Research Topics
Genomes and GenesSpecies | Richard J L AnneySummaryAffiliation: Trinity College Country: Ireland Publications
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Detail Information
Publications
Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for autismKatherine E Tansey
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland
Mol Autism 2:3. 2011..abstract:..
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysisRobert D Oades
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
Behav Brain Funct 4:48. 2008..abstract:..
Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disordersRichard J L Anney
Autism Genetics Group, Department of Psychiatry, Trinity College Dublin, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland
Eur J Hum Genet 19:1082-9. 2011..Both genes and processes that show enrichment have previously been examined in autistic disorders and offer biologically plausibility to these findings...
Variation in the gene coding for the M5 muscarinic receptor (CHRM5) influences cigarette dose but is not associated with dependence to drugs of addiction: evidence from a prospective population based cohort study of young adultsRichard J L Anney
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
BMC Genet 8:46. 2007..We investigated whether these polymorphisms influence substance dependence and dose in a cohort of 1947 young Australians...
Parent of origin effects in attention/deficit hyperactivity disorder (ADHD): analysis of data from the international multicenter ADHD genetics (IMAGE) programRichard J L Anney
Department of Psychiatry, Trinity College Dublin, St James s Hospital, Dublin, Ireland
Am J Med Genet B Neuropsychiatr Genet 147:1495-500. 2008..We cannot however, exclude gene-specific parent of origin effect in the etiology ADHD...
Non-random error in genotype calling procedures: implications for family-based and case-control genome-wide association studiesRichard J L Anney
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
Am J Med Genet B Neuropsychiatr Genet 147:1379-86. 2008..The family-based association simulations show close to nominal type-I error at 4% genotype missingness. These findings have important implications to study design, quality-control procedures and reporting of findings in GWAS...
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics studyRichard J L Anney
Department of Neuropsychiatric Genetics, Trinity College Dublin, Ireland
Am J Med Genet B Neuropsychiatr Genet 147:1369-78. 2008..We aimed to achieve insight into the genetic etiology of a trait using a hypothesis-free study design and were able to identify a number of biologically interesting markers and genes for follow-up studies...
Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sampleLynne E Cochrane
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College, Dublin, Ireland
Autism Res 3:342-4. 2010..01 < P < 0.05) and to have unremarkable findings. Our data indicates that in the Irish autism sample the integrin genes tested here do not play an important role in the aetiology of autism...
Autism symptoms in Attention-Deficit/Hyperactivity Disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disordersAisling Mulligan
Trinity College, Dublin, Ireland
J Autism Dev Disord 39:197-209. 2009..Thus autism symptoms in ADHD represent a familial trait associated with increased neurodevelopmental and oppositional/conduct disorders...
Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulationMatthew James Hill
Neuropsychiatric Genetics Research Group, Trinity College Dublin, Institute of Molecular Medicine, Ireland
Psychiatr Genet 21:281-6. 2011..To identify cis-acting regulatory variants influencing the expression of the schizophrenia susceptibility gene chitinase 3-like 1 gene (CHI3L1) in human lymphoblasts and post-mortem brain tissue...
Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: genetic and molecular studiesKatherine E Tansey
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin 8, Ireland
Neurosci Lett 474:163-7. 2010..Data presented here does not support the role of common genetic variation in OXTR in the aetiology of autism spectrum disorders in Caucasian samples...
Fine mapping and association studies in a candidate region for autism on chromosome 2q31-q32Judith Conroy
Neuropsychiatric Genetics Research Group, Trinity Centre for Health Sciences, Trinity College Dublin, Dublin, Ireland
Am J Med Genet B Neuropsychiatr Genet 150:535-44. 2009..The combined sample showed evidence of association with rs12690517 (OR = 1.3; P = 0.008) and surrounding haplotypes. The findings indicate some evidence for the role of ITGA4 as candidate gene for autism...
Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sampleLynne E Cochrane
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College, Dublin, Ireland
Autism Res 3:342-4. 2010..01<P<0.05) and to have unremarkable findings. Our data indicates that in the Irish autism sample the integrin genes tested here do not play an important role in the aetiology of autism...
Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphismRichard J L Anney
Behavioural Genetics Laboratory, Murdoch Childrens Research Institute, Royal Children s Hospital, University of Melbourne, Parkville, Melbourne, Australia
Pharmacogenetics 14:73-81. 2004..Including these data, three independent studies, two of which use identical phenotypes, have now identified a protective relationship between the K4 allele of the functional HUMTH01-VNTR polymorphism and high-level smoking...
Association between the COMT Val158Met polymorphism and propensity to anxiety in an Australian population-based longitudinal study of adolescent healthCraig A Olsson
Centre for Adolescent Health, Murdoch Children s Research Institute, Royal Children s Hospital, University of Melbourne, Victoria, Australia
Psychiatr Genet 15:109-15. 2005..Two recent reports have observed the association between the MetMet genotype and risk of anxiety in adult populations. We examined the association between the ValMet genotypes and propensity to anxiety across adolescence...
