Manouchehr Nakhjavani

Summary

Affiliation: Tehran University of Medical Sciences
Country: Iran

Publications

  1. doi request reprint Diabetes induces gender gap on LCAT levels and activity
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Life Sci 92:51-4. 2013
  2. pmc Gender difference in albuminuria and ischemic heart disease in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Clin Med Res 10:51-6. 2012
  3. doi request reprint The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Gene 498:107-11. 2012
  4. doi request reprint Metformin restores the correlation between serum-oxidized LDL and leptin levels in type 2 diabetic patients
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Redox Rep 16:193-200. 2011
  5. pmc Serum heat shock protein 70 and oxidized LDL in patients with type 2 diabetes: does sex matter?
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Cell Stress Chaperones 16:195-201. 2011
  6. doi request reprint Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Lipids 45:321-7. 2010
  7. doi request reprint ADMA is a correlate of insulin resistance in early-stage diabetes independent of hs-CRP and body adiposity
    M Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Ann Endocrinol (Paris) 71:303-8. 2010
  8. pmc Increased serum HSP70 levels are associated with the duration of diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Cell Stress Chaperones 15:959-64. 2010
  9. ncbi request reprint Type 2 diabetes mellitus duration: an independent predictor of serum malondialdehyde levels
    M Nakhjavani
    Endocrinology and Metabolism Research Centre, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran 14197 33141, Iran
    Singapore Med J 51:582-5. 2010
  10. doi request reprint Oxidized low-density lipoprotein is negatively correlated with lecithin-cholesterol acyltransferase activity in type 2 diabetes mellitus
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Am J Med Sci 341:92-5. 2011

Collaborators

Detail Information

Publications70

  1. doi request reprint Diabetes induces gender gap on LCAT levels and activity
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Life Sci 92:51-4. 2013
    ..Here we aimed to study serum LCAT levels and LCAT activity in men and women with type 2 diabetes (T2DM) as well as healthy controls...
  2. pmc Gender difference in albuminuria and ischemic heart disease in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Clin Med Res 10:51-6. 2012
    ..We questioned whether gender influences the albuminuria-ischemic heart disease relationship in patients with type 2 diabetes...
  3. doi request reprint The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Gene 498:107-11. 2012
    ..They are both inhibitors of nitric oxide synthase (NOS). The aim of this study was to evaluate the correlation between ADMA and HSP70, in patients with type 2 diabetes with respect to serum levels of C reactive protein (CRP)...
  4. doi request reprint Metformin restores the correlation between serum-oxidized LDL and leptin levels in type 2 diabetic patients
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Redox Rep 16:193-200. 2011
    ..We also studied the effect of metformin therapy on the correlation between serum ox-LDL and leptin levels in patients with newly diagnosed diabetes...
  5. pmc Serum heat shock protein 70 and oxidized LDL in patients with type 2 diabetes: does sex matter?
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Cell Stress Chaperones 16:195-201. 2011
    ..We suggest that diabetes induces an immune response and impairs cellular defense mechanisms against oxidative stress more commonly in women with type 2 diabetes than in men...
  6. doi request reprint Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Lipids 45:321-7. 2010
    ..Our findings highlight that possibly more attention should be focused on markers of oxidative stress in the management of lipids in diabetic patients...
  7. doi request reprint ADMA is a correlate of insulin resistance in early-stage diabetes independent of hs-CRP and body adiposity
    M Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Ann Endocrinol (Paris) 71:303-8. 2010
    ....
  8. pmc Increased serum HSP70 levels are associated with the duration of diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Cell Stress Chaperones 15:959-64. 2010
    ..Higher HSP70 in prolonged diabetes versus newly diagnosed diabetes may be an indicator of metabolic derangement in the course of diabetes...
  9. ncbi request reprint Type 2 diabetes mellitus duration: an independent predictor of serum malondialdehyde levels
    M Nakhjavani
    Endocrinology and Metabolism Research Centre, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran 14197 33141, Iran
    Singapore Med J 51:582-5. 2010
    ..Malondialdehyde (MDA) plays a major role in low-density lipoprotein modification. This study aimed to evaluate whether DM duration is an independent predictor of serum MDA levels...
  10. doi request reprint Oxidized low-density lipoprotein is negatively correlated with lecithin-cholesterol acyltransferase activity in type 2 diabetes mellitus
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Am J Med Sci 341:92-5. 2011
    ....
