2013
    ..Our study identifies NFκB2 as a target for IKKε in antiviral immunity and describes, for the first time, a role for NFκB2 in the regulation of gene expression in response to viral infection. ..
  5. ncbi request reprint Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins
    Tanya M Watters
    School of Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Immunol Cell Biol 85:411-9. 2007
    ..Furthermore, recent findings regarding the regulation of adaptors provide further insight into the crucial role of the TIR domain in TLR signalling...