Phillipe Taupin

Summary

Affiliation: Dublin City University
Country: Ireland

Publications

  1. doi Brevetoxin derivative compounds for stimulating neuronal growth: University of North Carolina at Wilmington: WO2008131411
    Phillipe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:269-74. 2009
  2. doi Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:523-7. 2009
  3. ncbi Neurogenic drugs and compounds
    Philippe Taupin
    School of Biotechnology, Dublin City University, Dublin, Ireland
    Recent Pat CNS Drug Discov 5:253-7. 2010
  4. pmc Potential of neural stem cells for the treatment of brain tumors
    P Taupin
    Fighting Blindness Vision Research Institute
    Clin Med Oncol 2:451-4. 2008
  5. doi Magnetic resonance imaging for monitoring neurogenesis in the adult hippocampus
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin, 9, Ireland 353 01 700 5284 353 01 700 5412
    Expert Opin Med Diagn 3:211-6. 2009
  6. ncbi Adult neurogenesis and neural stem cells as a model for the discovery and development of novel drugs
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland 01 700 7058
    Expert Opin Drug Discov 5:921-5. 2010
  7. doi Thirteen compounds promoting oligodendrocyte progenitor cell differentiation and remyelination for treating multiple sclerosis: WO2010054307
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 20:1767-73. 2010
  8. doi Antibodies against CD20 (rituximab) for treating multiple sclerosis: US20100233121
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:111-4. 2011
  9. ncbi Neurogenesis, NSCs, pathogenesis and therapies for Alzheimer's disease
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Front Biosci (Schol Ed) 3:178-90. 2011
  10. ncbi Neurogenic drugs and compounds to treat CNS diseases and disorders
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Cent Nerv Syst Agents Med Chem 11:35-7. 2011

