Kathy Gately

Summary

Affiliation: St James's Hospital
Country: Ireland

Publications

  1. doi request reprint High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer
    Kathy Gately
    Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity College Dublin, St James s Hospital, Dublin, Ireland Electronic address
    Clin Lung Cancer 15:58-66. 2014
  2. doi request reprint Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: a verification study
    K Gately
    Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity College Dublin, St James s Hospital, Dublin 8, Ireland
    Lung Cancer 75:217-22. 2012
  3. doi request reprint Design, construction, and analysis of cell line arrays and tissue microarrays for gene expression analysis
    Kathy Gately
    Department of Clinical Medicine, Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Dublin, Ireland
    Methods Mol Biol 784:139-53. 2011
  4. doi request reprint A role for IGF-1R-targeted therapies in small-cell lung cancer?
    Kathy Gately
    Department of Clinical Medicine, Trinity College Dublin, St James Hospital, Dublin 8, Ireland
    Clin Lung Cancer 12:38-42. 2011
  5. doi request reprint Clinical implication and prognostic significance of standardised uptake value of primary non-small cell lung cancer on positron emission tomography: analysis of 176 cases
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland Department of Thoracic Surgery, Chest Disease Hospital, Kuwait
    Eur J Cardiothorac Surg 34:892-7. 2008
  6. doi request reprint Mediastinal lymph node staging by means of positron emission tomography is less sensitive in elderly patients with non-small-cell lung cancer
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin, Ireland
    Clin Lung Cancer 9:39-43. 2008
  7. ncbi request reprint Pattern and predictors of occult mediastinal lymph node involvement in non-small cell lung cancer patients with negative mediastinal uptake on positron emission tomography
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
    Eur J Cardiothorac Surg 33:104-9. 2008
  8. doi request reprint Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer
    Mary Clare Cathcart
    Department of Clinical Medicine, Translational Cancer Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland
    Cancer 117:5121-32. 2011
  9. pmc Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
    Mary Clare Cathcart
    Department of Surgery, Institute of Molecular Medicine, Trinity Health Sciences Centre, St James s Hospital, Dublin 8, Ireland
    Mol Cancer 10:25. 2011
  10. ncbi request reprint Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: analysis of 1,145 lymph nodes
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
    Lung Cancer 60:62-8. 2008

Detail Information

Publications14

  1. doi request reprint High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer
    Kathy Gately
    Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity College Dublin, St James s Hospital, Dublin, Ireland Electronic address
    Clin Lung Cancer 15:58-66. 2014
    ..This study examines the expression of both receptors and their prognostic significance in surgically resected non-small-cell lung cancer (NSCLC)...
  2. doi request reprint Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: a verification study
    K Gately
    Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity College Dublin, St James s Hospital, Dublin 8, Ireland
    Lung Cancer 75:217-22. 2012
    ..The aim of this study was to verify the above study by examining the angioinvasion and mTOR expression profile in a cohort of early stage NSCLC patients and correlate the results to patient clinico-pathological data and survival...
  3. doi request reprint Design, construction, and analysis of cell line arrays and tissue microarrays for gene expression analysis
    Kathy Gately
    Department of Clinical Medicine, Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Dublin, Ireland
    Methods Mol Biol 784:139-53. 2011
    ..This chapter provides detailed methods for CMA/TMA design, construction and analysis with in-depth notes on all technical aspects including tips to deal with common pitfalls the user may encounter...
  4. doi request reprint A role for IGF-1R-targeted therapies in small-cell lung cancer?
    Kathy Gately
    Department of Clinical Medicine, Trinity College Dublin, St James Hospital, Dublin 8, Ireland
    Clin Lung Cancer 12:38-42. 2011
    ..The insulin-like growth factor-1 receptor (IGF-1R) is an autocrine growth factor and an attractive therapeutic target in many solid tumors, but particularly in lung cancer...
  5. doi request reprint Clinical implication and prognostic significance of standardised uptake value of primary non-small cell lung cancer on positron emission tomography: analysis of 176 cases
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland Department of Thoracic Surgery, Chest Disease Hospital, Kuwait
    Eur J Cardiothorac Surg 34:892-7. 2008
    ..We sought to assess the clinical implication and prognostic significance of maximum standardised uptake value (SUV(max)) of primary non-small cell lung cancer (NSCLC) staged by integrated PET-CT...
  6. doi request reprint Mediastinal lymph node staging by means of positron emission tomography is less sensitive in elderly patients with non-small-cell lung cancer
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin, Ireland
    Clin Lung Cancer 9:39-43. 2008
    ..We sought to identify the impact of age on the sensitivity and specificity of integrated positron emission tomography/computed tomography (PET-CT; CT) on mediastinal lymph node staging of patients with non-small-cell lung cancer (NSCLC)...
  7. ncbi request reprint Pattern and predictors of occult mediastinal lymph node involvement in non-small cell lung cancer patients with negative mediastinal uptake on positron emission tomography
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
    Eur J Cardiothorac Surg 33:104-9. 2008
    ....
  8. doi request reprint Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer
    Mary Clare Cathcart
    Department of Clinical Medicine, Translational Cancer Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James Hospital, Dublin, Ireland
    Cancer 117:5121-32. 2011
    ..Prostacyclin synthase (PGIS) metabolizes prostaglandin H(2), into prostacyclin. This study aimed to determine the expression profile of PGIS in nonsmall cell lung cancer (NSCLC) and examine potential mechanisms involved in PGIS regulation...
  9. pmc Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
    Mary Clare Cathcart
    Department of Surgery, Institute of Molecular Medicine, Trinity Health Sciences Centre, St James s Hospital, Dublin 8, Ireland
    Mol Cancer 10:25. 2011
    ..TXS inhibition induces cell death in-vitro, providing a rationale for therapeutic intervention. We aimed to determine the expression profile of TXS in NSCLC and if it is prognostic and/or a survival factor in the disease...
  10. ncbi request reprint Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: analysis of 1,145 lymph nodes
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
    Lung Cancer 60:62-8. 2008
    ..We sought to assess if PET-CT is uniformly accurate among enlarged and non-enlarged lymph nodes...
  11. doi request reprint Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells
    Steven G Gray
    Department of Clinical Medicine, Thoracic Oncology Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Dublin 8, Ireland
    Clin Lung Cancer 9:367-74. 2008
    ..Finally, hypoxia was demonstrated to downregulate IRS5/DOK4 expression. This expression was restored by TSA. The clinical relevance of altered IRS5/DOK4 expression in NSCLC requires further evaluation...
  12. doi request reprint The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC
    Kathy Gately
    Department of Clinical Medicine, Institute of Molecular Medicine, St James s Hospital, Dublin, Ireland
    J Clin Pathol 65:1-7. 2012
    ....
  13. ncbi request reprint Factors causing inaccurate staging of mediastinal nodal involvement in non-small cell lung cancer patients staged by positron emission tomography
    Nael Al-Sarraf
    Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
    Interact Cardiovasc Thorac Surg 6:350-3. 2007
    ..Vigilance of such factors may improve the accuracy of PET-CT in staging mediastinal lymph nodes. Histological confirmation should always be sought...
  14. doi request reprint Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC
    Susan Heavey
    Thoracic Oncology Research, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James s Hospital, Dublin 8, Ireland Electronic address
    Cancer Treat Rev 40:445-56. 2014
    ..The identification of appropriate patient cohorts who will benefit from PI3K co-targeted inhibition strategies will be key to the success of these inhibitors. ..