Research Topics

Genomes and Genes


Mohammad Ali Sahraian


Affiliation: Tehran University of Medical Sciences
Country: Iran


  1. Roostaei T, Sadaghiani S, Park M, Mashhadi R, Nazeri A, Noshad S, et al. Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis. Neurology. 2016;86:410-7 pubmed publisher
    ..Overall, our findings add to the emerging evidence that suggests that sodium channel NaV1.8 could serve as a target for future drug-based interventions to treat cerebellar dysfunction in MS. ..
  2. Abdollahpour I, Nedjat S, Salimi Y, Moradzadeh R, Mansournia M, Sahraian M, et al. No association between socioeconomic status and risk of multiple sclerosis: A population-based incident case-control study in a developing country. Mult Scler Relat Disord. 2018;25:292-296 pubmed publisher
    ..575). We did not identify an association between household SES during adolescence, parental education levels, and a subsequent risk of developing MS in an Iranian population. ..
  3. Roostaei T, Nazeri A, Sahraian M, Minagar A. The human cerebellum: a review of physiologic neuroanatomy. Neurol Clin. 2014;32:859-69 pubmed publisher
    ..This article describes the cerebellar gross and histologic neuroanatomy in relation to its function, and the relevance of cerebellar circuitry and firing patterns to motor learning. ..
  4. Koolaji S, Allahabadi N, Ahmadi A, Eskandarieh S, Moghadasi A, Azimi A, et al. Anti-JC virus antibody sera positivity and index value among patients with multiple sclerosis may be correlated with age, sex, and area of residence. J Neurovirol. 2018;24:570-576 pubmed publisher
    ..Only age of onset and cold area of residency were related to the index. No significant difference was observed between type, dosage, and duration of previous immunosuppressant drugs and anti-JCV antibody positivity and index value. ..
  5. Mohajer B, Abbasi N, Pishgar F, Abdolalizadeh A, Ebrahimi H, Razaviyoun T, et al. HLA-DRB1 polymorphism and susceptibility to multiple sclerosis in the Middle East North Africa region: A systematic review and meta-analysis. J Neuroimmunol. 2018;321:117-124 pubmed publisher
    ..8 and OR=1.9), while DRB1*07 and DRB1*11 were protective (OR=0.56 and OR=0.67). Similar but non-significant trends were seen among alleles, which in sum coincides with a Caucasian-like pattern. ..
  6. Moghadasi A, Pourmand S, Sharifian M, Minagar A, Sahraian M. Behavioral Neurology of Multiple Sclerosis and Autoimmune Encephalopathies. Neurol Clin. 2016;34:17-31 pubmed publisher
    ..Although many studies have been performed in this regard, it seems that combining cognitive evaluations with other outcome measures in MS will enhance the understanding of neurobehavioral changes in MS. ..
  7. Baghbanian S, Asgari N, Sahraian M, Moghadasi A. A comparison of pediatric and adult neuromyelitis optica spectrum disorders: A review of clinical manifestation, diagnosis, and treatment. J Neurol Sci. 2018;388:222-231 pubmed publisher
    ..However, the proposed criteria need validation in pediatric patients. This strategy poses challenges to the study design in clinical trials in pediatric NMOSD patients. ..