Masoud Soleimani

Summary

Affiliation: Tarbiat Modarres University
Country: Iran

Publications

  1. ncbi request reprint Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells
    Samad Nadri
    Stem Cell Department, Stem Cell Technology Co Ltd, Tehran, Iran
    Differentiation 76:223-31. 2008
  2. ncbi request reprint An efficient method for isolation of murine bone marrow mesenchymal stem cells
    Samad Nadri
    Stem Cells and Tissue Engineering Department, Stem Cell Technology, Tehran, Iran
    Int J Dev Biol 51:723-9. 2007
  3. ncbi request reprint Characterization of fibroblast-like cells from the rat olfactory bulb
    Masoud Soleimani
    Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Int J Dev Biol 52:979-84. 2008
  4. ncbi request reprint A microRNA signature associated with chondrogenic lineage commitment
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, 14174 Tehran, Iran
    J Genet 91:171-82. 2012
  5. pmc The High Yield Expansion and Megakaryocytic Differentiation of Human Umbilical Cord Blood CD133(+) Cells
    Mahin Nikougoftar Zarif
    1 Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran 2 Iran Blood Transfusion Organization Research Center, Tehran, Iran
    Cell J 13:173-8. 2011
  6. doi request reprint Unrestricted somatic stem cells as vehicle for nerve growth factor gene transfer
    Hanieh Jalali
    Department of Developmental Biology, Faculty of Biological Science, Kharazmi University, Tehran, Iran
    Neurol Res 35:553-60. 2013
  7. doi request reprint The effects of low-level laser irradiation on differentiation and proliferation of human bone marrow mesenchymal stem cells into neurons and osteoblasts--an in vitro study
    Masoud Soleimani
    Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Lasers Med Sci 27:423-30. 2012
  8. doi request reprint A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow
    Masoud Soleimani
    Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, PO Box, 14115 111, Tehran, Iran
    Nat Protoc 4:102-6. 2009
  9. doi request reprint Neurogenic differentiation of human conjunctiva mesenchymal stem cells on a nanofibrous scaffold
    Masoud Soleimani
    Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Int J Dev Biol 54:1295-300. 2010
  10. ncbi request reprint Human unrestricted somatic stem cell administration fails to protect nude mice from cisplatin-induced acute kidney injury
    Yousof Gheisari
    Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran
    Nephron Exp Nephrol 123:11-21. 2013

Collaborators

Detail Information

Publications92

  1. ncbi request reprint Multipotent mesenchymal stem cells from adult human eye conjunctiva stromal cells
    Samad Nadri
    Stem Cell Department, Stem Cell Technology Co Ltd, Tehran, Iran
    Differentiation 76:223-31. 2008
    ..Taken together, the results indicate that conjunctiva stromal-derived cells are a new source of multipotent MSCs and despite originating from an adult source, they express undifferentiated stem cell markers...
  2. ncbi request reprint An efficient method for isolation of murine bone marrow mesenchymal stem cells
    Samad Nadri
    Stem Cells and Tissue Engineering Department, Stem Cell Technology, Tehran, Iran
    Int J Dev Biol 51:723-9. 2007
    ..The data presented in this report indicated that this method can result in efficient isolation of homogenous populations of MSCs from mouse bone marrow...
  3. ncbi request reprint Characterization of fibroblast-like cells from the rat olfactory bulb
    Masoud Soleimani
    Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Int J Dev Biol 52:979-84. 2008
    ..Taken together, our data suggest that olfactory bulb tissue may constitute a new source of mesenchymal stem cells and could be used for the treatment of injury...
  4. ncbi request reprint A microRNA signature associated with chondrogenic lineage commitment
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, 14174 Tehran, Iran
    J Genet 91:171-82. 2012
    ....
  5. pmc The High Yield Expansion and Megakaryocytic Differentiation of Human Umbilical Cord Blood CD133(+) Cells
    Mahin Nikougoftar Zarif
    1 Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran 2 Iran Blood Transfusion Organization Research Center, Tehran, Iran
    Cell J 13:173-8. 2011
    ..Such strategy could be applied for optimization of CD133(+) cells expansion followed by MK differentiation...
  6. doi request reprint Unrestricted somatic stem cells as vehicle for nerve growth factor gene transfer
    Hanieh Jalali
    Department of Developmental Biology, Faculty of Biological Science, Kharazmi University, Tehran, Iran
    Neurol Res 35:553-60. 2013
    ..Based on the considerable potential of USSCs for gene delivery applications, the goal of the current study was to establish a betaNGF gene containing USSCs, which is able to secrete functional recombinant betaNGF protein...
  7. doi request reprint The effects of low-level laser irradiation on differentiation and proliferation of human bone marrow mesenchymal stem cells into neurons and osteoblasts--an in vitro study
    Masoud Soleimani
    Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Lasers Med Sci 27:423-30. 2012
    ..The effect of LLLI on differentiation and proliferation of BMSCs is dose-dependent. Considering these findings, LLLI could improve current in vitro methods of differentiating BMSCs prior to transplantation...
