Gavin J Blake

Summary

Affiliation: Mater Misericordiae Hospital
Country: Ireland

Publications

  1. ncbi request reprint Blood pressure, C-reactive protein, and risk of future cardiovascular events
    Gavin J Blake
    Center for Cardiovascular Disease Prevention and the Donald W Reynolds Center for Cardiovascular Research, Boston, Mass, USA
    Circulation 108:2993-9. 2003
  2. ncbi request reprint C-reactive protein and the risk of developing hypertension
    Howard D Sesso
    Department of Medicine, Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215 1204, USA
    JAMA 290:2945-51. 2003
  3. ncbi request reprint Potential cost-effectiveness of C-reactive protein screening followed by targeted statin therapy for the primary prevention of cardiovascular disease among patients without overt hyperlipidemia
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Med 114:485-94. 2003
  4. ncbi request reprint Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
    Circulation 106:1930-7. 2002
  5. ncbi request reprint Hemoglobin A1c level and future cardiovascular events among women
    Gavin J Blake
    Cardiovascular Division, The Center for Cardiovascular Disease Prevention, and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 164:757-61. 2004
  6. ncbi request reprint Inflammatory biomarkers of the patient with myocardial insufficiency
    Gavin J Blake
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Crit Care 9:369-74. 2003
  7. ncbi request reprint C-reactive protein: a surrogate risk marker or mediator of atherothrombosis?
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1250-2. 2003
  8. ncbi request reprint Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure
    Subroto Paul
    Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 79:701-3. 2005
  9. ncbi request reprint Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRI
    Gavin J Blake
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 23:e11-4. 2003
  10. ncbi request reprint C-reactive protein and other inflammatory risk markers in acute coronary syndromes
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, the Leducq Center for Cardiovascular Research, and the Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 41:37S-42S. 2003

Detail Information

Publications16

  1. ncbi request reprint Blood pressure, C-reactive protein, and risk of future cardiovascular events
    Gavin J Blake
    Center for Cardiovascular Disease Prevention and the Donald W Reynolds Center for Cardiovascular Research, Boston, Mass, USA
    Circulation 108:2993-9. 2003
    ..Accumulating data suggest a link between blood pressure and vascular inflammation...
  2. ncbi request reprint C-reactive protein and the risk of developing hypertension
    Howard D Sesso
    Department of Medicine, Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215 1204, USA
    JAMA 290:2945-51. 2003
    ..Although it has been hypothesized that hypertension is in part an inflammatory disorder, clinical data linking inflammation with incident hypertension are scarce...
  3. ncbi request reprint Potential cost-effectiveness of C-reactive protein screening followed by targeted statin therapy for the primary prevention of cardiovascular disease among patients without overt hyperlipidemia
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Med 114:485-94. 2003
    ..However, no cost-effectiveness analyses have been performed to assist in determining whether large-scale randomized trials are merited to test this hypothesis...
  4. ncbi request reprint Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02215, USA
    Circulation 106:1930-7. 2002
    ..Nuclear magnetic resonance (NMR) offers an alternative, spectroscopic means of quantifying LDL and of measuring LDL particle size...
  5. ncbi request reprint Hemoglobin A1c level and future cardiovascular events among women
    Gavin J Blake
    Cardiovascular Division, The Center for Cardiovascular Disease Prevention, and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 164:757-61. 2004
    ..We sought to test this hypothesis prospectively in a cohort of women without overt cardiovascular disease...
  6. ncbi request reprint Inflammatory biomarkers of the patient with myocardial insufficiency
    Gavin J Blake
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Crit Care 9:369-74. 2003
    ..Furthermore, the predictive value of inflammatory markers is independent of traditional risk markers such as lipid levels, or cardiac troponin levels among those with acute coronary syndromes...
  7. ncbi request reprint C-reactive protein: a surrogate risk marker or mediator of atherothrombosis?
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1250-2. 2003
  8. ncbi request reprint Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure
    Subroto Paul
    Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 79:701-3. 2005
    ..This case illustrates the importance of collaboration between interventional cardiologists and cardiac surgeons in the treatment of complex postinfarction ventricular septal defects...
  9. ncbi request reprint Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRI
    Gavin J Blake
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 23:e11-4. 2003
    ..We tested the hypothesis that plasma levels of soluble CD40 ligand are elevated in patients with evidence of a lipid pool on high-resolution magnetic resonance imaging (MRI) of carotid stenoses...
  10. ncbi request reprint C-reactive protein and other inflammatory risk markers in acute coronary syndromes
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, the Leducq Center for Cardiovascular Research, and the Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 41:37S-42S. 2003
    ..Furthermore, the benefits of lifestyle modification and drug therapy with aspirin or statins may be most marked among those with elevated CRP levels...
  11. ncbi request reprint Effect of pravastatin on LDL particle concentration as determined by NMR spectroscopy: a substudy of a randomized placebo controlled trial
    Gavin J Blake
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Eur Heart J 24:1843-7. 2003
    ..We sought to determine the effect of randomization to pravastatin therapy on LDL particle concentration-NMR, among a primary prevention population...
  12. ncbi request reprint Projected life-expectancy gains with statin therapy for individuals with elevated C-reactive protein levels
    Gavin J Blake
    Center for Cardiovascular Disease Prevention, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 40:49-55. 2002
    ..We sought to estimate the potential gains in life expectancy achieved with statin therapy for individuals without overt hyperlipidemia but with elevated C-reactive protein (CRP) levels...
  13. ncbi request reprint Rescue percutaneous coronary intervention following coronary artery bypass graft--a descriptive analysis of the changing interface between interventional cardiologist and cardiac surgeon
    Mark R Adams
    Department of Cardiology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Cardiol 25:280-6. 2002
    ..We sought to confirm this decrease in the need for rescue CABG following failed PCI and to examine trends in the utilization of rescue PCI following failed CABG...
  14. ncbi request reprint C-reactive protein, subclinical atherosclerosis, and risk of cardiovascular events
    Gavin J Blake
    Arterioscler Thromb Vasc Biol 22:1512-3. 2002
  15. ncbi request reprint Influence of race on death and ischemic complications in patients with non-ST-elevation acute coronary syndromes despite modern, protocol-guided treatment
    Marc S Sabatine
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115
    Circulation 111:1217-24. 2005
    ..Whether the disparate outcomes exist independently of potential biases in treatment patterns remains unclear...
  16. doi request reprint Long-term follow-up of the West of Scotland Coronary Prevention Study
    John W McEvoy
    N Engl J Med 358:193; author reply 194-5. 2008