Affiliation: Tarbiat Modarres University
Mohaqiq M, Movahedin M, Mazaheri Z, Amirjannati N. In vitro transplantation of spermatogonial stem cells isolated from human frozen-thawed testis tissue can induce spermatogenesis under 3-dimensional tissue culture conditions. Biol Res. 2019;52:16 pubmed publisher
..These results suggest that the slow freezing of SSCs can support the induction of spermatogenesis to produce haploid cells under the 3-dimensional testicular tissue culture. ..
Mohaqiq M, Movahedin M, Mazaheri Z, Amirjannati N. Successful Human Spermatogonial Stem Cells Homing in Recipient Mouse Testis after In Vitro Transplantation and Organ Culture. Cell J. 2019;20:513-520 pubmed publisher
..05). Testicular tissue culture conditions after SSC transplantation can help these cells subside on the seminiferous tubule basement membrane. ..
Makoolati Z, Movahedin M, Forouzandeh Moghadam M. Proliferation in culture of primordial germ cells derived from embryonic stem cell: induction by retinoic acid. Biosci Rep. 2016;36: pubmed publisher
..Based on the results, it seems that in the presence of 3 ?M RA on top of the STO feeder layer cells, the majority of the cells transdifferentiated into germ cells were PGCs. ..
Makoolati Z, Movahedin M, Forouzandeh Moghadam M, Naghdi M, Koruji M. Embryonic stem cell derived germ cells induce spermatogenesis after transplantation into the testes of an adult mouse azoospermia model. Clin Sci (Lond). 2017;131:2381-2395 pubmed publisher
..The number of spermatogonia and the mass of the testes were higher in transplanted testes relative to the control group. It seems that transplantation of these cells can be useful in infertility treatment. ..
Majidi Gharenaz N, Movahedin M, Mazaheri Z. Effects of Re-Vitrification of Mouse Morula and Early Blastocyst Stages on Apoptotic Gene Expression and Developmental Potential. Cell J. 2018;19:614-619 pubmed publisher
..05). Expressions of the Bax and Bcl-2 genes showed no significant difference between the two re-vitrified groups. Based on our study, re-vitrification could affect developmental rate and expressions of the Bax and Bcl2 genes. ..
Mohaqiq M, Movahedin M, Mokhtari Dizaji M, Mazaheri Z. Upregulation of Integrin-Î±6 and Integrin-Î²1 Gene Expressions in Mouse Spermatogonial Stem Cells after Continues and Pulsed Low Intensity Ultrasound Stimulation. Cell J. 2018;19:634-639 pubmed publisher
..These results suggested that LIUS and LIUPS treatment had good effect on SSCs proliferation and colonization, based on the gene-specific marker expression during 21 days culture in vitro. ..