Michael Ewers

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. pmc Blood-based biomarkers of microvascular pathology in Alzheimer's disease
    Michael Ewers
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College, University of Dublin, The Adelaide and Meath Hospital incorporating the National Children s Hospital, Tallaght, Dublin, Ireland
    Exp Gerontol 45:75-9. 2010
  2. doi request reprint Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment
    Arun L W Bokde
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Alzheimer Memorial Center, Munich, Germany
    J Alzheimers Dis 21:103-18. 2010
  3. pmc Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease
    Claudia Plant
    Department of Neuroradiology, Technische Universitat Munchen, Munich, Germany
    Neuroimage 50:162-74. 2010
  4. doi request reprint Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease
    Michael Ewers
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College, University of Dublin, The Adelaide and Meath Hospital incorporating the National Children s Hospital, Tallaght, Ireland
    J Alzheimers Dis 25:373-81. 2011
  5. doi request reprint Alzheimer disease: functional abnormalities in the dorsal visual pathway
    Arun L W Bokde
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College Dublin, Adelaide and Meath Hospital incorporating National Children s Hospital, Dublin, Ireland
    Radiology 254:219-26. 2010
  6. doi request reprint Assessing neuronal networks: understanding Alzheimer's disease
    Arun L W Bokde
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience TCIN, Laboratory of Neuroimaging and Biomarker Research, Trinity College Dublin, The Adelaide and Meath Hospital Incorporating The National Children s Hospital AMiNCH, Dublin 24, Ireland
    Prog Neurobiol 89:125-33. 2009
  7. ncbi request reprint Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study
    Harald Hampel
    Trinity Center for Health Sciences, The Adelaide and Meath Hospital Incorporating The National Children s Hospital AMiNCH, Tallaght, Dublin 24, Ireland
    J Clin Psychiatry 70:922-31. 2009
  8. doi request reprint Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease
    Michael Ewers
    Department of Psychiatry, Alzheimer Memorial Center, Ludwig Maximilian University, Munich, Germany
    Brain 131:1252-8. 2008
  9. ncbi request reprint Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment
    Stefan J Teipel
    Alzheimer Memorial Center, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336, Munich, Germany
    Neuroimage 38:13-24. 2007
  10. doi request reprint Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
    Katharina Buerger
    Department of Psychiatry, Ludwig Maximilian University Munich, Munich, Germany
    Exp Gerontol 44:579-85. 2009

Detail Information

Publications11

  1. pmc Blood-based biomarkers of microvascular pathology in Alzheimer's disease
    Michael Ewers
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College, University of Dublin, The Adelaide and Meath Hospital incorporating the National Children s Hospital, Tallaght, Dublin, Ireland
    Exp Gerontol 45:75-9. 2010
    ....
  2. doi request reprint Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment
    Arun L W Bokde
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University, Alzheimer Memorial Center, Munich, Germany
    J Alzheimers Dis 21:103-18. 2010
    ..The activation differences between groups may be compensatory mechanisms within the MCI group for the effects of the putative AD neuropathology. This has been the first study that has examined verbal working memory in MCI...
  3. pmc Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease
    Claudia Plant
    Department of Neuroradiology, Technische Universitat Munchen, Munich, Germany
    Neuroimage 50:162-74. 2010
    ..The present results suggest that novel multivariate methods of pattern matching reach a clinically relevant accuracy for the a priori prediction of the progression from MCI to AD...
  4. doi request reprint Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease
    Michael Ewers
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College, University of Dublin, The Adelaide and Meath Hospital incorporating the National Children s Hospital, Tallaght, Ireland
    J Alzheimers Dis 25:373-81. 2011
    ..Thus, the CSF biomarker candidate of BACE1 activity was associated with hippocampus atrophy in AD in a robust manner and may reflect neurotoxic amyloid-β-related processes...
  5. doi request reprint Alzheimer disease: functional abnormalities in the dorsal visual pathway
    Arun L W Bokde
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Laboratory of Neuroimaging and Biomarker Research, Trinity College Dublin, Adelaide and Meath Hospital incorporating National Children s Hospital, Dublin, Ireland
    Radiology 254:219-26. 2010
    ..To evaluate whether patients with Alzheimer disease (AD) have altered activation compared with age-matched healthy control (HC) subjects during a task that typically recruits the dorsal visual pathway...
  6. doi request reprint Assessing neuronal networks: understanding Alzheimer's disease
    Arun L W Bokde
    Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience TCIN, Laboratory of Neuroimaging and Biomarker Research, Trinity College Dublin, The Adelaide and Meath Hospital Incorporating The National Children s Hospital AMiNCH, Dublin 24, Ireland
    Prog Neurobiol 89:125-33. 2009
    ....
  7. ncbi request reprint Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study
    Harald Hampel
    Trinity Center for Health Sciences, The Adelaide and Meath Hospital Incorporating The National Children s Hospital AMiNCH, Tallaght, Dublin 24, Ireland
    J Clin Psychiatry 70:922-31. 2009
    ..In the current study, we tested the effect of short-term lithium treatment in patients with Alzheimer's disease...
  8. doi request reprint Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease
    Michael Ewers
    Department of Psychiatry, Alzheimer Memorial Center, Ludwig Maximilian University, Munich, Germany
    Brain 131:1252-8. 2008
    ..The assessment of BACE 1 in CSF may provide a sensitive measure to detect in vivo alterations in the amyloidogenic processing potentially modified by the ApoE genotype...
  9. ncbi request reprint Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment
    Stefan J Teipel
    Alzheimer Memorial Center, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, 80336, Munich, Germany
    Neuroimage 38:13-24. 2007
    ..Our findings indicate that multivariate network analysis of deformation maps detects typical features of AD pathology and provides a powerful tool to predict conversion into AD in non-demented at risk patients...
  10. doi request reprint Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI)
    Katharina Buerger
    Department of Psychiatry, Ludwig Maximilian University Munich, Munich, Germany
    Exp Gerontol 44:579-85. 2009
    ..Data of the pilot European-ADNI (E-ADNI) biological marker programme of cerebrospinal fluid (CSF) and plasma candidate biomarkers are reported...
  11. ncbi request reprint Long-term cost-effectiveness of donepezil for the treatment of Alzheimer's disease
    Stefan J Teipel
    Alzheimer Memorial Center and Geriatric Psychiatry Branch, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig Maximilian University, Nussbaumstr 7, Munich, 80336, Germany
    Eur Arch Psychiatry Clin Neurosci 257:330-6. 2007
    ..However, use of ChE inhibitors is limited by budget constraints and disincentives on the side of health insurances and nursing care insurances...