Research Topics
Genomes and Genes | Eoin O'BrienSummaryAffiliation: Beaumont Hospital Country: Ireland Publications
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Publications
Has conventional sphygmomanometry ended with the banning of mercury?Eoin O'Brien
Blood Pressure Unit and ADAPT Centre, Beaumont Hospital, Dublin 9, Ireland
Blood Press Monit 7:37-40. 2002....
Validation of the TONOPORT V ambulatory blood pressure monitor according to the European Society of Hypertension International Protocol for Validation of Blood Pressure Measuring Devices in AdultsEoin O'Brien
Blood Pressure Unit, Beaumont Hospital and Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland
Blood Press Monit 8:255-60. 2003....
Validation of the ROSSMAX blood pressure measuring monitor according to the European Society of Hypertension International Protocol for Validation of Blood Pressure Measuring Devices in AdultsEoin O'Brien
Blood Pressure Unit, Beaumont Hospital and Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland
Blood Press Monit 8:261-5. 2003....
Can improved software facilitate the wider use of ambulatory blood pressure measurement in clinical practice?Eoin O'Brien
Blood Pressure Unit and ADAPT Centre, Beaumont Hospital, Dublin 9, Ireland
Blood Press Monit 9:237-41. 2004..The technique must, therefore, be made available in primary care, but in doing so it must be recognized that unfamiliarity with the technique may lead to misinterpretation of data...
Practice guidelines of the European Society of Hypertension for clinic, ambulatory and self blood pressure measurementRoland Asmar
Beaumont Hospital and Department of Clinical Pharmacology, Royal College of Surgeons, Beaumont Road, Dublin 9, Ireland
J Hypertens 23:697-701. 2005
Aliskiren: a renin inhibitor offering a new approach for the treatment of hypertensionEoin O'Brien
The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Expert Opin Investig Drugs 15:1269-77. 2006..This review outlines the background evidence for aliskiren, the first orally active renin inhibitor...
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blockerEoin O'Brien
Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Hypertension 49:276-84. 2007....
The circadian nuances of hypertension: a reappraisal of 24-h ambulatory blood pressure measurement in clinical practiceE O'Brien
Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Ir J Med Sci 176:55-63; discussion 65-6. 2007..The purpose of this review is to examine critically the information that can be derived from the technique and to highlight the application of this evidence in clinical practice...
State-of-the-market from the dableducational.org websiteEoin O'Brien
Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland
Blood Press Monit 12:377-9. 2007..In addition, the website provides a library resource with over 450 papers, and a device equivalence procedure for manufacturers...
A new solar-powered blood pressure measuring device for low-resource settingsGianfranco Parati
Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
Hypertension 56:1047-53. 2010....
A website for blood pressure measuring devices: dableducational.comEoin O'Brien
Department of Clinical Pharmacology, Royal College of Surgeons in Ireland and Blood Pressure Unit and ADAPT Centre, Beaumont, Dublin
Blood Press Monit 8:177-80. 2003..The website is due to be launched shortly and this paper outlines the general principles that have governed its establishment and the facilities that it will provide...
Ambulatory blood pressure measurement as a predictor of outcome in an Irish population: methodology for ascertaining mortality outcomeEamon Dolan
Department of Clinical Pharmacology, Royal College of Surgeons in Ireland and ADAPT Centre, Beaumont Hospital, Dublin, Ireland
Blood Press Monit 8:143-5. 2003..The purpose of this study was to evaluate the predictive value of ABPM in a sample of 14 414 people referred for management of cardiovascular risk...
Validation up-dateE O'Brien
Blood Pressure Unit and ADAPT Centre, Beaumont Hospital, Dublin 9, Ireland
Blood Press Monit 6:275-80. 2001....
State of the market for devices for blood pressure measurementE O'Brien
Blood Pressure Unit, Beaumont Hospital, Dublin 9, Ireland
Blood Press Monit 6:281-6. 2001..In this paper the published evidence for independent validation is reviewed and it is recommended that such reviews should be undertaken regularly by international bodies, such as the European Society of Hypertension...
Task Force I: methodological aspects of blood pressure measurementE O'Brien
Blood Pressure Unit, Beaumont Hospital, Dublin, Ireland
Blood Press Monit 6:313-5. 2001....
