P McMonagle

Summary

Affiliation: St Vincent's University Hospital
Country: Ireland

Publications

  1. ncbi request reprint Phenotype of AD-HSP due to mutations in the SPAST gene: comparison with AD-HSP without mutations
    P McMonagle
    Department of Neurology, St Vincent s University Hospital and Department of Pathology, University College Dublin and St Vincent s University Hospital, Dublin, Ireland
    Neurology 55:1794-800. 2000
  2. doi request reprint Dementia in SPG4 hereditary spastic paraplegia: clinical, genetic, and neuropathologic evidence
    S Murphy
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Neurology 73:378-84. 2009
  3. ncbi request reprint SPG15, a new locus for autosomal recessive complicated HSP on chromosome 14q
    C A Hughes
    Department of Pathology, University College Dublin and St Vincent s University Hospital, Dublin, Ireland
    Neurology 56:1230-3. 2001
  4. pmc The prevalence of "pure" autosomal dominant hereditary spastic paraparesis in the island of Ireland
    P McMonagle
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    J Neurol Neurosurg Psychiatry 72:43-6. 2002
  5. ncbi request reprint Hereditary spastic paraparesis and psychosis
    P McMonagle
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin, Ireland
    Eur J Neurol 13:874-9. 2006
  6. ncbi request reprint Presenilin-1 mutation (E280G), spastic paraparesis, and cranial MRI white-matter abnormalities
    S O'Riordan
    St Vincent s University Hospital, Dublin, Ireland
    Neurology 59:1108-10. 2002

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Phenotype of AD-HSP due to mutations in the SPAST gene: comparison with AD-HSP without mutations
    P McMonagle
    Department of Neurology, St Vincent s University Hospital and Department of Pathology, University College Dublin and St Vincent s University Hospital, Dublin, Ireland
    Neurology 55:1794-800. 2000
    ..There are at least seven genetic loci with varying ages at onset and disability. The SPAST gene at the SPG4 locus on chromosome 2p is the major disease gene for AD-HSP...
  2. doi request reprint Dementia in SPG4 hereditary spastic paraplegia: clinical, genetic, and neuropathologic evidence
    S Murphy
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Neurology 73:378-84. 2009
    ..There has only been one postmortem examination described; not all accept that progressive cognitive decline is a feature of this disorder...
  3. ncbi request reprint SPG15, a new locus for autosomal recessive complicated HSP on chromosome 14q
    C A Hughes
    Department of Pathology, University College Dublin and St Vincent s University Hospital, Dublin, Ireland
    Neurology 56:1230-3. 2001
    ..20 at zero recombination). Haplotype construction of nearby markers confirms the existence of this novel HSP locus (SPG15) and narrows it to a 19-cM interval flanked by D14S1038 and D14S61...
  4. pmc The prevalence of "pure" autosomal dominant hereditary spastic paraparesis in the island of Ireland
    P McMonagle
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    J Neurol Neurosurg Psychiatry 72:43-6. 2002
    ..Previous studies have included autosomal recessive and sporadic cases in prevalence calculations. This study aimed to determine the prevalence and features of pure ADHSP in the island of Ireland...
  5. ncbi request reprint Hereditary spastic paraparesis and psychosis
    P McMonagle
    Department of Neurology, St Vincent s University Hospital, Elm Park, Dublin, Ireland
    Eur J Neurol 13:874-9. 2006
    ..We found a higher than expected rate of psychosis in the Irish HSP population. Two groups of HSP patients may have increased risk of developing psychosis: those with Kjellin's syndrome and those with SPG4-HSP...
  6. ncbi request reprint Presenilin-1 mutation (E280G), spastic paraparesis, and cranial MRI white-matter abnormalities
    S O'Riordan
    St Vincent s University Hospital, Dublin, Ireland
    Neurology 59:1108-10. 2002
    ..Another affected sibling also had MRI white matter abnormalities. The MRI findings may reflect an ischemic leukoencephalopathy due to amyloid angiopathy affecting meningocortical vessels...