Mohammad R Zarrindast

Summary

Affiliation: Tehran University of Medical Sciences
Country: Iran

Publications

  1. ncbi Role of nitric oxide in systemic effect of theophylline on mouse body temperature
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 451:63-8. 2002
  2. ncbi Dorsal hippocampal muscarinic and nicotinic receptors are involved in mediating morphine reward
    Ameneh Rezayof
    Department of Biology, Faculty of Science, Tehran University, Tehran, Iran
    Behav Brain Res 166:281-90. 2006
  3. ncbi Repeated administration of dopaminergic agents in the nucleus accumbens and morphine-induced place preference
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Behav Brain Res 169:248-55. 2006
  4. ncbi Morphine-induced antinociception in the formalin test: sensitization and interactions with D1 and D2 dopamine receptors and nitric oxide agents
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 18:177-84. 2007
  5. ncbi Nitric oxide modulates state dependency induced by lithium in an inhibitory avoidance task in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Medical Sciences University of Tehran, Iran
    Behav Pharmacol 18:289-95. 2007
  6. doi The involvement of dorsal hippocampus in dextromethorphan-induced state-dependent learning in mice
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran School of Cognitive Sciences, Institute for Research in Fundamental Sciences IPM, Tehran, Iran Institute of Cognitive Science Studies ICSS, Tehran, Iran Electronic address
    Pharmacol Biochem Behav 116:90-5. 2014
  7. doi Role of the medial septum cholinoceptors in anxiogenic-like effects of nicotine
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran, Iran
    Physiol Behav 119:103-9. 2013
  8. doi Effects of dopamine receptor agonist and antagonists on cholestasis-induced anxiolytic-like behaviors in rats
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 702:25-31. 2013
  9. doi Evaluation of functional relationship between mouse hippocampal cholinergic and nitrergic systems in anxiogenic-like behavior
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 24:229-36. 2013
  10. doi Interaction between morphine and noradrenergic system of basolateral amygdala on anxiety and memory in the elevated plus-maze test based on a test-retest paradigm
    Farhad Valizadegan
    Faculty of Biological Sciences, Tarbiat Moallem Kharazmi University, Tehran, Iran
    Arch Iran Med 16:281-7. 2013

Collaborators

Detail Information

Publications125 found, 100 shown here

  1. ncbi Role of nitric oxide in systemic effect of theophylline on mouse body temperature
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 451:63-8. 2002
    ..Both L-NAME and L-NA by themselves reduced body temperature. It is concluded that nitric oxide (NO) may be involved in the effects of theophylline on body temperature in mice...
  2. ncbi Dorsal hippocampal muscarinic and nicotinic receptors are involved in mediating morphine reward
    Ameneh Rezayof
    Department of Biology, Faculty of Science, Tehran University, Tehran, Iran
    Behav Brain Res 166:281-90. 2006
    ..It may be concluded that the muscarinic and nicotinic receptors of the hippocampal CA1 regions play an important role in morphine reward...
  3. ncbi Repeated administration of dopaminergic agents in the nucleus accumbens and morphine-induced place preference
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Behav Brain Res 169:248-55. 2006
    ..It is concluded that repeated injections of dopamine receptors agents followed by 5 days free of the drugs in the NAc can affect morphine reward...
  4. ncbi Morphine-induced antinociception in the formalin test: sensitization and interactions with D1 and D2 dopamine receptors and nitric oxide agents
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 18:177-84. 2007
    ..It is concluded that D2 dopamine receptor and nitric oxide mechanisms may be involved at least partly in morphine-induced sensitization in the formalin test...
  5. ncbi Nitric oxide modulates state dependency induced by lithium in an inhibitory avoidance task in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Medical Sciences University of Tehran, Iran
    Behav Pharmacol 18:289-95. 2007
    ..The results suggest that NO may have a modulatory role on state-dependent retrieval of inhibitory avoidance memory induced by lithium...
  6. doi The involvement of dorsal hippocampus in dextromethorphan-induced state-dependent learning in mice
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran School of Cognitive Sciences, Institute for Research in Fundamental Sciences IPM, Tehran, Iran Institute of Cognitive Science Studies ICSS, Tehran, Iran Electronic address
    Pharmacol Biochem Behav 116:90-5. 2014
    ..Moreover, DM can induce state-dependent learning. Dorsal hippocampus appears to play an important role upon DM influence of learning and memory processes. ..
  7. doi Role of the medial septum cholinoceptors in anxiogenic-like effects of nicotine
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran, Iran
    Physiol Behav 119:103-9. 2013
    ..Our results suggested that, nicotine-induced anxiogenic-like behaviors may be mediated via the activation of cholinoceptors and possibly other receptor mechanism(s) in the medial septum...
