Mohammad Reza Khorramizadeh

Summary

Affiliation: Tehran University of Medical Sciences
Country: Iran

Publications

  1. ncbi request reprint Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters
    Mohammad Reza Khorramizadeh
    School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
    Int J Urol 12:637-43. 2005
  2. pmc Fabrication of docetaxel surfaced Fe3O4 magnetite nanoparticles and their cytotoxicity on 4 T1 breast cancer cells
    Mh Yazdi
    Department of Pharmaceutical Biotechnology and Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Daru 20:15. 2012
  3. ncbi request reprint Interaction of CpG-oligodeoxynucleotides with Toll like receptor 9 induces apoptosis and modulates metaloproteinase-2 activity in human intestinal epithelium
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Medical Sciences, University of Tehran, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:107-14. 2007
  4. ncbi request reprint Suppression of telomerase activity by pyrimethamine: implication to cancer
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Medical Sciences University of Tehran, P O Box 14155 6446, Tehran, Iran
    Iran Biomed J 11:223-8. 2007
  5. ncbi request reprint Dermal Wound Fibroblasts and Matrix Metaloproteinases (MMPs): Their Possible Role in Allergic Contact Dermatitis
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 3:7-11. 2004
  6. ncbi request reprint Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase
    Farshid Saadat
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Med Sci Monit 11:BR253-7. 2005
  7. doi request reprint Anionic linear-globular dendrimers: biocompatible hybrid materials with potential uses in nanomedicine
    Mohammad Shafiee Alavidjeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    J Mater Sci Mater Med 21:1121-33. 2010
  8. doi request reprint The in vivo antitumor activity of LHRH targeted methotrexate-human serum albumin nanoparticles in 4T1 tumor-bearing Balb/c mice
    Azade Taheri
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Int J Pharm 431:183-9. 2012
  9. ncbi request reprint Matrix metalloproteinase 2 secretion in WEHI 164 fibrosarcoma cells is nitric oxide-related and modified by morphine
    Ahmad Shariftabrizi
    Department of Pathobiology, Tehran University of Medical Sciences, Iran
    Eur J Pharmacol 530:33-9. 2006
  10. ncbi request reprint Chemoprevention by pyrimethamine
    Farshid Saadat
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Immunopharmacol Immunotoxicol 27:233-40. 2005

Collaborators

  • Abbas Mirshafiey
  • Ahmad Reza Dehpour
  • Rassoul Dinarvand
  • Ismaeil Haririan
  • Hassan Namazi
  • Mohammad Ali Faramarzi
  • Mohsin Raza
  • Elias Castanas
  • Salvatore Cuzzocrea
  • Mousa Sahebgharani
  • Shahnaz Khaghani
  • Farshid Saadat
  • Azade Taheri
  • Ahmad Shariftabrizi
  • Maryam Moazeni
  • Gohar Fakhfouri
  • Reza Rahimian
  • Nastaran Alizadeh
  • Sassan Rezaie
  • Hamid Eslami
  • Mh Yazdi
  • Shahram Ejtemaei Mehr
  • Fatemeh Atyabi
  • Laya Kafami
  • Mojtaba Shakibaie
  • Massih Bahar
  • Mohammad Shafiee Alavidjeh
  • Ahmad Reza Shahverdi
  • Mehdi Forouzandeh
  • Farnaz Safavifar
  • Mona Safaepour
  • Azar Berahmeh
  • Fathemeh Yari
  • Arezou Rezaei
  • Alireza Razavi
  • Mohammad Reza Ebrahimkhani
  • Mohsen Hamedani
  • Mohammad Pezeshki
  • Mohammad Reza Pourmand
  • Alireza Salek Moghadam
  • Mohammad Mehdi Amiri
  • Amir Hassan Zarnani
  • Saeed Hashemi
  • Z Niazzadeh Najafi
  • Ladan Teimoori-Toolabi
  • Ar Shahverdi
  • Fatemeh Ahadi
  • M Amini
  • Arash Bahremand
  • Mohammad Reza Rasouli
  • Ali Akbar Fallahi
  • Fatemeh Noorbakhsh
  • Faranak Salman Nouri
  • Kazem Mousavizadeh
  • Mohammad Seyedabadi
  • Antonio Caldarelli
  • Jean Eric Ghia
  • Atefeh Taheri Borougeni
  • Pooria Mansoori
  • Zohre Zarei Ghane
  • Maliheh Paknejad
  • Mansooreh Movahedian
  • Hossein Mirmiranpour
  • Siavash Gerayesh Nejad
  • Parvin Pasalar
  • Mehdi Shafiee Ardestani
  • Omid Sabzevari
  • Ahmad Reza Gohari
  • Hamid Reza Shahverdi
  • Sussan Kaboudanian Ardestani
  • Zahra Tavakoli
  • Ahmad Zavaran Hosseini
  • Anoshirvan Kazemnejad
  • Parvin Mansouri
  • Behtash Ghazi Nezami
  • Seyedmehdi Payabvash
  • Zahra Jahanshiri
  • Mohsen Nemat Gorgani
  • Seyed Mohammad Tavangar
  • Mohammad Ansari
  • Artemissia Phoebe Nifli
  • Azadeh Nasseh
  • Vassilia Ismini Alexaki
  • Fatemeh Hadji-Ghasemi
  • Rosanna Di Paola
  • Kamran Alimoghadam
  • Hossein Vatanpour
  • Mohammad Sedaghat
  • Kamiar Zomorodian