  8. doi request reprint A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow
    Masoud Soleimani
    Department of Hematology, Faculty of Medical Science, Tarbiat Modares University, PO Box, 14115 111, Tehran, Iran
    Nat Protoc 4:102-6. 2009
    ..5 ml of 0.25% trypsin containing 0.02% ethylenediaminetetraacetic acid for 2 min at room temperature (25 degrees C). A purified population of MSCs can be obtained 3 weeks after the initiation of culture...
  9. doi request reprint Neurogenic differentiation of human conjunctiva mesenchymal stem cells on a nanofibrous scaffold
    Masoud Soleimani
    Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Int J Dev Biol 54:1295-300. 2010
    ....
  10. ncbi request reprint Human unrestricted somatic stem cell administration fails to protect nude mice from cisplatin-induced acute kidney injury
    Yousof Gheisari
    Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran
    Nephron Exp Nephrol 123:11-21. 2013
    ..However, in spite of beneficial effects on other disease models, the renoprotective potential of human cord blood-derived unrestricted somatic stem cells (USSC) has not been examined so far...
  11. doi request reprint Biochemical and molecular characterization of hepatocyte-like cells derived from human bone marrow mesenchymal stem cells on a novel three-dimensional biocompatible nanofibrous scaffold
    Somaieh Kazemnejad
    Department of Clinical Biochemistry, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    J Gastroenterol Hepatol 24:278-87. 2009
    ..In this study, a three dimensional nanofibrous scaffold is introduced for differentiation of human bone marrow derived mesenchymal stem cells (hBMSCs) into hepatocytes...
  12. doi request reprint Electrospun nanofiber-based regeneration of cartilage enhanced by mesenchymal stem cells
    Abbas Shafiee
    Stem Cell Biology, Nanotechnology and Tissue Engineering Departments, Stem Cell Technology Research Center, Tehran, Iran
    J Biomed Mater Res A 99:467-78. 2011
    ..Our findings suggest that PVA/PCL scaffolds incorporated with MSC can serve as a suitable graft for articular cartilage reconstruction...
  13. doi request reprint Genetic modification of mesenchymal stem cells to overexpress CXCR4 and CXCR7 does not improve the homing and therapeutic potentials of these cells in experimental acute kidney injury
    Yousof Gheisari
    Department of Molecular Medicine, Pasteur Institute of Iran, Tehran, Iran
    Stem Cells Dev 21:2969-80. 2012
    ....
  14. ncbi request reprint A comparison between neurally induced bone marrow derived mesenchymal stem cells and olfactory ensheathing glial cells to repair spinal cord injuries in rat
    Saeed Oraee Yazdani
    Students Scientific Research Center of Tehran University of Medical Sciences SSRC, Tehran University of Medical Sciences, Medical Faculty, Tehran, Iran
    Tissue Cell 44:205-13. 2012
    ..In conclusion NIMSC caused both behavioral and histological improvement that potentially makes them a promising candidate for cell therapy approaches of spinal cord injuries...
  15. ncbi request reprint Effective combination of hydrostatic pressure and aligned nanofibrous scaffolds on human bladder smooth muscle cells: implication for bladder tissue engineering
    Hana Hanaee Ahvaz
    Laboratory of Membrane Biophysics and Macromolecules, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    J Mater Sci Mater Med 23:2281-90. 2012
    ..Altogether, our study reveals that proper hydrostatic pressure in combination with appropriate surface stimulation on hBSMCs causes a tissue-specific phenotype that needs to be considered in bladder tissue engineering...
  16. doi request reprint Effective combination of aligned nanocomposite nanofibers and human unrestricted somatic stem cells for bone tissue engineering
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, Iran
    Acta Pharmacol Sin 32:626-36. 2011
    ..This study aimed to investigate the interactions between matrix composition and appropriate cell type, focusing on hydroxyapatite (HA), to achieve a more effective combination for bone regeneration...
  17. doi request reprint Characterization and chondrogenic differentiation of menstrual blood-derived stem cells on a nanofibrous scaffold
    Somaieh Kazemnejad
    Department of Embryology and Stem Cells, Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
    Int J Artif Organs 35:55-66. 2012
    ....
  18. doi request reprint High yield of cells committed to the photoreceptor-like cells from conjunctiva mesenchymal stem cells on nanofibrous scaffolds
    Samad Nadri
    Medical Physics and Biomedical Engineering Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Mol Biol Rep 40:3883-90. 2013
    ....
  19. ncbi request reprint miR-146a and miR-150 promote the differentiation of CD133+ cells into T-lymphoid lineage
    Parviz Fallah
    Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, 1997775555, Tehran, Iran
    Mol Biol Rep 40:4713-9. 2013
    ..Moreover, miRNAs could be used either as substitutes or complements of the conventional differentiation protocols for higher efficiency...
