Ali Mohammad Alizadeh


Affiliation: Tehran University of Medical Sciences
Country: Iran


  1. Khalighfard S, Alizadeh A, Irani S, Omranipour R. Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patients. Sci Rep. 2018;8:17981 pubmed publisher
    ..It seems that monitoring miRs during treatment might be considered as a respectable diagnostic tool for monitoring of breast cancer patients. ..
  2. Hosseini Kharat M, Zargarian D, Alizadeh A, Karami K, Saeidifar M, Khalighfard S, et al. In vitro and in vivo antiproliferative activity of organo-nickel SCS-pincer complexes on estrogen responsive MCF7 and MC4L2 breast cancer cells. Effects of amine fragment substitutions on BSA binding and cytotoxicity. Dalton Trans. 2018;47:16944-16957 pubmed publisher
    ..In vivo administration of this compound significantly inhibits tumor growth in estrogen-dependent MC4L2 cancer cells in female BALB/c mice. ..
  3. Heydari Z, Rahaie M, Alizadeh A, Agah S, Khalighfard S, Bahmani S. Effects of Lactobacillus acidophilus and Bifidobacterium bifidum Probiotics on the Expression of MicroRNAs 135b, 26b, 18a and 155, and Their Involving Genes in Mice Colon Cancer. Probiotics Antimicrob Proteins. 2018;: pubmed publisher
    ..It seems that Lactobacillus acidophilus and Bifidobacterium bifidum though increasing the expression of the tumor suppressor miRNAs and their target genes and decreasing the oncogenes can improve colon cancer treatment. ..
  4. Khori V, Alizadeh A, Khalighfard S, Heidarian Y, Khodayari H. Oxytocin effects on the inhibition of the NF-?B/miR195 pathway in mice breast cancer. Peptides. 2018;107:54-60 pubmed publisher
    ..These results can exhibit a new therapeutic potential for OT on the down-regulation of the NF-?B and up-regulation of miR-195 and consequently, decrease of the tumor volume and weight in a mouse model of breast cancer. ..
  5. Kavosi A, Hosseini Ghale Noei S, Madani S, Khalighfard S, Khodayari S, Khodayari H, et al. The toxicity and therapeutic effects of single-and multi-wall carbon nanotubes on mice breast cancer. Sci Rep. 2018;8:8375 pubmed publisher
    ..As a result, CNTs especially MWCNT in lower dosages can be used as a promising drug delivery vehicle for targeted therapy of abnormal cells in breast cancer. ..
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    Ranji P, Heydari Z, Alizadeh A. Nanobiotechnological Approaches to Overcome Drug Resistance in Breast Cancer. Curr Cancer Drug Targets. 2015;15:544-62 pubmed
    ..The present paper provides information and suggestions to both basic and clinical researchers to develop new nanobiotechnological methods to improve breast cancer modalities especially in drug resistance. ..
  7. Chamani R, Ranji P, Hadji M, Nahvijou A, Esmati E, Alizadeh A. Application of E75 peptide vaccine in breast cancer patients: A systematic review and meta-analysis. Eur J Pharmacol. 2018;831:87-93 pubmed publisher
    ..Evaluation of the local and systemic toxicity of the E75 peptide vaccine demonstrated the minimal side effects. It seems that the E75 peptide vaccine is safe and effective, and can be used for further randomized clinical trials. ..
  8. Agah S, Alizadeh A, Mosavi M, Ranji P, Khavari Daneshvar H, Ghasemian F, et al. More Protection of Lactobacillus acidophilus Than Bifidobacterium bifidum Probiotics on Azoxymethane-Induced Mouse Colon Cancer. Probiotics Antimicrob Proteins. 2018;: pubmed publisher
    ..acidophilus compared to AOM (P < 0.05). Our study highlighted the more potential effects of L. acidophilus probiotic than B. bifidum on mouse colon cancer. ..
  9. Farhangi B, Alizadeh A, Khodayari H, Khodayari S, Dehghan M, Khori V, et al. Protective effects of dendrosomal curcumin on an animal metastatic breast tumor. Eur J Pharmacol. 2015;758:188-96 pubmed publisher
    ..05). These outcomes indicate that dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products. ..

More Information


  1. request reprint
    Farsinejad S, Rahaie M, Alizadeh A, Mir Derikvand M, Gheisary Z, Nosrati H, et al. Expression of the circulating and the tissue microRNAs after surgery, chemotherapy, and radiotherapy in mice mammary tumor. Tumour Biol. 2016;37:14225-14234 pubmed
    ..It seems that the oncomiRs in the plasma can be an ideal noninvasive candidate biomarker for the early detection of breast cancer and also for following the response of the common therapies. ..
  2. Bagheri F, Khori V, Alizadeh A, Khalighfard S, Khodayari S, Khodayari H. Reactive oxygen species-mediated cardiac-reperfusion injury: Mechanisms and therapies. Life Sci. 2016;165:43-55 pubmed publisher
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    Ranji P, Salmani Kesejini T, Saeedikhoo S, Alizadeh A. Targeting cancer stem cell-specific markers and/or associated signaling pathways for overcoming cancer drug resistance. Tumour Biol. 2016;37:13059-13075 pubmed
    ..This review will focus on the innovative treatment methods such as nano-, immuno-, gene-, and chemotherapy approaches for targeting CSC-specific markers and/or their associated signaling pathways. ..
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    Khori V, Alizadeh A, Gheisary Z, Farsinejad S, Najafi F, Khalighfard S, et al. The effects of low-level laser irradiation on breast tumor in mice and the expression of Let-7a, miR-155, miR-21, miR125, and miR376b. Lasers Med Sci. 2016;31:1775-1782 pubmed
    ..It seems that the non-invasive nature of laser bio-stimulation can make LLLT an attractive alternative therapeutic tool. ..
  5. Mohsenikia M, Farhangi B, Alizadeh A, Khodayari H, Khodayari S, Khori V, et al. Therapeutic effects of dendrosomal solanine on a metastatic breast tumor. Life Sci. 2016;148:260-7 pubmed publisher
    ..The findings suggest that DNS has a more impactful therapeutic effect than solanine on 4 T1-induced breast tumorigenesis via influencing the tissue microenvironment. ..
  6. Khori V, Amani Shalamzari S, Isanejad A, Alizadeh A, Alizadeh S, Khodayari S, et al. Effects of exercise training together with tamoxifen in reducing mammary tumor burden in mice: Possible underlying pathway of miR-21. Eur J Pharmacol. 2015;765:179-87 pubmed publisher
    ..Results showed that interval exercise training may reduce mammary tumor burden in mice through possible underlying pathway of miR-21. ..
  7. Farhanji B, Latifpour M, Alizadeh A, Khodayari H, Khodayari S, Khaniki M, et al. Tumor suppression effects of myoepithelial cells on mice breast cancer. Eur J Pharmacol. 2015;765:171-8 pubmed publisher
    ..05). VEGF and alpha-smooth muscle actin mRNA expression were reduced in treated animals (P<0.05). The present study highlighted the potential tumor suppression effects of MECs on breast cancer in a typical animal model. ..
  8. Isanejad A, Alizadeh A, Amani Shalamzari S, Khodayari H, Khodayari S, Khori V, et al. MicroRNA-206, let-7a and microRNA-21 pathways involved in the anti-angiogenesis effects of the interval exercise training and hormone therapy in breast cancer. Life Sci. 2016;151:30-40 pubmed publisher
    ..Our results showed that miR-21, miR-206 and let-7a pathways may involve in the anti-angiogenesis effects of the interval exercise training with hormone therapy in mice model of breast tumor. ..