  8. doi Effects of dopamine receptor agonist and antagonists on cholestasis-induced anxiolytic-like behaviors in rats
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 702:25-31. 2013
    ..These findings suggested that the dopaminergic system may potentially be involved in the modulation of cholestasis-induced anxiolytic-like behaviors in rats...
  9. doi Evaluation of functional relationship between mouse hippocampal cholinergic and nitrergic systems in anxiogenic-like behavior
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 24:229-36. 2013
    ..Thus, both L-NAME and L-arginine showed anxiogenic-like effects, but the effects of mecamylamine were too small to support a functional relationship between the hippocampal cholinergic and nitrergic systems...
  10. doi Interaction between morphine and noradrenergic system of basolateral amygdala on anxiety and memory in the elevated plus-maze test based on a test-retest paradigm
    Farhad Valizadegan
    Faculty of Biological Sciences, Tarbiat Moallem Kharazmi University, Tehran, Iran
    Arch Iran Med 16:281-7. 2013
    ..The amygdala is the key brain structure for anxiety and emotional memory storage. We examined the involvement of β-adrenoreceptors in the basolateral amygdala (BLA) and their interaction with morphine in modulating these behaviors...
  11. doi β-Adrenoceptors in the dorsal hippocampus are involved in ethanol-induced state-dependent retrieval in mice
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Neurobiol Learn Mem 100:12-7. 2013
    ..In conclusion, the results support the existence of a functional involvement of β-adrenoceptors in the DH in ethanol-induced state-dependent retrieval...
  12. doi Modulation of ventral tegmental area dopamine receptors inhibit nicotine-induced anxiogenic-like behavior in the central amygdala
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Prog Neuropsychopharmacol Biol Psychiatry 41:11-7. 2013
    ..An understanding of these cellular processes will be crucial for the development of new intervention to combat nicotine effect...
  13. doi Involvement of rat dopaminergic system of nucleus accumbens in nicotine-induced anxiogenic-like behaviors
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
    Brain Res 1460:25-32. 2012
    ..These findings may suggest the involvement of dopamine transmission, through D₁ and D₂ receptors of NAc shell, in the anxiogenic-like effect of nicotine in the EPM task...
  14. doi Nicotine-induced anxiogenic-like behaviours of rats in the elevated plus-maze: possible role of NMDA receptors of the central amygdala
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies and Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Psychopharmacol 26:555-63. 2012
    ..1 μ g/rat) in the EPM. The results may support the possible involvement of glutamate transmission, through NMDA receptors of central amygdala in the anxiogenic-like effect of nicotine in the EPM task...
  15. doi Activation of dopamine D1 receptors in the medial septum improves scopolamine-induced amnesia in the dorsal hippocampus
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Brain Res 229:68-73. 2012
    ..These results suggest that dopamine D1 receptors in the MS via projection neurons to the hippocampus affect impairment of memory consolidation induced by intra-CA injections of scopolamine...
  16. ncbi Adrenoceptor mechanisms underlying imipramine-induced memory deficits in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Psychopharmacol 17:83-8. 2003
    ..Yohimbine pretreatment attenuated the effect of clonidine. It is concluded that alpha2-adrenoceptor mechanism(s) may be involved in imipramine-induced impairment of memory...
  17. ncbi GABAergic system and imipramine-induced impairment of memory retention in rats
    M R Zarrindast
    Department of Pharmacology, Tehran University of Medical Science and Department of Biology, Shaheed Beheshti University, Tehran, Iran
    Eur Neuropsychopharmacol 14:59-64. 2004
    ..It is concluded that the GABA(B) receptor mechanism is involved in memory impairment induced by imipramine...
  18. ncbi Neurotransmitters and cognition
    Mohammad R Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    EXS 98:5-39. 2006
  19. ncbi Influence of ATP-sensitive potassium channels on lithium state-dependent memory of passive avoidance in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 550:107-11. 2006
    ..Therefore, ATP-sensitive potassium channels may have a modulatory influence on lithium response...
  20. ncbi Influence of ATP-dependent K+ channels on nicotine-induced inhibition of withdrawal in morphine-dependent mice
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 552:90-8. 2006
    ..According to these results the interaction of nicotine with the K(ATP) channel opener and blocker in morphine physical withdrawal signs could be explained by direct and indirect effects of nicotine on membrane potassium currents...
  21. ncbi The effects of histaminergic agents in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacol Biochem Behav 85:500-6. 2006
    ..The results may indicate an anxiogenic effect for the antagonist. Our results showed that histamine may modulate anxiety via H1 and H2 receptors in the CA1 region of hippocampus of the rat...
  22. ncbi Repeated pre-exposure to morphine into the ventral pallidum enhances morphine-induced place preference: involvement of dopaminergic and opioidergic mechanisms
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Brain Res 181:35-41. 2007
    ..It is concluded that repeated intra-VP injections of morphine induces behavioral sensitization, which may be due to the opioidrgic and/or dopaminergic mechanism(s)...
