Philippe Taupin

Summary

Affiliation: Dublin City University
Country: Ireland

Publications

  1. doi Adult periodontal-derived neural progenitor and stem cells. Institut fur Molekulare Diagnostik und Innovative Therapie: WO2008031451
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:715-9. 2009
  2. doi Nootropic agents stimulate neurogenesis. Brain Cells, Inc.: WO2007104035
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:727-30. 2009
  3. pmc Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells
    Philippe Taupin
    Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology, Glasnevin Dublin 9
    Int J Med Sci 5:127-32. 2008
  4. ncbi Neurogenic drugs and compounds to treat CNS diseases and disorders
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Cent Nerv Syst Agents Med Chem 11:35-7. 2011
  5. doi Adult neural stem cells for the treatment of neuroinflammation. Fondazione Centro San Raffaele del Monte Tabor: WO2007015173
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:373-6. 2009
  6. doi Human neural progenitor and stem cells: US20080107633A1
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:377-80. 2009
  7. doi Cryopreservation of early postmitotic neuronal cells in culture
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:265-8. 2009
  8. doi Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:523-7. 2009
  9. doi Fourteen compounds and their derivatives for the treatment of diseases and injuries characterized by reduced neurogenesis and neurodegeneration. Neuronascent, Inc.: WO2007035722
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:541-7. 2009
  10. ncbi Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promises
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Curr Alzheimer Res 6:461-70. 2009

