M Gill

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. doi request reprint Developmental psychopathology: the role of structural variation in the genome
    Michael Gill
    Department of Psychiatry, Trinity College, Dublin, Ireland
    Dev Psychopathol 24:1319-34. 2012
  2. pmc Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for autism
    Katherine E Tansey
    Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
    Mol Autism 2:3. 2011
  3. pmc The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Behav Brain Funct 4:48. 2008
  4. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligence
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    BMC Psychiatry 11:55. 2011
  5. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Switzerland
    BMC Psychiatry 11:54. 2011
  6. pmc The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
    Anne Farmer
    Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    BMC Psychiatry 4:42. 2004
  7. doi request reprint What have the genomics ever done for the psychoses?
    M Gill
    Neuropsychiatric Genetics Research Group, Department of Psychiatry, School of Medicine, Trinity College Dublin 8, Ireland
    Psychol Med 40:529-40. 2010
  8. ncbi request reprint Presenilin 1 and alpha-1-antichymotrypsin polymorphisms in Down syndrome: no effect on the presence of dementia
    J Tyrrell
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet 88:616-20. 1999
  9. ncbi request reprint Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD
    K Sheehan
    Department of Genetics, Trinity College Dublin, Dublin, Ireland
    Mol Psychiatry 10:944-9. 2005
  10. ncbi request reprint Pseudoautosomal gene: possible association with bipolar males but not with schizophrenia
    Z Hawi
    Department of Psychiatry and Genetics, Trinity College, Dublin, Ireland
    Psychiatr Genet 9:129-34. 1999

Detail Information

Publications37

  1. doi request reprint Developmental psychopathology: the role of structural variation in the genome
    Michael Gill
    Department of Psychiatry, Trinity College, Dublin, Ireland
    Dev Psychopathol 24:1319-34. 2012
    ..It examines likely developments in the knowledge base as well as addressing the clinical implications going forward...
  2. pmc Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for autism
    Katherine E Tansey
    Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
    Mol Autism 2:3. 2011
    ..abstract:..
  3. pmc The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Behav Brain Funct 4:48. 2008
    ..abstract:..
  4. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligence
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
    BMC Psychiatry 11:55. 2011
    ..In particular, to investigate the influence of age, gender, family status (proband vs. sibling), informant, and centres on sample homogeneity in psychopathological measures...
  5. pmc The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns
    Ueli C Muller
    Department of Child and Adolescent Psychiatry, University of Zurich, Switzerland
    BMC Psychiatry 11:54. 2011
    ..A particular focus was on the effects of the study design and the diagnostic procedure on the homogeneity of the sample in terms of symptom-based behavioural data, and potential consequences for further analyses based on these data...
  6. pmc The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
    Anne Farmer
    Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    BMC Psychiatry 4:42. 2004
    ..This study presents the method and socio-demographic details of the first 470 affected sibling pairs recruited from 8 different sites in Europe and the United States of America...
  7. doi request reprint What have the genomics ever done for the psychoses?
    M Gill
    Neuropsychiatric Genetics Research Group, Department of Psychiatry, School of Medicine, Trinity College Dublin 8, Ireland
    Psychol Med 40:529-40. 2010
    ..Despite the substantial heritability of the psychoses and their genuine public health burden, the applicability of the genomic approach in psychiatry has been strongly questioned or prematurely dismissed...
  8. ncbi request reprint Presenilin 1 and alpha-1-antichymotrypsin polymorphisms in Down syndrome: no effect on the presence of dementia
    J Tyrrell
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet 88:616-20. 1999
    ..We conclude that unlike the general population, neither PS-1 nor ACT polymorphisms appear to have a similar detrimental effect on dementia in DS. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:616-620, 1999...
  9. ncbi request reprint Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD
    K Sheehan
    Department of Genetics, Trinity College Dublin, Dublin, Ireland
    Mol Psychiatry 10:944-9. 2005
    ..These preliminary findings suggest that TPH2 is a susceptibility locus for ADHD. Further confirmation, preferably from different ethnic groups, is required to firmly implicate TPH2 in the pathophysiology of ADHD...
  10. ncbi request reprint Pseudoautosomal gene: possible association with bipolar males but not with schizophrenia
    Z Hawi
    Department of Psychiatry and Genetics, Trinity College, Dublin, Ireland
    Psychiatr Genet 9:129-34. 1999
    ..1, P = 0.14). This provides preliminary evidence that this locus or a closely mapped DNA variant (in linkage disequilibrium with the CAG repeat) may be involved in the genetic susceptibility to bipolar affective disorder in males...
  11. ncbi request reprint Dopa decarboxylase gene polymorphisms and attention deficit hyperactivity disorder (ADHD): no evidence for association in the Irish population
    Z Hawi
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Mol Psychiatry 6:420-4. 2001
    ..This provides preliminary evidence that this locus or a closely mapped DNA variant may be involved in the genetic susceptibility to ADHD. However, further studies are required to either confirm or refute these observations...
