Mohammad Hossein Ghahremani
Affiliation: Tehran University of Medical Sciences
Akbari Nakhjavani S, Khalilzadeh B, Samadi Pakchin P, Saber R, Ghahremani M, Omidi Y. A highly sensitive and reliable detection of CA15-3 in patient plasma with electrochemical biosensor labeled with magnetic beads. Biosens Bioelectron. 2018;122:8-15 pubmed publisher
..Based on our findings, the engineered immunosensor is proposed as a robust diagnostic tool for the clinical determination of CA 15-3 and other cancer biomarkers. ..
Neyazi N, Motevaseli E, Khorramizadeh M, Mohammadi Farsani T, Nouri Z, Nasli Esfahani E, et al
. Inhibition of Insulin Degrading Enzyme and Insulin Degradation by UV-Killed Lactobacillus acidophilus. Med Sci (Basel). 2018;6: pubmed publisher
..Also, reduction in IDE activity was not statistically considerable when compared to IDE expression. Insulin degradation was increased by CFS but decreased by UV-killed L. acidophilus (ATCC 314). ..
Rahimi H, Dehpour A, Mehr S, Sharifzadeh M, Ghahremani M, Razmi A, et al
. Lithium attenuates cannabinoid-induced dependence in the animal model: involvement of phosphorylated ERK1/2 and GSK-3Î² signaling pathways. Acta Med Iran. 2014;52:656-63 pubmed
..In conclusion, Li neuroprotectionwith regard to cannabinoid abstinence may occur through the regulation of the p-ERK1/2 cascade inconsequent of p-GSK-3Î² signaling pathways in rats. ..
Yazdian S, Fahham N, Ghahremani M, Afzali M, Farsandaj N, Vatankhah M, et al
. Evaluation of the expression of P-glycoprotein in propoxur-resistant Caco-2 cells. Acta Med Iran. 2014;52:728-33 pubmed
..This study indicates that the resistance to propoxur may not be related to P-glycoprotein expression directly, since P-glycoprotein expression has decreased in these cells. ..
Afzali M, Ghaeli P, Khanavi M, Parsa M, Montazeri H, Ghahremani M, et al
. Non-addictive opium alkaloids selectively induce apoptosis in cancer cells compared to normal cells. Daru. 2015;23:16 pubmed publisher
..This experiment suggests that noscapine and papaverine may be of use in cancer treatment due to their specific cytotoxicity and genotoxicity. However, further in vivo studies are needed to confirm its usefulness in cancer treatment. ..
Montazeri H, Bouzari S, Azadmanesh K, Ostad S, Ghahremani M. Overexpression of Cyclin E and its Low Molecular Weight Isoforms Cooperate with Loss of p53 in Promoting Oncogenic Properties of MCF-7 Breast Cancer Cells. Asian Pac J Cancer Prev. 2015;16:7575-82 pubmed
..Taken together these studies suggest that overexpression of LMW-Es in collaboration with p53 loss results in altered growth properties of MCF-7 cells, enhancing the oncogenic activity of these ER positive breast cancer cells. ..
Parsa M, Ostad S, Moogahi S, Bayat M, Ghahremani M. The effect of benzo[?]pyrene on expression and signaling cross talk of aryl hydrocarbon receptor and NFATc1 in mouse lung tissue. Toxicol Ind Health. 2016;32:1246-53 pubmed publisher
..The results from this study point toward the molecular interactions of AhR and NFATc1 activation in lung tissue and the benefit of CsA treatment in B[?]P-induced lung damage. ..
Sharif S, Ghahremani M, Soleimani M. Delivery of Exogenous miR-124 to Glioblastoma Multiform Cells by Wharton's Jelly Mesenchymal Stem Cells Decreases Cell Proliferation and Migration, and Confers Chemosensitivity. Stem Cell Rev. 2018;14:236-246 pubmed publisher
..These results suggest that the use of exogenous miRNA delivery with the derived exosomes from WJ-MSCs may provide a novel approach for miRNA replacement therapy in GBM cancers. ..
Aliomrani M, Sahraian M, Shirkhanloo H, Sharifzadeh M, Khoshayand M, Ghahremani M. Correlation between heavy metal exposure and GSTM1 polymorphism in Iranian multiple sclerosis patients. Neurol Sci. 2017;38:1271-1278 pubmed publisher
..It confirms that the long-term prognosis in MS and patient's disability are influenced by their ability to remove the toxic products and perhaps to decrease oxidative stress. ..