Research Topics
| Gavin J BlakeSummaryAffiliation: Mater Misericordiae Hospital Country: Ireland Publications
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Detail Information
Publications
Blood pressure, C-reactive protein, and risk of future cardiovascular eventsGavin J Blake
Center for Cardiovascular Disease Prevention and the Donald W Reynolds Center for Cardiovascular Research, Boston, Mass, USA
Circulation 108:2993-9. 2003..Accumulating data suggest a link between blood pressure and vascular inflammation...
C-reactive protein and the risk of developing hypertensionHoward D Sesso
Department of Medicine, Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215 1204, USA
JAMA 290:2945-51. 2003..Although it has been hypothesized that hypertension is in part an inflammatory disorder, clinical data linking inflammation with incident hypertension are scarce...
Potential cost-effectiveness of C-reactive protein screening followed by targeted statin therapy for the primary prevention of cardiovascular disease among patients without overt hyperlipidemiaGavin J Blake
Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Med 114:485-94. 2003....
Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in womenGavin J Blake
Center for Cardiovascular Disease Prevention, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02215, USA
Circulation 106:1930-7. 2002..However, the magnitude of predictive value of LDL particle concentration (NMR) was not substantively different from that of the total cholesterol to HDL cholesterol ratio and was less than that of C-reactive protein...
Hemoglobin A1c level and future cardiovascular events among womenGavin J Blake
Cardiovascular Division, The Center for Cardiovascular Disease Prevention, and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Arch Intern Med 164:757-61. 2004..We sought to test this hypothesis prospectively in a cohort of women without overt cardiovascular disease...
Inflammatory biomarkers of the patient with myocardial insufficiencyGavin J Blake
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Curr Opin Crit Care 9:369-74. 2003..Furthermore, the predictive value of inflammatory markers is independent of traditional risk markers such as lipid levels, or cardiac troponin levels among those with acute coronary syndromes...
C-reactive protein: a surrogate risk marker or mediator of atherothrombosis?Gavin J Blake
Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA
Am J Physiol Regul Integr Comp Physiol 285:R1250-2. 2003
Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closureSubroto Paul
Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Ann Thorac Surg 79:701-3. 2005..This case illustrates the importance of collaboration between interventional cardiologists and cardiac surgeons in the treatment of complex postinfarction ventricular septal defects...
Soluble CD40 ligand levels indicate lipid accumulation in carotid atheroma: an in vivo study with high-resolution MRIGavin J Blake
Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass, USA
Arterioscler Thromb Vasc Biol 23:e11-4. 2003....
C-reactive protein and other inflammatory risk markers in acute coronary syndromesGavin J Blake
Center for Cardiovascular Disease Prevention, the Leducq Center for Cardiovascular Research, and the Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 41:37S-42S. 2003..Furthermore, the benefits of lifestyle modification and drug therapy with aspirin or statins may be most marked among those with elevated CRP levels...
Effect of pravastatin on LDL particle concentration as determined by NMR spectroscopy: a substudy of a randomized placebo controlled trialGavin J Blake
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Eur Heart J 24:1843-7. 2003..We sought to determine the effect of randomization to pravastatin therapy on LDL particle concentration-NMR, among a primary prevention population...
Projected life-expectancy gains with statin therapy for individuals with elevated C-reactive protein levelsGavin J Blake
Center for Cardiovascular Disease Prevention, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Am Coll Cardiol 40:49-55. 2002..This analysis supports a crucial need for direct intervention trials aimed at subjects with elevated CRP levels...
Rescue percutaneous coronary intervention following coronary artery bypass graft--a descriptive analysis of the changing interface between interventional cardiologist and cardiac surgeonMark R Adams
Department of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Clin Cardiol 25:280-6. 2002....
C-reactive protein, subclinical atherosclerosis, and risk of cardiovascular eventsGavin J Blake
Arterioscler Thromb Vasc Biol 22:1512-3. 2002
Influence of race on death and ischemic complications in patients with non-ST-elevation acute coronary syndromes despite modern, protocol-guided treatmentMarc S Sabatine
TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115
Circulation 111:1217-24. 2005..Whether the disparate outcomes exist independently of potential biases in treatment patterns remains unclear...
Long-term follow-up of the West of Scotland Coronary Prevention StudyJohn W McEvoy
N Engl J Med 358:193; author reply 194-5. 2008
