Research Topics
| Siavoush DastmalchiSummaryAffiliation: Tabriz University of Medical Sciences Country: Iran Publications
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Detail Information
Publications
Presence of transient helical segments in the galanin-like peptide evident from (1)H NMR, circular dichroism, and prediction studiesSiavoush Dastmalchi
School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
J Struct Biol 146:261-71. 2004..Secondary structure prediction methods also predict the presence of two helical regions in the sequence of GALP overlapping reasonably with those regions identified as nascent helical structures by experimental methods...
Modelling the structures of G protein-coupled receptors aided by three-dimensional validationSiavoush Dastmalchi
School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
BMC Bioinformatics 9:S14. 2008..We highlight the value of the method by applying it to the Baldwin GPCR template but the method can, in principle, be applied to any low- or high-resolution membrane protein template or structure...
Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonistsSiavoush Dastmalchi
School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran
J Mol Graph Model 26:834-44. 2008..The results of this investigation are expected to be useful in the process of design and development of new potent H3 receptor antagonists...
Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analysesSiavoush Dastmalchi
School of Pharmacy, and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
FEBS J 274:2653-60. 2007....
Identification of new peptide ligands for epidermal growth factor receptor using phage display and computationally modeling their mode of bindingMaryam Hamzeh-Mivehroud
Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Chem Biol Drug Des 79:246-59. 2012..The calculated values for the binding energies were found to be similar to our experimental data and those of previously reported studies...
Naproxen-eudragit RS100 nanoparticles: preparation and physicochemical characterizationKhosro Adibkia
Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Colloids Surf B Biointerfaces 83:155-9. 2011....
Kinetic analysis of chlorpropamide dissolution from solid dispersionsMohammad Barzegar-Jalali
Department of Pharmaceutics, School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Drug Dev Ind Pharm 33:63-70. 2007..There was a quantitative relation between the model parameter and the ratio of carrier to drug which could be of value in dissolution rate prediction...
QSPR models for the prediction of apparent volume of distributionTaravat Ghafourian
Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Int J Pharm 319:82-97. 2006..The structural descriptors in the model can be interpreted based on the known mechanisms of distribution and the molecular structures of the drugs...
Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complexSiavoush Dastmalchi
School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia Biotechnology Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Protein Sci 21:1768-74. 2012....
Synthesis and anti-leishmanial activity of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-amines containing N-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] moietiesAzar Tahghighi
Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Eur J Med Chem 50:124-8. 2012..The most active compound against promostigotes was found to be 4-methylbenzyl analog 3i, which significantly decreases the number of intracellular amastigotes per macrophage, percentage of macrophage infectivity and infectivity index...
Non-specific translocation of peptide-displaying bacteriophage particles across the gastrointestinal barrierMaryam Hamzeh-Mivehroud
School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Eur J Pharm Biopharm 70:577-81. 2008..There are, however, some residue types underrepresented which could be due to specific GI selection mechanisms and/or their effects on the amplification rate for phages bearing those residues...
Enhancing dissolution, serum concentrations and hypoglycemic effect of glibenclamide using solvent deposition techniqueSiavoush Dastmalchi
Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
J Pharm Pharm Sci 8:175-81. 2005..Strong quantitative correlations were established between dissolution parameter and parameters related to serum concentrations as well as hypoglycemic effects...