  23. ncbi NMDA receptors of dorsal hippocampus are involved in the acquisition, but not in the expression of morphine-induced place preference
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 568:192-8. 2007
    ..None of the drugs influenced locomotion. It is concluded that NMDA receptor of the CA1 region of hippocampus are involved in the acquisition but not expression of morphine-induced place preference...
  24. ncbi Morphine state-dependent learning sensitization and interaction with nitric oxide
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784 Tehran, Iran
    Pharmacology 78:66-71. 2006
    ..It is concluded that NO is involved in the morphine-induced sensitization...
  25. ncbi Influence of acute and sub-chronic nicotine pretreatment on morphine state-dependent learning
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Brain Res 173:268-73. 2006
    ..The results suggest that nicotine may induce sensitization which affects the impairment of memory formation via cholinergic but not dopaminergic systems...
  26. ncbi Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice
    M R Zarrindast
    Department of Pharmacology, Medical School, Tehran University of Medical Sciences, Iran
    Int J Neurosci 116:963-73. 2006
    ..The effect of muscimol was not altered by bicuculline pretreatment. It is concluded that both GABAA and GABAB receptor activation reduced Straub tail induced by morphine...
  27. ncbi Histaminergic receptors of medial septum and conditioned place preference: D1 dopamine receptor mechanism
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Brain Res 1109:108-16. 2006
    ..The results suggest that histaminergic receptors of the medial septum may be involved in CPP and thus it is postulated that dopamine D1 receptors may play an important role in this effect...
  28. ncbi Involvement of NMDA receptors in morphine state-dependent learning in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine Tehran University of Medical Sciences, Tehran, Iran
    Int J Neurosci 116:731-43. 2006
    ..5, 1, and 2 microg/mouse, i.c.v.) with morphine (5 mg/kg, s.c.) increased and decreased morphine state-dependent learning, respectively. The results suggest that NMDA receptors are involved in morphine state-dependent learning in mice...
  29. ncbi Influence of intracerebroventricular administration of dopaminergic drugs on morphine state-dependent memory in the step-down passive avoidance test
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Neurobiol Learn Mem 86:286-92. 2006
    ..In conclusion, the morphine-induced recovery of memory, on the test day, seems to be induced, at least in part, through dopamine receptors...
  30. ncbi Influence of morphine- or apomorphine-induced sensitization on histamine state-dependent learning in the step-down passive avoidance test
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Iran
    Behav Brain Res 171:50-5. 2006
    ..The results suggest that apomorphine or morphine sensitization affects the impairment of memory induced by histamine and thus it is postulated that opioid and dopamine receptors may play an important role in this effect...
  31. ncbi Morphine-induced sensitization in mice: changes in locomotor activity by prior scheduled exposure to GABAA receptor agents
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 18:303-10. 2007
    ..The magnitude of this response was, however, variable. The results indicate that GABAA receptors might be involved in the acquisition of morphine-induced sensitization...
  32. ncbi Involvement of glucose and ATP-sensitive potassium (K+) channels on morphine-induced conditioned place preference
    Mohammad R Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Medical Sciences, University of Tehran, Iran
    Eur J Pharmacol 573:133-8. 2007
    ..Drug injections had no effects on locomotor activity during the test sessions. It is concluded that glucose and the ATP-sensitive K+ channel may play an active role in morphine reward...
  33. doi Influence of three-day morphine-treatment upon impairment of memory consolidation induced by cannabinoid infused into the dorsal hippocampus in rats
    Mohammad Reza Zarrindast
    Department of Neuroscience, School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
    Neurosci Res 69:51-9. 2011
    ..The results have suggested that subchronic morphine treatment may cause mu-opioid and D(2) receptor sensitization, which in turn prevents impairment of memory consolidation induced by WIN55,212-2...
  34. doi Anxiolytic-like effect induced by the cannabinoid CB1 receptor agonist, arachydonilcyclopropylamide (ACPA), in the rat amygdala is mediated through the D1 and D2 dopaminergic systems
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Psychopharmacol 25:131-40. 2011
    ..5 µg/rat) decreased the anxiolytic-like effect of ACPA. It can be concluded that the dopaminergic system of the amygdala may be involved, at least partly, in the anxiolytic-like effects induced by ACPA in the rat amygdala...
  35. doi Nicotinic acetylcholine receptors of the dorsal hippocampus and the basolateral amygdala are involved in ethanol-induced conditioned place preference
    M R Zarrindast
    School of Advanced Medical Technologies and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Neuroscience 168:505-13. 2010
    ..It can be concluded that the activation of nicotinic acetylcholine receptors of the dorsal hippocampus and the basolateral amygdala can potentiate the ethanol response in the CPP paradigm...
