Mark A Bellgrove

Summary

Affiliation: Trinity College
Country: Ireland

Publications

  1. ncbi Local-global processing in early-onset schizophrenia: evidence for an impairment in shifting the spatial scale of attention
    Mark A Bellgrove
    Department of Psychology, Monash University, Clayton, Vic, Australia
    Brain Cogn 51:48-65. 2003
  2. ncbi Attenuation of spatial attentional asymmetries with poor sustained attention
    Mark A Bellgrove
    Department of Psychology and the Institute of Neuroscience, Trinity College Dublin, Ireland
    Neuroreport 15:1065-9. 2004
  3. ncbi The functional neuroanatomical correlates of response variability: evidence from a response inhibition task
    Mark A Bellgrove
    Department of Psychology, Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 42:1910-6. 2004
  4. ncbi Attenuation of perceptual asymmetries in patients with early-onset schizophrenia: evidence in favour of reduced hemispheric differentiation in schizophrenia?
    Mark A Bellgrove
    Monash University, Victoria, Australia
    Laterality 9:79-91. 2004
  5. ncbi The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Exp Brain Res 163:352-60. 2005
  6. ncbi DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): effects of associated alleles at the VNTR and -521 SNP
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 136:81-6. 2005
  7. ncbi Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype
    Mark A Bellgrove
    Department of Psychology, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Neuropsychologia 43:1847-57. 2005
  8. ncbi The neural correlates of deficient error awareness in attention-deficit hyperactivity disorder (ADHD)
    Redmond G O'Connell
    Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 47:1149-59. 2009
  9. ncbi fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD
    Wouter Braet
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 49:1641-50. 2011
  10. ncbi Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls
    Katherine A Johnson
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 147:927-37. 2008

