Alireza Esteghamati

Summary

Affiliation: Tehran University of Medical Sciences
Country: Iran

Publications

  1. ncbi request reprint Risk of coronary heart disease associated with metabolic syndrome and its individual components in Iranian subjects: A matched cohort study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran Electronic address
    J Clin Lipidol 8:279-86. 2014
  2. doi request reprint Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005-2011
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Electronic address
    Diabetes Res Clin Pract 103:319-27. 2014
  3. ncbi request reprint The inverse relation of CA-125 to diabetes, metabolic syndrome, and associated clinical variables
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 11:256-61. 2013
  4. ncbi request reprint Accuracy of anthropometric parameters in identification of high-risk patients predicted with cardiovascular risk models
    Alireza Esteghamati
    Department of Endocrinology and Metabolism, Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Am J Med Sci 346:26-31. 2013
  5. ncbi request reprint Comparison of osteoprotegerin and vascular endothelial growth factor in normoalbuminuric Type 1 diabetic and control subjects
    A Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    J Endocrinol Invest 36:474-7. 2013
  6. doi request reprint Gender-dependent effects of metformin on vaspin and adiponectin in type 2 diabetes patients: a randomized clinical trial
    A Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Horm Metab Res 45:319-25. 2013
  7. doi request reprint Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Regul Pept 182:1-6. 2013
  8. doi request reprint Effects of metformin on markers of oxidative stress and antioxidant reserve in patients with newly diagnosed type 2 diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Nutr 32:179-85. 2013
  9. ncbi request reprint Comparing abilities of different lipid measures in diagnosis of insulin resistance: a Survey of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 10:63-9. 2012
  10. doi request reprint Patterns of fruit and vegetable consumption among Iranian adults: a SuRFNCD-2007 study
    Alireza Esteghamati
    School of Medicine, Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Br J Nutr 108:177-81. 2012

Collaborators

Detail Information

Publications80

  1. ncbi request reprint Risk of coronary heart disease associated with metabolic syndrome and its individual components in Iranian subjects: A matched cohort study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran Electronic address
    J Clin Lipidol 8:279-86. 2014
    ..Moreover, we aimed to define the most hazardous MetS components...
  2. doi request reprint Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005-2011
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Electronic address
    Diabetes Res Clin Pract 103:319-27. 2014
    ..To estimate the prevalence and trends of diabetes mellitus (DM) and impaired fasting glucose (IFG), 2005-2011, and to determine the contribution of obesity to DM prevalence...
  3. ncbi request reprint The inverse relation of CA-125 to diabetes, metabolic syndrome, and associated clinical variables
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 11:256-61. 2013
    ..We aimed to evaluate the association of carbohydrate antigen 125 (CA-125; also known as cancer antigen 125) with various anthropometric and metabolic measures and also with diabetes and metabolic syndrome...
  4. ncbi request reprint Accuracy of anthropometric parameters in identification of high-risk patients predicted with cardiovascular risk models
    Alireza Esteghamati
    Department of Endocrinology and Metabolism, Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Am J Med Sci 346:26-31. 2013
    ..Early detection of the patients' high risk for developing cardiovascular disease (CVD) is a primary care priority. Simple-to-use screening tools derived from anthropometric parameters and obesity-related indices could serve this purpose...
  5. ncbi request reprint Comparison of osteoprotegerin and vascular endothelial growth factor in normoalbuminuric Type 1 diabetic and control subjects
    A Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    J Endocrinol Invest 36:474-7. 2013
    ..The aim of the current study was to evaluate the association of osteoprotegerin and vascular endothelial growth factor (VEGF) with glycemic indices and diabetes status...
  6. doi request reprint Gender-dependent effects of metformin on vaspin and adiponectin in type 2 diabetes patients: a randomized clinical trial
    A Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Horm Metab Res 45:319-25. 2013
    ..012 and 0.579 for women and men, respectively). Our findings suggest that metformin therapy reduces vaspin concentration in a gender-specific manner. Metformin exerts little benefit in increasing adiponectin levels in diabetes patients...
  7. doi request reprint Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Regul Pept 182:1-6. 2013
    ..To assess the effects of two commonly used oral hypoglycemic medications metformin and pioglitazone on serum concentrations of omentin and leptin in patients with newly diagnosed type 2 diabetes...