  11. doi request reprint Serum lipoprotein(a) levels are greater in female than male patients with type-2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Lipids 46:349-56. 2011
    ..The increase in women was independent of menopause. The level of serum Lp(a) had no correlation with lipid parameters in men or women...
  12. pmc Albuminuria and its correlates in an Iranian type 2 diabetic population
    Manouchehr Nakhjavani
    Endocrine and Metabolism Research Center, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Lipids Health Dis 7:28. 2008
    ..To study the prevalence and correlates of increased urinary albumin excretion (UAE) in an Iranian type 2 diabetic population...
  13. ncbi request reprint Oxidized low-density lipoprotein is associated with viral load and disease activity in patients with chronic hepatitis C
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Clin Res Hepatol Gastroenterol 35:111-6. 2011
    ..The purpose of this study was to determine the serum level of oxidized low-density lipoprotein (ox-LDL), and evaluate its association with different clinically valuable parameters of liver disease in patients with chronic hepatitis C...
  14. ncbi request reprint Association of macroalbuminuria with oxidized LDL and TGF-beta in type 2 diabetic patients: a case-control study
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Int Urol Nephrol 42:487-92. 2010
    ....
  15. doi request reprint Changes in growth hormone and insulin-like growth factor-I levels in the acute stage after open heart surgery and at the time of discharge
    M Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Medical Sciences University of Tehran, Iran
    Exp Clin Endocrinol Diabetes 117:413-6. 2009
    ..This study aimed to investigate changes in GH/IGF-I axis in adults undergoing open heart surgery...
  16. pmc Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Centre EMRC, Vali Asr Hospital, Tehran, Iran
    Br J Clin Pharmacol 68:634-7. 2009
    ..To investigate the effects of spironolactone on serum lipids in women with hirsutism over a 3-month period...
  17. doi request reprint Association of oxidized low-density lipoprotein and transforming growth factor-beta in type 2 diabetic patients: a cross-sectional study
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Transl Res 153:86-90. 2009
    ..308, P = 0.007). In conclusion, this study demonstrated that ox-LDL is significantly correlated to TGF-beta in type 2 diabetic patients...
  18. doi request reprint The value of visfatin in the prediction of metabolic syndrome: a multi-factorial analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Cardiovasc Transl Res 5:541-6. 2012
    ..These findings may contribute to our current knowledge about visfatin in metabolic syndrome...
  19. ncbi request reprint Association between oxidant/antioxidant markers and proteinuria in type 2 diabetes: results in 142 patients
    Armin Rashidi
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Nephrol 22:733-8. 2009
    ..The relationship between oxidant/antioxidant markers and proteinuria in type 2 diabetes is not clear, partly because of the potentially confounding effect of renal function which tends to become impaired during the course of diabetes...
  20. doi request reprint Association of serum leptin levels with homeostasis model assessment-estimated insulin resistance and metabolic syndrome: the key role of central obesity
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 7:447-52. 2009
    ..This study evaluated the relationship between leptin, metabolic syndrome, and insulin resistance in an Iranian population and further investigated whether this relationship is confounded by obesity or central obesity...
  21. doi request reprint Association of plasma leptin levels and insulin resistance in diabetic women: a cross-sectional analysis in an Iranian population with different results in men and women
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Gynecol Endocrinol 27:14-9. 2011
    ..The objective of this study was to assess the association of serum leptin levels with insulin resistance (IR), metabolic syndrome (MetS), lipid levels, and glucose control in an Iranian type 2 diabetic population...
  22. doi request reprint Optimal threshold of homeostasis model assessment for insulin resistance in an Iranian population: the implication of metabolic syndrome to detect insulin resistance
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Res Clin Pract 84:279-87. 2009
    ..In this study, the cut point of HOMA to detect IR was lower than other populations. IR is an unyielding correlate of MetS; but definitions of MetS are insensitive measures of IR in our population...
  23. ncbi request reprint Comparing abilities of different lipid measures in diagnosis of insulin resistance: a Survey of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 10:63-9. 2012
    ..Dyslipidemia is a distinguishing characteristic of subjects with insulin resistance. Our aim was to determine the predictive abilities and appropriate cutoffs of different lipid variables for insulin resistance...
  24. doi request reprint Clustering of leptin and physical activity with components of metabolic syndrome in Iranian population: an exploratory factor analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Endocrine 38:206-13. 2010
    ..Further, this study suggests that physical activity influences MetS components via modulation of the main underlying pathophysiologic pathway of this syndrome...