  20. doi request reprint Enhanced infiltration and biomineralization of stem cells on collagen-grafted three-dimensional nanofibers
    Iman Shabani
    Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran
    Tissue Eng Part A 17:1209-18. 2011
    ..It can be concluded that COL-PES nanofibrous scaffold has potential for bone grafting because of its three-dimensional structure and bioactivity which enhance proliferation, differentiation, and infiltration of USSC...
  21. doi request reprint A comparison between osteogenic differentiation of human unrestricted somatic stem cells and mesenchymal stem cells from bone marrow and adipose tissue
    Abbas Shafiee
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    Biotechnol Lett 33:1257-64. 2011
    ..Taking together, BM-MSC showed the highest capacity for osteogenic differentiation and hold promising potential for bone tissue engineering and cell therapy applications...
  22. ncbi request reprint Isolation, characterization, and mesodermic differentiation of stem cells from adipose tissue of camel (Camelus dromedarius)
    Abdollah Mohammadi-Sangcheshmeh
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    In Vitro Cell Dev Biol Anim 49:147-54. 2013
    ..Our observation showed that like human lipoaspirate, camel adipose tissue also contain multi-potent cells and may represent an important stem cell source both for veterinary cell therapy and preclinical studies as well...
  23. doi request reprint Repair of alveolar cleft defect with mesenchymal stem cells and platelet derived growth factors: a preliminary report
    Hossein Behnia
    Department of Oral and Maxillofacial Surgery, Dental Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    J Craniomaxillofac Surg 40:2-7. 2012
    ..A mean of 51.3% fill of the bone defect was calculated 3 months post-operation. Our data suggests the use of recombinant platelet derived growth factor with hMSCs may enhance the regeneration capacity of the cells...
  24. doi request reprint Accelerated epidermal regeneration and improved dermal reconstruction achieved by polyethersulfone nanofibers
    Farshad Babaeijandaghi
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    Tissue Eng Part A 16:3527-36. 2010
    ..In this study, thick polyethersulfone (PES) nanofibrous scaffolds were prepared by fine tuning of electrospinning parameters and was evaluated for wound dressing applications...
  25. ncbi request reprint The promotion of stemness and pluripotency following feeder-free culture of embryonic stem cells on collagen-grafted 3-dimensional nanofibrous scaffold
    Seyed Mahmoud Hashemi
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    Biomaterials 32:7363-74. 2011
    ....
  26. pmc Isolation, characterization, and transplantation of bone marrow-derived cell components with hematopoietic stem cell niche properties
    Naser Ahmadbeigi
    1 Department of Hematology, Tarbiat Modares University, Tehran, Iran
    Stem Cells Dev 22:3052-61. 2013
    ..As the molecular cross-talk between HSC and niche is crucial for their proper function, the proposed method could be considered as a novel hematopoietic transplantation strategy. ..
  27. doi request reprint Induction of differentiation by down-regulation of Nanog and Rex-1 in cord blood derived unrestricted somatic stem cells
    Lida Langroudi
    Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    Mol Biol Rep 40:4429-37. 2013
    ..Considering that both transcription factors are core activators of self-renewal and also are orchestrating with other factors, our results imply a positive feedback in response to changes in the regulatory network of self-renewal...
  28. doi request reprint MicroRNAs as markers for neurally committed CD133+/CD34+ stem cells derived from human umbilical cord blood
    Maryam Hafizi
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    Biochem Genet 51:175-88. 2013
    ..These data highlight the prominent therapeutic potential of hematopoietic stem cells for use in cell therapy of neurodegenerative diseases...
  29. ncbi request reprint The aggregate nature of human mesenchymal stromal cells in native bone marrow
    Naser Ahmadbeigi
    Department of Hematology, Tarbiat Modares University, Tehran, Iran
    Cytotherapy 14:917-24. 2012
    ..This study was designed to address this issue...
  30. doi request reprint Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells
    Samad Nadri
    Stem Cells and Tissue Engineering Department, Stem Cell Technology Institute, Tehran, Iran
    Biochem Biophys Res Commun 377:423-8. 2008
    ..In conclusion, the reported results indicate that CJMSCs might be a suitable and available source for cell transplantation therapy for the central system diseases such as PD...
  31. doi request reprint Enhanced osteogenic differentiation of cord blood-derived unrestricted somatic stem cells on electrospun nanofibers
    Ehsan Seyedjafari
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    J Mater Sci Mater Med 22:165-74. 2011
    ....
  32. doi request reprint Hepatic differentiation from human mesenchymal stem cells on a novel nanofiber scaffold
    Mahboobe Ghaedi
    Department of Clinical Biochemistry, Faculty of Medical Science, Tarbiat Modares University, Tehran, IR Iran
    Cell Mol Biol Lett 17:89-106. 2012
    ..This represents the first step for the use of this nanofibrous scaffold for culture and differentiation of stem cells that may be employed for tissue engineering and cell-based therapy applications...