  8. doi request reprint Effects of metformin on markers of oxidative stress and antioxidant reserve in patients with newly diagnosed type 2 diabetes: a randomized clinical trial
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Nutr 32:179-85. 2013
    ..Effects of metformin on markers of oxidative stress, antioxidant reserve, and HDL-c associated antioxidant enzymes were investigated...
  9. ncbi request reprint Comparing abilities of different lipid measures in diagnosis of insulin resistance: a Survey of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) study
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 10:63-9. 2012
    ..Dyslipidemia is a distinguishing characteristic of subjects with insulin resistance. Our aim was to determine the predictive abilities and appropriate cutoffs of different lipid variables for insulin resistance...
  10. doi request reprint Patterns of fruit and vegetable consumption among Iranian adults: a SuRFNCD-2007 study
    Alireza Esteghamati
    School of Medicine, Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Br J Nutr 108:177-81. 2012
    ..A high prevalence of low F&V consumption in the Iranian adult population was documented. These findings may guide health policy makers in developing specific plans to encourage adequate F&V intake...
  11. doi request reprint Apolipoproteins a-I and B as components of metabolic syndrome with respect to diabetes status: a factor analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 10:280-5. 2012
    ..The aim of the current study was to elucidate the clustering pattern of metabolic syndrome components along with apolipoproteins (Apo) A-I and B in diabetic and nondiabetic subjects...
  12. doi request reprint The value of visfatin in the prediction of metabolic syndrome: a multi-factorial analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Cardiovasc Transl Res 5:541-6. 2012
    ..These findings may contribute to our current knowledge about visfatin in metabolic syndrome...
  13. pmc Physical inactivity is correlated with levels of quantitative C-reactive protein in serum, independent of obesity: results of the national surveillance of risk factors of non-communicable diseases in Iran
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Health Popul Nutr 30:66-72. 2012
    ..Physical activity (of both moderate and vigorous intensity) is inversely associated with the quantitative CRP levels in serum, independent of diabetes and body adiposity...
  14. doi request reprint HOMA-estimated insulin resistance is associated with hypertension in Iranian diabetic and non-diabetic subjects
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences University of Tehran, Tehran, Iran
    Clin Exp Hypertens 30:297-307. 2008
    ..102, CI 95% = 1.009-1.203, p < 0.05 and odds ratio = 1.328, CI 95% = 1.116-1.580, p < 0.01, respectively). In conclusion, this study showed that IR is associated with HTN in Iranian diabetic and non-diabetic subjects...
  15. ncbi request reprint Prevalence of diabetes and impaired fasting glucose in the adult population of Iran: National Survey of Risk Factors for Non-Communicable Diseases of Iran
    Alireza Esteghamati
    Endocrine Research Center, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Care 31:96-8. 2008
    ..With this article, we document a dramatically high prevalence of diabetes in Iran...
  16. pmc Metabolic syndrome is linked to a mild elevation in liver aminotransferases in diabetic patients with undetectable non-alcoholic fatty liver disease by ultrasound
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetol Metab Syndr 2:65. 2010
    ..In this study, we aimed to assess the relationship between circulating liver enzymes and MetS in a relatively large sample of patients with diabetes...
  17. ncbi request reprint Secular trends of obesity in Iran between 1999 and 2007: National Surveys of Risk Factors of Non-communicable Diseases
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 8:209-13. 2010
    ..There is no solid evidence on the recent trends of obesity in Iran. In this study we present the secular trends of overweight and obesity among Iranian adults (25-64 years old) within an 8-year period (1999-2007)...
  18. ncbi request reprint Association of serum cortisol levels with parameters of metabolic syndrome in men and women
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Clin Invest Med 34:E131-7. 2011
    ..The purpose of this study was to compare serum cortisol levels, and its correlation with serum leptin levels, between men and women with and without metabolic syndrome...
  19. pmc Optimal cut-off of homeostasis model assessment of insulin resistance (HOMA-IR) for the diagnosis of metabolic syndrome: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Nutr Metab (Lond) 7:26. 2010
    ..The aim of the present study is to establish the optimal cut-off at the national level in the Iranian population with and without diabetes...
  20. doi request reprint Physical activity is correlated with serum leptin independent of obesity: results of the national surveillance of risk factors of noncommunicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, PO Box 13145 784, Tehran 14107 33141, Iran
    Metabolism 59:1730-5. 2010
    ..In conclusion, our results demonstrated an inverse association between leptin concentrations and PA independent of age, sex, smoking, and body adiposity. Our results point to the regulatory effects of PA on serum leptin...