  36. doi The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Advanced Medical Technologies and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Neurosci Lett 475:156-60. 2010
    ..1microg/rat) decreased nicotine's effect. The results may indicate a modulatory effect for the D(1) and D(2) dopamine receptors of VHC in the anxiogenic-like response induced by nicotine...
  37. doi Blockade of dorsal hippocampal dopamine receptors inhibits state-dependent learning induced by cannabinoid receptor agonist in mice
    Mohammad Reza Zarrindast
    School of Advanced Medical Technologies and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Neurosci Res 67:25-32. 2010
    ..2 and 0.3 microg/mouse) or sulpiride (0.125 microg/mouse) decreased memory retrieval. The results suggest that the dorsal hippocampal dopaminergic system participates in the modulation of WIN55,212-2-induced state-dependent learning...
  38. doi Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    J Psychopharmacol 24:881-9. 2010
    ..It can be concluded that the histamine system is involved in anxiety-like behavior, and repeated injections of morphine followed by five days free of the drugs interact with histamine receptor mechanism...
  39. doi Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacol Biochem Behav 94:387-96. 2010
    ..In conclusion, our results showed that there is a chance of partial interaction between the cannabinoidergic and the histaminergic systems of the dorsal hippocampus on anxiogenic/anxiolytic-like behaviors in hole-board test...
  40. doi Effect of intra-amygdala injection of nicotine and GABA receptor agents on anxiety-like behaviour in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacology 82:276-84. 2008
    ..25, 0.5 and 1 microg/rat) had no interaction on %OAT, %OAE and locomotor activity. It can be concluded that in the central amygdala, the GABAergic system is not involved in the anxiogenic response to nicotine...
  41. doi Cannabinoid CB1 receptors of the rat central amygdala mediate anxiety-like behavior: interaction with the opioid system
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 19:716-23. 2008
    ..In conclusion, the results may indicate an anxiolytic-like effect for cannabinoid CB1 receptors of the CeA and the existence of an interaction between the cannabinoid and the opioid systems in the modulation of anxiety...
  42. doi Repeated administrations of dopamine receptor agents affect lithium-induced state-dependent learning in mice
    Mr Zarrindast
    Department of Pharmacology, Tehran University of Medical Sciences, Tehran, Iran
    J Psychopharmacol 23:645-51. 2009
    ..3 and 1 microg/mouse) disrupted the state-dependent learning induced by lithium. These results suggest that state-dependent learning induced by lithium may be altered by repeated pretreatment of dopamine receptor agents...
  43. doi Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 583:108-14. 2008
    ..The results may indicate that the histaminergic system of lateral septum modulate anxiety-like behaviour through histamine H1 and H2 receptors...
  44. doi Possible involvement of mu-opioid receptors in effect of lithium on inhibitory avoidance response in mice
    M R Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Institute for Study Theoretical Physics and Mathematics, Tehran, Iran
    J Psychopharmacol 22:865-71. 2008
    ..c.v.) and lithium (2 microg/mouse, i.c.v.) on memory retrieval. The results suggest that the mu-opioid receptors in the central nervous system may be involved in the retrieval of lithium state-dependent learning...
  45. ncbi Inhibition of morphine-induced amnesia in morphine-sensitized mice: involvement of dorsal hippocampal GABAergic receptors
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Neuropharmacology 54:569-76. 2008
    ..The results suggest that morphine sensitization reverses the impairment of memory induced by morphine and that GABAergic receptors of the dorsal hippocampus may play an important role in this effect...
  46. ncbi Repeated administration of histamine improves memory retrieval of inhibitory avoidance by lithium in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacology 81:187-94. 2008
    ..p.) on memory retrieval. The results suggest that the repeated administration of histaminergic agents may induce a sensitization which affects the memory impairment induced by lithium...
  47. doi Involvement of the dopaminergic receptors of the rat basolateral amygdala in anxiolytic-like effects of the cholinergic system
    Mohammad Reza Zarrindast
    Department of Biology, North Branch, Azad University, Tehran, Iran
    Eur J Pharmacol 672:106-12. 2011
    ..Furthermore, dopaminergic system activation probably via dopamine D(1) and D(2) receptors is necessary for mediating anxiolytic-like effects of physostigmine...
  48. ncbi GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice
    M Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Science, P O Box 13145 784, Tehran, Iran
    Eur J Pharmacol 407:65-72. 2000
    ..It is concluded that a GABA receptor mechanism(s) may modulate the antidepressant-induced antinociception...
  49. ncbi Effects of alpha-adrenoceptor agonists and antagonists on histamine-induced impairment of memory retention of passive avoidance learning in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 454:193-8. 2002
    ..It is concluded that a histamine-induced impairment of memory retention through histamine H(1) receptors and an alpha(2)-adrenoceptor mechanism may be involved in the histamine response...