Detail Information

Publications43

  1. ncbi Local-global processing in early-onset schizophrenia: evidence for an impairment in shifting the spatial scale of attention
    Mark A Bellgrove
    Department of Psychology, Monash University, Clayton, Vic, Australia
    Brain Cogn 51:48-65. 2003
    ..These findings suggest an impaired ability to shift the spatial scale of attention from a global to a local spatial scale in early-onset schizophrenia...
  2. ncbi Attenuation of spatial attentional asymmetries with poor sustained attention
    Mark A Bellgrove
    Department of Psychology and the Institute of Neuroscience, Trinity College Dublin, Ireland
    Neuroreport 15:1065-9. 2004
    ..Our results provide further support for the notion that sustained attention may exert a modulatory influence on spatial attention...
  3. ncbi The functional neuroanatomical correlates of response variability: evidence from a response inhibition task
    Mark A Bellgrove
    Department of Psychology, Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 42:1910-6. 2004
    ....
  4. ncbi Attenuation of perceptual asymmetries in patients with early-onset schizophrenia: evidence in favour of reduced hemispheric differentiation in schizophrenia?
    Mark A Bellgrove
    Monash University, Victoria, Australia
    Laterality 9:79-91. 2004
    ....
  5. ncbi The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Exp Brain Res 163:352-60. 2005
    ..Against this background, the slower clearance of dopamine associated with the methionine variant of the COMT gene polymorphism may be disadvantageous to cognition in ADHD...
  6. ncbi DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): effects of associated alleles at the VNTR and -521 SNP
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 136:81-6. 2005
    ....
  7. ncbi Dissecting the attention deficit hyperactivity disorder (ADHD) phenotype: sustained attention, response variability and spatial attentional asymmetries in relation to dopamine transporter (DAT1) genotype
    Mark A Bellgrove
    Department of Psychology, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Neuropsychologia 43:1847-57. 2005
    ..Our results suggest that the 10-repeat DAT1 allele may mediate neuropsychological impairment in ADHD. The application of molecular genetics may help to define neuropsychological impaired subgroups of ADHD...
  8. ncbi The neural correlates of deficient error awareness in attention-deficit hyperactivity disorder (ADHD)
    Redmond G O'Connell
    Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 47:1149-59. 2009
    ..Our data provide evidence that neuropsychological deficits associated with ADHD can be exacerbated by error processing abnormalities. Error awareness may represent an important cognitive and physiological phenotype for ADHD...
  9. ncbi fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD
    Wouter Braet
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 49:1641-50. 2011
    ..Finally, the ADHD group displayed decreased activation in parietal and (pre)frontal regions during response inhibition, and in frontal and medial brain regions on error trials...
  10. ncbi Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls
    Katherine A Johnson
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Am J Med Genet B Neuropsychiatr Genet 147:927-37. 2008
    ..Absence of the 7-repeat allele in children with ADHD is associated with a neurocognitive profile of drifting sustained attention that gives rise to variable and inconsistent performance...
  11. ncbi Impaired conflict resolution and alerting in children with ADHD: evidence from the Attention Network Task (ANT)
    Katherine A Johnson
    School of Psychology and Trinity College Institute of Neuroscience, University of Dublin, Trinity College Dublin, Ireland
    J Child Psychol Psychiatry 49:1339-47. 2008
    ..This theory holds promise for dissociating discrete patterns of cognitive impairment in disorders where attentional deficits may often be subtle, such as in attention deficit hyperactivity disorder (ADHD)...
  12. ncbi Dissociation in response to methylphenidate on response variability in a group of medication naïve children with ADHD
    Katherine A Johnson
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 46:1532-41. 2008
    ..MPH administration may have a specific effect on those performance components that reflect sustained attention and top-down control rather than arousal...
  13. ncbi Neurochemical enhancement of conscious error awareness
    Robert Hester
    Department of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia
    J Neurosci 32:2619-27. 2012
    ....
  14. ncbi Two types of action error: electrophysiological evidence for separable inhibitory and sustained attention neural mechanisms producing error on go/no-go tasks
    Redmond G O'Connell
    Trinity College Dublin, Dublin, Ireland
    J Cogn Neurosci 21:93-104. 2009
    ..Our data provide an electrophysiological dissociation of sustained attention and response inhibition...
  15. ncbi Uncovering the neural signature of lapsing attention: electrophysiological signals predict errors up to 20 s before they occur
    Redmond G O'Connell
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    J Neurosci 29:8604-11. 2009
    ..Our results show that the specific neural signatures of attentional lapses are registered in the EEG up to 20 s before an error...