  21. doi request reprint Clustering of leptin and physical activity with components of metabolic syndrome in Iranian population: an exploratory factor analysis
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Endocrine 38:206-13. 2010
    ..Further, this study suggests that physical activity influences MetS components via modulation of the main underlying pathophysiologic pathway of this syndrome...
  22. doi request reprint Insulin resistance is independently associated with liver aminotransferases in diabetic patients without ultrasound signs of nonalcoholic fatty liver disease
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 9:111-7. 2011
    ..The aim of this study was to assess the association between elevated liver enzymes and insulin resistance in diabetic subjects without ultrasound signs of nonalcoholic fatty liver disease (NAFLD) (i.e., with less than 30% steatosis)...
  23. doi request reprint Association between physical activity and insulin resistance in Iranian adults: National Surveillance of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences PO Box 13145 784, Tehran, Iran
    Prev Med 49:402-6. 2009
    ..Insulin resistance is an underlying mechanism of metabolic syndrome. We attempted to determine the association between physical activity and insulin resistance in Iranian adults...
  24. doi request reprint Trends of diabetes according to body mass index levels in Iran: results of the national Surveys of Risk Factors of Non-Communicable Diseases (1999-2007)
    A Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabet Med 27:1233-40. 2010
    ..The prevalence of diabetes is increasing dramatically worldwide. Less is known about whether this trend is similar among obese and lean individuals...
  25. doi request reprint Metabolic syndrome and insulin resistance significantly correlate with body mass index
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences University of Tehran, Tehran, Iran
    Arch Med Res 39:803-8. 2008
    ..Metabolic syndrome (MetS) is a cluster of metabolic risk factors for cardiovascular disease. This study aimed to compare the prevalence of MetS and its components in different degrees of obesity in Iranian subjects...
  26. doi request reprint Serum visfatin is associated with type 2 diabetes mellitus independent of insulin resistance and obesity
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Res Clin Pract 91:154-8. 2011
    ..The aim of this study was to evaluate the association of serum visfatin, adiponectin and leptin with 2 diabetes mellitus (T2DM) in the context of the role of obesity or insulin resistance, which is not well understood...
  27. doi request reprint Optimal threshold of homeostasis model assessment for insulin resistance in an Iranian population: the implication of metabolic syndrome to detect insulin resistance
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Res Clin Pract 84:279-87. 2009
    ..In this study, the cut point of HOMA to detect IR was lower than other populations. IR is an unyielding correlate of MetS; but definitions of MetS are insensitive measures of IR in our population...
  28. doi request reprint Association of serum leptin levels with homeostasis model assessment-estimated insulin resistance and metabolic syndrome: the key role of central obesity
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 7:447-52. 2009
    ..This study evaluated the relationship between leptin, metabolic syndrome, and insulin resistance in an Iranian population and further investigated whether this relationship is confounded by obesity or central obesity...
  29. doi request reprint The economic costs of diabetes: a population-based study in Tehran, Iran
    A Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetologia 52:1520-7. 2009
    ..The aim of the study was to determine the annual healthcare expenditures of an individual with diabetes in Tehran, between March 2004 and March 2005...
  30. doi request reprint Metabolic syndrome is independently associated with microalbuminuria in type 2 diabetes
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Acta Diabetol 47:125-30. 2010
    ..01). In multivariate regression, MetS was the strongest correlate of microalbuminuria (OR = 3.31, 95% CI = 1.91-5.75; P < 0.01). In conclusion, MetS is independently associated with microalbuminuria in type 2 diabetes...
  31. pmc Third national Surveillance of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) in Iran: methods and results on prevalence of diabetes, hypertension, obesity, central obesity, and dyslipidemia
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    BMC Public Health 9:167. 2009
    ..This trend seems to be faster in developing countries of the Middle East. In this study, we presented the latest prevalence rates of a number of important non-communicable diseases and their risk factors in the Iranian population...
  32. doi request reprint Leptin cut-off values for determination of metabolic syndrome: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Endocrine 40:117-23. 2011
    ..The diagnostic accuracy of these values in identifying MetS was similar to that of insulin resistance. Therefore, leptin is comparable to insulin resistance in identifying MetS and can be used as single predictor of MetS...
