Research Topics
Species | Sean ComminsSummaryAffiliation: National University of Ireland Country: Ireland Publications
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Publications
Massed but not spaced training impairs spatial memorySean Commins
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Behav Brain Res 139:215-23. 2003..Results are discussed in terms of poor encoding of the environment leading to poor retention...
Relating derived relations as a model of analogical reasoning: reaction times and event-related potentialsDermot Barnes-Holmes
Department of Psychology, National University of Ireland, Maynooth, Co Kildare
J Exp Anal Behav 84:435-51. 2005..These findings strengthen the validity of the RFT model of analogical reasoning and supplement the behavior-analytic approach to analogy based on the relating of derived relations...
Differences in cue-dependent spatial navigation may be revealed by in-depth swimming analysisDeirdre R Harvey
Department of Psychology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
Behav Processes 82:190-7. 2009....- High-resolution ERP mapping of cortical activation related to implicit object-location memoryJonathan S Murphy
Dept of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Biol Psychol 82:234-45. 2009..Hemispheric differences in parietal componentry dependant on sex of participant were also observed and are discussed in relation to differential strategies... - Frequency-dependent changes in synaptic plasticity and brain-derived neurotrophic factor (BDNF) expression in the CA1 to perirhinal cortex projectionJohn Kealy
Department of Psychology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
Brain Res 1326:51-61. 2010..These findings suggest that the CA1 to perirhinal cortex projection is electrophysiologically excitatory in nature and that changes in BDNF levels in this projection may not be predictive of changes in synaptic plasticity... - A possible role for protein synthesis, extracellular signal-regulated kinase, and brain-derived neurotrophic factor in long-term spatial memory retention in the water mazeAnne Marie T McGauran
Department of Psychology, National University of Ireland Maynooth, Co Kildare, Ireland
Behav Neurosci 122:805-15. 2008..Our results demonstrate a role of protein synthesis in spatial memory retention, along with a possible relationship between protein synthesis and hippocampal BDNF/ERK expression... - The effects of overtraining in the Morris water maze on allocentric and egocentric learning strategies in ratsJohn Kealy
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Behav Brain Res 192:259-63. 2008..Further, with overtraining animals do not always switch from allocentric to an egocentric learning strategy perhaps challenging suggestions of a stored hierarchy of strategies... - Antagonism of glutamate receptors in the CA1 to perirhinal cortex projection prevents long-term potentiation and attenuates levels of brain-derived neurotrophic factorJohn Kealy
Department of Psychology, National University of Ireland, Co Kildare, Ireland
Brain Res 1265:53-64. 2009..This molecular and electrophysiological data suggests that LTP in the CA1-perirhinal cortex projection may require activation of postsynaptic AMPA/kainate receptors in order to sustain LTP... - Emergence of an egocentric cue guiding and allocentric inferring strategy that mirrors hippocampal brain-derived neurotrophic factor (BDNF) expression in the Morris water mazeDeirdre R Harvey
Department of Psychology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
Neurobiol Learn Mem 89:462-79. 2008..We also demonstrate that behavioural changes, towards a more allocentric strategy, are reflected in increases in hippocampal brain-derived neurotrophic factor... - The subiculum to entorhinal cortex projection is capable of sustaining both short- and long-term plastic changesSarah Craig
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Behav Brain Res 174:281-8. 2006..Finally we show that PPF changes after LTP and LTD, suggesting that a presynaptic mechanism may be involved in both of these pathways... - The rat perirhinal cortex: A review of anatomy, physiology, plasticity, and functionJohn Kealy
Department of Psychology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
Prog Neurobiol 93:522-48. 2011.... - Retention of cue-based associations in the water maze is time-dependent and sensitive to disruption by rotating the starting positionAnne-Marie T McGauran
Department of Psychology, National University of Ireland, Maynooth, Co. Kildare, Ireland