  33. doi request reprint Nasal septum-derived multipotent progenitors: a potent source for stem cell-based regenerative medicine
    Abbas Shafiee
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    Stem Cells Dev 20:2077-91. 2011
    ..In conclusion, NSP could be considered as an alternative autologous cell source that can bring them to the top of therapeutic applications...
  34. ncbi request reprint Dormant phase and multinuclear cells: two key phenomena in early culture of murine bone marrow mesenchymal stem cells
    Naser Ahmadbeigi
    Department of Stem Cell Biology and Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran
    Stem Cells Dev 20:1337-47. 2011
    ..These results suggest that mouse bone marrow MSCs bear several modifications when expanded in vitro, and therefore, the interpretation of the data obtained with these cells should be done more cautiously...
  35. ncbi request reprint Surface expression of CXCR4 in unrestricted somatic stem cells and its regulation by growth factors
    Naser Ahmadbeigi
    Department of Stem Cell Biology, Stem Cell Technology Research Center, Tehran, Iran
    Cell Biol Int 34:687-92. 2010
    ..The increase of CXCR4 expression, here caused by VEGF in USSCs, can improve the efficacy of stem cell therapy and transplantation after long-term culture of stem cells before clinical use...
  36. ncbi request reprint Comparative immunomodulatory properties of adipose-derived mesenchymal stem cells conditioned media from BALB/c, C57BL/6, and DBA mouse strains
    Seyed Mahmoud Hashemi
    Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    J Cell Biochem 114:955-65. 2013
    ....
  37. ncbi request reprint Mechanical characteristics of electrospun aligned PCL/PLLA nanofibrous scaffolds conduct cell differentiation in human bladder tissue engineering
    Hana Hanaee Ahvaz
    Laboratory of Membrane Biophysics and Macromolecules, Institute of Biochemistry and Biophysics, University of Tehran, P O Box 13145 1384, Tehran, Iran
    J Nanosci Nanotechnol 13:4736-43. 2013
    ..We found that mechanical forces with different frequencies exert different regulatory effects on extracellular matrices and contractile genes in hBSMCs and hBUCs that should be considered in tissue engineering strategies...
  38. doi request reprint Down-regulation of miRNA-221 triggers osteogenic differentiation in human stem cells
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    Biotechnol Lett 34:1579-87. 2012
    ..Transient modulation of mir-221 therefore suggests a mechanism for rapid induction of osteogenesis as a useful strategy for cell-based therapy...
  39. ncbi request reprint Severely damaged kidneys possess multipotent renoprotective stem cells
    Yousof Gheisari
    Department of Stem Cell and Tissue Engineering and Department of Molecular Biology and Genetic Engineering, Stem Cell Technology Research Center, Tehran, Iran
    Cytotherapy 12:303-12. 2010
    ..Several methods have been developed for the isolation of stem/progenitor cells from healthy kidneys but the existence of these cells in chronically damaged kidneys has not been noticed so far...
  40. doi request reprint In vitro immunomodulatory properties of osteogenic and adipogenic differentiated mesenchymal stem cells isolated from three inbred mouse strains
    Seyed Mahmoud Hashemi
    Department of Immunology, Tarbiat Modares University, Tehran, Iran
    Biotechnol Lett 35:135-42. 2013
    ..Adipose tissue-derived MSCs thus retain their immunomodulatory properties after in vitro OS and AD differentiation in a strain-dependent manner...
  41. doi request reprint MicroRNA 17-92 expressed by a transposone-based vector changes expression level of cell-cycle-related genes
    Marzieh Attar
    Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
    Cell Biol Int 36:1005-12. 2012
    ..Other methods of transcripts assessment confirmed miR-17-92 overexpression enhances cell proliferation...
  42. pmc The role of biodegradable engineered nanofiber scaffolds seeded with hair follicle stem cells for tissue engineering
    Leila Beigom Hejazian
    Dept of Histology and Neuroscience, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Iran Biomed J 16:193-201. 2012
    ....
  43. doi request reprint Exploring the enkephalinergic differentiation potential in adult stem cells for cell therapy and drug screening implications
    Maryam Hafizi
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    In Vitro Cell Dev Biol Anim 48:562-9. 2012
    ..Such investigations may be beneficial to ameliorate the neural-related therapeutic approaches...
  44. doi request reprint Evaluation of unrestricted somatic stem cells as a feeder layer to support undifferentiated embryonic stem cells
    Saeed Heidari Keshel
    Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Mol Reprod Dev 79:709-18. 2012
    ..Further study of hUSSC as a novel human feeder layer may lead to their incorporation into clinical methods, making them a vital part of the application of human ESCs in clinical cell therapy...
