Aidan Coffey

Summary

Affiliation: Cork Institute of Technology
Country: Ireland

Publications

  1. ncbi Genome of a virulent bacteriophage Lb338-1 that lyses the probiotic Lactobacillus paracasei cheese strain
    Debebe Alemayehu
    Biotechnology Department, Moorepark Food Research Centre, Teagasc Moorepark, Cork, Ireland
    Gene 448:29-39. 2009
  2. ncbi Isolation and detection of Mycobacterium avium subsp. paratuberculosis (MAP) from cattle in Ireland using both traditional culture and molecular based methods
    Pierre E Douarre
    Cork Institute of Technology, Bishopstown, Cork, Ireland
    Gut Pathog 2:11. 2010
  3. ncbi Bacteriophage-resistance systems in dairy starter strains: molecular analysis to application
    Aidan Coffey
    Department of Biological Sciences, Cork Institute of Technology, Rossa Avenue, Cork, Ireland
    Antonie Van Leeuwenhoek 82:303-21. 2002
  4. ncbi Genome sequence of the phage clP1, which infects the beer spoilage bacterium Pediococcus damnosus
    David Kelly
    Department of Biological Sciences, Cork Institute of Technology, Co Cork, Ireland
    Gene 504:53-63. 2012
  5. ncbi Gene encoded antimicrobial peptides, a template for the design of novel anti-mycobacterial drugs
    James Carroll
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 1:408-12. 2010
  6. ncbi Ecofriendly control of potato late blight causative agent and the potential role of lactic acid bacteria: a review
    Claudia Axel
    School of Food and Nutritional Sciences, University College Cork, Western Road, Cork, Ireland
    Appl Microbiol Biotechnol 96:37-48. 2012
  7. ncbi Rapid identification, by use of the LTQ Orbitrap hybrid FT mass spectrometer, of antifungal compounds produced by lactic acid bacteria
    Brid Brosnan
    Team Elucidate, Department of Chemistry, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Anal Bioanal Chem 403:2983-95. 2012
  8. ncbi The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice
    Mark Fenton
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 1:404-7. 2010
  9. ncbi Comparative modelling of LysB from the mycobacterial bacteriophage Ardmore
    Marine Henry
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 2:88-95. 2011
  10. ncbi Recombinant bacteriophage lysins as antibacterials
    Mark Fenton
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Bioeng Bugs 1:9-16. 2010