  50. ncbi Involvement of dopamine D1 receptors of the central amygdala on the acquisition and expression of morphine-induced place preference in rat
    Mohammad Reza Zarrindast
    Department of Pharmacology, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Brain Res 965:212-21. 2003
    ..The results indicate that the dopamine D1 receptors in the CeA may be involved in the acquisition and expression of morphine-induced place preference...
  51. ncbi Repeated administration of dopaminergic agents in the dorsal hippocampus and morphine-induced place preference
    M R Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 16:85-92. 2005
    ..It is concluded that repeated injections of DA receptor agents in the dorsal hippocampus, followed by 5 days free of the drugs, can affect morphine reward...
  52. ncbi The effect of electroconvulsive shock seizures on behaviour induced by dopaminergic agonists and on immobility in the Porsolt test
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Eur Neuropsychopharmacol 14:509-14. 2004
    ..It is concluded that ECS increases activity in the dopaminergic systems of the rat brain for at least 1-2 weeks post-seizure. The beneficial effects of electroconvulsive therapy (ECT) may relate to these dopaminergic alterations...
  53. ncbi Adenosine receptor agonists or antagonists alter antinociception, but did not show an interaction with imipramine-induced antinociception in the formalin test in mice
    Mohammad Reza Zarrindast
    Tehran University of Medical Sciences, School of Medicine, Department of Pharmacology, P O Box 13145 784, Tehran, Iran
    Eur Neuropsychopharmacol 13:165-72. 2003
    ..Theophylline reduced the response induced by imipramine. It is concluded that adenosine systems are not involved in imipramine responses in the formalin test...
  54. ncbi Influence of beta-adrenoceptor agonists and antagonists on baclofen-induced memory impairment in mice
    M R Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Science, Tehran, Iran National Centre for Drug Addiction Studies, Tehran, Iran
    Behav Pharmacol 15:293-7. 2004
    ..It is concluded that beta-adrenergic mechanisms may be involved in the modulation of memory via GABAB receptors...
  55. ncbi Imipramine-induced antinociception in the formalin test. Receptor mechanisms involved and effect of swim stress
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Science, Tehran, Iran
    Pharmacology 68:154-61. 2003
    ..The results indicate that the responses of swim stress and imipramine may be mediated by an opioid mechanism, but the combination of both drugs induced higher antinociceptive effects...
  56. ncbi Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Eur J Pharmacol 471:105-12. 2003
    ..It is concluded that the histamine H(2) receptor mechanism may be involved in the influence of histamine on the expression of naloxone-induced jumping in morphine-dependent mice...
  57. ncbi Influence of alpha-adrenoceptor agonists and antagonists on imipramine-induced hypothermia in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Science, Tehran, Iran
    Pharmacol Toxicol 93:48-53. 2003
    ..It is concluded that alpha2-adrenoceptor mechanism may be involved in the hypothermic effect of imipramine...
  58. ncbi Influence of central administration ATP-dependent K+ channel on morphine state-dependent memory of passive avoidance
    Mohammad R Zarrindast
    Department of Pharmacology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
    Eur J Pharmacol 487:143-8. 2004
    ..Diazoxide blocked the effects of glibenclamide on memory restoration. It is concluded that K(ATP) channel modulators may be involved, at least in part, in morphine state dependence through a cholinergic system mechanism...
  59. ncbi Effects of imipramine on the expression and development of morphine dependence in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Eur J Pharmacol 473:19-25. 2003
    ..It is concluded an alpha2-adrenoceptor mechanism may be involved in the influence of imipramine on the expression and development of naloxone-induced withdrawal signs in mice...
  60. ncbi Role of nitric oxide in the acquisition and expression of apomorphine- or morphine-induced locomotor sensitization
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Pharmacol 482:205-13. 2003
    ..The results indicate that NO may be involved in the acquisition and expression of apomorphine- or morphine-induced sensitization...
  61. ncbi Potentiation of imipramine-induced antinociception by nicotine in the formalin test
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784 Tehran, Iran
    Eur Neuropsychopharmacol 14:71-6. 2004
    ..25 mg/kg) altered the antinociception induced by imipramine. It is concluded that nicotinic receptor activation but not the cholinergic muscarinic mechanism is involved in the imipramine-induced antinociception...
  62. ncbi Influence of nitric oxide on morphine-induced conditioned place preference in the rat central amygdala
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 453:81-9. 2002
    ..It may be concluded that an increase in the NO levels in the central amygdala may have an effect on the acquisition and expression of morphine-induced conditioned place preference...