  45. doi request reprint MicroRNA signature associated with osteogenic lineage commitment
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    Mol Biol Rep 39:7569-81. 2012
    ....
  46. doi request reprint Cellular infiltration on nanofibrous scaffolds using a modified electrospinning technique
    Iman Shabani
    Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran
    Biochem Biophys Res Commun 423:50-4. 2012
    ..By this novel and simple setup, the prepared electrospun mats will allow the seeded cells to obtain a three-dimensional arrangement which is ideal for tissue engineering applications...
  47. doi request reprint Function of poly (lactic-co-glycolic acid) nanofiber in reduction of adhesion bands
    Peyman Dinarvand
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    J Surg Res 172:e1-9. 2012
    ....
  48. ncbi request reprint Molecular and ultrastructural characterization of endothelial cells differentiated from human bone marrow mesenchymal stem cells
    Maryam Jazayeri
    Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran
    Cell Biol Int 32:1183-92. 2008
    ..These results indicate that the capacity of endothelial cells differentiated from hBMSCs in formation of vascular system is consistent with molecular and structural development...
  49. pmc Poly (epsilon-caprolactone) nanofibrous ring surrounding a polyvinyl alcohol hydrogel for the development of a biocompatible two-part artificial cornea
    Haleh Bakhshandeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Int J Nanomedicine 6:1509-15. 2011
    ..These results confirmed that the polymeric artificial cornea showed suitable physical properties and good biocompatibility and epithelialization ability...
  50. ncbi request reprint Investigation of deregulated genes of Notch signaling pathway in human T cell acute lymphoblastic leukemia cell lines and clinical samples
    Mahdi Paryan
    Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, P O Box 1316943551, Tehran, Iran
    Mol Biol Rep 40:5531-40. 2013
    ....
  51. doi request reprint Nanofiber-based polyethersulfone scaffold and efficient differentiation of human induced pluripotent stem cells into osteoblastic lineage
    Abdolreza Ardeshirylajimi
    Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
    Mol Biol Rep 40:4287-94. 2013
    ..These cells and PES scaffold were demonstrated to have great efficiency for treatment of bone damages and lesions...
  52. doi request reprint In vitro differentiation of human cord blood-derived unrestricted somatic stem cells into hepatocyte-like cells on poly(epsilon-caprolactone) nanofiber scaffolds
    Seyed Mahmoud Hashemi
    Department of Stem Cell and Tissue Engineering, Stem Cell Technology Co Ltd, Tehran, Iran
    Cells Tissues Organs 190:135-49. 2009
    ..In the present study, we show that hepatocyte-like cells differentiated from USSCs on the PCL nanofiber scaffold can be candidate for tissue engineering and cell therapy of hepatic tissues...
  53. doi request reprint BD PuraMatrix peptide hydrogel as a culture system for human fetal Schwann cells in spinal cord regeneration
    Fateme Moradi
    Department of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Neurosci Res 90:2335-48. 2012
    ....
  54. pmc The effect of topography on differentiation fates of matrigel-coated mouse embryonic stem cells cultured on PLGA nanofibrous scaffolds
    Mohammad Massumi
    Department of Animal and Marine Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
    Tissue Eng Part A 18:609-20. 2012
    ..It was concluded that the topomorpholocial cues such as roughness and alignment should be considered in addition to other scaffolds properties to design an efficient electrospun scaffold for specific tissue engineering...
  55. doi request reprint New approach to bone tissue engineering: simultaneous application of hydroxyapatite and bioactive glass coated on a poly(L-lactic acid) scaffold
    Peyman Dinarvand
    Stem Cell Biology Department, Stem Cell Technology Research Center, Tehran, Iran
    ACS Appl Mater Interfaces 3:4518-24. 2011
    ..These bioceramic-coated scaffolds can be used as new bone-graft substitutes capable of efficiently inducing osteoconduction and osseointegration in orthopedic fractures and defects...
  56. doi request reprint Stem cell-conditioned medium does not protect against kidney failure
    Yousof Gheisari
    Department of Stem Cell Biology, Stem Cell Technology Research Center, Tehran, Iran
    Cell Biol Int 35:209-13. 2011
    ..Neither MSC- nor USSC-conditioned media were effective in protecting against kidney injury in our study. Possible explanations for our observations are offered, and related literature is reviewed...
  57. doi request reprint Morpholino Oligo Antisense efficiently suppresses BCR/ABL and cell proliferation in CML: specific inhibition of BCR-ABL gene expression by Morpholino Oligo Antisense in BCR-ABL(+) cells
    Mahmoud Haririan
    Department of Hematology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
    Hematology 17:28-34. 2012
    ..The results indicate that Morpholino Oligo Antisense was able to inhibit p210(bcr-abl), but did not induce apoptosis due to co-silencing of BCR...