Behav Brain Res 151:255-66. 2004..We suggest that the association between the configuration of distal cues and platform location is retained in memory but the association is fragile and sensitive to disruption... - Plastic and metaplastic changes in the CA1 and subicular projections to the entorhinal cortexSarah Craig
Department of Psychology, National University of Ireland, Maynooth, Maynooth, Co Kildare, Ireland
Brain Res 1147:124-39. 2007.... - Vestibular influence on water maze retention: transient whole body rotations improve the accuracy of the cue-based retention strategyAnne-Marie T McGauran
Department of Psychology, National University of Ireland, Maynooth, Co. Kildare, Ireland
Behav Brain Res 158:183-7. 2005..In experiment 2, we demonstrate that vestibular rotation eliminates this inaccuracy. These experiments highlight the importance of both cue and vestibular information for accurate retention of the water maze... - Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CA1 to the entorhinal cortexSarah Craig
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Neurosci Res 53:140-6. 2005..These findings should provide insight into the hippocampal function in memory formation... - Long-term retention and overshadowing of proximal and distal cues following habituation in an object exploration taskSarah Craig
Department of Psychology, National University of Ireland, Maynooth, Co. Kildare, Ireland
Behav Processes 68:117-28. 2005..In Study 2, we examined the effect of overshadowing and demonstrate that proximal visual spatial cues can overshadow distal spatial cues if a conflict arises between both set... - Interleukin-10 (IL-10) but not Lipopolysaccharide (LPS) produces increased motor activity and abnormal exploratory patterns while impairing spatial learning in Balb/c miceDeirdre Harvey
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
Physiol Behav 87:842-7. 2006..Interestingly, a single injection of IL-10 produces abnormal patterns of exploration, a general increase in activity and abnormal patterns of habituation... - Derived stimulus relations, semantic priming, and event-related potentials: testing a behavioral theory of semantic networksDermot Barnes-Holmes
Department of Psychology, National University of Ireland, Maynooth, Co Kildare, Ireland
J Exp Anal Behav 84:417-33. 2005..The findings support the argument that derived equivalence relations provides a useful preliminary model of semantic relations... - Imaging spatial learning in the brain using immediate early genes: insights, opportunities and limitationsDaniel N Barry
Department of Psychology, National University of Ireland Maynooth, Maynooth, Co Kildare, Ireland
Rev Neurosci 22:131-42. 2011..Further investigation of the time course and dynamics of IEG expression during learning and retention is required to fully interpret observed results... - Subtle memory and attentional deficits revealed in an Irish stroke patient sample using domain-specific cognitive tasksJoseph T Duffin
Department of Psychology, National University of Ireland Maynooth, Maynooth, Ireland
J Clin Exp Neuropsychol 34:864-75. 2012..We recommend a standardized multidomain cognitive assessment and propose that cognitive deficits post stroke require in-depth assessment to inform patient-orientated rehabilitation... - Physiological evidence for a possible projection from dorsal subiculum to hippocampal area CA1Sean Commins
Department of Psychology, NUI, Maynooth, Co. Kildare, Ireland
Exp Brain Res 146:155-60. 2002..We were unable to induce long-term potentiation following high-frequency stimulation, but were able to induce short-term potentiation... - Cyclooxygenase inhibition attenuates endotoxin-induced spatial learning deficits, but not an endotoxin-induced blockade of long-term potentiationKendra N Shaw
Department of Psychology and Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland
Brain Res 1038:231-7. 2005..Paradoxically compared to the behavioral findings treatment with ibuprofen does not attenuate the LPS-induced impairment in LTP or BDNF concentration in tetanized tissue... - Deficits in spatial learning and synaptic plasticity induced by the rapid and competitive broad-spectrum cyclooxygenase inhibitor ibuprofen are reversed by increasing endogenous brain-derived neurotrophic factorKendra N Shaw
Department of Psychology and Trinity College Institute of Neuroscience, Trinity College, Dublin 2, Ireland
Eur J Neurosci 17:2438-46. 2003..Thus, COX plays a previously undescribed, permissive role in synaptic plasticity and spatial learning via a BDNF-associated mechanism...