Genomes and Genes
Jennifer K Dowling
Affiliation: Trinity College
- Biochemical regulation of the inflammasomeJennifer K Dowling
Inflammation Research Group, School of Biochemistry and Immunology, Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
Crit Rev Biochem Mol Biol 47:424-43. 2012..Here, we review current knowledge surrounding the biochemical regulation of the NLRP1, NLRP3, NLRC4, AIM2 and IFI16 inflammasomes...
- Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activationJennifer K Dowling
From the Trinity Biomedical Sciences Institute, School of Biochemistry and Immunology, Trinity College Dublin, Pearse Street, Dublin 2, Ireland
J Biol Chem 289:6429-37. 2014..Collectively, our data indicate that PML limits ASC function, retaining ASC in the nucleus. ..