  58. ncbi request reprint miRNAs expressed differently in cancer stem cells and cancer cells of human gastric cancer cell line MKN-45
    Azadeh Fahim Golestaneh
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    Cell Biochem Funct 30:411-8. 2012
    ..These miRNAs may be promising objects for targeting CSCs specifically and efficiently...
  59. ncbi request reprint Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells
    Mohammad Massumi
    Induced Pluripotent Stem Cell Biotechnology Team, Stem Cells Department, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Stem Cells Biology Department, Stem Cell Technology Research Center, Tehran, Iran Department of Physiology, University of Toronto, Toronto, Ontario, Canada Electronic address
    Exp Cell Res 322:51-61. 2014
    ..The comparative findings suggest that although both Wnt3a/Activin A signaling and IDE1 molecule could be used for differentiation of iPS into DE cells, the DE-inducing effect of Wnt3a/Activin A was statistically higher than IDE1. ..
  60. ncbi request reprint Establishment of lentiviral-vector-mediated model of human alpha-1 antitrypsin delivery into hepatocyte-like cells differentiated from mesenchymal stem cells
    Mahboobe Ghaedi
    Department of Clinical Biochemistry, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    Tissue Cell 42:181-9. 2010
    ....
  61. ncbi request reprint An in vitro assay to evaluate the immunomodulatory effects of unrestricted somatic stem cells
    Hasan Ebrahimi
    Department of Hematology, Tarbiat Modares University, Tehran, Iran
    Iran J Immunol 7:30-8. 2010
    ..Therefore, potential exists for their use in the suppression of immune response after transplantation surgery...
  62. doi request reprint Mesenchymal stem cells as an appropriate feeder layer for prolonged in vitro culture of human induced pluripotent stem cells
    Parvaneh Havasi
    Department of Developmental Biology, Faculty of Biological Science, Kharazmi University, P O Box 15614, Tehran, Iran
    Mol Biol Rep 40:3023-31. 2013
    ..Altogether our results suggest human mesenchymal stem cells as an appropriate feeder layer for human iPSCs culture for clinical applications and cell therapy...
  63. ncbi request reprint Isolation of stem cells from adult rat kidneys
    Yousof Gheisari
    Stem Cell Technology Company, Tehran, Iran
    Biocell 33:33-8. 2009
    ..These cells also expressed Nucleostemin, Cyclin D1, Notch1 and Survivin which are commonly expressed in stem cells. The results of the current work show that the adult kidney contains a population of multipotent stem cells...
  64. ncbi request reprint Bladder tissue engineering using biocompatible nanofibrous electrospun constructs: feasibility and safety investigation
    Nasser Shakhssalim
    Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Urol J 9:410-9. 2012
    ..To investigate the feasibility and safety of using biocompatible, nanofibrous electrospun polycaprolactone (PCL) and combination of polylactic acid (PLLA) and PCL mats in a canine model...
  65. doi request reprint Secondary repair of alveolar clefts using human mesenchymal stem cells
    Hossein Behnia
    Department of Oral and Maxillofacial Surgery, Taleghani Hospital, Dental Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:e1-6. 2009
    ..6% presentation of bone integrity. The available data revealed the conventional bone substitute was not a suitable scaffold for the MSC-induced bone regeneration...
  66. doi request reprint Safety and possible outcome assessment of autologous Schwann cell and bone marrow mesenchymal stromal cell co-transplantation for treatment of patients with chronic spinal cord injury
    Saeed Oraee Yazdani
    Functional Neurosurgery Research Center, Department of Neurosurgery, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Cytotherapy 15:782-91. 2013
    ..Therefore, many recent studies have used combination strategies for spinal cord regeneration...
  67. doi request reprint Evaluation of H3 histone methylation and colony formation in erythroid progenitors treated with thalidomide and sodium butyrate
    Ali Dehghani Fard
    Department of Hematology and Blood Banking, Tarbiat Modares University, Tehran, Iran
    Lab Hematol 19:1-5. 2013
    ..In both conditions, up-regulation of hemoglobin F through demethylation can alleviate the symptoms. This can be attained with drugs such as thalidomide and sodium butyrate...
  68. doi request reprint Targeting of the signal transducer Smo links microRNA-326 to the oncogenic Hedgehog pathway in CD34+ CML stem/progenitor cells
    Sadegh Babashah
    Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
    Int J Cancer 133:579-89. 2013
    ....
  69. ncbi request reprint Neural differentiation of mouse embryonic stem cells on conductive nanofiber scaffolds
    Mahboubeh Kabiri
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    Biotechnol Lett 34:1357-65. 2012
    ..We propose that the conductive scaffold could be a useful tool for the generation of neural tissue mimics in vitro and potentially as a scaffold for the repair of neural defects in vivo...