  25. doi request reprint Appropriate BMI cut-off values for identification of metabolic risk factors: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Ali Zandieh
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Ann Hum Biol 39:484-9. 2012
    ..To determine the appropriate threshold of body mass index (BMI) associated with increased risk of cardiovascular diseases in a large representative sample of an Iranian population...
  26. ncbi request reprint Correlates of ACE activity in macroalbuminuric type 2 diabetic patients treated with chronic ACE inhibition
    Abdolrahim Nikzamir
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences University of Tehran, Iran
    Nephrol Dial Transplant 23:1274-7. 2008
    ..In conclusion, the D allele is a significant independent correlate of ACE activity in macroalbuminuric type 2 diabetic Iranian patients under long-term ACE inhibition...
  27. doi request reprint HOMA-estimated insulin resistance is associated with hypertension in Iranian diabetic and non-diabetic subjects
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences University of Tehran, Tehran, Iran
    Clin Exp Hypertens 30:297-307. 2008
    ..102, CI 95% = 1.009-1.203, p < 0.05 and odds ratio = 1.328, CI 95% = 1.116-1.580, p < 0.01, respectively). In conclusion, this study showed that IR is associated with HTN in Iranian diabetic and non-diabetic subjects...
  28. doi request reprint Comparative effects of pioglitazone and metformin on oxidative stress markers in newly diagnosed type 2 diabetes patients: a randomized clinical trial
    Hossein Mirmiranpour
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Electronic address
    J Diabetes Complications 27:501-7. 2013
    ..Recent studies have suggested that pioglitazone exerts anti-oxidant properties which may countervail oxidative stress (OS). We aimed to elucidate the effects of pioglitazone on OS modulation and to compare its effects with metformin...
  29. pmc Physical inactivity is correlated with levels of quantitative C-reactive protein in serum, independent of obesity: results of the national surveillance of risk factors of non-communicable diseases in Iran
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Health Popul Nutr 30:66-72. 2012
    ..Physical activity (of both moderate and vigorous intensity) is inversely associated with the quantitative CRP levels in serum, independent of diabetes and body adiposity...
  30. ncbi request reprint Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with metabolic syndrome in Iranians with type 2 diabetes mellitus
    Abdolrahim Nikzamir
    Endocrinology and Metabolism Research Center EMRC, Vali e Asr Hospital, Tehran, Iran Nikzamirar yahoo com
    Arch Iran Med 11:3-9. 2008
    ..The objective of this study was to investigate whether angiotensin-converting enzyme gene insertion/deletion polymorphism is associated with metabolic syndrome in Iranians with type 2 diabetes mellitus...
  31. ncbi request reprint The inverse relation of CA-125 to diabetes, metabolic syndrome, and associated clinical variables
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 11:256-61. 2013
    ..We aimed to evaluate the association of carbohydrate antigen 125 (CA-125; also known as cancer antigen 125) with various anthropometric and metabolic measures and also with diabetes and metabolic syndrome...
  32. doi request reprint The lost correlation between leptin and CRP in type 2 diabetes
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 24:53-9. 2013
    ..584, p<0.01). Statin treatment did not have any significant effect on the results. This is the first report demonstrating the restorative role of metformin on the leptin-CRP correlation in patients with newly diagnosed diabetes...
  33. doi request reprint Effects of metformin on markers of oxidative stress and antioxidant reserve in patients with newly diagnosed type 2 diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Nutr 32:179-85. 2013
    ..Effects of metformin on markers of oxidative stress, antioxidant reserve, and HDL-c associated antioxidant enzymes were investigated...
  34. ncbi request reprint HbA1c negatively correlates with LCAT activity in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Imam Khomeini Medical Complex, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Diabetes Res Clin Pract 81:38-41. 2008
    ..The purpose of this study was to determine the independent correlates of LCAT activity in DM2 patients...
  35. doi request reprint Leptin cut-off values for determination of metabolic syndrome: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Endocrine 40:117-23. 2011
    ..The diagnostic accuracy of these values in identifying MetS was similar to that of insulin resistance. Therefore, leptin is comparable to insulin resistance in identifying MetS and can be used as single predictor of MetS...