Demise of the mercury sphygmomanometer and the dawning of a new era in blood pressure measurementEoin O'Brien
Blood Pressure Unit and ADAPT Centre, Beaumont Hospital, Dublin 9, Ireland
Blood Press Monit 8:19-21. 2003....
European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurementRoland Asmar
J Hypertens 21:821-48. 2003
What to do when faced with an unmeasurable ambulatory blood pressure?Eoin O'Brien
Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland
J Hypertens 29:451-3. 2011....
Ambulatory blood pressure measurement is indispensable to good clinical practiceEoin O'Brien
Blood Pressure Unit and ADAPT Centre, Beaumont Hospital, Dublin, Ireland
J Hypertens Suppl 21:S11-8. 2003..However, if ABPM is to be widely used in general practice, there is a need to establish appropriate educational processes and to improve the methods of presenting and analysing ABPM data...
Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskirenAlice Stanton
Blood Pressure Unit, Beaumont Hospital, Dublin, Ireland
Hypertension 42:1137-43. 2003..Whether renin inhibition results in protection from heart attack, stroke, and nephropathy, similar to angiotensin-converting enzyme inhibition and angiotensin receptor blockade, needs to be researched...
Confirmation that the renin gene distal enhancer polymorphism REN-5312C/T is associated with increased blood pressureCiara Vangjeli
Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Belfield, Dublin, Ireland
Circ Cardiovasc Genet 3:53-9. 2010..However, whether polymorphisms in these genes contribute to the cause of essential hypertension in humans is still a matter of debate...
Twenty-four-hour ambulatory blood pressure in community-dwelling elderly men and women, aged 60-102 yearsCianán O'Sullivan
The Blood Pressure Unit, Beaumont Hospital, Dublin, Ireland
J Hypertens 21:1641-7. 2003..To investigate ambulatory blood pressure in elderly people, including 'old elderly' subjects, aged over 80 years...
Superiority of ambulatory over clinic blood pressure measurement in predicting mortality: the Dublin outcome studyEamon Dolan
ADAPT Centre, Beaumont Hospital, Department of Clinical Pharmacology, Royal College of Surgeons, Dublin, Ireland
Hypertension 46:156-61. 2005..These results have 2 important clinical messages: ambulatory measurement of blood pressure is superior to clinic measurement in predicting cardiovascular mortality, and nighttime blood pressure is the most potent predictor of outcome...
Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome StudyEamon Dolan
The ADAPT Centre, Beaumont Hospital, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin, Ireland
Hypertension 47:365-70. 2006..89; P=0.47 versus 0.40). AASI is a novel measure of arterial stiffness, which can be readily determined from ambulatory blood pressure recordings and which independently predicts cardiovascular mortality, even in normotensive subjects...
Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in CaucasiansCiara Dolan
Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland
BMC Med Genet 6:41. 2005..We investigated whether common polymorphisms of the FMO3 gene confer an increased risk for elevated blood pressure and/or essential hypertension...
Hypertensive target-organ damage in the very elderlyCianán O'Sullivan
Blood Pressure Unit, Beaumont Hospital, Dublin, Ireland
Hypertension 42:130-5. 2003..In advanced old age, HT is associated with evidence of target-organ damage. ABPM can improve on CBPM in predicting very elderly subjects with HT target-organ damage...
The dabl Educational Trust device equivalence procedureNeil Atkins
dabl Educational Trust, Dublin, Ireland
Blood Press Monit 12:246-9. 2007..In this paper the procedure for manufacturers to declare the equivalence of a modified device with a device that has been validated earlier is described...
Short-term and long-term repeatability of the morning blood pressure in older patients with isolated systolic hypertensionBarbara Wizner
Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium
J Hypertens 26:1328-35. 2008..Using 24-h ambulatory blood pressure monitoring, we studied the repeatability of the morning blood pressure in older (> or =60 years) patients with isolated systolic hypertension...
Limitations of current validation protocols for home blood pressure monitors for individual patientsWilliam Gerin
The Zena and Michael A Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
Blood Press Monit 7:313-8. 2002..We assessed the adequacy of existing British Hypertension Society (BHS) and Association for the Advancement of Medical Instrumentation (AAMI) validation standards for automatic blood pressure monitoring devices...