Collaborators

Detail Information

Publications39

  1. doi Adult periodontal-derived neural progenitor and stem cells. Institut fur Molekulare Diagnostik und Innovative Therapie: WO2008031451
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:715-9. 2009
    ..Periodontal tissue can be harvested with minimal invasive procedures from the patient himself, providing a promising source of tissue for NSC-based therapy and autologous transplantation...
  2. doi Nootropic agents stimulate neurogenesis. Brain Cells, Inc.: WO2007104035
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:727-30. 2009
    ..The application claims the use of nootropic agents for their neurogenic activity and for the treatment of neurological diseases, disorders and injuries, by stimulating or increasing the generation of neuronal cells in the adult brain...
  3. pmc Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells
    Philippe Taupin
    Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology, Glasnevin Dublin 9
    Int J Med Sci 5:127-32. 2008
    ..We will discuss the role and contribution of neuroinflammation and adult neurogenesis to neurological diseases and disorders, and for the therapeutic potential of adult NSCs...
  4. ncbi Neurogenic drugs and compounds to treat CNS diseases and disorders
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Cent Nerv Syst Agents Med Chem 11:35-7. 2011
    ....
  5. doi Adult neural stem cells for the treatment of neuroinflammation. Fondazione Centro San Raffaele del Monte Tabor: WO2007015173
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:373-6. 2009
    ..The application is in the field of stem cells and their therapeutic application for the treatment of inflammation...
  6. doi Human neural progenitor and stem cells: US20080107633A1
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:377-80. 2009
    ..The application is in the field of neural stem cells (NSCs) and cellular therapy...
  7. doi Cryopreservation of early postmitotic neuronal cells in culture
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:265-8. 2009
    ..The application is in the field of embryonic stem cells (ESCs) and the cryopreservation of neuronal cells in culture...
  8. doi Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:523-7. 2009
    ....
  9. doi Fourteen compounds and their derivatives for the treatment of diseases and injuries characterized by reduced neurogenesis and neurodegeneration. Neuronascent, Inc.: WO2007035722
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 19:541-7. 2009
    ....
  10. ncbi Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promises
    Philippe Taupin
    School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
    Curr Alzheimer Res 6:461-70. 2009
    ..Limitations in protocols to establish homogeneous populations of neural progenitor and stem cells and niches for neurogenesis need to be resolved and unlocked, for the full potential of adult NSCs to be realized for therapy...
  11. ncbi A dual activity of ROS and oxidative stress on adult neurogenesis and Alzheimer's disease
    Philippe Taupin
    Dublin City University, Glasnevin, Ireland
    Cent Nerv Syst Agents Med Chem 10:16-21. 2010
    ..Antioxidant may be used to reduce the deleterious activity of ROS, particularly on newly generated neuronal cells of the adult brain, potentially delaying the development of AD and promoting the regenerative capacity of the adult brain...
  12. doi Very small embryonic-like stem cells for regenerative medicine: WO2010039241
    Philippe Taupin
    Dublin City University, Glasnevin, Dublin, Ireland
    Expert Opin Ther Pat 20:1103-6. 2010
    ..The application is in the field of stem cells and regenerative medicine...
  13. doi Ex vivo fucosylation of stem cells to improve engraftment: WO2004094619
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin, Ireland
    Expert Opin Ther Pat 20:1265-9. 2010
    ..The application is in the field of haematopoietic stem cell (HSC) and umbilical cord blood (CB) transplantation...
  14. doi Transplantation of two populations of stem cells to improve engraftment: WO2008060932
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 20:1259-63. 2010
    ..The application is in the field of haematopoietic stem cells (HSCs) and cellular therapy...
  15. ncbi Neurogenic drugs and compounds
    Philippe Taupin
    School of Biotechnology, Dublin City University, Dublin, Ireland
    Recent Pat CNS Drug Discov 5:253-7. 2010
    ..Here, we reviewed and discussed recent patents on neurogenic drugs and compounds, particularly nootropic agents and apigenin and related compounds...
  16. doi Thirteen compounds promoting oligodendrocyte progenitor cell differentiation and remyelination for treating multiple sclerosis: WO2010054307
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 20:1767-73. 2010
    ..Objective: It aims at identifying and characterizing compounds and molecules that promote the differentiation of oligodendrocyte progenitor cells and remyelination of the nervous system...
  17. doi Antibodies against CD20 (rituximab) for treating multiple sclerosis: US20100233121
    Philippe Taupin
    Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
    Expert Opin Ther Pat 21:111-4. 2011
    ..The application is in the field of medication and treatment for MS...
  18. ncbi Therapeutic potential of adult neural stem cells
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Recent Pat CNS Drug Discov 1:299-303. 2006
    ..In this manuscript, we will review the recent developments in adult neurogenesis and NSCs, and patent applications filed in relation to discoveries made in this new field of research...
  19. ncbi Stem cells engineering for cell-based therapy
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    J Neural Eng 4:R59-63. 2007