  63. ncbi Involvement of the ventral tegmental area (VTA) in morphine-induced memory retention in morphine-sensitized rats
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Behav Brain Res 163:100-6. 2005
    ..c.) or sulpiride (25, 50 and 100mg/kg, s.c.), during the sensitization. The results suggest that VTA has an important role in morphine-induced amnesia and morphine sensitization affects this process through opioid and dopamine receptors...
  64. ncbi The effects of simultaneous administration of alpha(2) -adrenergic agents with L-NAME or L-arginine on the development and expression of morphine dependence in mice
    M R Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Behav Pharmacol 13:117-25. 2002
    ..In conclusion, alpha(2)-adrenergic and NO pathways seem to be functionally linked in the modulation of opioid dependence...
  65. ncbi GABA mechanisms and antinociception in mice with ligated sciatic nerve
    M R Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacol Toxicol 89:79-84. 2001
    ....
  66. ncbi The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 16:643-9. 2005
    ..5 microl bilateral. The results suggest that histamine may modulate anxiety via H1 but not H2 receptors in the rat central amygdala...
  67. ncbi Nicotine potentiation of morphine-induced catalepsy in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Pharmacol Biochem Behav 72:197-202. 2002
    ..It was concluded that morphine catalepsy can be elicited by opioid and cholinergic receptors, and the potentiation of morphine induced by nicotine may also be mediated through cholinergic receptor mechanisms...
  68. ncbi Baclofen-impairment of memory retention in rats: possible interaction with adrenoceptor mechanism(s)
    M R Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Science, P O Box 13145 784, Tehran, Iran
    Eur J Pharmacol 411:283-8. 2001
    ..5--2 microg/rat) decreased memory retention. The combination of the two drugs showed an interaction. It may be concluded that an adrenoceptor mechanism may interact with the memory retention impairment induced by baclofen...
  69. ncbi Effect of the GABAergic system on memory formation and state-dependent learning induced by morphine in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology and Iranian National Center for Addiction Studies, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Pharmacology 76:93-100. 2006
    ..It is concluded that the GABA(A) receptor mechanisms may be involved in the memory formation and it is postulated that these receptors may play an important role in morphine state-dependent learning...
  70. ncbi Dopamine receptor mechanism(s) and morphine tolerance in mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    J Psychopharmacol 16:261-6. 2002
    ..It was concluded that D2 dopaminergic receptors may play a part in the expression and development of tolerance to the antinociceptive effect of morphine...
  71. ncbi The effects of dopamine receptor agents on naloxone-induced jumping behaviour in morphine-dependent mice
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 451:287-93. 2002
    ....
  72. ncbi Effects of histamine and opioid systems on memory retention of passive avoidance learning in rats
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Eur J Pharmacol 452:193-7. 2002
    ..The responses to pentazocine and naloxone also were decreased by histamine. It is concluded that the histaminergic system has an interaction with opioidergic system that is involved in the memory retention process...
  73. ncbi The role of alpha-adrenoceptors in the amnestic effect of intracerebroventricular dexamethasone
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Pharmacol Res 46:339-44. 2002
    ..These data suggest that dexamethasone may induce its amnestic effect through activation of alpha(2)-adrenoceptors, leading to decreased alpha(1)-adrenergic activity...
  74. ncbi Cross state-dependent retrieval between histamine and lithium
    Mohammad Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Physiol Behav 86:154-63. 2005
    ..In conclusion, histamine or lithium can induce state-dependent retrieval and a cross-StD exists between these drugs, which may be mediated through the inositol pathway...
  75. ncbi GABA(A) receptors of hippocampal CA1 regions are involved in the acquisition and expression of morphine-induced place preference
    Ameneh Rezayof
    School of Biology, University College of Science, University of Tehran, Tehran, Iran
    Eur Neuropsychopharmacol 17:24-31. 2007
    ..Our data indicated that the GABA(A) receptors of the hippocampal CA1 regions may play an important role in the acquisition and expression of morphine-induced place preference...
  76. ncbi Morphine-induced place preference: involvement of cholinergic receptors of the ventral tegmental area
    Ameneh Rezayof
    School of Biology, University College of Science, University of Tehran, Tehran, Iran
    Eur J Pharmacol 562:92-102. 2007
    ..We conclude that muscarinic and nicotinic acetylcholine receptors in the ventral tegmental area may critically mediate the rewarding effects of morphine...
  77. doi Modulation of morphine state-dependent learning by muscarinic cholinergic receptors of the ventral tegmental area
    Niloufar Darbandi
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran
    Physiol Behav 94:604-10. 2008
    ..It may be concluded that the muscarinic acetylcholine receptors of the VTA play an important role in morphine-induced recovery of memory, on the test day...