  33. doi request reprint Contribution of serum leptin to metabolic syndrome in obese and nonobese subjects
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Arch Med Res 42:244-51. 2011
    ..Moreover, the contribution of obesity to this relationship is not well understood. This study aimed to evaluate the association between leptin concentrations with MetS in obese and nonobese subjects...
  34. pmc Clustering of metabolic syndrome components in a Middle Eastern diabetic and non-diabetic population
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Diabetol Metab Syndr 2:36. 2010
    ..In this study, we aimed to elucidate the factors underlying the clustering of MetS components in diabetic and non-diabetic individuals...
  35. doi request reprint Association between physical activity and metabolic syndrome in Iranian adults: national surveillance of risk factors of noncommunicable diseases (SuRFNCD-2007)
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Metabolism 58:1347-55. 2009
    ..28-fold with every 30-min/d reduction in vigorous-intensity activity (95% confidence interval = 1.15-1.42, P < .001). The results of the present study should be considered for future public health programs in Iran...
  36. doi request reprint Association of plasma leptin levels and insulin resistance in diabetic women: a cross-sectional analysis in an Iranian population with different results in men and women
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Gynecol Endocrinol 27:14-9. 2011
    ..The objective of this study was to assess the association of serum leptin levels with insulin resistance (IR), metabolic syndrome (MetS), lipid levels, and glucose control in an Iranian type 2 diabetic population...
  37. ncbi request reprint Genetic susceptibility to Graves' ophthalmopathy: The role of polymorphisms in anti-inflammatory cytokine genes
    Omid Khalilzadeh
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Ophthalmic Genet 31:215-20. 2010
    ..In this study, we investigated the association between 8 polymorphisms within the mentioned cytokines and GO...
  38. ncbi request reprint Association between oxidant/antioxidant markers and proteinuria in type 2 diabetes: results in 142 patients
    Armin Rashidi
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Nephrol 22:733-8. 2009
    ..The relationship between oxidant/antioxidant markers and proteinuria in type 2 diabetes is not clear, partly because of the potentially confounding effect of renal function which tends to become impaired during the course of diabetes...
  39. doi request reprint Comparative effects of pioglitazone and metformin on oxidative stress markers in newly diagnosed type 2 diabetes patients: a randomized clinical trial
    Hossein Mirmiranpour
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Electronic address
    J Diabetes Complications 27:501-7. 2013
    ..Recent studies have suggested that pioglitazone exerts anti-oxidant properties which may countervail oxidative stress (OS). We aimed to elucidate the effects of pioglitazone on OS modulation and to compare its effects with metformin...
  40. doi request reprint Appropriate BMI cut-off values for identification of metabolic risk factors: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)
    Ali Zandieh
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Ann Hum Biol 39:484-9. 2012
    ..To determine the appropriate threshold of body mass index (BMI) associated with increased risk of cardiovascular diseases in a large representative sample of an Iranian population...
  41. doi request reprint Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves' disease
    Omid Khalilzadeh
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Clin Exp Med 10:123-8. 2010
    ..47 and 0.08, respectively; P < 0.01). In conclusion, this study highlighted the importance of anti-inflammatory cytokine gene polymorphisms in susceptibility to GD...
  42. pmc Pattern of tobacco use among the Iranian adult population: results of the national Survey of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007)
    Alipasha Meysamie
    Department of Community and Preventive Medicine, Faculty of Medicine, Tehran University of Medical Sciences University of Tehran, Tehran, Iran
    Tob Control 19:125-8. 2010
    ..Previous studies report on smoking in Iran but recent national data on tobacco use (including cigarette, water-pipe and pipe) have not been reported...
  43. doi request reprint Vascular endothelial growth factor (VEGF) +405 C/G polymorphism is associated with essential hypertension in a population from Tehran of Iran
    Amir Abbas Hamedian
    Health Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
    Mol Biol Rep 39:6213-8. 2012
    ..200-2.086; P = 0.001). In conclusion, +405 VEGF C/G SNP is associated with EH in patients with diabetes, suggesting presence of G allele and GG or CG genotype confer susceptibility towards EH...
  44. doi request reprint The lost correlation between leptin and CRP in type 2 diabetes
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 24:53-9. 2013
    ..584, p<0.01). Statin treatment did not have any significant effect on the results. This is the first report demonstrating the restorative role of metformin on the leptin-CRP correlation in patients with newly diagnosed diabetes...