Collaborators

Detail Information

Publications28

  1. ncbi Genome of a virulent bacteriophage Lb338-1 that lyses the probiotic Lactobacillus paracasei cheese strain
    Debebe Alemayehu
    Biotechnology Department, Moorepark Food Research Centre, Teagasc Moorepark, Cork, Ireland
    Gene 448:29-39. 2009
    ..Future studies will determine if the presence of bacteriophage phiLb338-1 or others in the human or animal gut plays an antagonistic role against the probiotic effect of beneficial bacteria...
  2. ncbi Isolation and detection of Mycobacterium avium subsp. paratuberculosis (MAP) from cattle in Ireland using both traditional culture and molecular based methods
    Pierre E Douarre
    Cork Institute of Technology, Bishopstown, Cork, Ireland
    Gut Pathog 2:11. 2010
    ..Faecal samples (290) were collected and screened for MAP by a conventional culture method and two PCR assays. In order to further evaluate the usefulness of molecular testing, a nested PCR was also assessed...
  3. ncbi Bacteriophage-resistance systems in dairy starter strains: molecular analysis to application
    Aidan Coffey
    Department of Biological Sciences, Cork Institute of Technology, Rossa Avenue, Cork, Ireland
    Antonie Van Leeuwenhoek 82:303-21. 2002
    ..This paper highlights the recent findings and developments that have been described in the literature that will have an impact on improvement of the phage-resistance of starter cultures...
  4. ncbi Genome sequence of the phage clP1, which infects the beer spoilage bacterium Pediococcus damnosus
    David Kelly
    Department of Biological Sciences, Cork Institute of Technology, Co Cork, Ireland
    Gene 504:53-63. 2012
    ..To our knowledge, this study represents the first reported P. damnosus phage genome sequence...
  5. ncbi Gene encoded antimicrobial peptides, a template for the design of novel anti-mycobacterial drugs
    James Carroll
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 1:408-12. 2010
    ..This is the first report to demonstrate an enhancement of efficacy by any bioengineered bacteriocin against mycobacteria...
  6. ncbi Ecofriendly control of potato late blight causative agent and the potential role of lactic acid bacteria: a review
    Claudia Axel
    School of Food and Nutritional Sciences, University College Cork, Western Road, Cork, Ireland
    Appl Microbiol Biotechnol 96:37-48. 2012
    ..This review describes the present situation of late blight disease and summarises current literature regarding the biocontrol of the phytopathogen P. infestans using antagonistic microorganisms...
  7. ncbi Rapid identification, by use of the LTQ Orbitrap hybrid FT mass spectrometer, of antifungal compounds produced by lactic acid bacteria
    Brid Brosnan
    Team Elucidate, Department of Chemistry, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Anal Bioanal Chem 403:2983-95. 2012
    ..This method allows comprehensive profiling and comparison of different LAB strains and is also capable of the identification of additional compounds produced by these bacteria...
  8. ncbi The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice
    Mark Fenton
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 1:404-7. 2010
    ..aureus. In the current study, the IVIS imaging system was used to demonstrate the effective elimination of a lux labeled S. aureus from the nares of BALB/c mice...
  9. ncbi Comparative modelling of LysB from the mycobacterial bacteriophage Ardmore
    Marine Henry
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 2:88-95. 2011
    ..This study presents an in silico 3D predictive model of Ardmore lysin and confirms the high diversity of mycobacteriophages LysB proteins both at the sequence (2D) and structural (predicted 3D) levels...
  10. ncbi Recombinant bacteriophage lysins as antibacterials
    Mark Fenton
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Bioeng Bugs 1:9-16. 2010
    ..This review discusses the extensive research on recombinant bacteriophage lysins in the context of antibacterials, and looks forward to future development and potential...
  11. ncbi Bacteriophage-Derived Peptidase CHAP(K) Eliminates and Prevents Staphylococcal Biofilms
    Mark Fenton
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Int J Microbiol 2013:625341. 2013
    ..Our data demonstrates the potential of CHAP(K) as a biocidal agent for prevention and treatment of biofilm-associated staphylococcal infections or as a decontaminating agent in the food and healthcare sectors...
  12. ncbi High-resolution melting analysis for rapid detection of linezolid resistance (mediated by G2576T mutation) in Staphylococcus epidermidis
    Emma M Gabriel
    Cork Institute of Technology, Cork, Ireland
    J Microbiol Methods 90:134-6. 2012
    ..This rapid method demonstrated 100% correlation with the previously established NheI restriction digest assay...
  13. ncbi Cloning and expression of a mureinolytic enzyme from the mycobacteriophage TM4
    Marine Henry
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    FEMS Microbiol Lett 311:126-32. 2010
    ..Evidence of peptidoglycan-degrading activity was observed initially by a chloroform assay and later by conventional zymogram analysis...
  14. ncbi High resolution melting PCR to differentiate Mycobacterium avium subsp. paratuberculosis"cattle type" and "sheep type"
    Pierre E Douarre
    Cork Institute of Technology, Cork, Ireland
    J Microbiol Methods 88:172-4. 2012
    ..paratuberculosis (cattle and sheep) based on the polymorphic variation of a previously described tandem repeat. This modern genotyping technique has several advantages over alternative methods, including cost, ease of use and rapidity...
