Research Topics
Genomes and GenesSpecies | Louise GallagherSummaryAffiliation: Trinity College Country: Ireland Publications
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Detail Information
Publications
Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attentionKatherine A Johnson
School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
Neuropsychologia 45:2234-45. 2007..These data imply involvement of fronto-parietal attentional networks and sub-cortical arousal systems in the pathology of ADHD and prefrontal cortex dysfunction in children with HFA...
Brief report: A case of autism associated with del(2)(q32.1q32.2) or (q32.2q32.3)Louise Gallagher
Department of Psychiatry, Trinity College, Dublin, Republic of Ireland
J Autism Dev Disord 33:105-8. 2003..The deletion seems to correspond with regions emerging from linkage studies. We propose this as a possible candidate region in the search for autism genes...
No association between allelic variants of HOXA1/HOXB1 and autismLouise Gallagher
Department of Genetics, Smurfit Institute for Genetics, Trinity College, Dublin 2, Ireland
Am J Med Genet B Neuropsychiatr Genet 124:64-7. 2004..We also report negative findings for HOXB1 variants. We conclude that the HOXA1/B1 are unlikely to be the susceptibility genes for autism in our sample...
Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorderZiarih Hawi
Department of Psychiatry and Genetics, Trinity College, Dublin, Ireland
Am J Hum Genet 77:958-65. 2005..Possible reasons for this preferential transmission include imprinting and ascertainment bias, although results of further analyses show that the latter is unlikely...
Fine mapping and association studies in a candidate region for autism on chromosome 2q31-q32Judith Conroy
Neuropsychiatric Genetics Research Group, Trinity Centre for Health Sciences, Trinity College Dublin, Dublin, Ireland
Am J Med Genet B Neuropsychiatr Genet 150:535-44. 2009..The combined sample showed evidence of association with rs12690517 (OR = 1.3; P = 0.008) and surrounding haplotypes. The findings indicate some evidence for the role of ITGA4 as candidate gene for autism...
Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sampleLynne E Cochrane
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College, Dublin, Ireland
Autism Res 3:342-4. 2010..01 < P < 0.05) and to have unremarkable findings. Our data indicates that in the Irish autism sample the integrin genes tested here do not play an important role in the aetiology of autism...
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorderJillian P Casey
School of Medicine and Medical Science University College, Dublin, Ireland
Hum Genet 131:565-79. 2012..10). Our findings highlight the applicability of HH mapping in complex disorders such as ASD and offer an alternative approach to the analysis of genome-wide association data...
Protein kinase C-beta 1 gene variants are not associated with autism in the Irish populationMao S Yang
Department of Psychiatry, Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland, and Laboratory of Disorder Genes, Chongqing University of Medical Sciences, Chongqing, PR China
Psychiatr Genet 17:39-41. 2007..Our data do not support the finding that the PRKCB1 gene variants contribute risk for the development of autism...
Confirmation of association between autism and the mitochondrial aspartate/glutamate carrier SLC25A12 gene on chromosome 2q31Ricardo Segurado
Department of Genetics, Trinity College, Dublin 2, Ireland
Am J Psychiatry 162:2182-4. 2005..4 and 4.8. The authors' goal was to investigate this association with autism in Irish affected child-parent trios because replication in an independent sample is essential in the validation of such potentially important findings...
A genome-wide scan for common alleles affecting risk for autismRichard Anney
Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland
Hum Mol Genet 19:4072-82. 2010..Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C...
Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: genetic and molecular studiesKatherine E Tansey
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin 8, Ireland
Neurosci Lett 474:163-7. 2010..Data presented here does not support the role of common genetic variation in OXTR in the aetiology of autism spectrum disorders in Caucasian samples...
Individual common variants exert weak effects on the risk for autism spectrum disorderspiRichard Anney
Autism Genetics Group, Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland
Hum Mol Genet 21:4781-92. 2012..Based on results from individual SNPs and their en masse effect on risk, as inferred from the allele score results, it is reasonable to conclude that common variants affect the risk for ASD but their individual effects are modest...
Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disordersRichard J L Anney
Autism Genetics Group, Department of Psychiatry, Trinity College Dublin, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland
Eur J Hum Genet 19:1082-9. 2011..Both genes and processes that show enrichment have previously been examined in autistic disorders and offer biologically plausibility to these findings...
Detecting subtle facial emotion recognition deficits in high-functioning Autism using dynamic stimuli of varying intensitiesMiriam J Law Smith
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
Neuropsychologia 48:2777-81. 2010....
Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for autismKatherine E Tansey
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
Mol Autism 2:3. 2011..abstract:..
Exploration of empirical Bayes hierarchical modeling for the analysis of genome-wide association study dataElizabeth A Heron
Neuropsychiatric Genetics Research Group and Department of Psychiatry, Trinity College Dublin, Trinity Centre for Health Sciences, James s Street, Dublin 8, Ireland
Biostatistics 12:445-61. 2011..Our results agree with previous findings and in the case of one data set (Crohn's disease) suggest an additional region of interest...
Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sampleLynne E Cochrane
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College, Dublin, Ireland
Autism Res 3:342-4. 2010..01<P<0.05) and to have unremarkable findings. Our data indicates that in the Irish autism sample the integrin genes tested here do not play an important role in the aetiology of autism...
Atypical visuospatial processing in autism: insights from functional connectivity analysisJane McGrath
Department of Psychiatry, Trinity Centre for Health Sciences, St James s Hospital, Dublin, Ireland
Autism Res 5:314-30. 2012..Overall, this study has identified a relative advantage in mental rotation in ASD that is associated with aberrant neural connectivity and that may stem from enhanced visual perceptual processing...
Social and monetary reward processing in autism spectrum disordersSonja Delmonte
Department of Psychiatry, Trinity College Dublin, Dublin, 2, Ireland
Mol Autism 3:7. 2012..abstract:..
Copy-number variants in neurodevelopmental disorders: promises and challengesAlison K Merikangas
Department of Psychiatry, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland
Trends Genet 25:536-44. 2009....
Psychosis, affective disorders and anxiety in autistic spectrum disorder: prevalence and nosological considerationsNorbert Skokauskas
Department of Child Psychiatry, St James s Hospital, Dublin, Ireland
Psychopathology 43:8-16. 2010....
Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypesHeather C Mefford
University of Washington School of Medicine, Seattle 98195, USA
N Engl J Med 359:1685-99. 2008..Advances in technologies to detect these changes allow for the routine identification of submicroscopic imbalances in large numbers of patients...
Midwifery-led care in Ireland: an educationDeirdre Daly
University of Dublin Trinity College
Pract Midwife 9:26-8. 2006