Detail Information

Publications29

  1. ncbi request reprint Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters
    Mohammad Reza Khorramizadeh
    School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
    Int J Urol 12:637-43. 2005
    ..Prostate cancer is the most common malignancy affecting men and is a major cause of cancer death. There are increasing data on novel tumor markers, such as gelatinase A, which play a key role in tissue invasion and metastasis...
  2. pmc Fabrication of docetaxel surfaced Fe3O4 magnetite nanoparticles and their cytotoxicity on 4 T1 breast cancer cells
    Mh Yazdi
    Department of Pharmaceutical Biotechnology and Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Daru 20:15. 2012
    ..abstract:..
  3. ncbi request reprint Interaction of CpG-oligodeoxynucleotides with Toll like receptor 9 induces apoptosis and modulates metaloproteinase-2 activity in human intestinal epithelium
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Medical Sciences, University of Tehran, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:107-14. 2007
    ..The direct CpG-ODN and TLR-9 interactions in HT-29 cells could provide new approaches in malignant tumor therapeutic strategies...
  4. ncbi request reprint Suppression of telomerase activity by pyrimethamine: implication to cancer
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Medical Sciences University of Tehran, P O Box 14155 6446, Tehran, Iran
    Iran Biomed J 11:223-8. 2007
    ..We design this study to evaluate its anti-tumoral effect on a model of cell line...
  5. ncbi request reprint Dermal Wound Fibroblasts and Matrix Metaloproteinases (MMPs): Their Possible Role in Allergic Contact Dermatitis
    Mohammad Reza Khorramizadeh
    Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 3:7-11. 2004
    ..In particular, MMP-2 is postulated to be an aim for further gene therapy protocols...
  6. ncbi request reprint Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase
    Farshid Saadat
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Med Sci Monit 11:BR253-7. 2005
    ..This study was undertaken to determine the effect of dexamethasone on apoptosis and matrix metalloproteinase 2 (MMP-2) activity compared with two nonsteroidal anti-inflammatory drugs (NSAIDs), piroxicam and diclofenac...
  7. doi request reprint Anionic linear-globular dendrimers: biocompatible hybrid materials with potential uses in nanomedicine
    Mohammad Shafiee Alavidjeh
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    J Mater Sci Mater Med 21:1121-33. 2010
    ..5 mg/ml. Therefore, the potentiality for these structures to be employed in the different and numerous realms of nanomedicine will be very great...
  8. doi request reprint The in vivo antitumor activity of LHRH targeted methotrexate-human serum albumin nanoparticles in 4T1 tumor-bearing Balb/c mice
    Azade Taheri
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Int J Pharm 431:183-9. 2012
    ..7% of the initial tumor volume 7 days after the treatment. LHRH targeted MTX-HSA NPs could significantly extend the survival time of tumor bearing mice compared with the non-targeted MTX-HSA NPs and free MTX formulations...
  9. ncbi request reprint Matrix metalloproteinase 2 secretion in WEHI 164 fibrosarcoma cells is nitric oxide-related and modified by morphine
    Ahmad Shariftabrizi
    Department of Pathobiology, Tehran University of Medical Sciences, Iran
    Eur J Pharmacol 530:33-9. 2006
    ..We conclude that, as morphine is able to decrease metalloproteinase activity via the NO/NOS system, it may have a place in the treatment of several sarcomas including fibrosarcoma...
  10. ncbi request reprint Chemoprevention by pyrimethamine
    Farshid Saadat
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Immunopharmacol Immunotoxicol 27:233-40. 2005
    ..1, 1, and 10 microg/ml) was 3.30%, 9.42%, and 11.32%, respectively. Our data suggest that pyrimethamine enables suppression of MMP-2 activity and induces apoptosis that could be assumed for chemoprevention therapy...
