Mary Cannon

Summary

Affiliation: Royal College of Surgeons in Ireland
Country: Ireland

Publications

  1. doi request reprint Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 9, Ireland
    Am J Psychiatry 166:1025-30. 2009
  2. pmc Are screening instruments valid for psychotic-like experiences? A validation study of screening questions for psychotic-like experiences using in-depth clinical interview
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
    Schizophr Bull 37:362-9. 2011
  3. pmc Reduced duration mismatch negativity in adolescents with psychotic symptoms: further evidence for mismatch negativity as a possible biomarker for vulnerability to psychosis
    Jennifer R Murphy
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    BMC Psychiatry 13:45. 2013
  4. ncbi request reprint Risk for schizophrenia--broadening the concepts, pushing back the boundaries
    Mary Cannon
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Schizophr Res 79:5-13. 2005
  5. pmc Neurocognition in the extended psychosis phenotype: performance of a community sample of adolescents with psychotic symptoms on the MATRICS neurocognitive battery
    Ian Kelleher
    Royal College of Surgeons in Ireland, Dublin 9, Ireland
    Schizophr Bull 39:1018-26. 2013
  6. doi request reprint Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Br J Psychiatry 201:26-32. 2012
  7. doi request reprint Psychotic symptoms and population risk for suicide attempt: a prospective cohort study
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin
    JAMA Psychiatry 70:940-8. 2013
  8. doi request reprint Neurocognitive performance of a community-based sample of young people at putative ultra high risk for psychosis: support for the processing speed hypothesis
    Ian Kelleher
    Royal College of Surgeons in Ireland, Department of Psychiatry, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
    Cogn Neuropsychiatry 18:9-25. 2013
  9. ncbi request reprint Predicting risk and the emergence of schizophrenia
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Psychiatr Clin North Am 35:585-612. 2012
  10. pmc Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Schizophr Bull 38:239-46. 2012