    ..In this review, I will review, in two examples, how investigators are applying cell engineering to stem cell biology to circumvent stem cells' ethical and political constraints and bolster stem cell research and therapy...
  20. ncbi Adult neurogenesis and neuroplasticity
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Restor Neurol Neurosci 24:9-15. 2006
    ..Thus, injury-induced neurogenesis may contribute to the recovery and plasticity of the CNS...
  21. ncbi Stroke-induced neurogenesis: physiopathology and mechanisms
    Philippe Taupin
    National Neuroscience Institute, Singapore, National University of Singapore, Nanyang Technological University, Singapore
    Curr Neurovasc Res 3:67-72. 2006
    ..In this manuscript, we will review the studies on adult neurogenesis in cerebral strokes, discuss the contribution of adult neurogenesis to the physiopathology of strokes, and its underlying mechanisms...
  22. ncbi Consideration of adult neurogenesis from basic science to therapy
    Philippe Taupin
    Med Sci Monit 11:LE16-17. 2005
  23. ncbi [Neurogenesis in the pathologies of the nervous system]
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, National University of Singapore, Nanyang Technological University, 308433 Singapore
    Med Sci (Paris) 21:711-4. 2005
    ..In this manuscript, we will review the studies on neurogenesis in the pathologies of the nervous system...
  24. ncbi Adult neurogenesis in the mammalian central nervous system: functionality and potential clinical interest
    Philippe Taupin
    National Neuroscience Institute, Singapore, Singapore
    Med Sci Monit 11:RA247-252. 2005
    ..Neural stem cells also hold the promise to cure a broad range of neurological diseases and injuries. Cell therapeutic interventions may involve both cell transplantation and the stimulation of endogenous neural progenitor cells...
  25. ncbi Microfabricated platform for studying stem cell fates
    Vicki I Chin
    Department of Bioengineering, 9500 Gilman Dr MC, University of California, San Diego, La Jolla, California 92093 0412, USA
    Biotechnol Bioeng 88:399-415. 2004
    ....
  26. ncbi [Control of maintenance of neural stem cells in mammals]
    Philippe Taupin
    Med Sci (Paris) 20:748-9. 2004
  27. ncbi Expression and function of orphan nuclear receptor TLX in adult neural stem cells
    Yanhong Shi
    Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nature 427:78-83. 2004
    ..TLX can silence glia-specific expression of the astrocyte marker GFAP in neural stem cells, suggesting that transcriptional repression may be crucial in maintaining the undifferentiated state of these cells...
  28. ncbi Derivation of embryonic stem cells for cellular therapy: challenges and new strategies
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Med Sci Monit 12:RA75-8. 2006
    ..In this manuscript, we will review and discuss these developments that may unlock ES cell research and therapy...
  29. ncbi HuCNS-SC (StemCells)
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, Singapore
    Curr Opin Mol Ther 8:156-63. 2006
    ..A phase I trial of HuCNS-SC for infantile and late-infantile NCL has been initiated, following the March 2006 U.S. Food and Drug Administration approval of StemCells' investigational new drug application...
  30. ncbi [Derivation of embryonic stem cells]
    Philippe Taupin
    Med Sci (Paris) 22:478-80. 2006
  31. ncbi Adult neural stem cells, neurogenic niches, and cellular therapy
    Philippe Taupin
    National Neuroscience Institute, Singapore
    Stem Cell Rev 2:213-9. 2006
    ..Hence, neurogenic niches may not only hold the key to our understanding of neurogenesis in the adult brain, but also of the developmental potential of adult NSCs, and their potential for cellular therapy...
  32. doi Adult neurogenesis pharmacology in neurological diseases and disorders
    Philippe Taupin
    National Neuroscience Institute National University of Singapore Nanyang Technological University, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore
    Expert Rev Neurother 8:311-20. 2008
    ..This shows that adult neurogenesis is not only important for our understanding of development and therapy, but also for the physiopathology of the CNS and its pharmacology...
  33. ncbi Alzheimer's disease, aneuploidy and neurogenesis
    Philippe Taupin
    Med Sci Monit 14:LE6-6. 2008
  34. ncbi Protocols for studying adult neurogenesis: insights and recent developments
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Regen Med 2:51-62. 2007
    ..I will review these techniques, and discuss their implications for the field of adult neurogenesis...
  35. ncbi Autologous transplantation in the central nervous system
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore and Nanyang Technological University, Singapore
    Indian J Med Res 124:613-8. 2006
    ....
  36. ncbi Neural progenitor and stem cells in the adult central nervous system
    Philippe Taupin
    National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore
    Ann Acad Med Singapore 35:814-20. 2006
    ..We will discuss their contribution and significance to CNS pathophysiology, and for cellular therapy...
  37. ncbi Neurogenesis in the adult central nervous system
    Philippe Taupin
    National Neuroscience Institute, Singapore, 11 Jalan Tan Tock Seng, Singapore 308433
    C R Biol 329:465-75. 2006
    ..Thus, not only neurogenesis contributes to reshaping the adult brain, it will ultimately lead us to redefine our knowledge and understanding of the nervous system...
  38. ncbi The therapeutic potential of adult neural stem cells
    Philippe Taupin
    National Neuroscience Institute, National University of Singapore, 11 Jalan Tan Tock Seng, 308433 Singapore
    Curr Opin Mol Ther 8:225-31. 2006
    ....
  39. ncbi Adult neurogenesis and neural stem cells of the central nervous system in mammals
    Philippe Taupin
    Laboratory of Genetics, The Salk Institute, La Jolla, California 92037 1099, USA
    J Neurosci Res 69:745-9. 2002