  36. doi request reprint Insulin resistance is independently associated with liver aminotransferases in diabetic patients without ultrasound signs of nonalcoholic fatty liver disease
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 9:111-7. 2011
    ..The aim of this study was to assess the association between elevated liver enzymes and insulin resistance in diabetic subjects without ultrasound signs of nonalcoholic fatty liver disease (NAFLD) (i.e., with less than 30% steatosis)...
  37. doi request reprint Inconsistency in albuminuria predictors in type 2 diabetes: a comparison between neural network and conditional logistic regression
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Transl Res 161:397-405. 2013
    ..Our neural network model complements the current risk factor models to improve the care of patients with diabetes...
  38. doi request reprint Apolipoproteins a-I and B as components of metabolic syndrome with respect to diabetes status: a factor analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 10:280-5. 2012
    ..The aim of the current study was to elucidate the clustering pattern of metabolic syndrome components along with apolipoproteins (Apo) A-I and B in diabetic and nondiabetic subjects...
  39. doi request reprint Menopause is an independent predictor of metabolic syndrome in Iranian women
    Radina Eshtiaghi
    AJA University of Medical Science, 3th floor, Endocrine Research Center, Emam Reza Hospital 501 AJA, Etemad Zadeh Ave, Fatemi St, Tehran, Iran
    Maturitas 65:262-6. 2010
    ..Postmenopausal status may explain in part the cause of acceleration of CVD with aging. The purpose of this study was to investigate the relation of menopause and metabolic syndrome independent of aging among Iranian women...
  40. ncbi request reprint Gender-specific changes in physical activity pattern in Iran: national surveillance of risk factors of non-communicable diseases (2007-2011)
    Jalil Koohpayehzadeh
    Center for Disease Control, Tehran, Iran
    Int J Public Health 59:231-41. 2014
    ..This study describes the gender-specific pattern of physical activity (PA) in Iran 2011. The 4-year changes in PA levels (domains) are also determined according to the Iran's national surveys conducted on 2007 and 2011...
  41. doi request reprint Treatment with pioglitazone is associated with decreased preprandial ghrelin levels: a randomized clinical trial
    Shervin Taslimi
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Peptides 40:89-92. 2013
    ..The effect of pioglitazone on ghrelin is independent of changes in body weight, body mass index, plasma insulin, insulin resistance, or glucose control...
  42. doi request reprint Vascular endothelial growth factor (VEGF) +405 C/G polymorphism is associated with essential hypertension in a population from Tehran of Iran
    Amir Abbas Hamedian
    Health Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Mol Biol Rep 39:6213-8. 2012
    ..200-2.086; P = 0.001). In conclusion, +405 VEGF C/G SNP is associated with EH in patients with diabetes, suggesting presence of G allele and GG or CG genotype confer susceptibility towards EH...
  43. doi request reprint Physical activity is correlated with serum leptin independent of obesity: results of the national surveillance of risk factors of noncommunicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran 14107 33141, Iran
    Metabolism 59:1730-5. 2010
    ..In conclusion, our results demonstrated an inverse association between leptin concentrations and PA independent of age, sex, smoking, and body adiposity. Our results point to the regulatory effects of PA on serum leptin...
  44. ncbi request reprint Effect of crocin on the insulin resistance and lipid profile of streptozotocin-induced diabetic rats
    Saeed Shirali
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    Phytother Res 27:1042-7. 2013
    ..The treatments were also effective in decreasing HbA1c and microalbuminuria, as well as homeostatic model assessment for insulin resistance as a measure of insulin resistance in the diabetic rats...
  45. doi request reprint Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Regul Pept 182:1-6. 2013
    ..To assess the effects of two commonly used oral hypoglycemic medications metformin and pioglitazone on serum concentrations of omentin and leptin in patients with newly diagnosed type 2 diabetes...
  46. ncbi request reprint Association of serum cortisol levels with parameters of metabolic syndrome in men and women
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Invest Med 34:E131-7. 2011
    ..The purpose of this study was to compare serum cortisol levels, and its correlation with serum leptin levels, between men and women with and without metabolic syndrome...
  47. doi request reprint Serum visfatin is associated with type 2 diabetes mellitus independent of insulin resistance and obesity
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Res Clin Pract 91:154-8. 2011
    ..The aim of this study was to evaluate the association of serum visfatin, adiponectin and leptin with 2 diabetes mellitus (T2DM) in the context of the role of obesity or insulin resistance, which is not well understood...