  45. doi request reprint Serum oxidized-LDL is associated with diabetes duration independent of maintaining optimized levels of LDL-cholesterol
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Lipids 45:321-7. 2010
    ..Our findings highlight that possibly more attention should be focused on markers of oxidative stress in the management of lipids in diabetic patients...
  46. doi request reprint Pretibial myxedema is associated with polymorphism in exon 1 of CTLA-4 gene in patients with Graves' ophthalmopathy
    Omid Khalilzadeh
    Molecular Immunology and Immunogenetics Research Center, Medical Sciences University of Tehran, Tehran, Iran
    Arch Dermatol Res 301:719-23. 2009
    ..In conclusion, the +49G allele is associated with increased risk of PTM in patients with GO. Studies with larger sample sizes are needed to confirm the results of the present study...
  47. doi request reprint Prevalence, awareness, treatment, and risk factors associated with hypertension in the Iranian population: the national survey of risk factors for noncommunicable diseases of Iran
    Alireza Esteghamati
    Endocrine Research Center, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Am J Hypertens 21:620-6. 2008
    ..The prevalence of hypertension in the Middle East is not well defined. We examined the prevalence, awareness, treatment, and control of hypertension in Iran...
  48. ncbi request reprint Correlates of ACE activity in macroalbuminuric type 2 diabetic patients treated with chronic ACE inhibition
    Abdolrahim Nikzamir
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences University of Tehran, Iran
    Nephrol Dial Transplant 23:1274-7. 2008
    ..In conclusion, the D allele is a significant independent correlate of ACE activity in macroalbuminuric type 2 diabetic Iranian patients under long-term ACE inhibition...
  49. doi request reprint Inconsistency in albuminuria predictors in type 2 diabetes: a comparison between neural network and conditional logistic regression
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Transl Res 161:397-405. 2013
    ..Our neural network model complements the current risk factor models to improve the care of patients with diabetes...
  50. doi request reprint Graves' disease and gene polymorphism of TNF-α, IL-2, IL-6, IL-12, and IFN-γ
    Mehdi Anvari
    Molecular Immunology and Immunogenetics Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Endocrine 37:344-8. 2010
    ..Our results support the hypothesis that polymorphism in pro-inflammatory cytokines might be involved in predisposition to GD...
  51. ncbi request reprint Association of macroalbuminuria with oxidized LDL and TGF-beta in type 2 diabetic patients: a case-control study
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Int Urol Nephrol 42:487-92. 2010
    ....
  52. ncbi request reprint HbA1c negatively correlates with LCAT activity in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Imam Khomeini Medical Complex, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Diabetes Res Clin Pract 81:38-41. 2008
    ..The purpose of this study was to determine the independent correlates of LCAT activity in DM2 patients...
  53. doi request reprint Menopause is an independent predictor of metabolic syndrome in Iranian women
    Radina Eshtiaghi
    AJA University of Medical Science, 3th floor, Endocrine Research Center, Emam Reza Hospital 501 AJA, Etemad Zadeh Ave, Fatemi St, Tehran, Iran
    Maturitas 65:262-6. 2010
    ..Postmenopausal status may explain in part the cause of acceleration of CVD with aging. The purpose of this study was to investigate the relation of menopause and metabolic syndrome independent of aging among Iranian women...
  54. ncbi request reprint Gender-specific changes in physical activity pattern in Iran: national surveillance of risk factors of non-communicable diseases (2007-2011)
    Jalil Koohpayehzadeh
    Center for Disease Control, Tehran, Iran
    Int J Public Health 59:231-41. 2014
    ..This study describes the gender-specific pattern of physical activity (PA) in Iran 2011. The 4-year changes in PA levels (domains) are also determined according to the Iran's national surveys conducted on 2007 and 2011...
  55. doi request reprint Treatment with pioglitazone is associated with decreased preprandial ghrelin levels: a randomized clinical trial
    Shervin Taslimi
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Peptides 40:89-92. 2013
    ..The effect of pioglitazone on ghrelin is independent of changes in body weight, body mass index, plasma insulin, insulin resistance, or glucose control...
  56. pmc Albuminuria and its correlates in an Iranian type 2 diabetic population
    Manouchehr Nakhjavani
    Endocrine and Metabolism Research Center, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Lipids Health Dis 7:28. 2008
    ..To study the prevalence and correlates of increased urinary albumin excretion (UAE) in an Iranian type 2 diabetic population...