  70. doi request reprint Clinical grade cultivation of human Schwann cell, by the using of human autologous serum instead of fetal bovine serum and without growth factors
    Hamid Reza Aghayan
    Endocrinology and Metabolism Research Center and Brain and Spinal Cord Injury Repair Research Center, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Avenue, 14114, Tehran, Iran
    Cell Tissue Bank 13:281-5. 2012
    ..We also recommended all cell preparation facilities to adhere to the GMP and other similar quality disciplines especially in the preparation of clinically-used cell products...
  71. doi request reprint Proliferation and differentiation of mesenchymal stem cell on collagen sponge reinforced with polypropylene/polyethylene terephthalate blend fibers
    Sara Mohajeri
    Polymer Group, Department of Chemical Engineering, Tarbiat Modares University, Tehran, Iran
    Tissue Eng Part A 16:3821-30. 2010
    ..We conclude that incorporation of PP/PET fibers not only improves the mechanical properties of collagen sponge, but also enables mesenchymal stem cells to positively improve their proliferation and differentiation...
  72. doi request reprint Role of poly-L-lysine-coated plates and fetal calf serum concentration in sheep chondroprogenitor cell culturing
    Amir Atashi
    Hematology Department, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran
    J Artif Organs 12:118-22. 2009
    ..Taken together, the results indicated that PLL may have some effect on the adhesive properties of chondroprogenitor cells and could be used for cartilage engineering...
  73. ncbi request reprint Isolation murine mesenchymal stem cells by positive selection
    Samad Nadri
    Stem Cells Department, Stem Cell Technology, CO, Tehran, Iran
    In Vitro Cell Dev Biol Anim 43:276-82. 2007
    ..We have shown that murine bone marrow-derived CD34(+) cells with plastic adherent properties and capability of differentiating into skeletal lineages in vitro are MSCs...
  74. doi request reprint Improved infiltration of stem cells on electrospun nanofibers
    Iman Shabani
    Polymer Engineering Department, Amirkabir University of Technology, P O Box 15875 4413, Tehran, Iran
    Biochem Biophys Res Commun 382:129-33. 2009
    ..The cells had normal morphology on nanofibers and showed very high infiltration through collagen grafted PES nanofibers. This infiltration capability is very useful and needed to make 3D scaffolds in tissue engineering...
  75. doi request reprint A comparison of DNA damage induced by aflatoxin B1 in hepatocyte-like cells, their progenitor mesenchymal stem cells and CD34(+) cells isolated from umbilical cord blood
    Masoumeh Ghaderi
    Department of Biochemistry, Tarbiat Modares University, Tehran, Islamic Republic of Iran
    Mutat Res 719:14-20. 2011
    ..These data are useful in better understanding the susceptibility/resistance of stem cells in the process of differentiation to environmental toxicants...
  76. doi request reprint Isolation and ex vivo expansion of human umbilical cord blood-derived CD34+ stem cells and their cotransplantation with or without mesenchymal stem cells
    Bahman Delalat
    Department of Hematology, School of Medical Sciences Faculty, Tarbiat Modares University, PO Box 14115 111, Tehran, Iran
    Hematology 14:125-32. 2009
    ..01). In conclusion the results showed that two cytokines (SCF, TPO) were sufficient for expansion of UCB CD34(+) cells and cotransplantation of MSC with UCB CD34(+) cells, promoting engraftment of UCB CD34(+) cells...
  77. ncbi request reprint In vitro differentiation of cord blood unrestricted somatic stem cells expressing dopamine-associated genes into neuron-like cells
    Mohammad Fallahi-Sichani
    Department of Biotechnology, University College of Science, University of Tehran, Tehran 14155 6455, Iran
    Cell Biol Int 31:299-303. 2007
    ..The expression of dopamine-associated genes suggests that these cells may be potential candidates to be used for cell therapy of PD...
  78. ncbi request reprint Effects of low level laser therapy on proliferation and neurotrophic factor gene expression of human schwann cells in vitro
    Saeed Oraee Yazdani
    Neuroscience Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
    J Photochem Photobiol B 107:9-13. 2012
    ..Our results demonstrate that low level laser therapy stimulate human schwann cell proliferation and NGF gene expression in vitro...
  79. pmc Prediction of oocyte developmental competence in ovine using glucose-6-phosphate dehydrogenase (G6PDH) activity determined at retrieval time
    Abdollah Mohammadi-Sangcheshmeh
    Department of Transgenic Animal Science, Stem Cell Technology Research Center, Tehran, Iran
    J Assist Reprod Genet 29:153-8. 2012
    ..To determine whether G6PDH-activity measured by Brilliant Cresyl Blue known as BCB dye, predicts developmental competence within cohorts of ovine oocytes...
  80. doi request reprint The reversal of hyperglycemia after transplantation of mouse embryonic stem cells induced into early hepatocyte-like cells in streptozotocin-induced diabetic mice
    Nasim Beigi Boroujeni
    Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Tissue Cell 43:75-82. 2011
    ..The findings declare that induced mESCs into endoderm and early hepatocyte-like cells, are appropriate candidate for regenerative therapy of pancreatic islets in type I diabetes...