  12. ncbi request reprint No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample
    Z Hawi
    Department of Genetics and Psychiatry, Trinity College, Dublin, Ireland
    Am J Med Genet 96:282-4. 2000
    ..The absence of association between COMT alleles and ADHD indicated that this locus does not play a significant role or at least a role independent of other genes, in predisposing to ADHD in the Irish population...
  13. doi request reprint Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253
    G Donohoe
    Neuropsychiatric Genetics Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, St James Hospital, Dublin, Ireland
    Genes Brain Behav 12:203-9. 2013
    ....
  14. ncbi request reprint Serotonin transporter gene and autism: a haplotype analysis in an Irish autistic population
    J Conroy
    Department of Genetics, Smurfit Institute, Trinity College, Dublin, Ireland
    Mol Psychiatry 9:587-93. 2004
    ..3023, P=0.0069, odds ratio=1.8). This haplotype included the 12 repeat allele of the VNTR, which is associated with increased expression and may play a subtle role in the early development of the brain in affected probands...
  15. ncbi request reprint Confirmation and refinement of an 'at-risk' haplotype for schizophrenia suggests the EST cluster, Hs.97362, as a potential susceptibility gene at the Neuregulin-1 locus
    A P Corvin
    Neuropsychiatric Genetics Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College, Dublin 2, Ireland
    Mol Psychiatry 9:208-13. 2004
    ..0% vs 13.5%; P=0.036). Interestingly, this refined 'at-risk' haplotype is positioned close to an EST cluster of unknown function (Hs.97362) within intron 1 of NRG1...
  16. doi request reprint Preserved cognitive function is associated with suicidal ideation and single suicide attempts in schizophrenia
    C Delaney
    Department of Psychiatry and Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Schizophr Res 140:232-6. 2012
    ..To clarify this relationship, we investigated whether the relationship between suicidality and neurocognition varied according to differences in suicidal ideation and behavior...
  17. ncbi request reprint No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population
    Z Hawi
    Department Genetics, Trinity College, Dublin, Ireland
    Am J Med Genet 96:268-72. 2000
    ..Therefore, it is unlikely that the DRD4 7-repeat allele is associated with ADHD in the Irish population...
  18. ncbi request reprint Neurotrophin-3 gene polymorphisms and schizophrenia: no evidence for linkage or association
    M Gill
    Department of Psychiatry, Trinity College, Dublin, Ireland
    Psychiatr Genet 6:183-6. 1996
    ..We conclude that mutations or polymorphisms at this gene are unlikely to be involved in the genetic aetiology of schizophrenia...
  19. ncbi request reprint Linkage disequilibrium mapping at DAT1, DRD5 and DBH narrows the search for ADHD susceptibility alleles at these loci
    Z Hawi
    Department of Genetics and Psychiatry, Trinity College, Dublin, Ireland
    Mol Psychiatry 8:299-308. 2003
    ..Further genetic analysis is unlikely to refine the location of susceptibility variants and functional assessment of variants within associated regions is required...
  20. ncbi request reprint No evidence to support the association of the potassium channel gene hSKCa3 CAG repeat with schizophrenia or bipolar disorder in the Irish population
    Z Hawi
    Department of Psychiatry and Genetics, Trinity College, Dublin, Eire
    Mol Psychiatry 4:488-91. 1999
    ..We concluded that the polymorphism of the second CAG repeat of the hSKCa3 gene is not a risk factor in schizophrenia or bipolar disorder, at least in the Irish population...
  21. doi request reprint Functional analysis of intron 8 and 3' UTR variable number of tandem repeats of SLC6A3: differential activity of intron 8 variants
    M Hill
    Department of Psychiatry, Neuropsychiatric Genetics Research Group, Trinity College, Dublin, Ireland
    Pharmacogenomics J 10:442-7. 2010
    ..The lack of enhanced allele-specific activity in response to treatment regimes suggests that differential activity under basal conditions is the primary mode of action...
  22. doi request reprint Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility
    C O'Dushlaine
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Mol Psychiatry 16:286-92. 2011
    ..Similar pathways have also emerged from a pathway analysis of autism, suggesting that mechanisms involved in neuronal cell adhesion may contribute broadly to neurodevelopmental psychiatric phenotypes...
  23. doi request reprint ADHD and DAT1: further evidence of paternal over-transmission of risk alleles and haplotype
    Z Hawi
    Neuropsychiatric Genetics Research Group, Discipline of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 153:97-102. 2010
    ..Although the mechanism driving the paternal over-transmission of the DAT risk alleles is not known, these finding provide further support for this phenomenon...
  24. ncbi request reprint Sibling pairs with affective disorders: resemblance of demographic and clinical features
    E O'Mahony
    Department of Psychiatry, Trinity College Dublin and St James Hospital, Dublin, Republic of Ireland
    Psychol Med 32:55-61. 2002
    ..The aim of the study was to identify clinical characteristics that had a high degree of familiality...