  16. ncbi Dissociation in performance of children with ADHD and high-functioning autism on a task of sustained attention
    Katherine A Johnson
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 45:2234-45. 2007
    ..These data imply involvement of fronto-parietal attentional networks and sub-cortical arousal systems in the pathology of ADHD and prefrontal cortex dysfunction in children with HFA...
  17. ncbi Dopaminergic genotype influences spatial bias in healthy adults
    Ciara M Greene
    Trinity College Institute of Neuroscience, Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland
    Neuropsychologia 48:2458-64. 2010
    ..These results provide the first evidence of genetic modulation of spatial bias in healthy adults...
  18. ncbi Noradrenergic genotype predicts lapses in sustained attention
    Ciara M Greene
    Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland
    Neuropsychologia 47:591-4. 2009
    ..The decrease in noradrenaline occasioned by the T allele may impair sustained attention by reducing participants' ability to remain alert throughout the task and by increasing their susceptibility to distractors...
  19. ncbi Dopamine transporter genotype predicts attentional asymmetry in healthy adults
    Daniel P Newman
    Monash University, School of Psychology and Psychiatry, Victoria, Australia
    Neuropsychologia 50:2823-9. 2012
    ..These data add to a growing body of evidence showing that spatial attentional asymmetry is a stable quantitative trait, with individual differences in this trait significantly predicted by common DNA variation in the DAT1 gene...
  20. ncbi Self-Alert Training: volitional modulation of autonomic arousal improves sustained attention
    Redmond G O'Connell
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 46:1379-90. 2008
    ..These findings have important implications for the rehabilitation of attention deficits arising from frontal dysfunction...
  21. ncbi The role of cingulate cortex in the detection of errors with and without awareness: a high-density electrical mapping study
    Redmond G O'Connell
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Eur J Neurosci 25:2571-9. 2007
    ..These findings may be particularly important in the context of clinical studies in which a proper understanding of self-monitoring deficits requires an explicit measurement of error awareness...
  22. ncbi Stop task after-effects in schizophrenia: behavioral control adjustments and repetition priming
    Peter G Enticott
    School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia
    Neurocase 18:405-14. 2012
    ....
  23. ncbi Functional developmental changes underlying response inhibition and error-detection processes
    Wouter Braet
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 47:3143-51. 2009
    ..Instead, the neurodevelopmental trajectory of these important executive functions may reveal the basis for the immature executive functioning of the young adolescent...
  24. ncbi Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder
    Mark A Bellgrove
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Neuropsychopharmacology 30:2290-7. 2005
    ..Our results suggest a subgroup of children with ADHD for whom the 10-repeat DAT1 allele is associated with left-sided inattention. MPH may be most efficacious in this group because it ameliorates a DAT1-mediated hypodopaminergic state...
  25. ncbi Response variability in attention deficit hyperactivity disorder: evidence for neuropsychological heterogeneity
    Katherine A Johnson
    Schools of Psychiatry and Genetics and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland
    Neuropsychologia 45:630-8. 2007
    ..The consistently poor performance in fast-frequency variability and error rates may be due to difficulties in sustained attention that fluctuate on a trial-to-trial basis...
  26. ncbi The cognitive genetics of attention deficit hyperactivity disorder (ADHD): sustained attention as a candidate phenotype
    Mark A Bellgrove
    Department of Psychology, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Cortex 42:838-45. 2006
    ..The DBH gene may contribute to the susceptibility for ADHD, in part because of its varying effects on the development of brain mechanisms mediating sustained attention...
  27. ncbi Cognitive remediation in ADHD: effects of periodic non-contingent alerts on sustained attention to response
    Redmond G O'Connell
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Neuropsychol Rehabil 16:653-65. 2006
    ..Methods from the field of cognitive rehabilitation may be viably applied to the remediation of attention deficits in ADHD...
  28. ncbi Reduced electrodermal response to errors predicts poor sustained attention performance in attention deficit hyperactivity disorder
    Redmond G O'Connell
    Department of Psychology and Trinity College Institute of Neuroscience, Dublin 2, Ireland
    Neuroreport 15:2535-8. 2004
    ....
  29. ncbi Stop task after-effects: the extent of slowing during the preparation and execution of movement
    Peter G Enticott
    School of Psychology, Psychiatry and Psychological Medicine, Monash University, Australia
    Exp Psychol 56:247-51. 2009
    ....
  30. ncbi Sustained attention in traumatic brain injury (TBI) and healthy controls: enhanced sensitivity with dual-task load
    Paul M Dockree
    Department of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, 2, Ireland