  48. doi request reprint Insulin resistance and breast carcinogenesis: a cross-sectional study among Iranian women with breast mass
    Mehrshad Abbasi
    Endocrinology and Metabolism Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 8:411-6. 2010
    ..001, partial eta squared = 0.11]. We conclude that the noted linkage between insulin resistance and breast cancer may indicate an underlying pathology of mammary carcinogenesis...
  49. ncbi request reprint Accuracy of anthropometric parameters in identification of high-risk patients predicted with cardiovascular risk models
    Alireza Esteghamati
    Department of Endocrinology and Metabolism, Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Am J Med Sci 346:26-31. 2013
    ..Early detection of the patients' high risk for developing cardiovascular disease (CVD) is a primary care priority. Simple-to-use screening tools derived from anthropometric parameters and obesity-related indices could serve this purpose...
  50. ncbi request reprint The relationship between the insertion/deletion polymorphism of the ACE gene and hypertension in Iranian patients with type 2 diabetes
    Manouchehr Nakhjavani
    Endocrine and Metabolism Research Center, Vali Asr Hospital, and Department of Biochemistry, School of Medicine, Medical Sciences, University of Tehran, No 12, Aramesh Alley, Mellat Park, Tehran, Iran
    Nephrol Dial Transplant 22:2549-53. 2007
    ..The aim of this study was to evaluate for the first time the possible association between I/D polymorphism and hypertension in an Iranian diabetic adult population...
  51. pmc Prevalence of diabetes and other cardiovascular risk factors in an Iranian population with acute coronary syndrome
    Alireza Esteghamati
    Faculty of Medicine, Tehran University of Medical Sciences, Keshavarz Blvd, Tehran, Iran
    Cardiovasc Diabetol 5:15. 2006
    ....
  52. ncbi request reprint The degree of resistance of erythrocyte membrane cytoskeletal proteins to supra-physiologic concentrations of calcium: an in vitro study
    Ebrahim Mostafavi
    Department of Laboratory Medicine, Mirza Kouchak Khan Women s Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Membr Biol 247:695-701. 2014
    ..Cumulative effects of disrupted calcium homeostasis on cytoskeletal proteins need to be further investigated at extended periods of time in disease states. ..
  53. doi request reprint Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005-2011
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Electronic address
    Diabetes Res Clin Pract 103:319-27. 2014
    ..To estimate the prevalence and trends of diabetes mellitus (DM) and impaired fasting glucose (IFG), 2005-2011, and to determine the contribution of obesity to DM prevalence...
  54. ncbi request reprint Risk of coronary heart disease associated with metabolic syndrome and its individual components in Iranian subjects: A matched cohort study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran Electronic address
    J Clin Lipidol 8:279-86. 2014
    ..Moreover, we aimed to define the most hazardous MetS components...
  55. pmc Heat shock protein 70 and albuminuria in patients with type 2 diabetes: a matched case control study
    Afsaneh Morteza
    Endocrinology and Diabetes Division, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Cell Stress Chaperones 18:815-9. 2013
    ..The odds ratio of HSP70 in the prediction of albuminuria was (28.69 (3.2-250.1), p = 0.002). In conclusion, we have shown an increased HSP70 levels in diabetic patients with albuminuria. ..
  56. doi request reprint Association of +45(T/G) and +276(G/T) polymorphisms in the adiponectin gene with coronary artery disease in a population of Iranian patients with type 2 diabetes
    Alireza Esteghamati
    Endocrine Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Mol Biol Rep 39:3791-7. 2012
    ..Also Haplotype analysis showed that two haplotypes 45T-276T and 45G-276T were associated with a decreased risk of CAD...
  57. pmc Metabolic syndrome is linked to a mild elevation in liver aminotransferases in diabetic patients with undetectable non-alcoholic fatty liver disease by ultrasound
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetol Metab Syndr 2:65. 2010
    ..In this study, we aimed to assess the relationship between circulating liver enzymes and MetS in a relatively large sample of patients with diabetes...
  58. pmc Optimal cut-off of homeostasis model assessment of insulin resistance (HOMA-IR) for the diagnosis of metabolic syndrome: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Nutr Metab (Lond) 7:26. 2010
    ..The aim of the present study is to establish the optimal cut-off at the national level in the Iranian population with and without diabetes...