Detail Information

Publications27

  1. doi Brevetoxin derivative compounds for stimulating neuronal growth: University of North Carolina at Wilmington: WO2008131411
    Phillipe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:269-74. 2009
    ....
  2. doi Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:523-7. 2009
    ....
  3. ncbi Neurogenic drugs and compounds
    Philippe Taupin
    School of Biotechnology, Dublin City University, Dublin, Ireland
    Recent Pat CNS Drug Discov 5:253-7. 2010
    ..Here, we reviewed and discussed recent patents on neurogenic drugs and compounds, particularly nootropic agents and apigenin and related compounds...
  4. pmc Potential of neural stem cells for the treatment of brain tumors
    P Taupin
    Fighting Blindness Vision Research Institute
    Clin Med Oncol 2:451-4. 2008
    ..It is proposed to combine gene therapy and cellular therapy to treat brain cancers. Hence, neural progenitor and stem cells provide new opportunities for the treatment of brain cancers...
  5. doi Magnetic resonance imaging for monitoring neurogenesis in the adult hippocampus
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin, 9, Ireland 353 01 700 5284 353 01 700 5412
    Expert Opin Med Diagn 3:211-6. 2009
    ..The application claims the imaging of the DG of patients by MRI as a paradigm to monitor neurogenesis and identify treatments involving stimulation of neurogenesis...
  6. ncbi Adult neurogenesis and neural stem cells as a model for the discovery and development of novel drugs
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland 01 700 7058
    Expert Opin Drug Discov 5:921-5. 2010
    ..Adult NSCs represent a model to discover and develop novel drugs for treating neurological diseases and disorders. These drugs may also have potential for regenerative medicine and the treatment of brain tumors...
  7. doi Thirteen compounds promoting oligodendrocyte progenitor cell differentiation and remyelination for treating multiple sclerosis: WO2010054307
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 20:1767-73. 2010
    ..Objective: It aims at identifying and characterizing compounds and molecules that promote the differentiation of oligodendrocyte progenitor cells and remyelination of the nervous system...
  8. doi Antibodies against CD20 (rituximab) for treating multiple sclerosis: US20100233121
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:111-4. 2011
    ..The application is in the field of medication and treatment for MS...
  9. ncbi Neurogenesis, NSCs, pathogenesis and therapies for Alzheimer's disease
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Front Biosci (Schol Ed) 3:178-90. 2011
    ..We will review and discuss the potential of adult NSCs for the treatment of AD and their contribution to the pathogenesis of the disease, as well as the development of novel drugs and therapies for treating AD...
  10. ncbi Neurogenic drugs and compounds to treat CNS diseases and disorders
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Cent Nerv Syst Agents Med Chem 11:35-7. 2011
    ....
  11. doi Chimeric proteins comprising the constant region of immunoglobulins for treating hemophilia B (WO2005001025)
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:967-70. 2011
    ..The application claims the methods of making recombinant chimeric proteins comprising of one biologically active molecule fused to the Fc region of the heavy chain(s) of immunoglobulins and their use for therapy...
  12. doi Modulation of GDP-fucose level for generating proteins with reduced rate of fucosylation (WO2010141855)
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:1497-9. 2011
    ..The application (WO2010141855) is in the field of glycobiology, and involves the control of the rate of fucosylation of proteins by exogenous factors...
  13. doi Parthenogenetically activated human oocytes and parthenogenetic embryonic stem cells: US20100233143
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin, Ireland
    Expert Opin Ther Pat 21:1281-3. 2011
    ..The application (US20100233143) is in the field of embryonic stems cells (ESCs) and the generation of ESCs from parthenogenetically activated human oocytes...
  14. doi Cell lines expressing mutant FX proteins to generate proteins with reduced rate of fucosylation: WO2010/141478
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:1143-6. 2011
    ..The application (WO 2010/141478) is in the field of glycobiology and deals with the synthesis of recombinant proteins with a reduced rate of fucosylation...
  15. doi Transplantation of two populations of stem cells to improve engraftment: WO2008060932
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 20:1259-63. 2010
    ..The application is in the field of haematopoietic stem cells (HSCs) and cellular therapy...
  16. doi Ex vivo fucosylation of stem cells to improve engraftment: WO2004094619
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin, Ireland
    Expert Opin Ther Pat 20:1265-9. 2010
    ..The application is in the field of haematopoietic stem cell (HSC) and umbilical cord blood (CB) transplantation...
  17. doi Very small embryonic-like stem cells for regenerative medicine: WO2010039241
    Philippe Taupin
    Dublin City University, Glasnevin, Dublin, Ireland
    Expert Opin Ther Pat 20:1103-6. 2010
    ..The application is in the field of stem cells and regenerative medicine...
  18. doi A simple and direct pre-embedding technique for ultrastructure of scarce biological specimens
    P Taupin
    Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology and Dublin City University, Dublin 9, Glasnevin, Ireland
    Biotech Histochem 83:253-7. 2008
    ..The ability to pre-embed scarce biological specimens efficiently and reproducibly provides a valuable way to study and characterize cytological tissues such as biopsies or cystic and amniotic fluid cells...
  19. doi Adult neural stem cells for the treatment of neuroinflammation. Fondazione Centro San Raffaele del Monte Tabor: WO2007015173
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:373-6. 2009
    ..The application is in the field of stem cells and their therapeutic application for the treatment of inflammation...
  20. doi Human neural progenitor and stem cells: US20080107633A1
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:377-80. 2009
    ..The application is in the field of neural stem cells (NSCs) and cellular therapy...
  21. doi Cryopreservation of early postmitotic neuronal cells in culture
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:265-8. 2009
    ..The application is in the field of embryonic stem cells (ESCs) and the cryopreservation of neuronal cells in culture...
  22. doi Fourteen compounds and their derivatives for the treatment of diseases and injuries characterized by reduced neurogenesis and neurodegeneration. Neuronascent, Inc.: WO2007035722
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:541-7. 2009
    ....
  23. doi Adult periodontal-derived neural progenitor and stem cells. Institut fur Molekulare Diagnostik und Innovative Therapie: WO2008031451
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:715-9. 2009
    ..Periodontal tissue can be harvested with minimal invasive procedures from the patient himself, providing a promising source of tissue for NSC-based therapy and autologous transplantation...
  24. doi Nootropic agents stimulate neurogenesis. Brain Cells, Inc.: WO2007104035
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:727-30. 2009
    ..The application claims the use of nootropic agents for their neurogenic activity and for the treatment of neurological diseases, disorders and injuries, by stimulating or increasing the generation of neuronal cells in the adult brain...
  25. ncbi Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promises
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Curr Alzheimer Res 6:461-70. 2009
    ..Limitations in protocols to establish homogeneous populations of neural progenitor and stem cells and niches for neurogenesis need to be resolved and unlocked, for the full potential of adult NSCs to be realized for therapy...
  26. ncbi A dual activity of ROS and oxidative stress on adult neurogenesis and Alzheimer's disease
    Philippe Taupin
    Dublin City University, Glasnevin, Ireland
    Cent Nerv Syst Agents Med Chem 10:16-21. 2010
    ..Antioxidant may be used to reduce the deleterious activity of ROS, particularly on newly generated neuronal cells of the adult brain, potentially delaying the development of AD and promoting the regenerative capacity of the adult brain...
  27. pmc Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells
    Philippe Taupin
    Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology, Glasnevin Dublin 9
    Int J Med Sci 5:127-32. 2008
    ..We will discuss the role and contribution of neuroinflammation and adult neurogenesis to neurological diseases and disorders, and for the therapeutic potential of adult NSCs...