    Exp Brain Res 168:218-29. 2006
    ..We conclude that the dual-task demand associated with this task enhances its sensitivity as a measure of sustained attention in TBI patients and neurologically healthy controls that relates to everyday slips of attention...
  31. ncbi Imaging the genetics of executive function
    Ciara M Greene
    Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland
    Biol Psychol 79:30-42. 2008
    ..While the findings in the populations studied do not always converge, they all point to the usefulness of neuroimaging techniques such as fMRI as potential endophenotypes for parsing the genetic aetiology of executive function...
  32. ncbi Lateralized deficit of response inhibition in early-onset schizophrenia
    Mark A Bellgrove
    Cognitive Neuroscience Laboratory, School of Behavioural Science, University of Melbourne, Parkville, Victoria, Australia
    Psychol Med 36:495-505. 2006
    ..Relatively few studies have examined response inhibition in schizophrenia, and none in adolescent patients with early-onset schizophrenia (EOS)...
  33. ncbi Epistasis between neurochemical gene polymorphisms and risk for ADHD
    Ricardo Segurado
    Neuropsychiatric Genetics Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
    Eur J Hum Genet 19:577-82. 2011
    ..Furthermore, the size of these effects is of interest and attempts to replicate these results in other samples are anticipated...
  34. ncbi Variability in time reproduction: difference in ADHD combined and inattentive subtypes
    Celine Mullins
    Department of Psychology, Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland
    J Am Acad Child Adolesc Psychiatry 44:169-76. 2005
    ....
  35. ncbi Influence of attentional load on spatial attention in acquired and developmental disorders of attention
    Mark A Bellgrove
    Monash University, School of Psychology and Psychiatry, Clayton, Australia The University of Queensland, School of Psychology and Queensland Brain Institute QBI, Brisbane, Australia Electronic address
    Neuropsychologia 51:1085-93. 2013
    ..Our findings support the view that spatial attention networks are tightly integrated with non-lateralized aspects of attention...
  36. ncbi DNA Variation in the SNAP25 Gene Confers Risk to ADHD and Is Associated with Reduced Expression in Prefrontal Cortex
    Ziarih Hawi
    Queensland Brain Institute, The University of Queensland, Brisbane, Australia School of Psychology and Psychiatry, Monash University, Melbourne, Australia
    PLoS ONE 8:e60274. 2013
    ..CONCLUSIONS: Our data show that DNA variation at SNAP25 confers risk to ADHD and reduces the expression of the transcript in a region of the brain that is critical for the regulation of attention and inhibition...
  37. ncbi An examination of movement kinematics in young people with high-functioning autism and Asperger's disorder: further evidence for a motor planning deficit
    Nicole J Rinehart
    Centre for Developmental Psychiatry and Psychology, Department of Psychological Medicine, Monash University, Monash Medical Centre, 246, Clayton Road, Clayton, Victoria, Australia
    J Autism Dev Disord 36:757-67. 2006
    ..g. "motor clumsiness" in AD versus "abnormal posturing" in autism. It will be important for future research to map the developmental trajectory of motor abnormalities in these disorder groups...
  38. ncbi Executive "brake failure" following deactivation of human frontal lobe
    Christopher D Chambers
    University of Melbourne, Melbourne, Australia
    J Cogn Neurosci 18:444-55. 2006
    ..These findings confirm and extend recent reports that the inferior frontal gyrus is vital for mediating response inhibition...
  39. ncbi Dissociable mechanisms of cognitive control in prefrontal and premotor cortex
    Christopher D Chambers
    Institute of Cognitive Neuroscience, University College London, London, UK
    J Neurophysiol 98:3638-47. 2007
    ..The observed double dissociation of neurodisruptive effects between the right IFG and right dPM further implies that response inhibition and execution rely on distinct neural processes despite activating a common cortical network...
  40. ncbi Impaired temporal resolution of visual attention and dopamine beta hydroxylase genotype in attention-deficit/hyperactivity disorder
    Mark A Bellgrove
    Cognitive Neuroscience Laboratory, School of Behavioural Science, University of Melbourne, Victoria 3010, Australia
    Biol Psychiatry 60:1039-45. 2006
    ..Since catecholamines regulate visual attention, we examined whether participants with ADHD were impaired on a task requiring temporal attention and how DBH genotype influenced temporal attention in ADHD...
  41. ncbi A neurobehavioral examination of individuals with high-functioning autism and Asperger's disorder using a fronto-striatal model of dysfunction
    Nicole J Rinehart
    Monash University
    Behav Cogn Neurosci Rev 1:164-77. 2002
    ....
  42. ncbi Genetics of cognitive deficits in ADHD: clues for novel treatment methods
    Mark A Bellgrove
    Cognitive Neuroscience Laboratory, School of Psychology and the Queensland Brain Institute, University of Queensland, Brisbane, 4072 Queensland, Australia
    Expert Rev Neurother 8:553-61. 2008
    ....
  43. ncbi Molecular genetics of attention
    Mark A Bellgrove
    School of Psychology, University of Queensland, 4072 Queensland, Australia
    Ann N Y Acad Sci 1129:200-12. 2008
    ....