Reza Meshkani

Summary

Affiliation: Tehran University of Medical Sciences
Country: Iran

Publications

  1. doi request reprint Estrogen receptor alpha gene polymorphisms are associated with type 2 diabetes and fasting glucose in male subjects
    Reza Meshkani
    The Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR, Iran
    Mol Cell Biochem 359:225-33. 2012
  2. doi request reprint The relationship between uric acid and metabolic syndrome in normal glucose tolerance and normal fasting glucose subjects
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR Iran
    Acta Diabetol 48:79-88. 2011
  3. ncbi request reprint 1484insG polymorphism of the PTPN1 gene is associated with insulin resistance in an Iranian population
    Reza Meshkani
    Endocrinology and Metabolism Research Centre, Shariati Hospital, Tehran University of Medical Sciences, Tehran, I R Iran
    Arch Med Res 38:556-62. 2007
  4. ncbi request reprint Polymorphisms within the protein tyrosine phosphatase 1B (PTPN1) gene promoter: functional characterization and association with type 2 diabetes and related metabolic traits
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, I R Iran
    Clin Chem 53:1585-92. 2007
  5. doi request reprint Hydrodynamic-based delivery of PTP1B shRNA reduces plasma glucose levels in diabetic mice
    Sanaz Vakili
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Mol Med Rep 7:211-6. 2013
  6. doi request reprint Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells
    Gholamreza Taheripak
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran 1416753955, Iran
    Free Radic Biol Med 65:1435-46. 2013
  7. doi request reprint Palmitate enhances protein tyrosine phosphatase 1B (PTP1B) gene expression at transcriptional level in C2C12 skeletal muscle cells
    Narges Mohammadtaghvaei
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, P O Box 14115 331, Tehran, Iran
    Inflammation 34:43-8. 2011
  8. ncbi request reprint Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population
    Reza Meshkani
    Endocrinology and Metabolism Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Clin Chem Lab Med 45:477-82. 2007
  9. doi request reprint Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Biochem 42:1331-46. 2009
  10. doi request reprint Rosiglitazone, a PPARγ agonist, ameliorates palmitate-induced insulin resistance and apoptosis in skeletal muscle cells
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR, Iran
    Cell Biochem Funct 32:683-91. 2014

Collaborators

  • Khosrow Adeli
  • Shohreh Khatami
  • Ali Akbar Pourfathollah
  • Abolfazl Golestani
  • Bagher Larijani
  • Sattar Gorgani-Firuzjaee
  • Gholamreza Taheripak
  • Parvin Pasalar
  • Sanaz Vakili
  • Monireh Mani
  • Ahmad Nasimian
  • Asie Sadeghi
  • Salar Bakhtiyari
  • Narges Mohammadtaghvaei
  • Mostafa Haji Molla Hoseini
  • Saeideh Ahmadi
  • Maani Beigy
  • Zahra Zamani
  • Kayhan Azadmanesh
  • Taghi Golmohammadi
  • Masoumeh Rajabibazl
  • Shahnaz Khaghani
  • Shadi Sadat Seyyed Ebrahimi
  • Mohammad Taghikhani
  • Zahra Soheili
  • Sedigheh Amini
  • Shahram Samiee
  • Mahnaz Aghaiepour
  • Minoo Mohraz
  • Mahin Nikoogoftar