  81. doi request reprint Polyurethane/polycaprolactane blend with shape memory effect as a proposed material for cardiovascular implants
    Shadi Hassan Ajili
    Department of Polymer Engineering, Faculty of Engineering, Tarbiat Modares University, Tehran, Iran
    Acta Biomater 5:1519-30. 2009
    ..The results showed that the blend supported cell adhesion and proliferation, which indicated good biocompatibility. Our results suggested that this blend might be a potential material as a stent implant...
  82. ncbi request reprint In vitro cardiomyogenic potential of human umbilical vein-derived mesenchymal stem cells
    Mehdi Kadivar
    Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran
    Biochem Biophys Res Commun 340:639-47. 2006
    ..These observations confirm that human umbilical cord-derived mesenchymal stem cells can be chemically transformed into cardiomyocytes and can be considered as a source of cells for cellular cardiomyoplasty...
  83. ncbi request reprint Effects of stem cells and granulocyte colony stimulating factor in reperfusion injury
    Mohsen Nafar
    Department of Nephrology, Shahid Labbafinejad Medical Center and Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Iran J Kidney Dis 4:207-13. 2010
    ..We aimed to investigate the role of GCSF as an alternative therapeutic option instead of mesenchymal stem cells (MSCs) in reperfusion injury...
  84. doi request reprint Differential expression of glutathione S-transferases P1-1 and A1-1 at protein and mRNA levels in hepatocytes derived from human bone marrow mesenchymal stem cells
    Abdolamir Allameh
    Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Aleahmad Chamran Crossing, Tehran 14115 111, Iran
    Toxicol In Vitro 23:674-9. 2009
    ..These data may suggest that hepatogenic differentiation of human bone marrow MSC is accompanied with the regulation of factors participating in GSH conjugation pathway...
  85. ncbi request reprint The similar effect of transplantation of marrow-derived mesenchymal stem cells with or without prior differentiation induction in experimental myocardial infarction
    Seyed Mahdi Nassiri
    Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    J Biomed Sci 14:745-55. 2007
    ..There is no need for prior differentiation induction of marrow-derived MSCs before transplantation and peri-infarct implantation of MSCs can efficiently regenerate the infarcted myocardium and improve cardiac function...
  86. pmc A comparative study on nonviral genetic modifications in cord blood and bone marrow mesenchymal stem cells
    Behnaz Bakhshandeh
    Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran
    Cytotechnology 64:523-40. 2012
    ....
  87. doi request reprint Inhibition of cyclooxygenase-2 and inducible nitric oxide synthase by silymarin in proliferating mesenchymal stem cells: comparison with glutathione modifiers
    Hamidreza Ahmadi-Ashtiani
    Department of Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, POB 14115 111, Tehran, Islamic Republic of Iran
    J Nat Med 66:85-94. 2012
    ..It appears that glutathione is the main target of silymarin, and in consequence iNOS and COX-2 are affected in response to silymarin treatment...
  88. doi request reprint Sinus augmentation using human mesenchymal stem cells loaded into a beta-tricalcium phosphate/hydroxyapatite scaffold
    Yadollah Soleymani Shayesteh
    Dental Faculty, Tehran University of Medical Sciences, Tehran, Iran
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:203-9. 2008
    ..This clinical study was based on the hypothesis that the clinical effectiveness of adult mesenchymal stem cells (MSCs) loaded to the biphasic scaffold...
  89. ncbi request reprint Repair of spinal cord injury by co-transplantation of embryonic stem cell-derived motor neuron and olfactory ensheathing cell
    Mohammad Salehi
    Dept of Anatomy, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Iran Biomed J 13:125-35. 2009
    ..In this study, we evaluated the co-transplantation of olfactory ensheathing cells (OEC) and embryonic stem (ES) cell-derived motor neurons (ESMN) on contused SCI...
  90. doi request reprint The oncogenic and tumour suppressive roles of microRNAs in cancer and apoptosis
    Sadegh Babashah
    Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
    Eur J Cancer 47:1127-37. 2011
    ..Given emerging evidence that points to oncogenic and tumour suppressive roles of miRNAs in cancer and apoptosis, it is thought that manipulating miRNA expression level may be a potential therapeutic strategy for curing cancer...
  91. doi request reprint OCT4B1, a novel spliced variant of OCT4, generates a stable truncated protein with a potential role in stress response
    Ehsan Farashahi Yazd
    Molecular Genetics Department, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
    Cancer Lett 309:170-5. 2011
    ..Furthermore, our data demonstrated a cytoplasmic distribution for both isoforms. Interestingly, the expression ratio of OCT4B1/OCT4B transcripts and proteins was significantly elevated under the heat-stress condition...