Research Topics
Species | Shane KilleenSummaryCountry: Ireland Publications
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Detail Information
Publications
Daily diurnal variation in admissions for ruptured abdominal aortic aneurysmsShane Killeen
Department of Surgery, Cork University Hospital, Cork, Ireland
World J Surg 31:1869-71. 2007..It also demonstrates a diurnal variation. The purpose of this study was to determine if rupture of an abdominal aortic aneurysm (RAAA) exhibits a diurnal variation...
Mycotic aneurysm of the popliteal artery secondary to Streptococus pneumoniae: a case report and review of the literatureShane D Killeen
Departments of General Surgery, Cork University Hospital, Wilton, Cork, Ireland
J Med Case Reports 3:117. 2009..Definitive treatment generally utilizes surgical intervention with excision and reconstruction using autologous vein graft. Prolonged targeted antibiotic therapy is an important adjuvant...
Inhibition of urokinase plasminogen activator with a novel enzyme inhibitor, WXC-340, ameliorates endotoxin and surgery-accelerated growth of murine metastasesS D Killeen
Department of Surgery, Cork University Hospital, Cork, Ireland 2 2Department of Surgery, University College Cork, Cork, Ireland
Br J Cancer 96:262-8. 2007..Perioperative u-PA inhibition with WXC-340 may represent a novel therapeutic paradigm...
Provider volume and outcomes for abdominal aortic aneurysm repair, carotid endarterectomy, and lower extremity revascularization proceduresShane D Killeen
Department of Academic Surgery, National University of Ireland NUI University College Cork UCC, Cork University Hospital, Cork, Ireland
J Vasc Surg 45:615-26. 2007..Although a large number of studies assess the relationship between volume and outcome, a single contemporary compilation of such studies is lacking...
The urokinase plasminogen activator system in cancer: a putative therapeutic target?S Killeen
Department of Surgery, Kerry General Hospital, Tralee, Co Kerry, Ireland
Drug News Perspect 21:107-16. 2008..This review examines the role of the uPA system in tumor invasion and metastasis and assess the various therapeutic modalities developed to selectively exploit this system...
Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator systemS D Killeen
Department of Academic Surgery, Cork University Hospital and University College Cork, Cork, Ireland
Br J Cancer 100:1589-602. 2009..LPS promotes tumour cell ECM adhesion and invasion through activation of the u-PA system in a TLR-4- and NF-kappaB-dependent manner...
Gastric cancer-related information on the Internet: incomplete, poorly accessible, and overly commercialShane Killeen
Department of Surgery, Kerry General Hospital, Tralee, Co Kerry, Ireland
Am J Surg 201:171-8. 2011..Patients increasingly use the Internet for gastric cancer information. However, the quality of the information is questionable. We evaluated the accuracy, completeness, accessibility, reliability, and readability of gastric cancer websites...
Atmospheric pressure variations and abdominal aortic aneurysm ruptureS D Killeen
Department of Surgery, Cork University Hospital, Cork, Ireland
Ir J Med Sci 177:217-20. 2008..Ruptured abdominal aortic aneurysm (RAAA) presents with increased frequency in the winter and spring months. Seasonal changes in atmospheric pressure mirrors this pattern...
Mechanisms driving local breast cancer recurrence in a model of breast-conserving surgeryMyles J Smith
Department of Academic Surgery, Cork University Hospital, Cork, Ireland
Ann Surg Oncol 15:2954-64. 2008..We aimed to identify mechanisms driving local recurrence in a model of breast-conserving surgery (BCS) for breast cancer...