  78. doi Effects of morphine on rat behaviour in the elevated plus maze: the role of central amygdala dopamine receptors
    Ameneh Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran
    Behav Brain Res 202:171-8. 2009
    ..In conclusion, these findings suggest that the central amygdala dopaminergic mechanisms, probably via D(1)/D(2) receptors, may be involved in the modulation of morphine-induced anxiolytic-like behaviour in rat...
  79. doi Involvement of dorsal hippocampal nicotinic receptors in the effect of morphine on memory retrieval in passive avoidance task
    Lotfollah Khajehpour
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran
    Eur J Pharmacol 584:343-51. 2008
    ..These results suggest that nicotinic acetylcholine receptors of the hippocampal CA1 regions may play an important role in morphine-induced amnesia and morphine state-dependent memory...
  80. ncbi Ethanol state-dependent memory: involvement of dorsal hippocampal muscarinic and nicotinic receptors
    Ameneh Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, P O Box 14155 6455, Tehran, Iran
    Neurobiol Learn Mem 89:441-7. 2008
    ..These findings implicate the involvement of a dorsal hippocampal cholinergic mechanism in ethanol state-dependent memory and also it can be concluded that there may be a cross-state dependency between ethanol and acetylcholine...
  81. ncbi Involvement of dopamine D2 receptors of the central amygdala on the acquisition and expression of morphine-induced place preference in rat
    Ameneh Rezayof
    Department of Biology, Faculty of Science, Tehran University, Tehran, Iran
    Pharmacol Biochem Behav 74:187-97. 2002
    ..The injection of sulpiride (1 and 5 microg/rat) abolished the expression of morphine-induced CPP. It is concluded that the CeA DA D2-like receptors may play an active role in morphine reward...
  82. doi Nicotinic acetylcholine receptors of the ventral tegmental area are involved in mediating morphine-state-dependent learning
    Ameneh Rezayof
    Department of Animal Bioliogy, School of Biology, College of Science, University of Tehran, P O Box 4155 6455, Tehran, Iran
    Neurobiol Learn Mem 90:255-60. 2008
    ..5 and 1microg/rat, intra-VTA) reversed the effect of nicotine on morphine response. The results indicate that nACh receptors in the VTA participate in the modulation of morphine-induced recovery of memory, on the test day...
  83. ncbi N-Methyl-D-aspartate receptors in the ventral tegmental area are involved in retrieval of inhibitory avoidance memory by nicotine
    Shamseddin Ahmadi
    Department of Animal Biology, School of Biology, University College of Science, University of Tehran, Tehran, Iran
    Neurobiol Learn Mem 88:352-8. 2007
    ..Our data indicate that NMDA receptors in the VTA are involved in the reversing effect of nicotine on morphine induced state-dependency...
  84. ncbi Influence of nitric oxide on morphine-induced amnesia and interactions with dopaminergic receptor agents
    Ameneh Rezayof
    School of Biology, University College of Science, University of Tehran, Tehran, Iran
    Physiol Behav 88:124-31. 2006
    ..It may be concluded that the morphine-induced impairment of memory formation can be prevented by nitric oxide donor and, in this effect, dopaminergic mechanism is involved...
  85. ncbi Involvement of dopamine receptors of the dorsal hippocampus on the acquisition and expression of morphine-induced place preference in rats
    Ameneh Rezayof
    Department of Biology, Faculty of Science, Tehran University, Tehran, Iran
    J Psychopharmacol 17:415-23. 2003
    ..Sulpiride, but not other drugs, increased locomotion when used before testing. It is concluded that dorsal hippocampal dopamine receptors may play an active role in morphine reward...
  86. doi Effects of cannabinoids infused into the dorsal hippocampus upon memory formation in 3-days apomorphine-treated rats
    Mohammad Nasehi
    Department of Biology, Faculty of Basic Sciences, Islamic Azad University, Garmsar Branch, Semnan, Iran
    Neurobiol Learn Mem 92:391-9. 2009
    ..02, 0.07 and 0.1 mg/kg/day x 3-days, S.C.), was ineffective in this respect. The results suggest that subchronic apomorphine treatment may induce dopamine D2 receptor sensitization, which in turn prevented amnesia induced by WIN55,212-2...
  87. ncbi On the mechanism of carbamazepine-induced antinociception in the formalin test
    Mousa Sahebgharani
    Department of Pharmacology, School of Medicine Tehran University of Medical Sciences, Tehran, Iran
    Int J Neurosci 116:1097-113. 2006
    ..None of the aforementioned drugs could alter the antinociceptive response of carbamazepine in the formalin test. It is concluded that sodium channel mechanisms may be involved partly in the antinociceptive induced by carbamazepine...
  88. ncbi Effects of clozapine and sulpiride on morphine state-dependent memory in the step-down passive avoidance test
    Nazanin Malekmohamadi
    Department of Pharmacology, School of Medicine and Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacology 79:149-53. 2007
    ..In conclusion, the inhibition of improvement of memory retrieval by morphine treatment on the test day by the two dopamine receptor antagonists seems to be induced through two different receptor mechanisms...
