Siavoush Dastmalchi

Summary

Affiliation: Tabriz University of Medical Sciences
Country: Iran

Publications

  1. pmc Comparison of 4-chloro-2-nitrophenol adsorption on single-walled and multi-walled carbon nanotubes
    Ali Mehrizad
    PH, D Student, Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
    Iranian J Environ Health Sci Eng 9:5. 2012
  2. ncbi request reprint Presence of transient helical segments in the galanin-like peptide evident from (1)H NMR, circular dichroism, and prediction studies
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Struct Biol 146:261-71. 2004
  3. ncbi request reprint Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses
    Siavoush Dastmalchi
    School of Pharmacy, and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    FEBS J 274:2653-60. 2007
  4. ncbi request reprint Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran
    J Mol Graph Model 26:834-44. 2008
  5. pmc Modelling the structures of G protein-coupled receptors aided by three-dimensional validation
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    BMC Bioinformatics 9:S14. 2008
  6. doi request reprint Identification of new peptide ligands for epidermal growth factor receptor using phage display and computationally modeling their mode of binding
    Maryam Hamzeh-Mivehroud
    Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Biol Drug Des 79:246-59. 2012
  7. doi request reprint New 5-(nitroheteroaryl)-1,3,4-thiadiazols containing acyclic amines at C-2: synthesis and SAR study for their antileishmanial activity
    Azar Tahghighi
    Department of Medicinal Chemistry, School of Pharmacy and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    J Enzyme Inhib Med Chem 28:843-52. 2013
  8. doi request reprint Naproxen-eudragit RS100 nanoparticles: preparation and physicochemical characterization
    Khosro Adibkia
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 83:155-9. 2011
  9. ncbi request reprint Kinetic analysis of chlorpropamide dissolution from solid dispersions
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:63-70. 2007
  10. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006

Collaborators

Detail Information

Publications16

  1. pmc Comparison of 4-chloro-2-nitrophenol adsorption on single-walled and multi-walled carbon nanotubes
    Ali Mehrizad
    PH, D Student, Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
    Iranian J Environ Health Sci Eng 9:5. 2012
    ..The observed changes in the standard Gibbs free energy, standard enthalpy and standard entropy showed that the adsorption of 4C2NP onto SWCNTs and MWCNTs is spontaneous and exothermic in the temperature range of 298-328 K...
  2. ncbi request reprint Presence of transient helical segments in the galanin-like peptide evident from (1)H NMR, circular dichroism, and prediction studies
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    J Struct Biol 146:261-71. 2004
    ..Secondary structure prediction methods also predict the presence of two helical regions in the sequence of GALP overlapping reasonably with those regions identified as nascent helical structures by experimental methods...
  3. ncbi request reprint Prediction of rotational orientation of transmembrane helical segments of integral membrane proteins using new environment-based propensities for amino acids derived from structural analyses
    Siavoush Dastmalchi
    School of Pharmacy, and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    FEBS J 274:2653-60. 2007
    ....
  4. ncbi request reprint Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, Iran
    J Mol Graph Model 26:834-44. 2008
    ..The results of this investigation are expected to be useful in the process of design and development of new potent H3 receptor antagonists...
  5. pmc Modelling the structures of G protein-coupled receptors aided by three-dimensional validation
    Siavoush Dastmalchi
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    BMC Bioinformatics 9:S14. 2008
    ..We highlight the value of the method by applying it to the Baldwin GPCR template but the method can, in principle, be applied to any low- or high-resolution membrane protein template or structure...
  6. doi request reprint Identification of new peptide ligands for epidermal growth factor receptor using phage display and computationally modeling their mode of binding
    Maryam Hamzeh-Mivehroud
    Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Biol Drug Des 79:246-59. 2012
    ..The calculated values for the binding energies were found to be similar to our experimental data and those of previously reported studies...
  7. doi request reprint New 5-(nitroheteroaryl)-1,3,4-thiadiazols containing acyclic amines at C-2: synthesis and SAR study for their antileishmanial activity
    Azar Tahghighi
    Department of Medicinal Chemistry, School of Pharmacy and Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    J Enzyme Inhib Med Chem 28:843-52. 2013
    ..The most active derivatives were hydroxypropylamino- and methoxypropylamino- analogs of 5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazole (compounds 29 and 32, respectively) with highest selectivity index (SI >12). ..
  8. doi request reprint Naproxen-eudragit RS100 nanoparticles: preparation and physicochemical characterization
    Khosro Adibkia
    Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Colloids Surf B Biointerfaces 83:155-9. 2011
    ....
  9. ncbi request reprint Kinetic analysis of chlorpropamide dissolution from solid dispersions
    Mohammad Barzegar-Jalali
    Department of Pharmaceutics, School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Drug Dev Ind Pharm 33:63-70. 2007
    ..There was a quantitative relation between the model parameter and the ratio of carrier to drug which could be of value in dissolution rate prediction...
  10. ncbi request reprint QSPR models for the prediction of apparent volume of distribution
    Taravat Ghafourian
    Drug Design and Chemometrics Laboratory, Drug Applied Research Centre and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Pharm 319:82-97. 2006
    ..The structural descriptors in the model can be interpreted based on the known mechanisms of distribution and the molecular structures of the drugs...
  11. doi request reprint Structure-based investigation of rat aldehyde oxidase inhibition by flavonoids
    Maryam Hamzeh-Mivehroud
    Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Xenobiotica 43:661-70. 2013
    ..However, the glycosylated flavonoids showed relatively weaker inhibition which may be attributed to their hindered binding into the active site of AO by bulky sugar groups...
  12. pmc In silico Evaluation of Crosslinking Effects on Denaturant m(eq) values and ΔCp upon Protein Unfolding
    Maryam Hamzeh-Mivehroud
    Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Avicenna J Med Biotechnol 4:23-34. 2012
    ..The results of the current study were in close agreement with those obtained from the previous studies...
  13. pmc Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex
    Siavoush Dastmalchi
    School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia
    Protein Sci 21:1768-74. 2012
    ....
  14. doi request reprint Synthesis and anti-leishmanial activity of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-amines containing N-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] moieties
    Azar Tahghighi
    Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Med Chem 50:124-8. 2012
    ..The most active compound against promostigotes was found to be 4-methylbenzyl analog 3i, which significantly decreases the number of intracellular amastigotes per macrophage, percentage of macrophage infectivity and infectivity index...
  15. doi request reprint Non-specific translocation of peptide-displaying bacteriophage particles across the gastrointestinal barrier
    Maryam Hamzeh-Mivehroud
    School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    Eur J Pharm Biopharm 70:577-81. 2008
    ..There are, however, some residue types underrepresented which could be due to specific GI selection mechanisms and/or their effects on the amplification rate for phages bearing those residues...
  16. ncbi request reprint Enhancing dissolution, serum concentrations and hypoglycemic effect of glibenclamide using solvent deposition technique
    Siavoush Dastmalchi
    Department of Medicinal Chemistry, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
    J Pharm Pharm Sci 8:175-81. 2005
    ..Therefore, to enhance the drug dissolution, serum concentrations and its hypoglycemic effects, it was formulated as solid dispersions and evaluated the relevant in vitro and in vivo parameters...