Collaborators

Detail Information

Publications40

  1. doi request reprint Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 9, Ireland
    Am J Psychiatry 166:1025-30. 2009
    ..The authors sought to determine whether prenatal exposure to infection and a positive family history of psychotic disorders interact synergistically to increase the risk of later developing schizophrenia...
  2. pmc Are screening instruments valid for psychotic-like experiences? A validation study of screening questions for psychotic-like experiences using in-depth clinical interview
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
    Schizophr Bull 37:362-9. 2011
    ..Our results suggest that it may be possible to screen the general adolescent population for psychotic-like experiences with a high degree of accuracy using a short self-report questionnaire...
  3. pmc Reduced duration mismatch negativity in adolescents with psychotic symptoms: further evidence for mismatch negativity as a possible biomarker for vulnerability to psychosis
    Jennifer R Murphy
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    BMC Psychiatry 13:45. 2013
    ....
  4. ncbi request reprint Risk for schizophrenia--broadening the concepts, pushing back the boundaries
    Mary Cannon
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Schizophr Res 79:5-13. 2005
    ....
  5. pmc Neurocognition in the extended psychosis phenotype: performance of a community sample of adolescents with psychotic symptoms on the MATRICS neurocognitive battery
    Ian Kelleher
    Royal College of Surgeons in Ireland, Dublin 9, Ireland
    Schizophr Bull 39:1018-26. 2013
    ..This group likely demonstrates some of the earliest cognitive impairments associated with psychosis vulnerability...
  6. doi request reprint Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Br J Psychiatry 201:26-32. 2012
    ..There has been a lack of research, however, on the immediate clinicopathological significance of psychotic symptoms in adolescence...
  7. doi request reprint Psychotic symptoms and population risk for suicide attempt: a prospective cohort study
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin
    JAMA Psychiatry 70:940-8. 2013
    ..Up to 1 million persons die by suicide annually. However, a lack of risk markers makes suicide risk assessment one of the most difficult areas of clinical practice...
  8. doi request reprint Neurocognitive performance of a community-based sample of young people at putative ultra high risk for psychosis: support for the processing speed hypothesis
    Ian Kelleher
    Royal College of Surgeons in Ireland, Department of Psychiatry, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
    Cogn Neuropsychiatry 18:9-25. 2013
    ..We wished to extend this research by conducting the first population-based assessment of prodromal syndromes and associated neurocognition...
  9. ncbi request reprint Predicting risk and the emergence of schizophrenia
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Psychiatr Clin North Am 35:585-612. 2012
    ..This article discusses those environmental risk factors for schizophrenia for which there is the largest evidence base...
  10. pmc Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Schizophr Bull 38:239-46. 2012
    ....
  11. doi request reprint Increased risk of schizophrenia from additive interaction between infant motor developmental delay and obstetric complications: evidence from a population-based longitudinal study
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
    Am J Psychiatry 168:1295-302. 2011
    ..Obstetric complications and developmental delay are well-established risk factors for schizophrenia. The authors investigated whether these risk factors interact in an additive manner to further increase risk for schizophrenia...
  12. pmc Relationship between the COMT-Val158Met and BDNF-Val66Met polymorphisms, childhood trauma and psychotic experiences in an adolescent general population sample
    Hugh Ramsay
    Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
    PLoS ONE 8:e79741. 2013
    ..We examined whether COMT or BDNF genotypes were associated with psychotic experiences or interacted with childhood trauma in predicting psychotic experiences...
  13. doi request reprint Structural and functional brain correlates of subclinical psychotic symptoms in 11-13 year old schoolchildren
    Sarah Jacobson
    School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland
    Neuroimage 49:1875-85. 2010
    ....
  14. doi request reprint Sudden death of father or sibling in early childhood increases risk for psychotic disorder
    Mary C Clarke
    Department of Psychiatry and Psychology, Royal College of Surgeons in Ireland, Dublin, Ireland
    Schizophr Res 143:363-6. 2013
    ..To determine if exposure to a severe, acute stressor during early development is associated with an increased incidence of schizophrenia and bipolar disorder compared to exposure to a chronic stressor...
  15. doi request reprint Language, motor and speed of processing deficits in adolescents with subclinical psychotic symptoms
    Mathieu M Blanchard
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 9, Ireland
    Schizophr Res 123:71-6. 2010
    ..We wished to investigate neuropsychological functioning in early adolescence in relation to reports of psychotic symptoms...
  16. pmc Chronic adolescent exposure to delta-9-tetrahydrocannabinol in COMT mutant mice: impact on indices of dopaminergic, endocannabinoid and GABAergic pathways
    Aine T Behan
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Neuropsychopharmacology 37:1773-83. 2012
    ..These findings illuminate how COMT deletion and adolescent cannabis use can interact to modulate the function of neurotransmitters systems implicated in schizophrenia...
  17. doi request reprint Evidence for shared susceptibility to epilepsy and psychosis: a population-based family study
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Biol Psychiatry 71:836-9. 2012
    ..Here we investigate shared familial vulnerability to psychotic illness and epilepsy in a family-based study...
  18. pmc Psychotic symptoms, functioning and coping in adolescents with mental illness
    Johanna Tw Wigman
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre Dublin, Dublin, Ireland
    BMC Psychiatry 14:97. 2014
    ..This paper aimed to address the question whether 1) psychotic symptoms are associated with poorer functioning and 2) whether poor coping moderated the association...
  19. doi request reprint Childhood trauma and psychosis in a prospective cohort study: cause, effect, and directionality
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons, Ireland
    Am J Psychiatry 170:734-41. 2013
    ..1) Does exposure to trauma predict incident psychotic experiences? 2) Does cessation of trauma predict cessation of psychotic experiences? 3) What is the direction of the relationship between childhood trauma and psychotic experiences?..
  20. doi request reprint Prevalence of DSM-IV mental disorders, deliberate self-harm and suicidal ideation in early adolescence: an Irish population-based study
    Helen Coughlan
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland Electronic address
    J Adolesc 37:1-9. 2014
    ..This study investigated the prevalence of DSM-IV Axis 1 mental disorders, deliberate self-harm and suicidal ideation in a sample of Irish adolescents aged 11-13 years...