  57. doi request reprint Diabetes induces gender gap on LCAT levels and activity
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Life Sci 92:51-4. 2013
    ..Here we aimed to study serum LCAT levels and LCAT activity in men and women with type 2 diabetes (T2DM) as well as healthy controls...
  58. pmc Prevalence of diabetes and other cardiovascular risk factors in an Iranian population with acute coronary syndrome
    Alireza Esteghamati
    Faculty of Medicine, Tehran University of Medical Sciences, Keshavarz Blvd, Tehran, Iran
    Cardiovasc Diabetol 5:15. 2006
    ....
  59. ncbi request reprint Graves' ophthalmopathy and gene polymorphisms in interleukin-1alpha, interleukin-1beta, interleukin-1 receptor and interleukin-1 receptor antagonist
    Omid Khalilzadeh
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran, Iran
    Clin Experiment Ophthalmol 37:614-9. 2009
    ..This study aimed to investigate the association of GO with single-nucleotide polymorphisms (SNPs) in the IL-1 family (IL-1alpha, IL-1beta, IL-1 receptor [IL-1R] and IL-1 receptor antagonist [IL-1RA])...
  60. doi request reprint Association of oxidized low-density lipoprotein and transforming growth factor-beta in type 2 diabetic patients: a cross-sectional study
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Transl Res 153:86-90. 2009
    ..308, P = 0.007). In conclusion, this study demonstrated that ox-LDL is significantly correlated to TGF-beta in type 2 diabetic patients...
  61. pmc Gender difference in albuminuria and ischemic heart disease in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, PO Box 13145 784, Tehran, Iran
    Clin Med Res 10:51-6. 2012
    ..We questioned whether gender influences the albuminuria-ischemic heart disease relationship in patients with type 2 diabetes...
  62. ncbi request reprint The relationship between the insertion/deletion polymorphism of the ACE gene and hypertension in Iranian patients with type 2 diabetes
    Manouchehr Nakhjavani
    Endocrine and Metabolism Research Center, Vali Asr Hospital, and Department of Biochemistry, School of Medicine, Medical Sciences, University of Tehran, No 12, Aramesh Alley, Mellat Park, Tehran, Iran
    Nephrol Dial Transplant 22:2549-53. 2007
    ..The aim of this study was to evaluate for the first time the possible association between I/D polymorphism and hypertension in an Iranian diabetic adult population...
  63. doi request reprint Serum lipoprotein(a) levels are greater in female than male patients with type-2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Lipids 46:349-56. 2011
    ..The increase in women was independent of menopause. The level of serum Lp(a) had no correlation with lipid parameters in men or women...
  64. pmc Increased serum HSP70 levels are associated with the duration of diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, P O Box 13145 784, Tehran, Iran
    Cell Stress Chaperones 15:959-64. 2010
    ..Higher HSP70 in prolonged diabetes versus newly diagnosed diabetes may be an indicator of metabolic derangement in the course of diabetes...
  65. pmc Serum heat shock protein 70 and oxidized LDL in patients with type 2 diabetes: does sex matter?
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Cell Stress Chaperones 16:195-201. 2011
    ..We suggest that diabetes induces an immune response and impairs cellular defense mechanisms against oxidative stress more commonly in women with type 2 diabetes than in men...
  66. doi request reprint Metformin restores the correlation between serum-oxidized LDL and leptin levels in type 2 diabetic patients
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Redox Rep 16:193-200. 2011
    ..We also studied the effect of metformin therapy on the correlation between serum ox-LDL and leptin levels in patients with newly diagnosed diabetes...
  67. doi request reprint Oxidized low-density lipoprotein is negatively correlated with lecithin-cholesterol acyltransferase activity in type 2 diabetes mellitus
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Iran
    Am J Med Sci 341:92-5. 2011
    ....
  68. doi request reprint Insulin resistance and breast carcinogenesis: a cross-sectional study among Iranian women with breast mass
    Mehrshad Abbasi
    Endocrinology and Metabolism Research Center, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Metab Syndr Relat Disord 8:411-6. 2010
    ..001, partial eta squared = 0.11]. We conclude that the noted linkage between insulin resistance and breast cancer may indicate an underlying pathology of mammary carcinogenesis...