  25. pmc Home environment: association with hyperactivity/impulsivity in children with ADHD and their non-ADHD siblings
    A Mulligan
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Child Care Health Dev 39:202-12. 2013
    ..We wished to ascertain if there is an association between symptoms of attention-deficit/hyperactivity disorder (ADHD) and home environment in children with ADHD and non-ADHD siblings, controlling for other environmental measures...
  26. ncbi request reprint Dementia in people with Down's syndrome
    J Tyrrell
    Department of Psychiatry, Trinity College Dublin, Dublin 2, Ireland
    Int J Geriatr Psychiatry 16:1168-74. 2001
    ..To determine the prevalence of dementia in an Irish sample of people with Down's syndrome (DS) and to examine associated clinical characteristics of dementia in this group...
  27. doi request reprint The Letter-Number Sequencing Test and its association with potential to work among people with psychotic illness
    A Murtagh
    St John of God Hospital Stillorgan, Dublin, Ireland
    Eur Psychiatry 25:101-4. 2010
    ..Letter-number sequencing may warrant further investigation as a clinically useful tool to inform decisions around vocational rehabilitation...
  28. ncbi request reprint Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample
    A Corvin
    Neuropsychiatric Genetics Group, Institute of Molecular Medicine, Trinity College Dublin, St James Hospital, James Street, Dublin 8, Ireland
    Am J Med Genet B Neuropsychiatr Genet 144:949-53. 2007
    ..3 (1.4, 60.5). Based on these data, more systematic investigation of genes involved in DAO signaling is required...
  29. doi request reprint The Social Communication Questionnaire in a sample of the general population of school-going children
    A Mulligan
    The Department of Psychiatry, Trinity Centre for Health Sciences, St James s Hospital, Dublin 8, Ireland
    Ir J Med Sci 178:193-9. 2009
    ..The social communication questionnaire (SCQ) for autistic spectrum disorder was previously validated in clinical populations...
  30. doi request reprint Effects of ZNF804A on auditory P300 response in schizophrenia
    T O'Donoghue
    1 Neuropsychiatric Genetics Group and Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, St James Hospital, Dublin, Ireland 2 Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland
    Transl Psychiatry 4:e345. 2014
    ..It is also consistent with the idea that ZNF804A may have an impact on cortical efficiency, reflected in the higher levels of activations required to achieve comparable behavioural accuracy on the task used. ..
  31. doi request reprint The cognitive genetics of neuropsychiatric disorders
    A Corvin
    Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Curr Top Behav Neurosci 12:579-613. 2012
    ..Finally, we review the analysis of whole-genome DNA sequence data and the challenges that this will bring for cognitive genomics research...
  32. ncbi request reprint Late onset Alzheimer's disease and apolipoprotein association in the Irish population: relative risk and attributable fraction
    Z Hawi
    Department of Genetics, Trinity College, Dublin, Ireland
    Ir J Med Sci 172:74-6. 2003
    ..Familial and sporadic late onset Alzheimer's disease (LOAD) shows a consistent genetic association with APOE epsilon4...
  33. ncbi request reprint Unravelling the genome: a review of molecular genetic research in schizophrenia
    J Sanders
    Department of Psychiatry, Trinity Centre for Health Sciences, St James Hospital, James Street, Dublin 8, Ireland
    Ir J Med Sci 176:5-9. 2007
    ..Despite intensive research over the years, the aetiology and pathogenesis of schizophrenia is poorly understood. However, it has long been recognised that schizophrenia is highly familial suggesting a possible genetic aetiology...
  34. ncbi request reprint A pilot study of the reliability and validity of the Caregiver Activity Survey - Intellectual Disability (CAS-ID)
    M McCarron
    Department of Psychiatry, Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland
    J Intellect Disabil Res 46:605-12. 2002
    ..An amended version of this survey, the Caregiver Activity Survey - Intellectual Disability (CAS-ID), was developed and tested for use by professional caregivers in the present study...
  35. ncbi request reprint Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multi-centre sample
    Z Hawi
    Department of Genetics and Psychiatry, Trinity College, Dublin, Ireland
    Mol Psychiatry 7:718-25. 2002
    ..9, P = 0.026). These preliminary data suggest an important role for the serotonin system in the development of ADHD. Further studies, preferentially including different ethnic groups are required to substantiate these findings...
  36. ncbi request reprint Health co-morbidities in ageing persons with Down syndrome and Alzheimer's dementia
    M McCarron
    School of Nursing and Midwifery Studies, Trinity College, Dublin, Ireland
    J Intellect Disabil Res 49:560-6. 2005
    ..AIM To investigate and measure health co-morbidities in ageing persons with Down syndrome with and without AD...
  37. ncbi request reprint Cigarette smoking and psychotic symptoms in bipolar affective disorder
    A Corvin
    Department of Psychiatry, Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland
    Br J Psychiatry 179:35-8. 2001
    ..An association exists between smoking and schizophrenia, independent of other factors and related to psychotic symptomatology...