  21. doi request reprint Associations between childhood trauma, bullying and psychotic symptoms among a school-based adolescent sample
    Ian Kelleher
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Br J Psychiatry 193:378-82. 2008
    ..However, little research has investigated whether those in this high-risk population have increased rates of exposure to traumatic events in childhood, as seen in patients who have a psychotic illness...
  22. pmc Is traumatic brain injury a risk factor for schizophrenia? A meta-analysis of case-controlled population-based studies
    Charlene Molloy
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Dublin 9, Ireland
    Schizophr Bull 37:1104-10. 2011
    ..Further epidemiological and neuroscientific studies to elucidate the mechanisms underlying this association are warranted...
  23. doi request reprint Language processing abnormalities in adolescents with psychotic-like experiences: an event related potential study
    Jennifer Murphy
    Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
    Schizophr Res 137:91-6. 2012
    ..The results of this study reveal electrophysiological evidence for receptive language deficits in adolescents with PLEs, suggesting that the earliest neurobiological changes underlying psychosis may be apparent in the adolescent period...
  24. pmc The prevalence of psychosis in epilepsy; a systematic review and meta-analysis
    Maurice J Clancy
    Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    BMC Psychiatry 14:75. 2014
    ..The aim of this study was to assess the prevalence of psychosis in epilepsy and to estimate the risk of psychosis among individuals with epilepsy compared with controls...
  25. ncbi request reprint Foetal brain development in offspring of women with psychosis
    Mary C Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, RCSI Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland
    Br J Psychiatry 190:445-6. 2007
    ..Overall, no significant differences were found between the high-risk and control groups. There was a non-significant trend in the adjusted analysis towards increased lateral ventricular width in the offspring of mothers with psychosis...
  26. pmc The role of obstetric events in schizophrenia
    Mary Catherine Clarke
    Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
    Schizophr Bull 32:3-8. 2006
  27. ncbi request reprint Neuropsychological performance at the age of 13 years and adult schizophreniform disorder: prospective birth cohort study
    Mary Cannon
    Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
    Br J Psychiatry 189:463-4. 2006
    ....
  28. doi request reprint Neuroanatomical correlates of psychosis in temporal lobe epilepsy: voxel-based morphometry study
    Frederick Sundram
    Department of Psychiatry, Education and Research Centre, Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin, Ireland
    Br J Psychiatry 197:482-92. 2010
    ..Temporal lobe epilepsy is associated with a significant risk of psychosis but there are only limited studies investigating the underlying neurobiology...
  29. pmc Chronic adolescent exposure to Δ-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes
    Colm M P O'Tuathaigh
    Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland
    Neuropsychopharmacology 35:2262-73. 2010
    ..These findings illuminate the interaction between genes and adverse environmental exposures over a particular stage of development in the expression of the psychosis phenotype...
  30. ncbi request reprint Obstetric complications and schizophrenia: historical and meta-analytic review
    Mary Cannon
    Division of Psychological Medicine P063, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Am J Psychiatry 159:1080-92. 2002
    ..The authors trace the evolution of this literature through different methods and carry out a quantitative review of the results from prospective, population-based studies...
  31. ncbi request reprint Pathways to schizophrenia: the impact of environmental factors
    Oliver D Howes
    Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Int J Neuropsychopharmacol 7:S7-S13. 2004
    ..Thus, stresses, such as drug use and social adversity, in adolescence or early adult life may propel the neurodevelopmentally impaired individual over a threshold into frank psychosis...
  32. ncbi request reprint Perinatal and childhood risk factors for later criminality and violence in schizophrenia. Longitudinal, population-based study
    Mary Cannon
    Division of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London
    Br J Psychiatry 180:496-501. 2002
    ..Obstetric complications, neuromotor problems and intellectual deficits have variously been reported as increasing the risk for criminality in the general population...
  33. pmc Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
    Louise Arseneault
    SGDP Research Centre, King s College, London
    BMJ 325:1212-3. 2002
  34. ncbi request reprint Causal association between cannabis and psychosis: examination of the evidence
    Louise Arseneault
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Br J Psychiatry 184:110-7. 2004
    ..Controversy remains as to whether cannabis acts as a causal risk factor for schizophrenia or other functional psychotic illnesses...
  35. ncbi request reprint A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
    Robin M Murray
    Institute of Psychiatry, Psychological Medicine, Denmark Hill, DeCrespigny Park, London SE5 8AF, UK
    Schizophr Res 71:405-16. 2004
    ....
  36. ncbi request reprint Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction
    Avshalom Caspi
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Biol Psychiatry 57:1117-27. 2005
    ..The vast majority of cannabis users do not develop psychosis, however, prompting us to hypothesize that some people are genetically vulnerable to the deleterious effects of cannabis...
  37. ncbi request reprint Premorbid intellectual functioning in bipolar disorder and schizophrenia: results from a cohort study of male conscripts
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Kuopio, Niuvanniemi Hospital, FIN 70240 Kuopio, Finland
    Am J Psychiatry 162:1904-10. 2005
    ..In this study, premorbid intellectual ability was investigated in individuals with bipolar disorder, schizophrenia, or other psychoses...
  38. ncbi request reprint Exposure to obstetric complications and subsequent development of bipolar disorder: Systematic review
    Jan Scott
    PO 96, Department of Psychological Medicine, Institute of Psychiatry, London SE5 8AF, UK
    Br J Psychiatry 189:3-11. 2006
    ..Research has suggested an association between obstetric complications and bipolar disorder. However, no quantitative evaluation has been made of the pooled data from existing studies...
  39. doi request reprint The validity of schizophrenia diagnosis in the Finnish Hospital Discharge Register: findings from a 10-year birth cohort sample
    Johanna Pihlajamaa
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Nord J Psychiatry 62:198-203. 2008
    ....
  40. ncbi request reprint Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort
    Mary Cannon
    Division of Psychological Medicine, Institute of Psychiatry, London, England
    Arch Gen Psychiatry 59:449-56. 2002
    ..It is not known, however, whether childhood developmental impairment is specific to schizophrenia or is merely a marker for a range of psychiatric outcomes...