  11. ncbi request reprint Inhibitory effect of Aspergillus fumigatus extract on matrix metalloproteinases expression
    Farshid Saadat
    Division of Biotechnology, Department of Pathobiology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, P O Box 14155 6446, Tehran, Iran
    Mycopathologia 158:33-7. 2004
    ..Matrix metalloproteinases (MMPs) play a role in several physiologic and pathologic events. There are some evidence indicating the involvement of MMPs in the pathophysiology of fungal infections...
  12. ncbi request reprint Effect of pyrimethamine in experimental rheumatoid arthritis
    Farshid Saadat
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Med Sci Monit 11:BR293-9. 2005
    ..Recent evidence has shown that the antimalarials are useful drugs in the treatment of various rheumatic diseases. The present study was designed to test the therapeutic effect of pyrimethamine (PYR) in collagen-induced arthritis (CIA)...
  13. ncbi request reprint Effect of toll-like receptor 3 agonists on the functionality and metastatic properties of breast cancer cell model
    Nastaran Alizadeh
    Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 12:161-7. 2013
    ..The antimetastatic effect of direct poly (A:U) and TLR3 interactions in MDA-MB-231 cells could provide new approaches in malignant tumor therapeutic strategy...
  14. doi request reprint Sildenafil attenuates TNBS-induced colitis in rats: possible involvement of cGMP and KATP channels
    Gohar Fakhfouri
    Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Fundam Clin Pharmacol 26:190-3. 2012
    ..Sildenafil significantly attenuated colonic injury markers. These effects were reversed by the addition of glibenclamide or ODQ, indicating the involvement of ATP-sensitive potassium channels (KATP) and cGMP, respectively...
  15. pmc Anionic linear-globular dendrimer-cis-platinum (II) conjugates promote cytotoxicity in vitro against different cancer cell lines
    Ismaeil Haririan
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Int J Nanomedicine 5:63-75. 2010
    ..In conclusion, these conjugates with such high potency and minimum hemolysis would be suitable candidates for use against these cancerous cell lines as efficient and novel antitumor agents...
  16. doi request reprint Biosynthesis and recovery of selenium nanoparticles and the effects on matrix metalloproteinase-2 expression
    Mojtaba Shakibaie
    Department of Pharmaceutical Biotechnology and Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Biotechnol Appl Biochem 56:7-15. 2010
    ..Biogenic Se NPs showed a moderately inhibitory effect on MMP-2 expression...
  17. doi request reprint Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin
    Reza Rahimian
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Brain Res 1417:1-8. 2011
    ..Our investigation shows that tropisetron targets calcineurin in a receptor-independent fashion. Tropisetron-induced CB(1) receptor up-regulation might underlie many pharmacological aspects of tropisetron unrelated to anti-emesis...
  18. ncbi request reprint Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells
    Ahmad Shariftabrizi
    Hematology, Oncology and BMTResearch Center, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Mol Cell Biochem 273:109-16. 2005
    ..The level of activity of the telomerase has been shown to correlate with the degree of invasiveness in several tumor types. In addition, cellular redox state is believed to regulate the secretion of matrix metalloproteinase-2 (MMP-2)...
  19. ncbi request reprint In vitro assessment of bee venom effects on matrix metalloproteinase activity and interferon production
    Mohsen Hamedani
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 4:9-14. 2005
    ..In contrast, its inhibitory effect was seen at high concentrations.It is concluded that, honeybee venom affects on MMP-2 activity and interferon beta production as well as cell proliferation in a time and dose-dependent manner...
  20. ncbi request reprint Down-Regulation of sidB Gene by Use of RNA Interference in Aspergillus nidulans
    Hamid Eslami