  89. doi Role of the central amygdala GABA-A receptors in morphine state-dependent memory
    Yassaman Rassouli
    Institute for Cognitive Science Studies, Tehran, Iran
    Life Sci 86:887-93. 2010
    ..In the present experiments, the effects of bilateral microinjections of the GABA-A receptor agonist and/or antagonist into the central amygdala (CeA) on morphine state-dependent memory were examined...
  90. ncbi The influence of NMDA receptor agonist and antagonist on morphine state-dependent memory of passive avoidance in mice
    Majid Jafari-Sabet
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Life Sci 78:157-63. 2005
    ..Conversely, DL-AP5 (1, 3.2 and 10 microg/mouse, i.c.v.) inhibited morphine-induced memory recall. It is concluded that NMDA receptors may be involved, at least in part, in morphine state-dependent learning in mice...
  91. ncbi Dorsal hippocampal dopamine receptors are involved in mediating ethanol state-dependent memory
    Ameneh Rezayof
    School of Biology, University College of Science, University of Tehran, Tehran, Iran
    Life Sci 80:285-92. 2007
    ..These findings implicate the involvement of a dorsal hippocampal dopaminergic mechanism in EtOH state-dependent memory and also it can be concluded that there may be a cross-state dependency between EtOH and dopamine...
  92. doi Morphine-induced behavioral sensitization increased the mRNA expression of NMDA receptor subunits in the rat amygdala
    Zargham Sepehrizadeh
    Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Tehran, Tehran, Iran
    Pharmacology 81:333-43. 2008
    ..Meanwhile, it has previously been reported that the amygdala is involved in behavioral sensitization. Thus, it can be concluded that the increase in NMDA receptor expression is associated with morphine-induced behavioral sensitization...
  93. doi Nicotine improves ethanol-induced memory impairment: the role of dorsal hippocampal NMDA receptors
    Ameneh Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran
    Life Sci 86:260-6. 2010
    ..The current study was undertaken to determine the role of dorsal hippocampal N-methyl-d-aspartate (NMDA) receptors in nicotine's effect on impairment of memory by ethanol...
  94. doi Inhibition of dorsal hippocampal nitric oxide synthesis potentiates ethanol-induced state-dependent memory in mice
    Ameneh Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran
    Behav Brain Res 209:189-95. 2010
    ..The ensemble of these observations suggests that ETOH-induced state-dependent memory can be modulated through the dorsal hippocampal nitric oxide system...
  95. doi Modulation of ethanol state-dependent learning by dorsal hippocampal NMDA receptors in mice
    Ameneh Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, P O Box 4155 6455, Tehran, Iran
    Alcohol 42:667-74. 2008
    ..25, 0.5, and 1 microg/mouse) alone did not affect memory retention. It may be concluded that dorsal hippocampal NMDA receptors are involved in mediating ethanol state-dependent learning...
  96. ncbi Morphine-induced place preference: involvement of the central amygdala NMDA receptors
    Ameneh Rezayof
    School of Biology, University College of Science, University of Tehran, P O Box 14155 6455, Tehran, Iran
    Brain Res 1133:34-41. 2007
    ..These results suggest that the NMDA receptor mechanisms in the central amygdala may be involved in the acquisition and expression of morphine-induced place preference...
  97. doi The amygdala modulates morphine-induced state-dependent memory retrieval via muscarinic acetylcholine receptors
    A Rezayof
    Department of Animal Biology, School of Biology, College of Science, University of Tehran, Enghelab Avenue, PO Box 4155 6455, Tehran, Iran
    Neuroscience 160:255-63. 2009
    ..In view of the known actions of the drugs used, the present data point to the involvement of amygdala muscarinic acetylcholine receptors in morphine-induced state-dependent memory retrieval...
  98. ncbi Effect of alpha-adrenoceptor agents on imipramine-induced antinociception in nerve-ligated mice
    M Sahebgharani
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Eur Neuropsychopharmacol 11:99-104. 2001
    ..However, the alpha(1)-adrenoceptor antagonist, prazosin, did not alter imipramine response. It may be concluded that imipramine induced antinociception in both intact and nerve-ligated mice through an alpha(2)-adrenoceptor mechanism(s)...
  99. ncbi Effect of alpha-adrenoceptor agonists and antagonists on imipramine-induced antinociception in the rat formalin test
    Mohammed Reza Zarrindast
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacology 64:201-7. 2002
    ..5 microg/rat, ICV) caused more inhibition of the response of imipramine or imipramine plus clonidine. Therefore, it is concluded that alpha(2)-adrenoceptor mechanism may be involved in the imipramine-induced antinociception...