Detail Information

Publications17

  1. doi request reprint Estrogen receptor alpha gene polymorphisms are associated with type 2 diabetes and fasting glucose in male subjects
    Reza Meshkani
    The Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR, Iran
    Mol Cell Biochem 359:225-33. 2012
    ..37 (1.61-11.86), P=0.004]. No association was found between the XbaI polymorphism and diabetes in male group. Our results suggest that the ER1 polymorphisms might associate with T2D and fasting glucose among Iranian male subjects...
  2. doi request reprint The relationship between uric acid and metabolic syndrome in normal glucose tolerance and normal fasting glucose subjects
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR Iran
    Acta Diabetol 48:79-88. 2011
    ..General obesity was the major determinant of hyperuricemia in this population. The data from this study do not show the contribution of SUA as an additional component of the MetS...
  3. ncbi request reprint 1484insG polymorphism of the PTPN1 gene is associated with insulin resistance in an Iranian population
    Reza Meshkani
    Endocrinology and Metabolism Research Centre, Shariati Hospital, Tehran University of Medical Sciences, Tehran, I R Iran
    Arch Med Res 38:556-62. 2007
    ..The purpose of this study was to investigate the association of 1484insG polymorphism of the PTPN1 with obesity, insulin resistance, type 2 diabetes and other cardiovascular-related traits in an Iranian population...
  4. ncbi request reprint Polymorphisms within the protein tyrosine phosphatase 1B (PTPN1) gene promoter: functional characterization and association with type 2 diabetes and related metabolic traits
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, I R Iran
    Clin Chem 53:1585-92. 2007
    ..Polymorphisms in the coding sequence of PTPN1 have been variably associated with type 2 diabetes (T2D). We hypothesized that variations within the PTPN1 promoter might contribute to the development of T2D and related metabolic traits...
  5. doi request reprint Hydrodynamic-based delivery of PTP1B shRNA reduces plasma glucose levels in diabetic mice
    Sanaz Vakili
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Mol Med Rep 7:211-6. 2013
    ..However, further studies using non-viral carriers are required to deliver the plasmid safely into the liver. ..
  6. doi request reprint Protein tyrosine phosphatase 1B inhibition ameliorates palmitate-induced mitochondrial dysfunction and apoptosis in skeletal muscle cells
    Gholamreza Taheripak
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran 1416753955, Iran
    Free Radic Biol Med 65:1435-46. 2013
    ....
  7. doi request reprint Palmitate enhances protein tyrosine phosphatase 1B (PTP1B) gene expression at transcriptional level in C2C12 skeletal muscle cells
    Narges Mohammadtaghvaei
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, P O Box 14115 331, Tehran, Iran
    Inflammation 34:43-8. 2011
    ..These data suggest that while palmitate treatment significantly induced PTP1B expression at the transcriptional level, the presence of an inflammatory process exerted by macrophages can augment this effect in the muscle cells...
  8. ncbi request reprint Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population
    Reza Meshkani
    Endocrinology and Metabolism Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Clin Chem Lab Med 45:477-82. 2007
    ..However, this association has not been studied in Iranian subjects and we hypothesized that this variation might be associated with insulin resistance, type 2 diabetes and related metabolic traits in this population...
  9. doi request reprint Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Biochem 42:1331-46. 2009
    ..The metabolic syndrome is a constellation of common metabolic disorders that is associated with cardiovascular disease. Insulin resistance has a central role in the pathophysiology of metabolic syndrome...
  10. doi request reprint Rosiglitazone, a PPARγ agonist, ameliorates palmitate-induced insulin resistance and apoptosis in skeletal muscle cells
    Reza Meshkani
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR, Iran
    Cell Biochem Funct 32:683-91. 2014
    ..These data suggest that RSG protects skeletal muscle cells against palmitate-induced apoptosis and this effect appears to be mediated via the PPARγ-dependent and PTP1B-independent mechanisms...
  11. doi request reprint Protein tyrosine phosphatase 1B (PTP1B) modulates palmitate-induced cytokine production in macrophage cells
    Ahmad Nasimian
    The Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    Inflamm Res 62:239-46. 2013
    ..The aim of the study was to investigate the effect of PTP1B modulation on palmitate-induced cytokine production in macrophages...
  12. ncbi request reprint The relationship between homeostasis model assessment and cardiovascular risk factors in Iranian subjects with normal fasting glucose and normal glucose tolerance
    Reza Meshkani
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
    Clin Chim Acta 371:169-75. 2006
    ..We investigated the relationship between homeostasis model assessment of insulin resistance (HOMA-IR) with cardiovascular risk factors in Iranian subjects with normal fasting glucose (NFG) and normal glucose tolerance (NGT)...
  13. doi request reprint Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells
    Sattar Gorgani-Firuzjaee
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    Biochem Biophys Res Commun 464:441-6. 2015
    ..Taken together, these findings suggest that SHIP2 expression level is an important determinant of hepatic lipoapotosis and its inhibition can potentially be a target in treatment of hepatic lipoapoptosis in diabetic patients...
  14. pmc Homocysteine induces heme oxygenase-1 expression via transcription factor Nrf2 activation in HepG2 cell
    Monireh Mani
    Dept of Biochemistry, School of Medicine, Tehran University of Medical Science, Tehran, Iran
    Iran Biomed J 17:93-100. 2013
    ..Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcription factor Nrf2, a principal inducer of anti-oxidant and phase II-related genes...
  15. doi request reprint Palmitate induces SHIP2 expression via the ceramide-mediated activation of NF-κB, and JNK in skeletal muscle cells
    Sattar Gorgani-Firuzjaee
    Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran Student Scientific Research Center SSRC, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    Biochem Biophys Res Commun 450:494-9. 2014
    ..Here we investigated the effects of palmitate on SHIP2 expression and elucidated the underlying mechanisms in skeletal muscle cells...
  16. doi request reprint Leukocyte antigen-related inhibition attenuates palmitate-induced insulin resistance in muscle cells
    Sattar Gorgani-Firuzjaee
    Department of Biochemistry, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    J Endocrinol 215:71-7. 2012
    ..In conclusion, these results reveal that palmitate induces LAR expression in C2C12 cells. We also provided evidence that the inhibition of LAR attenuates palmitate-induced insulin resistance in myotubes...
  17. ncbi request reprint Evaluation of circulating natural type 1 interferon-producing cells in HIV/GBV-C and HIV/HCV coinfected patients: a preliminary study
    Mostafa Haji Molla Hoseini
    Department of Immunology, School of Medicine, Tarbiat Modarres University, Tehran, Iran
    Arch Med Res 38:868-75. 2007
    ..To address the possibility of immune-modulating effects of GBV-C coinfection in HIV patients, we evaluated interferon-producing cells in HIV/GBV-C coinfected patients and compared them to HIV-infected patients...