  15. ncbi Lysins to kill - A tale of viral weapons of mass destruction
    Jim O' Mahony
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 2:306-8. 2011
    ....
  16. ncbi Development of a broad-host-range phage cocktail for biocontrol
    David Kelly
    Department of Biological Sciences, Cork Institute of Technology, Bishoptown, Cork, Ireland
    Bioeng Bugs 2:31-7. 2011
    ..2% of the entire staphylococcal bank). In conclusion, phage resistant systems affecting phage K are common in Staph. aureus but it is possible to significantly broaden the host-range of this phage for biocontrol applications...
  17. ncbi In silico analysis of Ardmore, a novel mycobacteriophage isolated from soil
    Marine Henry
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Ireland
    Gene 453:9-23. 2010
    ..A predicted beta-lactamase gene was detected in the sequence, and an unusual +1 frameshift event for the translation of tail genes was also observed...
  18. ncbi Antistaphylococcal activity of novel salicylanilide derivatives
    Annmarie Mollaghan
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Curr Drug Discov Technol 9:39-47. 2012
    ..5 μg ml(-1) was achievable. In this case, the dual presence of a trifluoromethyl group and an acetylated phenolic hydroxyl to the salicylanilide core structure led to greatly enhanced activity...
  19. ncbi Phage and their lysins as biocontrol agents for food safety applications
    Brid Coffey
    Teagasc, Biotechnology Center, Moorepark Food Research Center, Fermoy, Cork, Ireland
    Annu Rev Food Sci Technol 1:449-68. 2010
    ..The purpose of this review is to highlight the recent developments in the use of phages and their lysins for biocontrol and to address their potential future applications...
  20. ncbi Effects of cereal β-glucans and enzyme inclusion on the porcine gastrointestinal tract microbiota
    Padraigin Murphy
    Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland
    Anaerobe 18:557-65. 2012
    ..Overall both O diets had a more positive influence on the counts of the beneficial microorganisms and richness of the Lactobacillus population in the porcine GIT...
  21. ncbi "Green preservatives": combating fungi in the food and feed industry by applying antifungal lactic acid bacteria
    Agata M Pawlowska
    School of Food and Nutritional Sciences, University College Cork, Cork, Ireland
    Adv Food Nutr Res 66:217-38. 2012
    ..The attention points out the several industrial patents concerning the use of antifungal LAB as biocontrol agent against spoilage organisms in different fermented foods and feeds...
  22. ncbi Antifungal activity of Lactobacillus against Microsporum canis, Microsporum gypseum and Epidermophyton floccosum
    Jiahui Guo
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Bioeng Bugs 3:104-13. 2012
    ..reuteri ee1p strain was compared with both a multianalyte chromatogram and individual spectra of standard anti-fungal compounds, which are known to be produced by lactic acid bacteria. Ten antifungal metabolites were detected...
  23. ncbi Influence of in-situ synthesized exopolysaccharides on the quality of gluten-free sorghum sourdough bread
    Sandra Galle
    School of Food and Nutritional Science, University College Cork, Cork, Ireland
    Int J Food Microbiol 155:105-12. 2012
    ..Results of this study demonstrated that EPS formed during sourdough fermentation can be successfully applied in gluten-free sorghum flours to improve their bread-making potentials...
  24. ncbi Bacteriophage and their lysins for elimination of infectious bacteria
    Sarah O'Flaherty
    Moorepark Food Research Centre, Teagasc, Fermoy Co, Cork, Ireland
    FEMS Microbiol Rev 33:801-19. 2009
    ..Such developments have prompted this review into the status of phage research as it pertains to the control of infectious bacteria...
  25. ncbi Comparison of the activities of the lantibiotics nisin and lacticin 3147 against clinically significant mycobacteria
    James Carroll
    Department of Biological Sciences, Cork Institute of Technology, Cork, Ireland
    Int J Antimicrob Agents 36:132-6. 2010
    ..kansasii and >60 mg/L for MAP and M. tuberculosis H37Ra. Thus, lacticin 3147 is a potent antimycobacterial peptide that shows superior activity compared with nisin at physiological pH...
  26. ncbi Genome analysis of the obligately lytic bacteriophage 4268 of Lactococcus lactis provides insight into its adaptable nature
    Maeve Trotter
    Department of Microbiology, University College Cork, Ireland
    Gene 366:189-99. 2006
    ..The comparative analysis also supported the classification of phage 4268 and other BK5-T-related phage as separate from the proposed P335 species of lactococcal phage...
  27. ncbi Insertional inactivation of determinants for Mg2+ and Co2+ transport as a tool for screening recombinant Lactococcus species clones
    Susan Mills
    Teagasc, Dairy Products Research Centre, Moorepark, Fermoy, County Cork, Ireland
    Appl Environ Microbiol 71:4897-901. 2005
    ..Since only 3 of 17 lactococcal starters naturally harbor corA, the system has potential as a screen for selecting recombinant lactococcal clones...
  28. ncbi Variable bacteriocin production in the commercial starter Lactococcus lactis DPC4275 is linked to the formation of the cointegrate plasmid pMRC02
    Maeve Trotter
    Department of Microbiology, University College Cork, Ireland
    Appl Environ Microbiol 70:34-42. 2004
    ..Such derivatives of commercial strains producing increased levels of bacteriocin could be exploited as protection cultures for food applications...