  59. doi request reprint The effect of hot-tub therapy on serum Hsp70 level and its benefit on diabetic rats: a preliminary report
    S Zahra Bathaie
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    Int J Hyperthermia 26:577-85. 2010
    ..To carry out a preliminary study examining the efficacy of long-term hot-tub therapy (HTT) in the improvement of diabetic complications on streptozotocin-induced diabetic rats...
  60. doi request reprint Protective role of calcium ion against stress-induced osmotic fragility of red blood cells in patients with type 2 diabetes mellitus
    Ebrahim Mostafavi
    Department of Laboratory Medicine, Mirza Kouchak Khan Women s Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Clin Hemorheol Microcirc 53:239-45. 2013
    ..We showed for the first time that controlling calcium ion concentration in patients with diabetes could exert a protective and beneficial role against membrane-affecting conditions...
  61. doi request reprint Patterns of fruit and vegetable consumption among Iranian adults: a SuRFNCD-2007 study
    Alireza Esteghamati
    School of Medicine, Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Br J Nutr 108:177-81. 2012
    ..A high prevalence of low F&V consumption in the Iranian adult population was documented. These findings may guide health policy makers in developing specific plans to encourage adequate F&V intake...
  62. ncbi request reprint Constant magnetic field of 50 mT does not affect weight gain and blood glucose level in BALB/c mice
    Mehrshad Abbasi
    Endocrine Research Center, Vali Asr Hospital, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Med Sci Monit 13:BR151-4. 2007
    ..01- and 0.001-Tesla and weight loss in 0.9-Tesla constant electromagnetic fields. This study aimed to examine the effect of a 0.05-Tesla constant magnetic field on weight gain and blood glucose homeostasis in BALB/c mice...
  63. doi request reprint Serum interleukin-1 and interleukin-6 are correlated neither with oxidized low density lipoprotein, nor with low-grade inflammation in patients with type 2 diabetes
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 22:107-12. 2011
    ..We measured serum high sensitivity CRP (hs-CRP) levels in order to define basal inflammation in patients and controls...
  64. ncbi request reprint Diabetes mellitus following pituitary adenomectomy in euglycemic patients with acromegaly
    Bagher Larijani
    Endocrinology and Metabolism Research Centre EMRC, Tehran University of Medical Sciences TUMS, Iran
    J Coll Physicians Surg Pak 15:430-2. 2005
    ..We report 7 patients who developed diabetes mellitus after pituitary adenomectomy. Regular measuring of blood glucose in post-pituitary surgery patients is recommended as a necessary step even in the previously normoglycaemics...
  65. doi request reprint Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Nephrol Dial Transplant 28:2823-33. 2013
    ..This study was designed to assess the long-term efficacy of SPR/ARB combination in comparison with the standard ACE/ARB regimen in diabetic nephropathy...
  66. ncbi request reprint Investigation of the mechanism(s) involved in decreasing increased fibrinogen activity in hyperglycemic conditions using L-lysine supplementation
    Hossein Mirmiranpour
    Department of Clinical Biochemistry, Tehran University of Medical Sciences, Tehran, Iran
    Thromb Res 130:e13-9. 2012
    ..Its malfunction has been reported as a consequence of diabetic complications. In this study, the inhibitory effect of L-Lysine (Lys) on the nonenzymatic glycation of fibrinogen was investigated in both in vitro and in vivo conditions...
  67. ncbi request reprint Investigation of the mechanisms involved in the high-dose and long-term acetyl salicylic acid therapy of type I diabetic rats
    Akbar Jafarnejad
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, P O BOX 14115 111, Tehran, Iran
    J Pharmacol Exp Ther 324:850-7. 2008
    ..The improving effect of ASA on diabetic rats is mostly due to its role as a chemopreventive agent in the structural conservation and protection of proteins involved in diabetes pathogenesis...
  68. ncbi request reprint Are biochemical values predictive of adenoma's weight in primary hyperparathyroidism?
    Sepehr Hamidi
    School of Medicine, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    ANZ J Surg 76:882-5. 2006
    ..Preoperative laboratory findings may carry some predictive value about the size of the abnormal parathyroid tissue that needs to be removed in primary hyperparathyroidism...
  69. doi request reprint Molecular analysis of the RET proto-oncogene key exons in patients with medullary thyroid carcinoma: a comprehensive study of the Iranian population
    Ehsan Alvandi
    Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences TUMS, Tehran, Iran
    Thyroid 21:373-82. 2011
    ..Here, we present the first comprehensive genetic screening and analysis of MTC among Iranian families...