    Dept of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Iran Biomed J 18:55-9. 2014
    ..Conclusion: Usage of RNAi as a kind of post-transcriptional gene silencing methods is a promising approach for designing new antifungal agents and discovering new drug delivery systems. ..
  21. pmc Intermittent feeding attenuates clinical course of experimental autoimmune encephalomyelitis in C57BL/6 mice
    Laya Kafami
    Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Avicenna J Med Biotechnol 2:47-52. 2010
    ..The results of this study suggest possible role of intermittent feeding in the treatment of Multiple Sclerosis patients...
  22. pmc Use of biotin targeted methotrexate-human serum albumin conjugated nanoparticles to enhance methotrexate antitumor efficacy
    Azade Taheri
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Int J Nanomedicine 6:1863-74. 2011
    ..7%. Mice treated with biotin targeted MTX-HSA NPs showed slight body weight loss (8%) 21 days after treatment, whereas non-targeted MTX-HSA NPs treatment at the same dose caused a body weight loss of 27.05% ± 3.1%...
  23. pmc Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model
    Massih Bahar
    Department of Clinical Biochemistry, Tehran University of Medical Sciences, Faculty of Medicine, Tehran, Iran
    Nutr J 9:62. 2010
    ..Coenzyme Q(10) beneficial effects on cancer are still in controversy but there are indications of Coenzyme Q(10) complementing effect on tamoxifen receiving breast cancer patients...
  24. ncbi request reprint Lithium chloride protects PC12 pheochromocytoma cell line from morphine-induced apoptosis
    Mousa Sahebgharani
    Department of Pharmacology, School of Medicine, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 11:639-48. 2008
    ..Furthermore, there are some reports on the apoptotic effect of morphine on neural cells. In the present study, the effect of morphine and lithium on apoptosis in PC12 cell line (as a model of neural cells) was examined...
  25. ncbi request reprint The effects of N-acetylcysteine on the expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in hepatic fibrosis in bile duct ligated rats
    Arezou Rezaei
    Institute of Biochemistry and Biophysics, Tehran University, Tehran, Iran
    Hepatol Res 38:1252-63. 2008
    ..In addition, administration of N-acetylcysteine was associated with downregulation of the expression of tissue inhibitor of matrix metalloproteinase-2 and amelioration of oxidative stress in the liver of bile duct ligated rats...
  26. doi request reprint Expression of HLA-G in the skin of patients with pemphigus vulgaris
    Fathemeh Yari
    Blood Transfusion Organization, Research Center, Tehran, Iran
    Iran J Allergy Asthma Immunol 7:7-12. 2008
    ..These observations further support suggestions in the literature regarding the role of HLA-G in induction of tolerance in autoimmune individuals...
  27. pmc Green Synthesis of Small Silver Nanoparticles Using Geraniol and Its Cytotoxicity against Fibrosarcoma-Wehi 164
    Mona Safaepour
    Department of Pharmaceutical Biotechnology and Biotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    Avicenna J Med Biotechnol 1:111-5. 2009
    ..The concentration necessary to produce 50% cell death was 2.6 µg/ml for this silver nanoparticles preapared with geraniol...
  28. pmc Down-regulation of the ALS3 gene as a consequent effect of RNA-mediated silencing of the EFG1 gene in Candida albicans
    Maryam Moazeni
    Div of Molecular Biology, Dept of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Iran Biomed J 16:172-8. 2012
    ..In this study, the EFG1 gene was knocked down by using synthetic siRNA in C. albicans and the regulation in ALS3 as one of the Efg1-dependent genes was investigated...
  29. ncbi request reprint Chemopreventive effect of M2000, a new anti-inflammatory agent
    Abbas Mirshafiey
    Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Med Sci Monit 10:PI105-9. 2004
    ..This study was undertaken to explore the role of a newly designed NSAID, M2000 (C6H10O7), as an anti-inflammatory drug in chemoprevention therapy under in vitro conditions...