  69. doi request reprint Association of CTLA-4 gene polymorphism with Graves' disease and ophthalmopathy in Iranian patients
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center, Vali Asr Hospital, Medical Sciences, University of Tehran, Tehran, Iran
    Eur J Intern Med 20:424-8. 2009
    ..This study aimed to investigate the association of Graves' disease and Graves' ophthalmopathy with polymorphisms at position +49 in exon 1 and positions -318 and -1147 in the promoter region of CTLA-4 gene in Iranian patients...
  70. doi request reprint Epidemiology and risk factors of the cardiometabolic syndrome in the Middle East
    Haleh Ashraf
    Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran
    Expert Rev Cardiovasc Ther 9:309-20. 2011
    ..We explore the results of our national surveys as successful examples along this path...
  71. doi request reprint Waist circumference cut-off points for the diagnosis of metabolic syndrome in Iranian adults
    Alireza Esteghamati
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Diabetes Res Clin Pract 82:104-7. 2008
    ..The purpose of this study was to determine optimal cut-off points for the diagnosis of MetS in Iran...
  72. doi request reprint Association of +45(T/G) and +276(G/T) polymorphisms in the adiponectin gene with coronary artery disease in a population of Iranian patients with type 2 diabetes
    Alireza Esteghamati
    Endocrine Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Mol Biol Rep 39:3791-7. 2012
    ..Also Haplotype analysis showed that two haplotypes 45T-276T and 45G-276T were associated with a decreased risk of CAD...
  73. doi request reprint The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Gene 498:107-11. 2012
    ..They are both inhibitors of nitric oxide synthase (NOS). The aim of this study was to evaluate the correlation between ADMA and HSP70, in patients with type 2 diabetes with respect to serum levels of C reactive protein (CRP)...
  74. ncbi request reprint Constant magnetic field of 50 mT does not affect weight gain and blood glucose level in BALB/c mice
    Mehrshad Abbasi
    Endocrine Research Center, Vali Asr Hospital, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Med Sci Monit 13:BR151-4. 2007
    ..01- and 0.001-Tesla and weight loss in 0.9-Tesla constant electromagnetic fields. This study aimed to examine the effect of a 0.05-Tesla constant magnetic field on weight gain and blood glucose homeostasis in BALB/c mice...
  75. pmc Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism
    Manouchehr Nakhjavani
    Endocrinology and Metabolism Research Centre EMRC, Vali Asr Hospital, Tehran, Iran
    Br J Clin Pharmacol 68:634-7. 2009
    ..To investigate the effects of spironolactone on serum lipids in women with hirsutism over a 3-month period...
  76. doi request reprint Serum interleukin-1 and interleukin-6 are correlated neither with oxidized low density lipoprotein, nor with low-grade inflammation in patients with type 2 diabetes
    Afsaneh Morteza
    Endocrinology and Metabolism Research Center EMRC, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 22:107-12. 2011
    ..We measured serum high sensitivity CRP (hs-CRP) levels in order to define basal inflammation in patients and controls...
  77. ncbi request reprint The association between urodynamic findings and microvascular complications in patients with long-term type 2 diabetes but without voiding symptoms
    Alireza Esteghamati
    Endocrine Research Center ERC, Vali Asr Hospital, Tehran University of Medical Sciences TUMS, Tehran, Iran
    Diabetes Res Clin Pract 78:42-50. 2007
    ..310; p=0.019). In conclusion, searching for microvascular complications might be used to screen for some components of diabetic cystopathy in its asymptomatic phase...
  78. doi request reprint Amygdalin inhibits angiogenesis in the cultured endothelial cells of diabetic rats
    Hossein Mirmiranpour
    Department of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Indian J Pathol Microbiol 55:211-4. 2012
    ..Angiogenesis contributes to different physiological and pathological conditions. The aim of this study was to investigate for the first time the antiangiogenic effects of amygdalin on the cultured endothelial cells of diabetic rats...
  79. ncbi request reprint The safety and efficacy of biphasic insulin aspart 30 (BIAsp 30) in Iranians with type 2 diabetes: an open-label, non-randomised, multi-centre observational study--the Iran subgroup of the IMPROVE™ study
    Alireza Esteghamati
    Imam Khomeini Hospital, Endocrine and Metabolism research Department, Tehran, Iran
    Endokrynol Pol 61:364-70. 2010
    ..To evaluate the clinical profile of BIAsp 30 (30% soluble insulin aspart, 70% protamine-crystallized insulin aspart) (NovoMix®)30) in type 2 diabetes patients in routine clinical practice in Iran...